Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Liquid Carnitine 1000 Natural Vanilla Flavor Ingredients & Drug Interactions

by Iron-Tek

Liquid Carnitine 1000 Natural Vanilla Flavor label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Liquid Carnitine 1000 Natural Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Liquid Carnitine 1000 Natural Vanilla Flavor is a dietary supplement by Iron-Tek with 5 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 229 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek

Ask about any prescription or over-the-counter medication and we check it for interactions with Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains four ingredients: the four active ones are vitamin B6, other carbohydrates, pantothenic acid (also called vitamin B5), and L-carnitine. Vitamin B6 is a B vitamin that helps your body break down proteins and maintain nerve and brain health.

Pantothenic acid is another B vitamin involved in energy production and the health of your skin and hair. L-carnitine is an amino acid your body uses to transport fats into cells for energy.

The product also contains inactive ingredients—purified water, vegetable glycerin, natural vanilla flavor, sodium benzoate, and potassium sorbate—which serve as the liquid base and preservatives.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Supports energy production and fat metabolism.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Chronic fatigue syndrome (CFS), Cancer-related fatigue, Chemotherapy-related fatigue — and 4 related terms.
  • The closest evidence on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS).
  • Also on file: L-carnitine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Cancer-related fatigue, Chemotherapy-related fatigue, Chronic fatigue syndrome (CFS), and more.

Vitamin B6 is effective for treating sideroblastic anemia (a blood disorder) and vitamin B6 deficiency itself, likely effective for lowering homocysteine (an amino acid linked to heart health), and possibly effective for pregnancy-related nausea and vomiting. Pantothenic acid is effective for pantothenic acid deficiency; evidence for other uses like hay fever or hair loss is not established in our data.

L-carnitine is effective for L-carnitine deficiency and possibly effective for high cholesterol, congestive heart failure, and angina. The overall evidence on this product for general wellness is not established in the data we hold.

The evidence, ingredient by ingredient Vitamin B6 Pantothenic Acid L-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated at typical doses, but high doses taken over time can damage nerves, causing tingling and numbness (sensory neuropathy)—doses above 1,000 mg daily carry the most risk, though nerve damage can occur at lower doses too. Common side effects at any dose include abdominal pain, headache, heartburn, nausea, and drowsiness.

Pantothenic acid is considered safe at typical supplement doses with few side effects; orally it's been associated with diarrhea in some cases. L-carnitine is generally well tolerated but may cause stomach upset, nausea, diarrhea, and a fishy body odor at higher doses; rare serious effects include seizures.

Safety data for L-carnitine during breastfeeding is limited, so caution is advised.

Side effects, ingredient by ingredient Vitamin B6 Pantothenic Acid L-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Vitamin B6, L-carnitine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
  • For scale: 229 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood pressure medications, blood thinners (warfarin, acenocoumarol), thyroid hormone replacement, the heart rhythm medication amiodarone, or the seizure drugs phenobarbital or phenytoin. If you take levodopa for Parkinson's disease without carbidopa, also flag it—though the interaction doesn't happen with the combination product Sinemet.

These are the medication types where documented interactions exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help if you have a carnitine or B-vitamin deficiency or if your doctor recommends it for heart health or cholesterol, but it requires careful checking before you start, especially if you take blood pressure medications, blood thinners, thyroid replacement, seizure drugs, or amiodarone. Talk with your doctor or pharmacist about your specific medications and whether this supplement is right for you before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liquid Carnitine 1000 Natural Vanilla Flavor, straight from the product label.

Brand Iron-Tek
Barcode (UPC) 666999144004
Net contents 16 fl. Oz.; 475 mL
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 14284
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tbsp
Maximum serving Sizes:
1 Tbsp
Servings per container
32
UPC/BARCODE
666999144004
IngredientAmount% DV
Calories20 {Calories}--
Total Carbohydrates5 g2%
Sugar1 g--
Vitamin B610 mg500%
Other Carbohydrates4 g--
Pantothenic Acid10 mg100%
L-Carnitine1000 mg--

Other ingredients: purified Water, Vegetable Glycerin, natural Vanilla flavor, Sodium Benzoate, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

-Contains Added B-6 to Aid in the Utilizatoin of Carnitine

General Statements

-Nitrogen Flushed

CLEAN PERFORMANCE

IRON-TEK(R) LIQUID CARNITINE 1000 -Supports Energy Production -Supports the Transport of Long Chain Saturated Fatty Acids into the Cell for Energy Production -Supports Fat Metabolism

See container for "Lot No." and "Best by" date.

-Supports Energy Production -Support Fat Metabolism

FDA Statement of Identity

Dietary Supplement

Precautions

WARNING: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

Keep out of the reach of children.

Notice: Use this product as a food supplement only. Do not use for weight reduction.

Do not accept if seal is broken.

Seals/Symbols

Certified Vegan AVA(TM) American Vegetarian Association Certified GF(R) Gluten-Free Good Manufacturing Practices GMP CERTIFIED PLEASE RECYCLE (recycle) Our manufacturing supports wind power renewablechoice.com

(recycle) 2

CLEAN PERFORMANCE PRODUCT OPTICARN

Storage

Store between 59(0)-86(0) F.

Refrigerate after opening.

General

Product No. 14-400 12A9M

Suggested/Recommended/Usage/Directions

Shake gently before use.

DIRECTIONS FOR USE: Adults, as a dietary supplement, consume 1 (one) tablespoon (15 mL) (0.5 fl. oz.) daily on an empty stomach. Essential Liquid Carnitine 1000 can also be taken 30 minutes before training or as directed by a health care professional. Do not exceed recommended dose. As a reminder, discuss the supplements and medications that you take with your health care providers.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

NO: Yeast, corn, wheat, soy, gluten, milk, starch, artificial color, artificial flavor or artificial sweeteners.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Liquid Carnitine 1000 Natural Vanilla Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tbsp Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 g per serving

Vitamin B6

Interacts with
210 drugs
10 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Other Carbohydrates

4 g per serving

Pantothenic Acid

No known
interactions
10 mg per serving Form: D-Pantothenol, Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

L-Carnitine

Interacts with
19 drugs
1000 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, Natural Vanilla flavor, Sodium Benzoate, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek Drug Interactions

Want to check YOUR meds against Liquid Carnitine 1000 Natural Vanilla Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
229Drugs
224 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
L-Carnitine 19

Individual Drug Interactions

The ingredients in Liquid Carnitine 1000 Natural Vanilla Flavor interact with 229 drugs. Click any drug to see the details.

2 of the 5 ingredients in Liquid Carnitine 1000 Natural Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Carnitine

Each ingredient & the kinds of drugs it affects

For each ingredient in Liquid Carnitine 1000 Natural Vanilla Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

L-Carnitine3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Liquid Carnitine 1000 Natural Vanilla Flavor, from the product label.

Iron-Tek

See all Iron-Tek products
Name
Iron-Tek
Street Address
101 Corporate Drive
City
Hauppauge
State
NY
ZipCode
11788
Pharmacist Counseling Corner

Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek: Common Questions

Does Liquid Carnitine 1000 Natural Vanilla Flavor by Iron-Tek interact with any medications?
Yes. Based on its ingredients, Liquid Carnitine 1000 Natural Vanilla Flavor has a known interaction with 229 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liquid Carnitine 1000 Natural Vanilla Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Vitamin B6 and pantothenic acid are rated likely safe in pregnancy, but vitamin B6 is also rated possibly unsafe—the data is mixed. L-carnitine's pregnancy safety isn't rated in our data. Because these ratings conflict and your individual situation matters, talk with your doctor or pharmacist before taking this product during pregnancy.
Is it safe to breastfeed while taking this?
Vitamin B6 and pantothenic acid are likely safe during breastfeeding. L-carnitine is rated possibly safe, but safety data is limited, so caution is advised. Check with your doctor or pharmacist before using it while nursing.
What is L-carnitine and what does it do?
L-carnitine is an amino acid your body uses to transport fats into cells where they can be burned for energy. It's effective for L-carnitine deficiency and possibly effective for conditions like high cholesterol, heart failure, and angina.
Can high doses of this product cause nerve problems?
Yes—vitamin B6, the main concern, can cause sensory neuropathy (tingling and numbness) at high doses over time, especially above 1,000 mg daily, though it can happen at lower doses too. This product contains vitamin B6, so don't exceed recommended doses without medical guidance.
What are the most common side effects?
From vitamin B6: abdominal pain, headache, heartburn, nausea, and drowsiness. From L-carnitine: stomach upset, nausea, diarrhea, and a fishy body odor at higher doses. Pantothenic acid may cause diarrhea. Most side effects are mild at typical doses.
Does this product have any fillers or other inactive ingredients?
Yes—it contains purified water, vegetable glycerin, natural vanilla flavor, sodium benzoate, and potassium sorbate to serve as the liquid base and preserve freshness.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liquid Carnitine 1000 Natural Vanilla Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liquid Carnitine 1000 Natural Vanilla Flavor label
Go deeper

The Full Monographs Behind Liquid Carnitine 1000 Natural Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph →
Sources

Sources & How We Checked

Liquid Carnitine 1000 Natural Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 84 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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