Havoc Ingredients & Drug Interactions
by RPN Recomp Performance Nutrition
What is this page for?
First and foremost: checking Havoc against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Havoc is a dietary supplement by RPN Recomp Performance Nutrition with 1 active ingredient. Its ingredients are commonly taken for building muscle mass, increasing strength, cutting or losing body fat.Based on those ingredients, 370 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Havoc by RPN Recomp Performance Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Havoc by RPN Recomp Performance Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Havoc by RPN Recomp Performance Nutrition
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Epistane.
- The most serious interaction on file is rated Moderate.
- For scale: 371 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Havoc, straight from the product label.
| Brand | RPN Recomp Performance Nutrition |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Dec 22, 2019 |
| DSLD ID | 210034 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Havoc by RPN Recomp Performance Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol | 10 mg | -- |
Other ingredients: Gelatin Capsule, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
The peak of performance!
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 2-3 capsules daily as directed by a physician. Do not exceed 3 capsules per day, do not exceed 4 weeks usage per 4 month period.
Precautions
Do not exceed 3 capsules per day, do not exceed 4 weeks usage per 4 month period.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Havoc by RPN Recomp Performance Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Havoc by RPN Recomp Performance Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Interacts with370 drugs
Epistane is a synthetic anabolic steroid (a methylated 'designer steroid'), not a true dietary supplement or herb, even though it has been sold as a '...
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol monograph & interactionsOther (inactive) ingredients: Gelatin Capsule, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Havoc by RPN Recomp Performance Nutrition Drug Interactions
Havoc contains a single active ingredient, and it has known interactions with 370 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Havoc?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Havoc interact with 370 drugs. Click any drug to see the details.
1 of the 1 ingredient in Havoc interact with drugs. Each result below shows which ingredient is responsible. 2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Olipudase Alfa-rpcpXenpozyme
How Olipudase Alfa-rpcp interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Olipudase Alfa-rpcp interactionOlutasidenibRezlidihia
How Olutasidenib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Olutasidenib interactionOmaveloxoloneSkyclarys
How Omaveloxolone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Omaveloxolone interactionOmbitasvir, Paritaprevir, Ritonavir, DasabuvirViekira Pak
How Ombitasvir, Paritaprevir, Ritonavir, Dasabuvir interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Ombitasvir, Paritaprevir, Ritonavir, Dasabuvir interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Ozanimod Hydrochloride interactionParacetamolPanadol
How Paracetamol interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Paracetamol interactionPazopanibVotrient
How Pazopanib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pazopanib interactionPeginterferon Beta-1aPlegridy
How Peginterferon Beta-1a interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Peginterferon Beta-1a interactionPeginterferon Alfa-2bPeg-Intron, ViraferonPeg
How Peginterferon Alfa-2b interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Peginterferon Alfa-2b interactionPemolineCylert, Cylert Chewable
How Pemoline interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pemoline interactionPexidartinib HydrochlorideTuralio
How Pexidartinib Hydrochloride interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pexidartinib Hydrochloride interactionPhenobarbital, PhenytoinDilantin with PB
How Phenobarbital, Phenytoin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Phenobarbital, Phenytoin interactionPhenytoinDi-Phen, Dilantin, Dilantin Infatabs, Dilantin injection, Dilantin Kapseals, Phenytek
How Phenytoin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Phenytoin interactionPioglitazoneActos
How Pioglitazone interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pioglitazone interactionPitavastatinNikita, Zypitamag
How Pitavastatin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pitavastatin interactionPolatuzumab Vedotin-piiqPolivy
How Polatuzumab Vedotin-piiq interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Polatuzumab Vedotin-piiq interactionPonatinibIclusig
How Ponatinib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Ponatinib interactionPralsetinibGavreto
How Pralsetinib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pralsetinib interactionPravastatin SodiumPravachol
How Pravastatin Sodium interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pravastatin Sodium interactionPretomanidPretomanid
How Pretomanid interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pretomanid interactionPropoxypheneDarvon, Davon, Margesic, Prophene-65
How Propoxyphene interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Propoxyphene interactionPropoxyphene NapsylateDarvon N
How Propoxyphene Napsylate interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Propoxyphene Napsylate interactionPropylthiouracil, PtuPropylthiouracil
How Propylthiouracil, Ptu interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Propylthiouracil, Ptu interactionPyrazinamideTebrazid
How Pyrazinamide interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Pyrazinamide interactionQuinidineCardioquin, Cin-Quin, Duraquin, Lin-Qin, Quinova, Quinaglute, Quinaglute Duratabs +2 more
How Quinidine interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Quinidine interactionRepotrectinibAugtyro
How Repotrectinib interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Repotrectinib interactionResmetiromRezdiffra
How Resmetirom interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Resmetirom interactionRezafunginRezzayo
How Rezafungin interacts with Havoc — through 1 ingredient. Tap an ingredient for the detail:
2a, 3a-epithio-17a-methyl-5a-androstan-17b-olHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Read the full 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol + Rezafungin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Havoc with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
2a, 3a-Epithio-17a-Methyl-5a-Androstan-17b-Ol
Hepatotoxic Drugs
Theoretically, concomitant use might have additive adverse hepatotoxic effects.
Epistane is an anabolic androgenic steroid, and more specifically a 17-alpha-alkylated androgen. Therefore, there is concern that epistane has hepatotoxic effects. Also, epistane is structurally similar to epitiostanol, which has been associated with hepatotixicity in a case series of four patients.
Brand information
Manufacturer and brand details for Havoc, from the product label.
RPN Recomp Performance Nutrition
See all RPN Recomp Performance Nutrition products- Name
- Recomp Performance Nutrition (RPN)
Havoc by RPN Recomp Performance Nutrition: Common Questions
Does Havoc by RPN Recomp Performance Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Havoc is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Havoc’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Havoc's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Epistane 3 references
- Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
- Rahnema CD, Crosnoe LE, Kim ED. Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem. Andrology. 2015;3(2):150-5. PubMed
- Díaz FC, Sáez-González E, Benlloch S, et al. Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis. Ann Hepatol. 2016;15(6):939-943.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC