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Dietary supplement

High Potency Beta Glucan 200 mg Ingredients & Drug Interactions

by Solaray

Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

High Potency Beta Glucan 200 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta 1, 3/1, 6 Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of High Potency Beta Glucan 200 mg by Solaray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta-glucan (a type of soluble fiber from yeast and fungi). The 200 mg per capsule comes from beta-1,3/1,6 glucan.

The remaining inactive ingredients — rice flour, cellulose, and stearic acid — are fillers and binders that give the capsule its shape and stability.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beta-glucans's overall clinical evidence instead.

Strong

Strong clinical evidence supports Beta-glucans for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Natural Medicines).
  • On file: Dyslipidemia — rated "Likely Effective" (Natural Medicines).

Beta-glucans are rated Likely Effective for two uses: lowering cholesterol (dyslipidemia) and supporting heart health (coronary heart disease). The evidence from clinical research backs both claims.

Keep in mind that supplements work best alongside diet and lifestyle choices — they're not a substitute for your doctor's treatment plan.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. However, concentrated supplements like this one lack robust safety data, so use caution — especially if you're in a high-risk group.

During breastfeeding, there's little research on supplement doses, so talk with your doctor or pharmacist before use. In rare cases, very high doses have caused temporary liver enzyme elevation in one trial participant; this resolved on its own.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check any blood pressure medications you take — beta-glucans may lower blood pressure further. Also flag immunosuppressants (drugs that weaken your immune system), since beta-glucans can work against them.

Use the medication search tool on this page to confirm your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement may help with cholesterol and heart health if that's your goal. If you take blood pressure medicine or an immunosuppressant, check your specific medications first.

Pregnant or nursing? Talk with your pharmacist — there isn't enough safety data to be certain either way.

For most people eating a normal diet, food sources of beta-glucans are a safer bet than supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Potency Beta Glucan 200 mg, straight from the product label.

Brand Solaray
Barcode (UPC) 076280008746
Net contents 30 VegCap(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 338419
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Potency Beta Glucan 200 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 VegCap(s)
Maximum serving Sizes:
1 VegCap(s)
Servings per container
30
UPC/BARCODE
076280008746
IngredientAmount% DV
Beta 1, 3/1, 6 Glucan200 mg--

Other ingredients: Rice Flour, Cellulose, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solaray EST. 1973 A Brighter Way 1973

Formula

Beta 1,3 / 1,6 Linkages

Discussion: Beta Glucan is an insoluble fiber that has been isolated from the cell wall of baker's yeast. Solaray Beta Glucan is a quality, polybranched material that consists of beta 1,3 and 1,6 linkages.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Lab Verified

General Statements

Since 1973, we've scoured the globe for the highest-quality ingredients, connecting you with the most efficacious supplements that help you Live Brighter and embrace the moments that matter most.

100% PCR Bottles

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 1 VegCap daily with water, preferably on an empty stomach.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

High Potency Beta Glucan 200 mg by Solaray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Potency Beta Glucan 200 mg by Solaray

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 VegCap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Beta 1, 3/1, 6 Glucan

Interacts with
293 drugs
200 mg per serving Form: Yeast

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta 1, 3/1, 6 Glucan monograph & interactions

Other (inactive) ingredients: Rice Flour, Cellulose, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Potency Beta Glucan 200 mg by Solaray Drug Interactions

Want to check YOUR meds against High Potency Beta Glucan 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in High Potency Beta Glucan 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta 1, 3/1, 6 Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for High Potency Beta Glucan 200 mg, from the product label.

Solaray

See all Solaray products
Name
Solaray
City
Salt Lake City
State
UT
ZipCode
84101
Phone Number
800-538-5888
Web Address
www.solaray.com
Pharmacist Counseling Corner

High Potency Beta Glucan 200 mg by Solaray: Common Questions

Does High Potency Beta Glucan 200 mg by Solaray interact with any medications?
Yes. Based on its ingredients, High Potency Beta Glucan 200 mg has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
High Potency Beta Glucan 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is beta-glucan?
It's a type of soluble fiber found naturally in yeast, fungi, and certain grains. Your immune system and heart health may benefit from it, which is why it's used in supplements.
Will this help my cholesterol?
Beta-glucans are rated Likely Effective for lowering cholesterol. That said, supplements work best alongside a healthy diet and exercise — not instead of them.
Is it safe if I'm breastfeeding?
There's not enough research on supplement doses during breastfeeding. Talk with your pharmacist about whether this is right for you.
What are the side effects?
Beta-glucans are generally well tolerated. Topical formulas can cause mild skin reactions or contact dermatitis in some people, but oral supplements like this one rarely cause problems at normal doses.
Can I take this with my blood pressure medication?
Not without checking first. Beta-glucans may lower blood pressure on their own, so combining them with antihypertensive drugs could cause your blood pressure to drop too low. Use the medication checker below before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Potency Beta Glucan 200 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Potency Beta Glucan 200 mg label
Go deeper

The Full Monographs Behind High Potency Beta Glucan 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Potency Beta Glucan 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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