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Dietary supplement

L-Glutamine 1000 mg Capsules Ingredients & Drug Interactions

by BulkSupplements.com

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Glutamine 1000 mg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Glutamine 1000 mg Capsules by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine at 1,000 mg per capsule. Glutamine is an amino acid — one of the building blocks your body uses to make proteins and support immune and digestive function.

The capsule itself is made from bovine gelatin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glutamine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Glutamine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sickle cell disease — rated "Effective" (Natural Medicines).
  • On file: HIV/AIDS-related wasting — rated "Possibly Effective" (Natural Medicines).
  • On file: Critical illness (trauma) — rated "Possibly Effective" (Natural Medicines).
  • On file: Postoperative recovery — rated "Possibly Effective" (Natural Medicines).
  • On file: Pancreatitis — rated "Possibly Effective" (Natural Medicines).

The evidence behind glutamine varies by what you're using it for. It's rated effective for sickle cell disease.

For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is rated possibly effective — meaning there's some supportive data, but more research would strengthen the case. Our data doesn't hold effectiveness ratings for other uses you might encounter.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated in healthy adults. The most common side effects from oral use are mild gastrointestinal ones — belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting.

Headache and musculoskeletal pain have also been reported. A couple of people with bipolar disorder have experienced mania or hypomania at higher doses, but this is rare.

If you have kidney or liver disease, use this only under medical supervision. During pregnancy, the data rates it as likely safe.

During breastfeeding, though, there isn't enough reliable safety information — talk with your doctor or pharmacist before taking supplemental doses.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any anticonvulsant (seizure) medications before you take this. Glutamine theoretically might blunt how they work, though this hasn't been confirmed in humans.

Your exact medication should be screened with the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine may be worth considering if you have sickle cell disease, or if you're recovering from surgery or critical illness and your doctor suggests it. If you take any seizure medication, check your exact drug name on this page first.

People with kidney or liver disease, and those breastfeeding, should talk with their pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutamine 1000 mg Capsules, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X003CQYYJN
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 312915
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutamine 1000 mg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
X003CQYYJN
IngredientAmount% DV
L-Glutamine1000 mg--

Other ingredients: Bovine Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Glutamine 1000 mg per serving

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 2 capsules once or twice daily, or as directed by a physician.

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, dairy, yeast, soy, gluten, additives

Storage

Store in a dry, cool place

General Statements

New Scan me

See for yourself

L-Glutamine 1000 mg Capsules by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Glutamine 1000 mg Capsules by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
1000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Other (inactive) ingredients: Bovine Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutamine 1000 mg Capsules by BulkSupplements.com Drug Interactions

Want to check YOUR meds against L-Glutamine 1000 mg Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Glutamine 1000 mg Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Glutamine 1000 mg Capsules, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

L-Glutamine 1000 mg Capsules by BulkSupplements.com: Common Questions

Does L-Glutamine 1000 mg Capsules by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, L-Glutamine 1000 mg Capsules has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Glutamine 1000 mg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-glutamine safe if I'm pregnant?
Yes — the safety data rates it as likely safe during pregnancy. If you have other health conditions or take medications, it's still smart to mention it to your doctor at your next visit.
What if I'm breastfeeding?
There isn't enough reliable safety information for supplemental doses while breastfeeding. Talk with your doctor or pharmacist for personalized advice before starting.
What are the most common side effects?
Mild gastrointestinal effects — bloating, belching, flatulence, constipation, diarrhea, nausea, and vomiting — are the most frequent. Headache and muscle pain have also been reported. These tend to be manageable, but let us know if they're bothersome.
Can I take this if I have kidney disease?
You should only use glutamine under medical supervision if you have kidney or liver disease. Check with your doctor first because your kidneys and liver play a big role in how your body processes it.
Will this help me recover faster after surgery?
The evidence suggests glutamine is possibly effective for postoperative recovery, so there's some scientific support — but more research would confirm it. Talk with your surgeon or doctor about whether it's right for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutamine 1000 mg Capsules is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutamine 1000 mg Capsules label
Go deeper

The Full Monographs Behind L-Glutamine 1000 mg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Glutamine 1000 mg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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