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Dietary supplement

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor Ingredients & Drug Interactions

by Labrada Nutrition

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor is a dietary supplement by Labrada Nutrition with 3 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,035 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Potassium” is listed as a grouped ingredient — the label gives one combined amount (150 mg) without saying how much of each component you get.

This shake contains 2 active ingredients: sodium and potassium. Both are essential minerals your body needs for nerve and muscle function, heart rhythm, and fluid balance.

They come here as naturally occurring components of whey protein isolate and other food-based ingredients in the powder, not as added mineral supplements. The shake also contains whey protein isolate as the main protein source, plus inactive ingredients like sunflower oil, inulin (a fiber), cane sugar, natural flavors, xanthan gum, sea salt, monk fruit extract, and soy lecithin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Effective" (Black Psyllium) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Black Psyllium) (Natural Medicines).
  • On file: Cystic fibrosis — rated "Likely Effective" (Sodium) (Natural Medicines).
  • On file: Amphotericin B nephrotoxicity — rated "Possibly Effective" (Sodium) (Natural Medicines).

The data we hold doesn't establish an effectiveness rating for sodium or potassium as ingredients in this shake for any fitness or health outcome. Sodium has effectiveness ratings for cystic fibrosis (likely effective) and preventing kidney damage from amphotericin B (an antifungal drug used in hospitals), but those are specialized medical uses unrelated to this product's purpose as a protein shake.

The evidence, ingredient by ingredient Sodium Potassium Black Psyllium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated in normal dietary amounts—the level you'd get from food and this shake. However, consistently high sodium intake is linked to high blood pressure and can strain your heart and kidneys.

Potassium from food is generally safe, but supplements can raise blood levels dangerously in people with kidney disease or certain conditions. Both minerals in this shake come from food sources rather than concentrated supplements, so the amounts are much lower than a supplement would provide.

That said, the data flags that very high sodium intake over time is associated with increased gastric cancer risk and bone loss, and high potassium can cause nausea, vomiting, abdominal pain, diarrhea, and in rare cases, dangerous heart rhythm changes. For pregnancy, sodium is rated likely safe to possibly unsafe (the data holds conflicting safety information); potassium is rated likely safe.

Talk with your doctor or pharmacist if you're pregnant or breastfeeding and have questions about sodium or potassium from food and supplements.

Side effects, ingredient by ingredient Sodium Potassium Black Psyllium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,036 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist if you take blood pressure medications (antihypertensives), heart failure or kidney disease medications, lithium, corticosteroids, ACE inhibitors, angiotensin receptor blockers, potassium-sparing diuretics, or HIV medications—all can be affected by the sodium and potassium in this shake, and the risks are most serious for blood pressure control and potassium levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This shake is a straightforward whey protein product with sodium and potassium from food ingredients rather than supplements—dietary amounts of both are generally well tolerated. If you take blood pressure medications, heart drugs, water pills, lithium, or HIV medications, or if you have kidney disease, check your exact medications with your doctor or pharmacist before using this product regularly, since the sodium and potassium could affect how some of those drugs work.

Otherwise, a single shake is unlikely to pose a concern for most people.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor, straight from the product label.

Brand Labrada Nutrition
Barcode (UPC) 710779334007
Net contents 24 oz.; 680 Gram(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 41027
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
40 Gram(s)
Maximum serving Sizes:
40 Gram(s)
Servings per container
17
UPC/BARCODE
710779334007
IngredientAmount% DV
Calories150 {Calories}--
Total Carbohydrates6 Gram(s)2%
Sugar4 Gram(s)--
Calories from Fat30 {Calories}--
Dietary Fiber3 Gram(s)12%
Protein25 Gram(s)50%
Saturated Fat1 Gram(s)--
Sodium150 mg3%
Trans Fat0 Gram(s)--
Potassium150 mg4%
Cholesterol17 mg6%
Total Fat3 Gram(s)5%

Other ingredients: cross-flow micro ultrafiltered Whey Protein Isolate, Sunflower Oil, Calcium Caseinate, Inulin, Cane Sugar, Natural Flavors, Xanthan Gum, Sea Salt, Monk Fruit extract, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Allergen Information: Contains Milk, Soy.

