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Dietary supplement

Glutamine Drive Unflavored Ingredients & Drug Interactions

by Nutrex Research Black Series

Glutamine Drive Unflavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Drive Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Drive Unflavored is a dietary supplement by Nutrex Research Black Series with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Drive Unflavored by Nutrex Research Black Series

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Drive Unflavored by Nutrex Research Black Series — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glutamine Drive Unflavored by Nutrex Research Black Series

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Glutamine Drive Unflavored is a single-ingredient powder: L-glutamine, an amino acid your body naturally makes and uses for gut health, immune function, and muscle recovery. The product contains no other active ingredients and no inactive fillers or binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: reduce muscle breakdown and enhance recovery.
  • We looked for evidence on: Exercise-induced muscle damage, Athletic performance, Postoperative recovery, muscle repair, muscle protein synthesis, training recovery.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

L-glutamine is rated effective for sickle cell disease. It's possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma based on the evidence we hold.

If you're considering it for one of those reasons, talk it over with your doctor about whether the research supports it for your situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults. The most common side effects are digestive—belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting—especially at higher doses (10–30 grams daily).

Headache and musculoskeletal pain have also been reported. A few cases of dizziness and mood changes (mania or hypomania) have been noted in people with bipolar disorder.

The product is rated likely safe in pregnancy and lactation based on available data. However, if you have kidney or liver disease, you should only use it under medical supervision.

If you're breastfeeding, there isn't enough safety data, so talk with your doctor or pharmacist before taking a supplement dose.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure drugs), double-check them with your doctor or pharmacist before starting this product. Glutamine might theoretically reduce how well they work, though this hasn't been reported in people yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine Drive is a straightforward single-ingredient powder useful for sickle cell disease and possibly helpful for recovery after surgery or during critical illness. If you take seizure medication, check with your doctor or pharmacist first—there's a theoretical interaction that hasn't shown up in patients yet, but it's worth confirming it's safe for you.

For kidney or liver disease, get medical supervision before using it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Drive Unflavored, straight from the product label.

Brand Nutrex Research Black Series
Barcode (UPC) 853237000974
Net contents 2.2 lbs; 1000 Gram(s)
Market status On market
Date entered into DSLD Jul 24, 2019
DSLD ID 203784
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Drive Unflavored by Nutrex Research Black Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
200
UPC/BARCODE
853237000974
IngredientAmount% DV
L-Glutamine5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Glutamine Drive Product Highlights 5 grams of pure L-Glutamine to quickly replenish muscle glutamine

Supplementing with extra L-Glutamine helps maintain high muscular glutamine levels which in turn reduces muscle breakdown and speeds up muscle tissue repair. Regular consumption of L-Glutamine helps maximize your muscle building results. Glutamine Drive consists of pure L-Glutamine.

General Statements

Helps reduce muscle breakdown caused by training, diet and stress Enhances muscle recovery and supports muscle tissue growth

Glutamine is a vital amino acid and accounts for 60% of all amino acids in muscle tissue.

Regular intense training, dieting, and stress deplete your muscles' natural glutamine stores. This process breaks down muscle tissue. The ability to reverse it by recovering from training and repairing muscle tissue at an accelerated pace is crucial to building up muscle and strength.

Reduces muscle breakdown Supports muscle growth Enhances recovery

As individuals vary so will results from using this product.

Suggested/Recommended/Usage/Directions

Ideal for daily consumption Unflavored so it can be added to any sports drink

Recommended Use: Mix 1 scoop with 6-8 oz of water or any beverage of your choice. Take 2 servings daily: One in the morning upon rising and one before going to bed. On training days take an extra serving following your workout. Glutamine Drive is unflavored and can be easily added to any beverage of your choice.

FDA Statement of Identity

Dietary Supplement

Precautions

Allergen Warning: Manufactured on equipment that processes products containing milk, egg, soybeans, fin fish and wheat.

Warning: Do not use if pregnant or nursing.

Stay well hydrated throughout the day.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Drive Unflavored by Nutrex Research Black Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Drive Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Drive Unflavored by Nutrex Research Black Series

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container200 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Glutamine Drive Unflavored by Nutrex Research Black Series Drug Interactions

Want to check YOUR meds against Glutamine Drive Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine Drive Unflavored interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Drive Unflavored interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Drive Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Drive Unflavored, from the product label.

Nutrex Research Black Series

See all Nutrex Research Black Series products
Name
Nutrex Research, Inc.
City
Oviedo
State
FL
ZipCode
32765
Phone Number
1-888-368-8739
Web Address
Nutrex.com
Pharmacist Counseling Corner

Glutamine Drive Unflavored by Nutrex Research Black Series: Common Questions

Does Glutamine Drive Unflavored by Nutrex Research Black Series interact with any medications?
Yes. Based on its ingredients, Glutamine Drive Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Drive Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is L-glutamine, and what does it do?
L-glutamine is an amino acid—a building block your body makes naturally. It supports gut health, immune function, and muscle recovery. This powder gives you a concentrated dose of it.
Will this upset my stomach?
L-glutamine is generally well tolerated, but digestive side effects like bloating, constipation, diarrhea, and nausea are common, especially at higher doses. Starting with a smaller amount and spacing doses out can help.
Is it safe to take while pregnant or breastfeeding?
L-glutamine is rated likely safe in pregnancy based on available data. While breastfeeding, there isn't enough safety information, so talk with your doctor or pharmacist for personalized advice before taking a supplement dose.
Will it help my HIV-related weight loss?
L-glutamine is possibly effective for HIV/AIDS-related wasting based on the evidence we hold, but it's not a guaranteed treatment. Discuss whether it's a good fit for your situation with your doctor.
Can I take this if I have kidney or liver problems?
You should only use L-glutamine under medical supervision if you have kidney or liver disease. Check with your doctor or pharmacist before starting.
Does this powder have fillers or other ingredients?
No—Glutamine Drive Unflavored is just L-glutamine. There are no inactive ingredients, fillers, or binders in it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Drive Unflavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Drive Unflavored label
Go deeper

The Full Monographs Behind Glutamine Drive Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Drive Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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