Hawthorn Extract 150 mg Ingredients & Drug Interactions
by PhysioLogics
What is this page for?
First and foremost: checking Hawthorn Extract 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hawthorn Extract 150 mg is a dietary supplement by PhysioLogics with 1 active ingredient. Its ingredients are commonly taken for heart failure symptoms, high blood pressure, chest pain (angina).Based on those ingredients, 191 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Hawthorn Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hawthorn Extract 150 mg by PhysioLogics
Ask about any prescription or over-the-counter medication and we check it for interactions with Hawthorn Extract 150 mg by PhysioLogics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hawthorn Extract 150 mg by PhysioLogics
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Hawthorn.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
- For scale: 191 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hawthorn Extract 150 mg, straight from the product label.
| Brand | PhysioLogics |
|---|---|
| Barcode (UPC) | 716963045414 |
| Net contents | 100 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Jan 24, 2014 |
| DSLD ID | 29184 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hawthorn Extract 150 mg by PhysioLogics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Hawthorn Extract | 150 mg | -- |
Other ingredients: Maltodextrin, Gelatin, Contains <2% of
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) capsule three times daily, preferably with meals or follow the advice of your health care professional. Capsules may be opened and prepared as a tea.
FDA Disclaimer Statement
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
General
PROD. NO. 4541 B4540 05F
Precautions
TAMPER RESISTANT: Do not use if seal under cap is broken or missing.
Discontinue use and consult your doctor if any adverse reactions occur.
Not intended for use by persons under the age of 18.
KEEP OUT OF REACH OF CHILDREN.
WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Brand IP Statement(s)
(C)2012 PhysioLogics, LLC
General Statements
PRODUCT BENEFITS: The Hawthorn plant is a source of bioflavonoids and other antioxidant chemical compounds. Hawthorn is traditionally used to help promote cardiovascular health by supporting blood vessels which supply the heart with vital oxygen and nutrients.*
As a reminder, discuss the supplements and medications you take with your health care providers.
Supports a Healthy Heart*
Laboratory Tested to Guarantee Quality For Health Care Professional Use Only
Formula
Standardized to contain 2% VITEXIN
FDA Statement of Identity
Herbal Supplement
Formulation
FREE OF: artificial color, artificial flavor, artificial sweetener, preservatives, sugar, starch, milk, lactose, soy, gluten, wheat, yeast, fish, sodium.
Storage
Store at room temperature and avoid excessive heat.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hawthorn Extract 150 mg by PhysioLogics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hawthorn Extract 150 mg by PhysioLogics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Hawthorn Extract
Interacts with191 drugs
Hawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when...
Hawthorn Extract monograph & interactionsOther (inactive) ingredients: Maltodextrin, Gelatin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.
Hawthorn Extract 150 mg by PhysioLogics Drug Interactions
Hawthorn Extract 150 mg contains a single active ingredient, and it has known interactions with 191 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Hawthorn Extract 150 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hawthorn Extract 150 mg interact with 191 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hawthorn Extract 150 mg interact with drugs. Each result below shows which ingredient is responsible. Hawthorn Extract
AvanafilStendra
How Avanafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn Extract + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn Extract + Vardenafil interactionAbciximabReoPro
How Abciximab interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmlodipineNorliqva
How Amlodipine interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Hawthorn Extract 150 mg — through 1 ingredient. Tap an ingredient for the detail:
Hawthorn ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorn Extract + Amlodipine Besylate, Benazepril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hawthorn Extract 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hawthorn Extract
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Brand information
Manufacturer and brand details for Hawthorn Extract 150 mg, from the product label.
Hawthorn Extract 150 mg by PhysioLogics: Common Questions
Does Hawthorn Extract 150 mg by PhysioLogics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hawthorn Extract 150 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hawthorn Extract 150 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hawthorn Extract 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC