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Dietary supplement

Glutamine Unflavored Ingredients & Drug Interactions

by Gaspari Nutrition

Glutamine Unflavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glutamine Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glutamine Unflavored is a dietary supplement by Gaspari Nutrition with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glutamine Unflavored by Gaspari Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Glutamine Unflavored by Gaspari Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Glutamine Unflavored by Gaspari Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is straightforward — it's pure L-Glutamine, an amino acid your body produces naturally. It's one single active ingredient in powder form with no other active ingredients or fillers listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports muscle repair and recovery.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Postoperative recovery, Wound healing, Burns, Critical illness (trauma) — and 3 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Burns.

The evidence for glutamine effectiveness depends on why you're considering it. It's rated effective for sickle cell disease.

For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is possibly effective — meaning there's some support but it's not definitive. We don't hold effectiveness data for other uses you might be thinking of.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated by healthy adults. The most common side effects when taken by mouth are gastrointestinal — belching, bloating, flatulence, constipation, diarrhea, nausea, and vomiting.

Headache and musculoskeletal pain have also been reported. A couple of patients with bipolar disorder experienced mania or hypomania at higher doses, but that's rare.

If you have kidney or liver disease, use only under medical supervision. Safety data during pregnancy is rated likely safe, but there isn't enough information to know whether supplement doses are safe while breastfeeding — talk with your doctor or pharmacist about that.

Also, because overall safety information is limited, avoid supplement doses unless your doctor recommends them.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsants (seizure medications), check with your doctor or pharmacist before using this product — glutamine might theoretically reduce how well they work, though this hasn't been seen in actual patients yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine is one to consider if you have sickle cell disease or are recovering from surgery or critical illness, though the evidence for those last two is still building. If you're on seizure medications, check with your doctor or pharmacist first — the interaction is theoretical but worth confirming.

Anyone with kidney or liver disease should talk with their healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glutamine Unflavored, straight from the product label.

Brand Gaspari Nutrition
Barcode (UPC) 646511012516
Net contents 10.58 Ounce(s); 300 Gram(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 291999
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glutamine Unflavored by Gaspari Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
60
UPC/BARCODE
646511012516
IngredientAmount% DV
L-Glutamine5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Benefits 5g Glutamine (per serving) in an easy-to-mix unflavored powder

Pure l-glutamine powder

A pure l-glutamine supplement for sports nutrition Utilizing only ultra-pure l-glutamine with no synthetic colors or fillers, Gaspari Nutrition's Glutamine is your solution in amino acid support.

Whether you are strength training or pushing yourself through long aerobic training sessions, Glutamine can help support one of your body's most abundant amino acids. Gaspari Nutrition's L-Glutamine offers you a high value product at a rock bottom price. You can rest assured, this product is made with only the highest quality in mind.

Formulation

5g Glutamine (per serving) in an easy-to-mix unflavored powder

Supports muscle repair and shortens recovery

Made in the USA from domestic and international ingredients.

Enhances natural HGH production Helps repair and build new muscle

Allergens: Contains none.

Utilizing only ultra-pure l-glutamine with no synthetic colors or fillers, Gaspari Nutrition's Glutamine is your solution in amino acid support.

General Statements

2 month supply

When combined with a proper exercise and nutrition program.

Brand IP Statement(s)

Copyright 2019 Gaspari Nutra, LLC. - All rights reserved.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

With meals Pre During Post Between meals

Suggested use: Mix one rounded scoop of Glutamine powder with 8 oz. water.

Be sure when taking Glutamine to drink at least 8 glasses of water daily for optimal results in strength and conditioning training.

Precautions

Keep out of reach of children. Check with a qualified healthcare professional before using this product if you are under 18 years of age, pregnant, nursing a baby or if you have any known or suspected medical conditions and/or are taking any prescription or OTC medications.

Check with a qualified healthcare professional before using this product if you are under 18 years of age, pregnant, nursing a baby or if you have any known or suspected medical conditions and/or are taking any prescription or OTC medications.

Do not exceed recommended dose. Not to be used as a substitute for a healthy and balanced diet and active lifestyle.

Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glutamine Unflavored by Gaspari Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glutamine Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glutamine Unflavored by Gaspari Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions
Interaction report

Glutamine Unflavored by Gaspari Nutrition Drug Interactions

Want to check YOUR meds against Glutamine Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

L-Glutamine 50

Individual Drug Interactions

The ingredients in Glutamine Unflavored interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glutamine Unflavored interact with drugs. Each result below shows which ingredient is responsible. L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glutamine Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glutamine Unflavored, from the product label.

Gaspari Nutrition

See all Gaspari Nutrition products
Name
Gaspari Nutrition
Phone Number
1.732.364.3777
Web Address
gasparinutrition.com
Pharmacist Counseling Corner

Glutamine Unflavored by Gaspari Nutrition: Common Questions

Does Glutamine Unflavored by Gaspari Nutrition interact with any medications?
Yes. Based on its ingredients, Glutamine Unflavored has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glutamine Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take while pregnant?
Yes, the safety data rates glutamine as likely safe during pregnancy. But if you're pregnant, it's still worth confirming with your doctor or pharmacist that this product makes sense for your individual situation.
What's the most common side effect?
Stomach upset — things like bloating, gas, nausea, diarrhea, or constipation are the most frequently reported. Most people tolerate it well, but if your stomach is sensitive, you might notice these.
Is it safe to breastfeed while taking this?
There isn't enough safety information to know either way. Talk with your doctor or pharmacist about whether supplement doses of glutamine are right for you while breastfeeding.
Does it really help with muscle recovery?
The data we hold rates glutamine as possibly effective for postoperative recovery and critical illness. That means there's some evidence, but it's not definitive yet — more research is needed.
What if I have kidney problems?
If you have kidney or liver disease, use glutamine only under medical supervision. Don't start it on your own — check with your doctor or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glutamine Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glutamine Unflavored label
Go deeper

The Full Monographs Behind Glutamine Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Glutamine Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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