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Dietary supplement

Glutamine Powder Ingredients & Drug Interactions

by CHK Nutrition

Glutamine Powder label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Powder is a dietary supplement by CHK Nutrition with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Powder by CHK Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Powder by CHK Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glutamine Powder by CHK Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine powder. Glutamine is an amino acid — one of the building blocks your body uses to make protein.

Your body makes some on its own, but during illness, injury, or intense physical stress, your cells can use more than you produce.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glutamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Natural Medicines).

The data shows glutamine is effective for sickle cell disease. It's rated possibly effective for HIV/AIDS-related wasting, postoperative (after-surgery) recovery, and critical illness from trauma.

The evidence for these uses isn't as solid as it is for sickle cell disease, but the research suggests it may help in those situations.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated when taken by mouth. The most common side effects are digestive — belching, bloating, constipation, diarrhea, gas, nausea, and vomiting — plus headache and muscle pain.

These tend to happen at higher doses; a few patients reported dizziness, and two with bipolar disorder developed mania or hypomania on supplement doses. People with kidney or liver disease should take glutamine only under medical supervision.

There isn't enough safety data during pregnancy or breastfeeding to know if supplemental doses are okay, so talk with your doctor or pharmacist before using it in either situation.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (seizure drugs), check with your doctor or pharmacist before using glutamine — there's a theoretical concern it might reduce how well your medication works, though this hasn't been confirmed in humans. People with kidney or liver disease should also get the okay from their doctor before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine powder may help with sickle cell disease or recovery from surgery or critical illness, though the evidence is strongest for sickle cell disease. The main interaction concern is with seizure medications — a theoretical risk that hasn't been seen in patients.

If you have kidney or liver disease, take seizure medication, or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Powder, straight from the product label.

Brand CHK Nutrition
Barcode (UPC) 787500076321
Net contents 17.6 Oz(s); 500 Gram(s)
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 174194
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Powder by CHK Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s)
Maximum serving Sizes:
1 Scoop(s)
Servings per container
100
UPC/BARCODE
787500076321
IngredientAmount% DV
L-Glutamine, Powder5000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Contains no sugar, salt, dairy, yeast, wheat, gluten, corn, soy, preservatives, artificial colors or flavors.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take one scoop in eight ounces of water, one (1) to three (3) times daily, or as directed by a health care professional.

Storage

Store in a cool, dry place and away from direct light.

Precautions

Keep out of reach of children.

General Statements

New day. Fresh start. Better health.

Quality & potency guaranteed

FDA Statement of Identity

Dietary Supplement

General

7632

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Powder by CHK Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Powder by CHK Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

L-Glutamine, Powder

Interacts with
50 drugs
5000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine, Powder monograph & interactions
Interaction report

Glutamine Powder by CHK Nutrition Drug Interactions

Want to check YOUR meds against Glutamine Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine, Powder 50

Individual Drug Interactions

The ingredients in Glutamine Powder interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Powder interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine, Powder1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Powder, from the product label.

CHK Nutrition

See all CHK Nutrition products
Name
CHK Nutrition
Street Address
3930 E Calvary Rd
City
Duluth
State
MN
ZipCode
55803
Phone Number
877-538-8388
Pharmacist Counseling Corner

Glutamine Powder by CHK Nutrition: Common Questions

Does Glutamine Powder by CHK Nutrition interact with any medications?
Yes. Based on its ingredients, Glutamine Powder has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What side effects should I expect?
Most people don't have problems, but digestive upset — bloating, gas, nausea, diarrhea, and constipation — is the most common. Headache and muscle pain can happen too. At very high doses, dizziness has been reported. These effects usually ease if you reduce the dose.
Is it safe if I'm pregnant or breastfeeding?
There isn't enough safety data to know. Talk with your doctor or pharmacist about whether this supplement is right for you during pregnancy or while breastfeeding — they can give you personalized advice.
What does glutamine actually do in my body?
Glutamine is an amino acid your cells use to build and repair tissue. Your body makes some, but during stress, illness, or after surgery, your cells can need more than you produce on your own.
Will this help my condition?
The evidence is strong that it helps sickle cell disease. It may help with recovery after surgery, critical illness from trauma, or HIV/AIDS-related weight loss, though the evidence isn't as solid for those. If you have a specific health condition, talk with your doctor about whether this makes sense for you.
Should I avoid this if I have kidney or liver disease?
You shouldn't take supplemental glutamine without your doctor's approval if you have kidney or liver disease. These organs help clear glutamine from your body, so talk with your doctor first about whether it's safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Powder label
Go deeper

The Full Monographs Behind Glutamine Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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