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Dietary supplement

Kombucha 250 mg Ingredients & Drug Interactions

by Digestive Benefits

Kombucha 250 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kombucha 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kombucha 250 mg is a dietary supplement by Digestive Benefits with 1 active ingredient. Its ingredients are commonly taken for general wellness and gut health, digestion, immune support.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kombucha. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kombucha 250 mg by Digestive Benefits

Ask about any prescription or over-the-counter medication and we check it for interactions with Kombucha 250 mg by Digestive Benefits — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kombucha 250 mg by Digestive Benefits

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Kombucha 250 mg is a single-ingredient supplement in capsule form. Each capsule contains kombucha, a fermented tea beverage.

The product also includes inactive ingredients (hypromellose, rice flour, magnesium stearate, and silica) that serve as the capsule material and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Kombucha's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestion and immune system support.
  • We looked for evidence on: Irritable bowel syndrome (IBS), gut health, bacterial balance, digestive function.
  • The closest evidence on file: Kombucha is rated "Insufficient Reliable Evidence To Rate" for Irritable bowel syndrome (IBS) (Natural Medicines).

The evidence supporting kombucha for any of its touted uses—diabetes, irritable bowel syndrome, memory, obesity, and aging—is insufficient in the data we hold. We don't have reliable evidence to rate whether it works for these purposes.

The evidence, ingredient by ingredient Kombucha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Kombucha is usually well tolerated in moderate amounts by healthy adults, but there are real concerns. The product naturally contains small amounts of alcohol and caffeine.

More importantly, kombucha prepared in non-sterile environments or stored in containers with toxic materials can be unsafe. The most common side effects are gastrointestinal complaints like nausea and vomiting.

Rare but serious cases—including cardiac arrest and death—have been reported, as well as cases of severe kidney and metabolic problems following kombucha use. For pregnancy and breastfeeding, the safety data rates kombucha as possibly unsafe.

That means there isn't enough information to know it's safe either way. Talk with your doctor or pharmacist before using this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Kombucha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Kombucha.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you take antidiabetes drugs — kombucha may lower blood sugar further and raise the risk of hypoglycemia. You should also flag it if you're on disulfiram (Antabuse), since kombucha contains alcohol and could trigger a reaction.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Kombucha may appeal to you if you're interested in digestive or metabolic support, but the evidence for its effectiveness isn't established in our data. If you take antidiabetes medications or disulfiram, you'll want to check with your doctor or pharmacist first — the alcohol and glucose-lowering potential pose real risks.

Given the safety concerns around contamination and the rare serious events reported, it's worth a conversation with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kombucha 250 mg, straight from the product label.

Brand Digestive Benefits
Barcode (UPC) 035046107529
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 211790
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kombucha 250 mg by Digestive Benefits, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
035046107529
IngredientAmount% DV
Kombucha250 mg--

Other ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Kombucha originated in China and is widely known as the "tea of immortality." Digestive Benefits Kombucha helps detoxify the body and helps aid in digestion, while inhibiting the growth of unhealthy bacteria. Because it's naturally fermented, Kombucha helps provide a flora balance and antioxidants that promote a healthy immune system, plus naturally supports energy and metabolism.

(Active fermented green tea)

Active enzymes & probiotics

Precautions

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place. Protect from heat, light and moisture.

Formulation

Healthy digestion & immunity

Helps support immune system Full spectrum activity

FDA Statement of Identity

Natural Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule daily as a dietary supplement or as directed by a healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2019 Windmill Health Products All rights reserved.

General Statements

Made in the U.S.A. from globally sourced ingredients.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kombucha 250 mg by Digestive Benefits label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kombucha 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kombucha 250 mg by Digestive Benefits

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Kombucha

Interacts with
87 drugs
250 mg per serving

Kombucha is a fermented tea that many people enjoy as a probiotic-rich beverage, but solid human research proving specific health benefits is lacking....

Kombucha monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kombucha 250 mg by Digestive Benefits Drug Interactions

Want to check YOUR meds against Kombucha 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
86 Moderate 1 Minor

Ingredients driving the most interactions

Kombucha 87

Individual Drug Interactions

The ingredients in Kombucha 250 mg interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in Kombucha 250 mg interact with drugs. Each result below shows which ingredient is responsible. Kombucha

Each ingredient & the kinds of drugs it affects

For each ingredient in Kombucha 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Kombucha2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, kombucha might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that administering kombucha can lower blood glucose levels.

Likelihood Possible Evidence D
Disulfiram (Antabuse)

Theoretically, kombucha might cause a disulfiram reaction when taken with disulfiram.
Kombucha products can contain up to 3.6% alcohol.

Likelihood Possible Evidence D
Kombucha full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kombucha 250 mg, from the product label.

