Immune Complex Elderberry Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Immune Complex Elderberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Immune Complex Elderberry is a dietary supplement by Atlantic Naturals with 7 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 1,274 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Ginger extract, organic Garlic powder, organic Moringa powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Immune Complex Elderberry by Atlantic Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Complex Elderberry by Atlantic Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Immune Complex Elderberry by Atlantic Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Immune Complex Elderberry contains 7 active ingredients. Vitamin C supports immune function and is proven effective for vitamin C deficiency; the other ingredients—organic garlic powder, organic elderberry extract, organic astragalus extract, organic oregano powder, organic ginger extract, and organic moringa powder—are traditionally used to support immune health, though their effectiveness in this combination is not established in the data we hold.
The tablet also contains inactive ingredients (organic acacia gum, tapioca maltodextrin, silica, and an organic film coating) that help form and protect the tablet.
Does it work?
Not established
Vitamin C is effective for preventing vitamin C deficiency and possibly effective for anemia of chronic disease, atrial fibrillation, cataracts, and exercise-induced respiratory infections. The other five active ingredients lack sufficient reliable evidence in our data to rate their effectiveness for immune support or other uses—astragalus, oregano, and moringa show insufficient evidence for the conditions studied, and elderberry extract has no effectiveness data on file.
How safe is it?
Well-documented data
Vitamin C is generally well tolerated at normal dietary and supplement doses, though very high doses (above 2 grams daily) may cause abdominal cramps, diarrhea, nausea, or kidney stones in people prone to them; pregnancy safety data show it is likely safe at normal amounts but possibly unsafe at high doses, so stick to prenatal vitamin levels. Garlic powder is generally well tolerated as food but may cause stomach upset, malodorous breath, or increase bleeding risk in supplement amounts; pregnancy data suggest it is likely safe but possibly unsafe at high doses.
Astragalus is generally well tolerated short-term in healthy adults, but safety data are limited and it should be avoided in pregnancy and while breastfeeding. Oregano is safe as a food but concentrated supplements are less studied; avoid medicinal amounts in pregnancy.
Ginger is generally well tolerated at typical amounts; it is likely or possibly safe in pregnancy when used moderately. Moringa leaf appears well tolerated but long-term safety data are limited; root and bark should be avoided in pregnancy, and breastfeeding safety is not well studied.
A small number of trial participants taking moringa experienced transient diarrhea.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take estrogens (birth control or hormone therapy), blood thinners (like warfarin or other anticoagulants), antiplatelet drugs, diabetes or blood sugar medications, blood pressure drugs, thyroid medication (levothyroxine), chemotherapy or cancer drugs, lithium, or HIV protease inhibitors—these carry Moderate interactions with one or more ingredients here. Several ingredients may also affect how your liver processes other medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product may appeal to people looking for traditional immune support, though effectiveness is not established in our data for most ingredients. If you take birth control, blood thinners, thyroid medication, diabetes drugs, blood pressure medication, chemotherapy, or any HIV or immunosuppressive therapy, check your exact medications with your own doctor or pharmacist before starting—several ingredients here carry documented interactions.
Pregnant or breastfeeding women should discuss this product with their healthcare provider, as safety data vary by ingredient.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Immune Complex Elderberry, straight from the product label.
| Brand | Atlantic Naturals |
|---|---|
| Barcode (UPC) | 713152172395 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 241210 |
| Product type | Botanical With Nutrients |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Immune Complex Elderberry by Atlantic Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin C | 60 mg | 67% |
| organic Garlic powder | 150 mg | -- |
| organic Elderberry extract | 300 mg | -- |
| organic Astragalus extract | 275 mg | -- |
| organic Oregano powder | 150 mg | -- |
| organic Ginger extract | 250 mg | -- |
| organic Moringa powder | 400 mg | -- |
Other ingredients: organic Acacia Gum, Tapioca Maltodextrin, Silica, organic Film Coating
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Our Immune Complex combines super fruit Elderberry with oregano, vitamin C, garlic, astragalus, moringa and ginger. This unique combination helps to support overall health and a vibrant immune system.
With oregano, vitamin C and garlic
Suggested/Recommended/Usage/Directions
Suggested Use: Take 3 tablets daily, preferably with a meal or as directed by a healthcare professional.
General Statements
Scan me to learn more
60 Tablets per bottle
Precautions
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
Caution: Do not exceed recommended dosage.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.
Storage
Store in a cool, dry place.
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
V Vegetarian Soy free Dairy free
Formulation
Vegetarian
Soy free Dairy free
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Immune Complex Elderberry by Atlantic Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Immune Complex Elderberry by Atlantic Naturals
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin C
Interacts with207 drugs
Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...
Vitamin C monograph & interactionsOrganic Garlic powder
Interacts with989 drugs
Garlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects are usuall...
Organic Garlic powder monograph & interactionsOrganic Elderberry extract
Organic Astragalus extract
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Organic Astragalus extract monograph & interactionsOrganic Oregano powder
Interacts with208 drugs
Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...
Organic Oregano powder monograph & interactionsOrganic Ginger extract
Interacts with1,007 drugs
Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomi...
Organic Ginger extract monograph & interactionsOrganic Moringa powder
Interacts with869 drugs
Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....
Organic Moringa powder monograph & interactionsOther (inactive) ingredients: Organic Acacia Gum, Tapioca Maltodextrin, Silica, Organic Film Coating. These complete the product’s ingredient list but are not active constituents.
Immune Complex Elderberry by Atlantic Naturals Drug Interactions
HelloPharmacist Interaction Report
Immune Complex Elderberry by Atlantic Naturals contains several ingredients with documented interactions: vitamin C, garlic powder, astragalus extract, oregano powder, ginger extract, and moringa powder.
The most serious interaction is vitamin C's Moderate-severity effect on estrogens—it may increase estrogen blood levels by up to 55% in people taking birth control pills or hormone replacement therapy, potentially reducing contraceptive effectiveness or altering hormone levels.
Read the full breakdown — every affected drug type, severity by severity
Vitamin C also interacts Moderately with blood thinners like warfarin (reducing their effectiveness at higher doses), chemotherapy drugs that work by generating free radicals (alkylating agents and antitumor antibiotics), aluminum-containing compounds, thyroid medication, and several others. Garlic powder may increase bleeding risk with anticoagulants and antiplatelet drugs, lower blood pressure, affect how your body processes certain medications through the liver, and theoretically interfere with HIV protease inhibitors.
Ginger extract carries similar Moderate bleeding concerns with blood thinners and antiplatelet drugs, and may affect blood sugar control and certain heart and cancer medications.
Astragalus extract may interfere with immunosuppressive drugs (including chemotherapy), increase lithium levels, and theoretically raise low blood sugar risk. Oregano and moringa add further Moderate interactions with blood thinners and blood sugar control, plus moringa's potential effects on thyroid medication and drug-metabolizing enzymes.
We could not check organic elderberry extract—no data are on file for it.
Altogether, these interactions span 1,275 individual medications. Run your exact prescriptions through the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Immune Complex Elderberry?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Immune Complex Elderberry interact with 1,274 drugs. Click any drug to see the details.
6 of the 7 ingredients in Immune Complex Elderberry interact with drugs. Each result below shows which ingredient is responsible. organic Ginger extract organic Garlic powder organic Moringa powder organic Astragalus extract organic Oregano powder Vitamin C
AlfuzosinUroxatral
How Alfuzosin interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Alfuzosin interactionOrganic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Alfuzosin interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Alfuzosin interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Alginic Acid, Aluminum Hydroxide interactionAliskirenTekturna
How Aliskiren interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Aliskiren interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Aliskiren interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Almotriptan interactionOrganic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Almotriptan interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Immune Complex Elderberry — through 5 ingredients. Tap an ingredient for the detail:
Organic Moringa PowderAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Read the full Organic Moringa Powder + Alogliptin interactionOrganic Garlic PowderAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Garlic Powder + Alogliptin interactionOrganic Oregano PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Oregano Powder + Alogliptin interactionOrganic Ginger ExtractAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Ginger Extract + Alogliptin interactionOrganic Astragalus ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Astragalus Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Immune Complex Elderberry — through 5 ingredients. Tap an ingredient for the detail:
Organic Astragalus ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Astragalus Extract + Alogliptin, Metformin interactionOrganic Ginger ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Ginger Extract + Alogliptin, Metformin interactionOrganic Oregano PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Oregano Powder + Alogliptin, Metformin interactionOrganic Garlic PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Garlic Powder + Alogliptin, Metformin interactionOrganic Moringa PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Read the full Organic Moringa Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Immune Complex Elderberry — through 5 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Garlic Powder + Alogliptin, Pioglitazone interactionOrganic Oregano PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Oregano Powder + Alogliptin, Pioglitazone interactionOrganic Ginger ExtractAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Ginger Extract + Alogliptin, Pioglitazone interactionOrganic Astragalus ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Astragalus Extract + Alogliptin, Pioglitazone interactionOrganic Moringa PowderAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Read the full Organic Moringa Powder + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Alpelisib interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Alpelisib interactionOrganic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Alprazolam interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Alprazolam interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Garlic Powder + Alteplase, Tpa interactionOrganic Ginger ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Ginger Extract + Alteplase, Tpa interactionOrganic Oregano PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Oregano Powder + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAlkylating Agents Moderate
Interaction Summary
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
Read the full Vitamin C + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Immune Complex Elderberry — through 4 ingredients. Tap an ingredient for the detail:
Vitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOrganic Oregano PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Oregano Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOrganic Ginger ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Ginger Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOrganic Garlic PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Garlic Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Immune Complex Elderberry — through 4 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Garlic Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionOrganic Oregano PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Organic Oregano Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionOrganic Ginger ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Ginger Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionVitamin CAspirin, Aluminum Moderate
Interaction Summary
Acidification of the urine by vitamin C might increase aspirin levels.
Read the full Vitamin C + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Vitamin CAluminum Moderate
Interaction Summary
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Read the full Vitamin C + Aluminum, Magnesium Hydroxide (otc Drug) interactionAlvimopanEntereg
How Alvimopan interacts with Immune Complex Elderberry — through 2 ingredients. Tap an ingredient for the detail:
Organic Ginger ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
Read the full Organic Ginger Extract + Alvimopan interactionOrganic Moringa PowderP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
Read the full Organic Moringa Powder + Alvimopan interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Moringa PowderP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
Read the full Organic Moringa Powder + Ambrisentan interactionOrganic Garlic PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Organic Garlic Powder + Ambrisentan interactionOrganic Ginger ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
Read the full Organic Ginger Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Organic Garlic PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Organic Garlic Powder + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Immune Complex Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Organic Garlic PowderAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Organic Garlic Powder + Amiloride, Hydrochlorothiazide interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Amiodarone interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Amiodarone interactionOrganic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Amitriptyline interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Amitriptyline interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Moringa PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Organic Moringa Powder + Amitriptyline, Chlordiazepoxide interactionOrganic Ginger ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger Extract + Amitriptyline, Chlordiazepoxide interactionOrganic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Garlic PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Organic Garlic Powder + Amitriptyline, Perphenazine interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Amitriptyline, Perphenazine interactionOrganic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Immune Complex Elderberry — through 3 ingredients. Tap an ingredient for the detail:
Organic Ginger ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Calcium Channel Blockers Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger Extract + Amlodipine interactionOrganic Garlic PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Organic Garlic Powder + Amlodipine interactionOrganic Moringa PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Organic Moringa Powder + Amlodipine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Immune Complex Elderberry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Ginger extract
Anticoagulant/Antiplatelet Drugs
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.
Losartan (Cozaar)
Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.
Nifedipine (Procardia)
Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.
P-Glycoprotein Substrates
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Phenprocoumon (Marcoumar, Others)
Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.
Warfarin (Coumadin)
Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.
Calcium Channel Blockers
Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.
Cyclosporine (Neoral, Sandimmune)
Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.
Metronidazole (Flagyl)
Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.
organic Garlic powder
Anticoagulant/Antiplatelet Drugs
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Raw garlic and a variety of garlic extracts have antiplatelet activity and can increase prothrombin time.
Antidiabetes Drugs
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research suggests that garlic and garlic extract lower blood glucose levels in healthy and diabetic individuals.
Antihypertensive Drugs
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
In human research, both garlic and garlic extracts have blood pressure-lowering effects.
Atazanavir (Reyataz)
Theoretically, garlic might decrease levels and effects of atazanavir.
In a case report, a patient consuming six stir-fried garlic cloves three times weekly developed suboptimal atazanavir levels and increases in HIV viral load. While the exact cause of this interaction is unclear, there is speculation that garlic might decrease the intestinal absorption of atazanavir or increase its metabolism by inducing cytochrome P450 3A4 (CYP3A4). Until more is known, advise patients not to consume large amounts of garlic while taking atazanavir.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Garlic might increase levels of drugs metabolized by CYP2E1.
Clinical research suggests garlic oil can inhibit the activity of CYP2E1 by 39%. Use garlic oil cautiously in patients taking drugs metabolized by these enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4. This may increase or decrease levels of drugs metabolized by CYP3A4.
Some human research suggests that garlic may induce INTESTINAL CYP3A4, reducing levels of drugs metabolized by this enzyme. This is primarily based on a study showing that taking a specific allicin-containing garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces saquinavir levels by approximately 50%. It is speculated that the allicin constituent induced CYP3A4 in the gut mucosa. Another study shows that giving docetaxel intravenously, bypassing the CYP3A4 enzymes in the gut mucosa, along with the same specific garlic product for 12 consecutive days, does not affect docetaxel levels. Conversely, there is concern that garlic may inhibit HEPATIC CYP3A4. In a single case report, increased tacrolimus levels and liver injury occurred in a liver transplant patient after taking a specific garlic supplement (Garlicin Cardio, Nature's Way) at up to three times the manufacturer recommended dose for 7 days. Several other studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin.
Isoniazid
Theoretically, garlic might decrease levels of isoniazid.
Animal research suggests that an aqueous extract of garlic reduces isoniazid levels by about 65%. Garlic reduced the maximum concentration (Cmax) and area under the curve (AUC), but not the half-life, of isoniazid. This suggests that garlic extract might inhibit isoniazid absorption across the intestinal mucosa; however, the exact mechanism of this potential interaction is not known.
Protease Inhibitors (Pis)
Theoretically, garlic products containing allicin might decrease levels of PIs.
Protease inhibitors are metabolized by cytochrome P450 3A4 (CYP3A4) isoenzymes. There is concern that garlic products containing allicin might induce intestinal CYP3A4, reducing plasma levels of protease inhibitors. This is primarily based on a study showing that taking a specific garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces levels of saquinavir, a PI, by approximately 50%. It is speculated that the allicin constituent induce CYP3A4 in the gut mucosa. Several studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin.
Saquinavir (Fortovase, Invirase)
Theoretically, garlic containing allicin might decrease levels of saquinavir.
