Interactions on record — worth a quick check against your medications. Based on 1 of 7 ingredients. Check your meds →
Dietary supplement

LG5 PRO Ingredients & Drug Interactions

by All American EFX

Liquid Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

LG5 PRO is a dietary supplement by All American EFX with 7 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 222 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dextro-Cyclodized Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of LG5 PRO by All American EFX

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 8 active ingredients.
  • “Active Ingredients” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “LG5 Amplifying Matrix” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

LG5 PRO is a liquid supplement with 8 active ingredients. The main players are taurine and glutamine (supplied as both Glutamine Hydrochloride and Dextro-Cyclodized Glutamine), plus aspartic acid — all amino acids tied to muscle recovery and athletic performance.

The product also contains fat and fiber for nutritional support and includes a proprietary delivery system called pH-Xact to help your body absorb and use these ingredients. The supplement's "LG5 Amplifying Matrix" is a blend of components listed separately, so you're getting their combined effect rather than one mystery ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and athletic performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Physical performance, Muscle strength, Postoperative recovery — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma) (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.

The evidence for what this product actually does is limited and mixed. For athletic performance, muscle strength, and fatigue, aspartic acid shows insufficient evidence — we simply don't have reliable data showing it works.

Taurine is possibly effective for congestive heart failure (low ejection fraction) and possibly ineffective for weight loss. Glutamine (in both forms here) is rated effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, trauma recovery, and bounce-back after surgery — though those last two are based on limited evidence.

Bottom line: if you're taking this for general athletic performance or energy, the science backing these amino acids is sparse.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taurine is generally well tolerated in typical doses for up to a year, though long-term safety data is thinner. The most common side effects are constipation, diarrhea, and indigestion.

Rare allergic reactions have been reported, especially in people sensitive to sulfites or sulfonamides. Glutamine (both forms) is also generally well tolerated in healthy adults, but common side effects include bloating, gas, nausea, diarrhea, and stomach pain — particularly at higher doses.

A handful of case reports describe dizziness, headache, and mood changes (mania or hypomania) in people with bipolar disorder. Aspartic acid in supplement doses hasn't been well studied for long-term safety.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Glutamine, Taurine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; lithium.
  • For scale: 222 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on anticonvulsant (seizure) medications — glutamine may reduce their effect. If you take blood pressure medications or lithium, taurine can interact with both.

Blood pressure drugs may cause your pressure to drop too far; lithium levels may climb and become unsafe. These are the main flags to run through your own healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

LG5 PRO is an amino acid blend aimed at muscle recovery and athletic performance, but evidence that it works for those goals is sparse. The real concern is its interactions with blood pressure and seizure medications, and especially with lithium — if you're on any of those, check with your doctor or pharmacist before adding this.

If you have kidney or liver disease, glutamine warrants medical supervision. It's generally well tolerated otherwise, but gas, bloating, and stomach upset are common.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LG5 PRO, straight from the product label.

Brand All American EFX
Barcode (UPC) 737190001424
Net contents 16 fl. Oz.; 473 mL
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 627
Product type Amino Acid/protein
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LG5 PRO by All American EFX, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tbsp
Maximum serving Sizes:
1 Tbsp
Servings per container
31
UPC/BARCODE
737190001424
IngredientAmount% DV
Calories10 {Calories}--
Sugar0 g--
Calories from Fat0 {Calories}--
Protein0 g--
Aspartic Acid0 NP--
Taurine0 NP--
Carbohydrates2.5 g1%
Fat0 g--
Fiber0 g--
Active Ingredients0 NP--
Glutamine Hydrochloride0 NP--
Sugar Esters2.5 g--
Dextro-Cyclodized Glutamine3000 mg--
LG5 Amplifying Matrix1000 mg--
Ribonucleic Acid0 NP--

Other ingredients: a proprietary pH-Xact liquid-based delivery system

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

(C)2008 All American EFX(R) All Rights Reserved.

All American(R) is a registered trademark of (AAP)

Dextro-Cyclodized(TM) Liquid Glutamine & Cell Volumizer

FEATURING: pH-Xact(TM) Delivery Technology

Get Noticed(TM)

LG5 PRO(TM) utilizes a pharmaceutical liquid controlled delivery system powered by our pH-XACT(TM) technology that’s truly at the leading edge of innovation. Now your gut doesn’t stand a chance, and you finally get a powerful dose of glutamine exactly where you need it most — in your muscle cells.

pH-Xact(TM) delivery technology ensures optimal bioavailability of our formulas by giving them the precise pH levels necessary to rapidly shuttle nutrients to the bloodstream with maximum potency.

pH-Xact(TM) is a registered trademark of All American EFX(R)

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Precautions

Warnings: Do not use if you are pregnant or nursing. Not intended for any persons under the age of 18. Seek the advice of your healthcare professional if you have any medical condition or are taking any medications. Discontinue use if you are experiencing any side-effects.

Storage

Keep lid tightly closed in a cool, dry place away from children.

General Statements

*For maximum potency & bioavailability

*Repair * Cell Volume * Preservation*

Dextro-Cyclodized(TM) Glutamine & Amplifying Matrix

Glutamine has been scientifically shown to be a poorly absorbed compound due to the “glutamine hungry” cells in the lining of the stomach. Therefore, vast amounts get trapped and do NOT get into your bloodstream in sufficient quantities to “feed” your muscles with its intense anabolic/anti-catabolic properties.

GROWTH/RECOVERY

If you’re after faster recovery and growth…you want to feel fuller, harder, and crank up your immune system, then LG5 PRO(TM) is just right for you.

In God We Trust EU Plant #1000135313

pH-Xact Delivery Technology It's not how much you take, it's how much you absorb.

RASPBERRY RAGE

U.S. and International Patents Pending.

Your daily values may be higher or lower depending on your caloric needs.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: As a dietary supplement, for optimal results on training days take 1 TBSP post-workout and 1 TBSP before bedtime. On non-training days take 2 TBSP(s) before bedtime. Shake well. No refrigeration needed, but may enhance flavor.

General

CO# AAL141T-16

See for yourself

LG5 PRO by All American EFX label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in LG5 PRO by All American EFX

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tbsp Dosage formLiquid Servings per container31 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

0 g per serving

Carbohydrates

2.5 g per serving
  • › Sugar
  • › Fiber
  • › Sugar Esters

Fat

0 g per serving

Active Ingredients

0 NP per serving

Other (inactive) ingredients: A proprietary pH-Xact liquid-based delivery system. These complete the product’s ingredient list but are not active constituents.

Interaction report

LG5 PRO by All American EFX Drug Interactions

Want to check YOUR meds against LG5 PRO?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
222Drugs
222 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in LG5 PRO with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dextro-Cyclodized Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for LG5 PRO, from the product label.

All American EFX

See all All American EFX products
Name
All American EFX(R)
Phone Number
(888)238-1864
Web Address
www.aaefx.com
Pharmacist Counseling Corner

LG5 PRO by All American EFX: Common Questions

Does LG5 PRO by All American EFX interact with any medications?
Yes. Based on its ingredients, LG5 PRO has a known interaction with 222 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LG5 PRO contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this have any fillers?
The product contains a proprietary pH-Xact liquid-based delivery system as an inactive ingredient, which helps your body absorb the amino acids. Beyond that, the active ingredients are the amino acids themselves.
Is taurine safe for long-term use?
Taurine is generally well tolerated short-term in healthy adults, but long-term safety is less certain and hasn't been thoroughly studied. If you're thinking of using this long-term, check with your doctor or pharmacist.
Can I take this if I have kidney disease?
The data advises caution — people with kidney or liver disease should use glutamine only under medical supervision. Since this product contains glutamine (two forms, actually), talk with your doctor or pharmacist before starting.
Will this help my athletic performance?
The evidence for aspartic acid in athletic performance is insufficient — we don't have reliable data showing it works. Glutamine has some evidence for recovery after surgery or trauma, but that's limited. Don't expect dramatic results based on current science.
What side effects should I expect?
The most common are gas, bloating, constipation, diarrhea, nausea, and indigestion — especially if you take higher doses. These are usually mild. Rarely, people have had allergic reactions or mood changes, but those are uncommon.
Is it safe during pregnancy?
Taurine is rated likely safe, but aspartic acid and glutamine don't have enough safety data — the facts recommend avoiding them during pregnancy and breastfeeding unless your doctor specifically says to use them. Talk with your doctor or pharmacist about what's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if LG5 PRO is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LG5 PRO label
Sources

Sources & How We Checked

LG5 PRO's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 33 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Aspartic Acid 1 reference
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226 DOI

See these in context on the Aspartic Acid monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
  20. Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
  21. Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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