Digestive Benefits

See all Digestive Benefits products
Name
Windmill Health Products
Street Address
10 Henderson Drive
City
West Caldwell
State
NJ
ZipCode
07006
Web Address
www.windmillvitamins.com
Pharmacist Counseling Corner

Kombucha 250 mg by Digestive Benefits: Common Questions

Does Kombucha 250 mg by Digestive Benefits interact with any medications?
Yes. Based on its ingredients, Kombucha 250 mg has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kombucha 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take kombucha if I have diabetes?
Not without checking first. Animal research shows kombucha can lower blood glucose, so taking it alongside diabetes medication might push your blood sugar too low. Talk with your doctor or pharmacist before adding this to your routine.
Is kombucha safe during pregnancy or breastfeeding?
The safety data rates it as possibly unsafe during pregnancy and lactation — meaning there isn't enough information to know either way. You'll need to talk with your doctor or pharmacist for personalized advice.
What are the side effects of kombucha?
Most commonly, people report gastrointestinal complaints like nausea and vomiting. Serious but rare events — cardiac arrest, death, kidney failure, and severe metabolic problems — have been reported, especially when kombucha is prepared or stored unsafely.
Does kombucha actually work for digestion or weight loss?
The evidence we hold isn't strong enough to rate whether it works for digestion, weight loss, memory, or any of its other claimed uses. We'd need more reliable research.
Can I take kombucha with Antabuse?
You should check with your doctor first. Kombucha contains small amounts of alcohol, and Antabuse is designed to create an unpleasant reaction if you drink. Mixing them could trigger nausea, flushing, and chest discomfort.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kombucha 250 mg label
Go deeper

The Full Monographs Behind Kombucha 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Kombucha

Interacts with 87 drugs

Kombucha is a fermented tea that many people enjoy as a probiotic-rich beverage, but solid human research proving specific health benefits is lacking. It is generally fine in moderate amount...

Read the full Kombucha monograph →
Sources

Sources & How We Checked

Kombucha 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Kombucha 15 references
  1. Phan TG, Estell J, Duggin G, et al. Lead poisoning from drinking Kombucha tea brewed in a ceramic pot. Med J Aust 1998;169:644-6. PubMed
  2. FDA Talk Paper. FDA Cautions Consumers on "Kombucha Mushroom Tea." Available at: www.vm.cfsan.fda.gov/~lrd/TPMUSHRM.html
  3. Kombucha-toxicity alert. Crit Path AIDS Proj, 1994;30:31-32 1994-5.
  4. CDC. Unexplained severe illness possibly associated with consumption of Kombucha tea-Iowa, 1995. MMWR Morb Mortal Wkly Rep 1995;44:892-3,899-900.
  5. Srinivasan R, Smolinske S, Greenbaum DJ. Probable gastrointestinal toxicity of Kombucha tea: is this beverage healthy or harmful? J Gen Intern Med 1997;12:643-4. PubMed
  6. Ernst, E. Kombucha: a systematic review of the clinical evidence. Forsch.Komplementarmed.Klass.Naturheilkd. 2003;10(2):85-87. PubMed
  7. Derk, C. T., Sandorfi, N., and Curtis, M. T. A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage. Clin.Rheumatol. 2004;23(4):355-357. PubMed
  8. Sabouraud, S., Coppere, B., Rousseau, C., Testud, F., Pulce, C., Tholly, F., Blanc, M., Culoma, F., Facchin, A., Ninet, J., Chambon, P., Medina, B., and Descotes, J. [Environmental lead poisoning from lead-glazed earthenware used for storing drinks]. Rev
  9. SungHee, Kole A., Jones, H. D., Christensen, R., and Gladstein, J. A case of Kombucha tea toxicity. J.Intensive Care Med. 2009;24(3):205-207. PubMed
  10. Aloulou, A., Hamden, K., Elloumi, D., Ali, M. B., Hargafi, K., Jaouadi, B., Ayadi, F., Elfeki, A., and Ammar, E. Hypoglycemic and antilipidemic properties of kombucha tea in alloxan-induced diabetic rats. BMC.Complement Altern.Med. 2012;12:63. PubMed
  11. McNaughton, C. and Eidsness, L. M. Ethics of alternative therapies. S.D.J.Med. 1995;48(7):209-211.
  12. No author. Unexplained severe illness possibly associated with consumption of Kombucha tea--Iowa, 1995. From the Centers for Disease Control and Prevention. JAMA 1-10-1996;275(2):96-98.
  13. Jakubczyk K, Kałduńska J, Kochman J, Janda K. Chemical Profile and Antioxidant Activity of the Kombucha Beverage Derived from White, Green, Black and Red Tea. Antioxidants (Basel). 2020;9(5):E447. doi: 10.3390/antiox9050447. PubMed
  14. Jang SS, McIntyre L, Chan M, Brown PN, Finley J, Chen SX. Ethanol concentration of kombucha teas in British Columbia, Canada. J Food Prot 2021;84(11):1878-83. PubMed
  15. Xu S, Wang Y, Wang J, Geng W. Kombucha reduces hyperglycemia in type 2 diabetes of mice by regulating gut microbiota and Its metabolites. Foods 2022;11(5):754. PubMed

See these in context on the Kombucha monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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