Interactions on record — worth a quick check against your medications. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Kids Probiotic 3 Billion Berry-licious Ingredients & Drug Interactions

by Renew Life Ultimate Flora

Kids Probiotic 3 Billion Berry-licious label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kids Probiotic 3 Billion Berry-licious against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kids Probiotic 3 Billion Berry-licious is a dietary supplement by Renew Life Ultimate Flora with 7 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Bacillus coagulans, Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora

Ask about any prescription or over-the-counter medication and we check it for interactions with Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Kids Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 6 active ingredients, all of them beneficial bacteria (probiotics): Lactobacillus salivarius, Lactobacillus plantarum, Lactobacillus acidophilus, Bacillus coagulans, Bifidobacterium animalis lactis, and Bifidobacterium breve. These are live microorganisms designed to support digestive and gut health in children.

The inactive ingredients include sweetener (xylitol), natural fruit juice, natural fruit flavors, citric acid, malic acid, and several processing aids like stearic acid, silica, magnesium stearate, and monk fruit extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive balance and healthy digestion for kids.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Diarrhea, Dyspepsia, Flatulence — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation, Irritable bowel syndrome (IBS).

The evidence for these probiotics varies by condition. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, and bacterial vaginosis.

Bacillus coagulans is possibly effective for constipation and IBS. Bifidobacterium breve's effectiveness remains largely unproven or insufficient evidence for the conditions studied.

For most other conditions in the data we hold, the evidence isn't strong enough to make a claim. Talk with your child's doctor about what you're hoping this probiotic will help with—they can tell you whether it's the right fit for your child's situation.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Bacillus Coagulans Bifidobacterium Breve

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus and Bacillus coagulans are generally well tolerated in healthy children, though Bacillus coagulans safety data are limited and vary by product quality. Bifidobacterium breve is generally well tolerated in healthy people but should be used with caution in very ill or immunocompromised children.

Uncommon gastrointestinal side effects reported with probiotics include bloating, flatulence, abdominal pain, diarrhea, and burping. In rare cases, live probiotic organisms have caused serious bloodstream infections (bacteremia or sepsis), mostly in critically ill, premature, or severely immunocompromised patients; healthy children with normal immune systems face a much lower risk.

Pregnancy and lactation safety data for most of these ingredients aren't on file; Lactobacillus acidophilus is rated possibly safe in pregnancy, but you should discuss probiotic use with your child's pediatrician before starting.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Bacillus Coagulans Bifidobacterium Breve

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bacillus Coagulans, Bifidobacterium Breve.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If your child takes antibiotic drugs, the probiotic may become less effective if given at the same time. Talk with your pharmacist or doctor about spacing doses apart—usually a few hours between the antibiotic and the probiotic is enough to protect the beneficial bacteria.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This kids' probiotic combines several bacterial strains with possible benefits for digestive issues like IBS and constipation, though the evidence is mixed across the board. The main caution is timing it right if your child is on antibiotics.

Before starting, check with your child's pediatrician or pharmacist—especially if your child has a weakened immune system or is critically ill—to make sure it's appropriate for them.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kids Probiotic 3 Billion Berry-licious, straight from the product label.

Brand Renew Life Ultimate Flora
Barcode (UPC) 631257120250
Net contents 90 Chewable Tablet(s)
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 203528
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Dairy Free, Sugar Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
631257120250
IngredientAmount% DV
Calories3 Calorie(s)--
Total Carbohydrates0.6 Gram(s)1%
Sugar0 Gram(s)--
Sugar Alcohol0.6 Gram(s)--
Lactobacillus salivarius0 NP--
Lactobacillus plantarum0 NP--
Lactobacillus acidophilus0 NP--
Bacillus coagulans0 NP--
Bifidobacterium animalis lactis0 NP--
Bifidobacterium breve0 NP--
Kids Probiotic Blend0 NP--

Other ingredients: Xylitol, Stearic Acid, natural Fruit juice, natural Fruit flavors, Citric Acid, Malic Acid, Silica, Magnesium Stearate, Monk Fruit extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Healthy kids = Happy kids Keep your child's tummy in tip-top spirits every day. When taken regularly, Ultimate Flora Probiotics support digestive balance to help kids feel healthier and happier - whether at school or at play. Safe & effective Our kid friendly formulas work hard to provide more of the good-for-you bacteria that occur in a natural healthy gut.

3 Billion live cultures guaranteed 6 Probiotic strains

Ultimate Flora 3 Billion Kids Probiotic is jam-packed with great berry-licious taste. Made with 6 specially selected strains to ease occasional tummy trouble and support digestive health. Naturally sweetened with tooth-friendly Xylitol.

