Graviola Ingredients & Drug Interactions
by BareOrganics
What is this page for?
First and foremost: checking Graviola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Graviola is a dietary supplement by BareOrganics with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Graviola by BareOrganics
Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola by BareOrganics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Graviola by BareOrganics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: organic graviola, a tropical fruit used in traditional medicine. The liquid also includes citric acid as an inactive ingredient.
Does it work?
Couldn't assess
The evidence for graviola isn't established in our data. It's been studied for human papillomavirus (HPV), headache, male infertility, and as an insect repellent, but the research we hold shows insufficient reliable evidence to rate it for any of these uses.
How safe is it?
Well-documented data
Regular use of graviola may not be safe. The most common side effects reported in a clinical study were nausea and burning pain in the upper abdomen (epigastrium).
More serious but rare side effects include movement disorders and nerve damage (myeloneuropathy) that resemble Parkinson disease symptoms. One large study in patients with Parkinson disease found that even low amounts of graviola fruit, juice, or herbal tea containing graviola were linked to worse movement and thinking symptoms.
Graviola is rated possibly unsafe during pregnancy and best avoided while breastfeeding — not enough safety data exists to know either way. The data we hold also notes that human safety information is limited and lab studies raise concerns about possible nerve toxicity with long-term use.
Meds to double-check
Moderate interaction found
Before you start this product, check with your doctor or pharmacist if you take carbamazepine (Tegretol) — graviola may lower its blood levels and reduce how well it works to control seizures.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Graviola has very limited proven benefits and some real safety concerns, especially with regular use. If you take carbamazepine for seizures, it's a definite conversation with your doctor or pharmacist first.
Even if you don't take that drug, talk with your own healthcare provider about whether this product makes sense for you, given what we know about potential nerve damage and movement problems.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Graviola, straight from the product label.
| Brand | BareOrganics |
|---|---|
| Barcode (UPC) | 818423029641 |
| Net contents | 16 Oz(s); 473 mL |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 214948 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Graviola by BareOrganics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Carbohydrates | 2 Gram(s) | 1% |
| Total Sugars | 1 Gram(s) | -- |
| organic Graviola | 12500 mg | -- |
Other ingredients: certified organic Graviola, Citric Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Organic Graviola Juice Graviola, also known as soursop, is a green spiky fruit with a white juicy pulp that helps provide nutrition for overall health and wellness. It has been valued for hundreds of years in different tropical regions throughout the world.
Halal
Kosher
100% juice Guanabana Soursop
Formulation
Due to the pure, natural ingredients in this product, taste, color and consistency may vary.
Contains no added sugar, artificial color or preservatives.
Organic
Vegan
Gluten free
Benefits: Overall health & vitality.
Non-GMO
Super fruit juice
Certified Organic by Organic Certifiers, Inc.
General Statements
BPA free
Superfoods to nourish your life.
This container is 100% recyclable. US-ORG-043
Suggested/Recommended/Usage/Directions
Suggested use: Take 2 tablespoons (30 ml) daily or as directed by your health care professional.
Shake well before using.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
USDA Organic
Crescent M Halal OU (Kosher)
FDA Statement of Identity
Dietary Supplement
Precautions
Warning: If you are pregnant or lactating, consult a health care professional before using this product.
Keep out of reach of children.
Do not use this product if the safety seal on the bottle is broken.
Storage
Store in a cool, dry place.
Refrigerate after opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Graviola by BareOrganics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Graviola by BareOrganics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size30 mL Dosage formLiquid Servings per container16 Amounts shown are per serving.
Organic Graviola
Interacts with1 drug
Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...
Organic Graviola monograph & interactionsOther (inactive) ingredients: Certified organic Graviola, Citric Acid. These complete the product’s ingredient list but are not active constituents.
Graviola by BareOrganics Drug Interactions
HelloPharmacist Interaction Report
BareOrganics Graviola has one documented interaction: through its graviola content, it may reduce blood levels of carbamazepine (Tegretol), a seizure medication.
A rat study found that graviola extract lowered carbamazepine's peak concentration by 35% and overall exposure by 46%, which could make the drug less effective at controlling seizures.
Read the full breakdown — every affected drug type, severity by severity
If you take carbamazepine, you'll want to talk with your doctor or pharmacist before starting this product. They may need to monitor your seizure control or adjust your dose.
Use the medication checker on this page to see if any of your other drugs are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Graviola?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Graviola interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Graviola interact with drugs. Each result below shows which ingredient is responsible. organic Graviola
CarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Graviola — through 1 ingredient. Tap an ingredient for the detail:
Organic GraviolaCarbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
Read the full Organic Graviola + Carbamazepine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Graviola with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Graviola
Carbamazepine (Tegretol)
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.
Brand information
Manufacturer and brand details for Graviola, from the product label.
BareOrganics
See all BareOrganics products- Name
- BareOrganics
- Street Address
- 7702 East Doubletree Ranch Rd., Suite 300, #305
- City
- Scottsdale
- State
- AZ
- ZipCode
- 85258
- Phone Number
- 1-800-848-7910
- Web Address
- www.bareorganics.com
Graviola by BareOrganics: Common Questions
Does Graviola by BareOrganics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Graviola while pregnant or breastfeeding?
What are the most common side effects?
Does graviola work for HPV or other conditions?
Is graviola safe to take long-term?
What's in this liquid besides graviola?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Graviola is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Graviola’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Graviola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Graviola 4 references
- Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
- Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
- Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
- Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC