Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Immune Health Support Ingredients & Drug Interactions

by GNC Preventive Nutrition

Immune Health Support label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Immune Health Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Immune Health Support is a dietary supplement by GNC Preventive Nutrition with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wellmune Baker's Yeast Beta Glucans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Immune Health Support by GNC Preventive Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Health Support by GNC Preventive Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Immune Health Support by GNC Preventive Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Wellmune Baker's Yeast Beta Glucans. Beta-glucans are compounds derived from yeast that your immune system can recognize and respond to.

The capsule also contains several inactive ingredients—cellulose, vegetable cellulose capsule material, silicon dioxide, magnesium stearate, and titanium dioxide—which help form and stabilize the supplement.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Enhances daily immune defense with clinically proven dose.
  • We looked for evidence on: Exercise-induced respiratory infections, Lower respiratory tract infections, Critical illness (trauma), Wound healing, Immune function, Upper respiratory tract infections — and 1 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections, Wound healing, Critical illness (trauma).

According to the research we have on file, Wellmune Baker's Yeast Beta Glucans is likely effective for two heart-related conditions: dyslipidemia (abnormal cholesterol and fat levels in the blood) and coronary heart disease. The evidence suggests it may help with cholesterol and heart health, though this product is labeled as a support supplement, not a treatment.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. However, concentrated supplements like this one lack extensive safety data, so caution is advised.

When taken orally in supplement form, adverse effects are uncommon. One child in a clinical trial developed temporary elevations in liver enzymes after taking a very high dose of beta-glucans, though this reversed on its own.

There isn't enough research on supplement doses of beta-glucans during breastfeeding to know whether it's safe, so talk with your doctor or pharmacist if you're nursing and considering this product. Pregnancy safety data isn't on file for this ingredient—check with your healthcare provider about using it if you're pregnant or planning to become pregnant.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on antihypertensive drugs (blood pressure medications) or immunosuppressants. Both carry Moderate-severity interactions with beta-glucans in this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is worth considering if you're interested in immune and heart health support and you don't take blood pressure medications or immunosuppressant drugs. If you do take either of those, or any other prescription medication, check with your doctor or pharmacist first—the interaction profile is significant enough to warrant a quick conversation before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune Health Support, straight from the product label.

Brand GNC Preventive Nutrition
Barcode (UPC) 048107161347
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2016
DSLD ID 67168
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune Health Support by GNC Preventive Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
048107161347
IngredientAmount% DV
Wellmune Baker's Yeast Beta Glucans250 mg--

Other ingredients: Cellulose, Vegetable Cellulose Capsule, Silicon Dioxide, Magnesium Stearate, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

This product is endorsed by the physicians on the GNC Medical Advisory Board.

New

Physician formulated nutrition solutions - Enhances daily immune defense with clinically proven dose

Physician endorsed

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Powered by Wellmune

Wellmune Wellmune is a registered trademark of Biothera Inc.

FDA Statement of Identity

Dietary Supplement

General

CODE 619312 FQG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily.

Formulation

No Sugar, no Preservatives, no Corn, no Starch, Sodium free, no Soy, no Artificial Colors, no Wheat, no Dairy, no Artificial Flavors, Gluten free.

Seals/Symbols

Gf Gluten free

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Immune Health Support by GNC Preventive Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Immune Health Support label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Immune Health Support by GNC Preventive Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Wellmune Baker's Yeast Beta Glucans

Interacts with
293 drugs
250 mg per serving Form: Yeast Beta 1,3/1,6 glucan

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Wellmune Baker's Yeast Beta Glucans monograph & interactions

Other (inactive) ingredients: Cellulose, Vegetable Cellulose Capsule, Silicon Dioxide, Magnesium Stearate, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune Health Support by GNC Preventive Nutrition Drug Interactions

Want to check YOUR meds against Immune Health Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Wellmune Baker's Yeast Beta Glucans 293

Individual Drug Interactions

The ingredients in Immune Health Support interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Immune Health Support interact with drugs. Each result below shows which ingredient is responsible. Wellmune Baker's Yeast Beta Glucans

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune Health Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wellmune Baker's Yeast Beta Glucans2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Wellmune Baker's Yeast Beta Glucans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Immune Health Support, from the product label.

GNC Preventive Nutrition

See all GNC Preventive Nutrition products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Immune Health Support by GNC Preventive Nutrition: Common Questions

Does Immune Health Support by GNC Preventive Nutrition interact with any medications?
Yes. Based on its ingredients, Immune Health Support has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune Health Support contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is beta-glucans and what does it do?
Beta-glucans are compounds from yeast that your immune system recognizes. This ingredient is included to support immune health and may also help with heart health and cholesterol levels based on clinical research.
Is this safe to take long-term?
Beta-glucans from food are well tolerated, but concentrated supplements like this one lack long-term safety data. Your doctor or pharmacist can advise whether long-term use is right for you.
Can I take this while pregnant or breastfeeding?
There isn't enough research data to know whether this supplement dose is safe during pregnancy. During breastfeeding, the safety data is also limited, so caution is advised. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.
What are the side effects?
Oral beta-glucans are generally well tolerated with few reported side effects. One case reported temporary liver enzyme elevations in a child at very high doses, which reversed on its own.
Will this help my cholesterol or heart health?
The research we have on file shows beta-glucans are likely effective for dyslipidemia (abnormal cholesterol and fat levels) and coronary heart disease support. This product is labeled as a support supplement, not a treatment for these conditions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Immune Health Support is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune Health Support label
Go deeper

The Full Monographs Behind Immune Health Support’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Immune Health Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP&reg; for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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