Formula

Allergen Information: Contains Milk, Soy.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

NO Gluten Lactose Artificial Flavors Artificial Colors Preservatives Artificial Sweeteners

NO Preservatives Gluten or Lactose Artificial Sweeteners Artificial Colors or Flavors

Suggested/Recommended/Usage/Directions

Directions: Glass - Fill glass with 5-6 oz. of water or your favorite beverage. Add 1 scoop (~40g) of Lean Body(R) for Her Whey Protein Isolate Shake, and mix with a spoon. Shaker - Fill shaker with 5-6 oz. of water or your favorite beverage. Add 1 scoop (~40g) of Lean Body(R) for Her Whey Protein Isolate Shake. Cover and shake. Blender - Fill blender with 5-6 oz. of water or your favorite beverage. Add 1 scoop (~40g) of Lean Body(R) for Her Whey Protein Isolate Shake, cover and blend.

General Statements

Made with Natural Ingredients

SCAN ME for More Information~ {QR Code}

MADE IN U.S.A.

Healthy Weight Management System

{signature} Jamie Eason

8x Less Plastic Waste

Easy Open, Resealable Pouch

Healthy, natural nutrition plays a major part in whether you are successful getting leaner, healthier and more toned.

My Whey Protein Isolate shake not only tastes incredibly delicious, it's made with wholesome, natural ingredients. My philosophy is to keep it simple, as natural as possible, and delicious.

Calories per gram: Fat 9 Carbohydrate 4 Protein 4

Brand IP Statement(s)

(C)2014 LBN, Inc.

"As a former champion figure competitor and creator of the LiveFit(TM) Trainer, I have helped hundreds of thousands of women reach their fitness goals.

That's why I teamed up with Labrada Nutrition, the most trusted name in sports nutrition, to develop my signature line of Lean Body(R) For Her Natural nutritional supplements for women.

Use Lean body(R) for Her whey protein isolate as an excellent source of highly bio-available protein to repair and build lean muscle, support your immune system, and enjoy greater health.

Seals/Symbols

eco-friendly

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size40 Gram(s) Dosage formPowder Servings per container17 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

25 Gram(s) per serving

Sodium

Interacts with
205 drugs
150 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
150 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Other (inactive) ingredients: Cross-flow micro ultrafiltered Whey Protein Isolate, Sunflower Oil, Calcium Caseinate, Inulin, Cane Sugar, Natural Flavors, Xanthan Gum, Sea Salt, Monk Fruit extract, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition Drug Interactions

Want to check YOUR meds against Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,035Drugs
242 Moderate 1,793 Minor

Ingredients driving the most interactions

Sodium 205
Potassium 62

Individual Drug Interactions

The ingredients in Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor interact with 2,035 drugs. Click any drug to see the details.

2 of the 3 ingredients in Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Sodium Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor, from the product label.

Labrada Nutrition

See all Labrada Nutrition products
Name
Labrada Nutrition
Street Address
333 Northpark Central Dr.
City
Houston
State
TX
ZipCode
USA
Phone Number
1.800.832.9948
Web Address
www.labrada.com
Pharmacist Counseling Corner

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition: Common Questions

Does Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor by Labrada Nutrition interact with any medications?
Yes. Based on its ingredients, Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor has a known interaction with 2,035 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this shake have a lot of sodium?
The sodium and potassium here come from food sources in the protein isolate and sea salt, not added mineral supplements, so the amounts are the same as you'd find in a comparable food meal. That's much lower than a sodium supplement would provide—but if you're watching sodium for blood pressure or heart health, check the nutrition label for the exact amount and talk it over with your doctor.
Is this safe during pregnancy?
Sodium in food during pregnancy is rated likely safe, though some data suggests possibly unsafe—the evidence is mixed and we don't have a clear answer. Potassium from food is rated likely safe. Since the data here is incomplete, talk with your doctor or pharmacist for personalized advice on using this shake while pregnant.
Can I use this if I'm breastfeeding?
Dietary sodium and potassium from food are generally appropriate while breastfeeding, but check with your doctor or pharmacist before making this a regular part of your diet, especially if you have kidney issues or take medications that affect sodium or potassium levels.
What is this shake made for?
This is a whey protein shake designed as a meal replacement or protein supplement. The active ingredients—sodium and potassium—are present as naturally occurring minerals in the whey and other food ingredients, not for any specific therapeutic effect beyond what protein and electrolytes normally do for your body.
Can I drink this every day?
One shake daily is unlikely to cause problems for most people, since the sodium and potassium are at food levels. If you drink multiple shakes daily or have kidney disease, high blood pressure, or take medications that interact with sodium or potassium, check with your doctor or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor label
Go deeper

The Full Monographs Behind Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph →
Sources

Sources & How We Checked

Lean Body For Her Whey Protein Isolate Shake Natural Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 68 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
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See these in context on the Sodium monograph →

Potassium 12 references
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  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
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See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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