Saquinavir is a substrate of cytochrome P450 3A4 (CYP3A4) isoenzymes. There is concern that garlic products containing allicin might induce intestinal CYP3A4 and cause subtherapeutic levels of saquinavir. This is primarily based on a pharmacokinetic study showing that taking a specific garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces saquinavir levels by approximately 50%. It is speculated that the allicin constituent induces CYP3A4 in the gut mucosa. Several pharmacokinetic studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin. Until more is known about this potential interaction, use garlic containing allicin cautiously in patients taking saquinavir.
Sofosbuvir (Sovaldi)
Theoretically, taking garlic with sofosbuvir might decrease its effectiveness.
Animal research in rats shows that giving aged garlic extract 120 mg/kg orally daily for 14 days decreases the area under the concentration time curve (AUC) after a single sofosbuvir dose of 40 mg/kg by 36%, increases the clearance by 63%, and decreases the plasma concentrations at 1 and 8 hours by 35% and 58%, respectively. This interaction is hypothesized to be due to induction of intestinal P-glycoprotein expression by garlic.
Tacrolimus (Prograf)
Theoretically, garlic might increase levels of tacrolimus.
In one case report, a liver transplant patient taking tacrolimus experienced increased tacrolimus levels and liver injury after taking a specific garlic supplement (Garlicin Cardio, Nature's Way) at up to three times the manufacturer recommended dose for 7 days. It is speculated that garlic inhibited hepatic cytochrome P450 3A4 (CYP3A4), which increased plasma levels of tacrolimus.
Warfarin (Coumadin)
Theoretically, garlic might increase the risk of bleeding with warfarin.
Raw garlic and a variety of garlic extracts have antiplatelet activity and can increase prothrombin time. In addition, there is a report of two patients who experienced an increase in a previously stabilized international normalized ratio (INR) with concomitant garlic and warfarin use. However, this report has been subsequently debated due to limited clinical information. Other clinical studies have not identified an effect of garlic on INR, warfarin pharmacokinetics, or bleeding risk. More evidence is needed to determine the safety of using garlic with warfarin.
organic Moringa powder
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
Levothyroxine (Synthroid, Others)
Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.
P-Glycoprotein Substrates
Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.
Antidiabetes Drugs
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.
Nevirapine (Viramune)
Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
organic Astragalus extract
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
organic Oregano powder
Anticoagulant/Antiplatelet Drugs
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.
Antidiabetes Drugs
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.
Vitamin C
Alkylating Agents
Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Aluminum
Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.
Antitumor Antibiotics
Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.
Estrogens
Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.
Fluphenazine (Prolixin)
Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.
Indinavir (Crixivan)
Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.
Levothyroxine (Synthroid, Others)
Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.
Warfarin (Coumadin)
High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.
Acetaminophen (Tylenol, Others)
High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.
Aspirin
Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.
Choline Magnesium Trisalicylate (Trilisate)
Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Niacin
Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.
Salsalate (Disalcid)
Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.
Brand information
Manufacturer and brand details for Immune Complex Elderberry, from the product label.
Atlantic Naturals
See all Atlantic Naturals products- Name
- Atlantic Naturals
- Street Address
- 4264 N State Rd 7
- City
- Ft Lauderdale
- State
- FL
- ZipCode
- 33319
- Phone Number
- 561 948 1503
- Web Address
- atlanticnaturals.com
Immune Complex Elderberry by Atlantic Naturals: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Immune Complex Elderberry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin C
Interacts with 207 drugsVitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...
Read the full Vitamin C monograph → Herb & supplement monographGarlic
Interacts with 989 drugsGarlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects are usually small. It is generally safe in food am...
Read the full Garlic monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph → Herb & supplement monographOregano
Interacts with 208 drugsOregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...
Read the full Oregano monograph → Herb & supplement monographGinger
Interacts with 1,007 drugsGinger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...
Read the full Ginger monograph → Herb & supplement monographMoringa
Interacts with 869 drugsMoringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common. Early research hints at possible benefi...
Read the full Moringa monograph →Sources & How We Checked
Immune Complex Elderberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 317 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin C 51 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
- Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
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