Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

HMF Maternity Ingredients & Drug Interactions

by Genestra Brands

HMF Maternity label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking HMF Maternity against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

HMF Maternity is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Consortium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against HMF Maternity by Genestra Brands

Ask about any prescription or over-the-counter medication and we check it for interactions with HMF Maternity by Genestra Brands — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of HMF Maternity by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Probiotic Consortium” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

HMF Maternity is a 4-ingredient probiotic capsule designed to support gut and immune health during pregnancy and breastfeeding. The active ingredients are four live bacterial strains: Lactobacillus paracasei, Bifidobacterium bifidum, Bifidobacterium animalis subsp. lactis, and Lactobacillus salivarius.

The capsule also contains two inactive ingredients—potato maltodextrin and hypromellose—which serve as fillers and the capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive and gut health during pregnancy.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Clostridioides difficile infection, Dysbiosis — and 2 related terms.
  • The strongest evidence on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

The two Bifidobacterium strains in this product have been studied for several uses. Both are rated Possibly Effective for irritable bowel syndrome (IBS) and respiratory tract infections.

Bifidobacterium animalis subsp. lactis is also Possibly Effective for constipation. For allergic rhinitis (hay fever) and generalized anxiety disorder, the evidence isn't established enough to rate either strain.

The effectiveness of Lactobacillus paracasei and Lactobacillus salivarius isn't covered in the data we hold.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Bifidum Bifidobacterium Animalis Subsp. Lactis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The Bifidobacterium strains are generally well tolerated in healthy people, though those with weakened immune systems should be cautious. The most common side effect reported with Bifidobacterium animalis subsp. lactis is diarrhea; bloating and gas can occur with probiotics in general but haven't been specifically reported for these strains alone.

In rare cases, probiotics have caused serious infections in critically ill patients, but this is uncommon. For pregnancy, Bifidobacterium bifidum is rated Possibly Safe; however, pregnancy and lactation safety data isn't available for the other three ingredients in this product.

Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bifidobacterium Bifidum Bifidobacterium Animalis Subsp. Lactis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bifidobacterium Animalis Subsp. Lactis, Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, separate them from this product—antibiotics can kill the live organisms in the probiotic and reduce its benefit. Lactobacillus paracasei and Lactobacillus salivarius couldn't be checked against our medication database, so confirm with your pharmacist that no other interactions exist with your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

HMF Maternity is a probiotic blend designed for pregnant and nursing people, with two strains showing Possibly Effective evidence for IBS and respiratory infections. The main caution is that antibiotics can reduce its effectiveness—you'll need to time them apart.

Since safety data for pregnancy and breastfeeding is limited for most of its ingredients, check with your doctor or pharmacist before starting it to make sure it fits your individual situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HMF Maternity, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196134700
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 233509
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HMF Maternity by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
883196134700
IngredientAmount% DV
Lactobacillus paracasei (CUL-08)0 NP--
Bifidobacterium bifidum (CUL-20)0 NP--
Bifidobacterium animalis subsp. lactis (CUL-34)0 NP--
Lactobacillus salivarius (CUL-61)0 NP--
Probiotic Consortium0 NP--

Other ingredients: Potato Maltodextrin, Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Genestra HMF (Human Microflora) Probiotics offer: Clinically studied, proprietary strains Doctor-recommended for over 20 years Research-driven, condition-specific formulas Potency guaranteed through expiration

Suggested/Recommended/Usage/Directions

Recommended Dose: Take 1 capsule daily with a meal, or as recommended by your healthcare practitioner.

Precautions

Warning: If you have an immune-compromised condition, do not use.

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

If symptoms of digestive upset occur, stop use and consult your health professional.

Keep out of the reach of children.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Storage

Store under refrigeration (below 46 degrees F).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our quality excellence Clinically studied, recommended by doctors for more than 20 years

FDA Statement of Identity

Daily Probiotic Supplement

Formulation

Supports gastrointestinal health and a healthy microflora

No artificial colors or flavors Non GMO Gluten free Soy free Dairy free No FOS

Vegan

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

HMF Maternity by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

HMF Maternity label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in HMF Maternity by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Probiotic Consortium

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Consortium monograph & interactions

Other (inactive) ingredients: Potato Maltodextrin, Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

HMF Maternity by Genestra Brands Drug Interactions

Want to check YOUR meds against HMF Maternity?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Probiotic Consortium 182

Individual Drug Interactions

The ingredients in HMF Maternity interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in HMF Maternity interact with drugs. Each result below shows which ingredient is responsible. Probiotic Consortium

Each ingredient & the kinds of drugs it affects

For each ingredient in HMF Maternity with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Consortium1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Consortium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for HMF Maternity, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

HMF Maternity by Genestra Brands: Common Questions

Does HMF Maternity by Genestra Brands interact with any medications?
Yes. Based on its ingredients, HMF Maternity has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HMF Maternity contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this probiotics product work if I'm taking antibiotics?
Not at the same time—antibiotics will kill the live bacterial strains in the product. Ask your pharmacist how to space them apart so the antibiotic can do its job and the probiotics aren't destroyed. You can take this product again once your antibiotic course is finished.
Is HMF Maternity safe to take while pregnant?
One of the strains, Bifidobacterium bifidum, is rated Possibly Safe in pregnancy. However, we don't have pregnancy safety data for the other three ingredients in the product. Talk with your doctor or pharmacist to decide if it's right for you right now.
Can I take this while breastfeeding?
We don't have specific safety data for these strains during breastfeeding on file. Discuss it with your doctor or pharmacist to see if it's appropriate for you and your baby.
What does this product actually do?
The two Bifidobacterium strains have shown Possibly Effective evidence for irritable bowel syndrome, respiratory tract infections, and (for one strain) constipation. Evidence for other uses like allergies or anxiety isn't strong enough to rate. The roles of the two Lactobacillus strains aren't documented in our data.
What side effects should I watch for?
Diarrhea, bloating, and gas are the most common complaints with these probiotics, though they're generally well tolerated. In rare cases, probiotics can cause infections, especially in people with very weak immune systems. Stop the product and contact your doctor if you develop severe abdominal pain, fever, or signs of infection.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if HMF Maternity is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HMF Maternity label
Go deeper

The Full Monographs Behind HMF Maternity’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Bifidobacterium Animalis Subsp. Lactis

Interacts with 182 drugs

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut health. It appears generally safe for most...

Read the full Bifidobacterium Animalis Subsp. Lactis monograph →
Sources

Sources & How We Checked

HMF Maternity's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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