General Statements

Multi-strain benefits Supporting good balance among all the diverse microbes in the digestive tract is key to your child's well-being. But the environment, poor diet and specific medications can put their gut in a rut. Ultimate Flora Probiotics are made with multiple, scientifically studied strains to support digestive balance and harmony.

Helps reduce occasional digestive upsets Supports everyday optimal health

Quality, purity and potency guaranteed through expiration.

Digestive wellness, naturally At Renew Life, we believe a healthy gut is a happy gut. For nearly two decades, we have pioneered superior-quality digestive care supplements to help adults and kids alike achieve optimal health from the inside out.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Tamper evident: Do not use if safety seal on bottle is broken or missing.

Keep out of reach of children. Use only for children 2 years and older.

Consult your healthcare professional before using this or any product if your child is taking medication or have a medical condition.

Formulation

Sugar, dairy & gluten free

Gluten free Dairy free Soy free

No artificial sweeteners, flavors or colors.

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Directions: Children 2 years and older, chew one (1) tablet daily.

Everyday Kids Probiotic

Storage

Store at 77(0)F (25(0)C) or below. Best if refrigerated.

Brand IP Statement(s)

2017 Made in USA of global ingredients.

General

#1570004 010917 6700002A

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kids Probiotic 3 Billion Berry-licious label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Kids Probiotic Blend

0 NP per serving

Other (inactive) ingredients: Xylitol, Stearic Acid, Natural Fruit juice, Natural Fruit flavors, Citric Acid, Malic Acid, Silica, Magnesium Stearate, Monk Fruit extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora Drug Interactions

Want to check YOUR meds against Kids Probiotic 3 Billion Berry-licious?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182
Bacillus coagulans 182
Bifidobacterium breve 182

Individual Drug Interactions

The ingredients in Kids Probiotic 3 Billion Berry-licious interact with 182 drugs. Click any drug to see the details.

3 of the 7 ingredients in Kids Probiotic 3 Billion Berry-licious interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Bacillus coagulans Bifidobacterium breve

Each ingredient & the kinds of drugs it affects

For each ingredient in Kids Probiotic 3 Billion Berry-licious with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions

Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans full monograph & interactions

Bifidobacterium breve1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium breve full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kids Probiotic 3 Billion Berry-licious, from the product label.

Renew Life Ultimate Flora

See all Renew Life Ultimate Flora products
Name
Renew Life Formulas, Inc.
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.renewlife.com
Pharmacist Counseling Corner

Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora: Common Questions

Does Kids Probiotic 3 Billion Berry-licious by Renew Life Ultimate Flora interact with any medications?
Yes. Based on its ingredients, Kids Probiotic 3 Billion Berry-licious has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kids Probiotic 3 Billion Berry-licious contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this probiotic to my child while they're on antibiotics?
Taking them at the exact same time may reduce how well the probiotic works, since antibiotics can kill the live bacteria in it. Ask your pharmacist or doctor about spacing the doses—usually separating them by a few hours is enough to protect the probiotic's organisms.
What are the live bacteria in this product supposed to do?
These are beneficial bacteria meant to support digestive and gut health. Lactobacillus acidophilus and Bacillus coagulans are possibly effective for irritable bowel syndrome and antibiotic-associated diarrhea, and Bacillus coagulans may help with constipation. The other strains have less-proven or insufficient evidence for specific conditions.
What side effects might my child experience?
Uncommon gastrointestinal side effects include bloating, flatulence, abdominal pain, and diarrhea. In very rare cases, live probiotic organisms have caused serious infections, but this happens almost exclusively in critically ill, premature, or severely immunocompromised patients—healthy children face a much lower risk.
Is this product safe for my healthy child to take long-term?
Yes, these probiotics are generally well tolerated in healthy children. That said, safety data vary by ingredient and product quality, so it's worth mentioning to your pediatrician that your child is taking it.
Can I use this if my child has a compromised immune system?
You should talk with your child's doctor first. Live probiotic products carry a higher risk of serious infection in severely ill or immunocompromised children, so this is an individual decision that needs their input.
Does this contain any fillers or artificial ingredients?
The active ingredients are all live bacteria. The inactive ingredients include xylitol (a sugar alcohol sweetener), natural fruit juice and flavors, citric and malic acids, and processing aids like stearic acid, silica, and magnesium stearate—no artificial colors or flavors.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kids Probiotic 3 Billion Berry-licious is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kids Probiotic 3 Billion Berry-licious label
Go deeper

The Full Monographs Behind Kids Probiotic 3 Billion Berry-licious’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph →
Sources

Sources & How We Checked

Kids Probiotic 3 Billion Berry-licious's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 44 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Bifidobacterium Breve 9 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  4. Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
  5. Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
  6. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  7. Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
  8. Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
  9. Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed

See these in context on the Bifidobacterium Breve monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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