Ionic Chromium Ingredients & Drug Interactions
by Good State
What is this page for?
First and foremost: checking Ionic Chromium against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ionic Chromium is a dietary supplement by Good State with 1 active ingredient. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ionic Chromium by Good State
Ask about any prescription or over-the-counter medication and we check it for interactions with Ionic Chromium by Good State — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Ionic Chromium by Good State
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: chromium in liquid ionic form. Chromium is a mineral that plays a role in how your body manages blood sugar and uses nutrients.
The liquid also includes inactive ingredients—water, fulvic acid, and sorbic acid (a preservative)—that serve as the base.
Does it work?
Strong evidence
Chromium is likely effective for chromium deficiency, which is rare in people eating a varied diet. For type 2 diabetes, the evidence suggests it's possibly effective—some research shows it may help lower blood glucose, especially in people whose diabetes is not well controlled.
For prediabetes, schizophrenia, and high blood pressure, the evidence we have rates chromium as possibly ineffective for these uses.
How safe is it?
Well-documented data
Chromium is generally well tolerated at typical supplement doses. The most common side effects are mild—gastrointestinal upset, headaches, insomnia, and mood changes.
Rare serious effects like kidney or liver damage and blood cell problems have been reported, though they're uncommon. For pregnancy and breastfeeding: small amounts from food or a prenatal vitamin are considered likely safe, but extra supplement doses should be avoided unless your doctor advises otherwise.
The safety data on higher doses is limited, so talk with your doctor or pharmacist before taking this if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take insulin or antidiabetes drugs (moderate risk of low blood sugar), levothyroxine or other thyroid medication (moderate risk of decreased absorption), NSAIDs, or aspirin (minor risk of increased chromium levels). These interactions may require dose adjustments or timing changes.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Ionic Chromium may help if you have a chromium deficiency or type 2 diabetes that isn't well controlled, though the evidence for diabetes is modest. If you take insulin, diabetes medication, thyroid medication (levothyroxine), NSAIDs, or aspirin, check with your doctor or pharmacist before starting—chromium can change how these work.
Talk it over with your own healthcare provider to see if it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ionic Chromium, straight from the product label.
| Brand | Good State |
|---|---|
| Barcode (UPC) | 857515003251 |
| Net contents | 8.1 fl. Oz.; 240 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 276941 |
| Product type | Mineral |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ionic Chromium by Good State, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Chromium | 600 mcg | 1720% |
Other ingredients: reverse osmosis Water, Chromium, Catalyst, Fulvic Acid, non-GMO Sorbic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Chromium is one of the best supporters for regulating blood sugar levels and maintaining a healthy heart. Due to lack of minerals in our solid and water, the average American is chromium deficient.
Ionic mineral
Formulation
Good State ionic minerals have been known for their high bioavailability, while other supplements can be extremely low.
Contains no sugars, soy, GMO, dairy, gluten, starch, artificial flavors, colors, or animal by-products and is hypoallergenic.
Contains no sugars, soy, GMO, dairy, gluten, starch, artificial flavors, colors, or animal by-products and is hypoallergenic
Suitable for vegans.
Good State is proud to follow Good Manufacturing Practices (GMP)
High bioavailability
General Statements
Note: Chromium benefits and/or deficiency symptoms are generic for mineral. No product claims are being made or implied. Research is ongoing.
100% satisfaction guaranteed
Professional grade
Text support +1-215-608-1124
Seals/Symbols
Made in the USA
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Give your body what it needs! Good State Health Solutions
Good State's nano ionic supplements
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults: Take 2.5 mL (1/2 tsp) in 6-8 oz of water or juice once per day. Children under 4: Please consult a physician. Use more if needed or as recommended by your healthcare professional. Do not take on an empty stomach. Must be diluted. Do not take without water or juice
Precautions
Children under 4: Please consult a physician.
Do not take on an empty stomach. Must be diluted. Do not take without water or juice.
Caution: Keep out of reach of children.
Always speak with your physician before using any dietary supplement. Do not use if tamper evident seal is broken or missing.
Storage
For freshness after opening, store in a cool, dark place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ionic Chromium by Good State label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ionic Chromium by Good State
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2.5 mL Dosage formLiquid Servings per container96 Amounts shown are per serving.
Chromium
Interacts with178 drugs
Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...
Chromium monograph & interactionsOther (inactive) ingredients: Reverse osmosis Water, Chromium, Catalyst, Fulvic Acid, Non-GMO Sorbic Acid. These complete the product’s ingredient list but are not active constituents.
Ionic Chromium by Good State Drug Interactions
HelloPharmacist Interaction Report
Ionic Chromium by Good State interacts with several medication types.
The most serious concern is with insulin and antidiabetes drugs—chromium may increase your body's sensitivity to these medications and raise the risk of low blood sugar (hypoglycemia). If you take insulin or diabetes medication, your blood sugar levels need monitoring, and your doses may need adjustment.
Read the full breakdown — every affected drug type, severity by severity
Chromium can also interfere with how your body absorbs levothyroxine (a thyroid medication)—research shows it may lower levothyroxine levels by around 17%. If you take thyroid medication, separate doses by several hours.
Nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin may increase how much chromium your body absorbs, though the clinical significance isn't fully clear.
Altogether, these interactions span 178 individual medications. Use the medication checker below to look up your exact drugs before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ionic Chromium?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ionic Chromium interact with 178 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ionic Chromium interact with drugs. Each result below shows which ingredient is responsible. Chromium
Aspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids), Aspirin Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Aspirin, Pentazocine interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Bromfenac Sodium interactionBupivacaine, MeloxicamZynrelef Kit
How Bupivacaine, Meloxicam interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Bupivacaine, Meloxicam interactionCelecoxibCelebrex, Elyxyb
How Celecoxib interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Celecoxib interactionCelecoxib, TramadolSeglentis
How Celecoxib, Tramadol interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Celecoxib, Tramadol interactionDiclofenacZorvolex
How Diclofenac interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diclofenac interactionDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
How Diclofenac Potassium interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diclofenac Potassium interactionDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
How Diclofenac Sodium interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diclofenac Sodium interactionDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
How Diclofenac Sodium, Misoprostol interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
How Diclofenac Epolamine interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diclofenac Epolamine interactionDiflunisalDolobid
How Diflunisal interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diflunisal interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
How Diphenhydramine Hydrochloride, Naproxen Sodium interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Diphenhydramine Hydrochloride, Naproxen Sodium interactionEsomeprazole, NaproxenVimovo
How Esomeprazole, Naproxen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Esomeprazole, Naproxen interactionEtodolacEtodolac, Lodine, Lodine XL, Ultradol
How Etodolac interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Etodolac interactionEtoricoxibArcoxia
How Etoricoxib interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Etoricoxib interactionFamotidine, IbuprofenDuexis
How Famotidine, Ibuprofen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Famotidine, Ibuprofen interactionFenoprofen CalciumNalfon
How Fenoprofen Calcium interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Fenoprofen Calcium interactionFloctafenineIdarac
How Floctafenine interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Floctafenine interactionFlurbiprofenAnsaid, Flurbiprofen, Flurprofen, Froben, Froben SR, Ocufen
How Flurbiprofen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Flurbiprofen interactionHydrocodone, IbuprofenVicoprofen
How Hydrocodone, Ibuprofen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Hydrocodone, Ibuprofen interactionIbuprofenAdvil, Arthrofen, Brufen, Brufen Retard, Calodor, Calprofen +14 more
How Ibuprofen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Ibuprofen interactionIbuprofen LysineNeoProfen
How Ibuprofen Lysine interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Ibuprofen Lysine interactionIbuprofen, AcetaminophenAdvil Dual Action
How Ibuprofen, Acetaminophen interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Ibuprofen, Acetaminophen interactionIbuprofen, HydrocodoneIbucodone
How Ibuprofen, Hydrocodone interacts with Ionic Chromium — through 1 ingredient. Tap an ingredient for the detail:
ChromiumNonsteroidal Anti-inflammatory Drugs (nsaids) Minor
Interaction Summary
NSAIDs might increase chromium levels in the body.
Read the full Chromium + Ibuprofen, Hydrocodone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ionic Chromium with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Chromium
Antidiabetes Drugs
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.
Insulin
Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,
Levothyroxine (Synthroid, Others)
Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.
Aspirin
Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.
Brand information
Manufacturer and brand details for Ionic Chromium, from the product label.
Good State
- Name
- GoodState, Inc.
- Street Address
- 575 Virginia Drive, Suite C
- City
- Fort Washington
- State
- PA
- ZipCode
- 19034
- Phone Number
- 1-866-227-6097
- Web Address
- www.GoodState.com
Ionic Chromium by Good State: Common Questions
Does Ionic Chromium by Good State interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this lower my blood sugar too much if I'm already on diabetes medication?
Can I take this with my thyroid medication?
Is it safe to take while pregnant?
What are the most common side effects?
Does this product actually work for prediabetes?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ionic Chromium is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ionic Chromium’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ionic Chromium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 53 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chromium 53 references
- Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
- Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
- Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
- Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
- Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
- Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
- McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
- Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
- Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
- Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
- Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
- Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
- Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
- Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
- Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
- Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
- Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
- John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
- Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
- Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
- Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
- Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
- Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
- Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
- Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
- Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
- Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
- Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
- Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
- Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
- Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
- Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
- Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
- Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
- Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
- Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
- Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
- Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
- De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
- Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
- Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
- Liu Y, Cotillard A, Vatier C, et al. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial. PLoS One.
- Jamilian M, Asemi Z. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab. 2015;67(1):42-8. PubMed
- Guimarães MM, Carvalho AC, Silva MS. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry. J Trace Elem Med Bi PubMed
- Paiva AN, Lima JG, Medeiros AC, et al. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015;32:66-72. PubMed
- Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J. 2015;14:14. PubMed
- Jamilian M, Zadeh Modarres S, Amiri Siavashani M, et al. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilizati
- Alinaghi F, Thyssen JP, Zachariae C, Johansen JD. No immediate effect of regulatory reduction of chromium in leather among adult patients with chromium allergy. Contact Dermatitis 2021;85(5):514-522. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC