L-Lysine 1000 mg Ingredients & Drug Interactions
by Country Life
What is this page for?
First and foremost: checking L-Lysine 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Lysine 1000 mg is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 211 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Lysine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against L-Lysine 1000 mg by Country Life
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HelloPharmacist Scorecard of L-Lysine 1000 mg by Country Life
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: vitamin B6 and L-lysine. Vitamin B6 is a B-complex vitamin your body needs for nerve function, immune response, and breaking down proteins.
L-Lysine is an amino acid — one of the building blocks your body uses to make protein. The tablet also contains several inactive ingredients (cellulose, stearic acid, magnesium stearate, cellulose and glycerin coating, silica, and vegetable glaze) that help form and coat the pill.
Does it work?
Moderate evidence
For vitamin B6: it's been shown effective for treating sideroblastic anemia and vitamin B6 deficiency, and likely effective for lowering high homocysteine levels. It's possibly effective for pregnancy-related nausea and vomiting, though use requires a doctor's guidance.
For L-lysine: the evidence suggests it's possibly effective for cold sores (herpes labialis). The data we hold doesn't establish effectiveness for child growth, pressure ulcers, or diabetic foot ulcers.
How safe is it?
Well-documented data
Vitamin B6 is well tolerated at doses under 100 mg daily, but the most common side effects include abdominal pain, allergic reactions, headache, heartburn, loss of appetite, nausea, and drowsiness. High doses over time — especially above 1,000 mg per day — can cause nerve damage (sensory neuropathy); you're at highest risk with total doses of 1,000 grams or more, though it can happen at lower amounts too.
L-Lysine is generally well tolerated, with the most common side effects being stomach pain, diarrhea, and indigestion. Long-term safety at high doses hasn't been well studied.
For pregnancy, lysine from food is fine, but supplement safety during pregnancy and breastfeeding isn't well established — talk with your doctor before using it if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check it with your doctor or pharmacist if you take blood pressure medications, seizure medications (phenobarbital or phenytoin), amiodarone for heart rhythm, or levodopa for Parkinson's — especially if you take levodopa without carbidopa. Also check if you use any 5-HT4 agonists for gut issues.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product makes sense if you're looking to supplement L-lysine for cold sores or to get extra vitamin B6 — but the vitamin B6 content means you'll want to check it against any blood pressure medications, seizure medications, amiodarone, or levodopa you're taking with your own doctor or pharmacist. At the 1,000 mg dose here, L-lysine is unlikely to cause problems, but watch for stomach upset.
If you're pregnant or breastfeeding, ask your pharmacist or doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Lysine 1000 mg, straight from the product label.
| Brand | Country Life |
|---|---|
| Barcode (UPC) | 015794013105 |
| Net contents | 50 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Oct 25, 2012 |
| DSLD ID | 13080 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Lysine 1000 mg by Country Life, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin B6 | 25 mg | 1250% |
| L-Lysine | 1000 mg | -- |
Other ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Cellulose & Glycerin Coating, Silica, Vegetable Glaze
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
AMINO ACIDS Amino Acid Supplement with B6
B6 aids in the utilization of Lysine.
Seals/Symbols
K PARVE
Certified Vegan AVA(TM) American Vegetarian Association Certified GF(R) Gluten-Free Good Manufacturing Practices GMP CERTIFIED Our manufacturing supports wind power renewablechoice.com PLEASE RECYCLE
Precautions
WARNING: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product. If any adverse reactions occur, stop taking the product and consult your doctor.
Do not accept if seal is broken.
Keep out of the reach of children.
General
Product No. 1310 11K11L
Storage
Store between 59(0)-86(0)degrees F.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Adults take one (1) tablet daily, or as directed by your health care provider. As a reminder, discuss the supplements and medications that you take with your health care providers.
Formulation
NO: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, preservatives or artificial color.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Lysine 1000 mg by Country Life label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Lysine 1000 mg by Country Life
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin B6
Interacts with210 drugs
Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...
Vitamin B6 monograph & interactionsL-Lysine
Interacts with1 drug
Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to t...
L-Lysine monograph & interactionsOther (inactive) ingredients: Cellulose, Stearic Acid, Magnesium Stearate, Cellulose & Glycerin Coating, Silica, Vegetable Glaze. These complete the product’s ingredient list but are not active constituents.
L-Lysine 1000 mg by Country Life Drug Interactions
HelloPharmacist Interaction Report
Country Life's L-Lysine 1000 mg contains vitamin B6, which does interact with several medications.
The most serious concern is with blood pressure drugs (antihypertensives) — vitamin B6 may add to their effect and lower your blood pressure further than intended.
Read the full breakdown — every affected drug type, severity by severity
Vitamin B6 also interacts with a few other drug types. It may increase the photosensitivity (skin sensitivity to sun) caused by amiodarone, a heart rhythm medication.
It can reduce how well seizure medications like phenobarbital and phenytoin work by speeding up how your body clears them — a Moderate-severity concern. If you take levodopa alone for Parkinson's disease, vitamin B6 may reduce its effects, though this doesn't happen if you're taking it with carbidopa (the combination Sinemet).
L-Lysine itself has one documented interaction: it may theoretically reduce the effects of 5-HT4 agonists, a class of drugs sometimes used for gastrointestinal issues — a Minor-severity concern.
Altogether, these interactions span 211 individual medications. Use the interaction checker on this page to look up your exact medications before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against L-Lysine 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in L-Lysine 1000 mg interact with 211 drugs. Click any drug to see the details.
2 of the 2 ingredients in L-Lysine 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Lysine
AcebutololRhotral, Sectral
How Acebutolol interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amiloride, Hydrochlorothiazide interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Amiodarone (cordarone) Moderate
Interaction Summary
Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Read the full Vitamin B6 + Amiodarone interactionAmlodipineNorliqva
How Amlodipine interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Ammonium Chloride interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Aprobarbital, Butabarbital, Phenobarbital interactionAprocitentanTryvio
How Aprocitentan interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Aprocitentan interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Aspirin, Codeine Phosphate, Phenobarbital interactionAtenololAtenix, Tenormin
How Atenolol interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Atenolol, Chlorthalidone interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Atropine, Phenobarbital interactionAzilsartanEdarbi
How Azilsartan interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Azilsartan, Chlorthalidone interactionBelladona Extract, PhenobarbitalChardonna-2
How Belladona Extract, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Belladona Extract, Phenobarbital interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna Alkaloids, PhenobarbitalBarbidonna, Donnatal
How Belladonna Alkaloids, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Belladonna Alkaloids, Phenobarbital interactionBelladonna Extract, PhenobarbitalBelap
How Belladonna Extract, Phenobarbital interacts with L-Lysine 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Belladonna Extract, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in L-Lysine 1000 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B6
Amiodarone (Cordarone)
Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.
Antihypertensive Drugs
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.
Phenobarbital (Luminal)
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.
Phenytoin (Dilantin)
High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.
Levodopa
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.
L-Lysine
5-Ht4 Agonists
Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.
Brand information
Manufacturer and brand details for L-Lysine 1000 mg, from the product label.
Country Life
See all Country Life products- Name
- Country Life, LLC
- Street Address
- 180 Vanderbilt Motor Parkway
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Web Address
- CountryLifeVitamins.com
L-Lysine 1000 mg by Country Life: Common Questions
Does L-Lysine 1000 mg by Country Life interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
Does L-lysine really help with cold sores?
What are the side effects of vitamin B6 at this dose?
Is this just L-lysine or does it have other stuff in it?
Can I take this with my blood pressure medicine?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Lysine 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Lysine 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin B6
Interacts with 210 drugsVitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...
Read the full Vitamin B6 monograph → Herb & supplement monographLysine
Interacts with 1 drugLysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...
Read the full Lysine monograph →Sources & How We Checked
L-Lysine 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 39 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin B6 32 references
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
- South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
- Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
- Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
- Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
- Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
- Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
- Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
- Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
- Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
- Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
- Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
- Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
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