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Dietary supplement

Liquid Chlorophyll 100 mg Ingredients & Drug Interactions

by The Vitamin Shoppe

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Liquid Chlorophyll 100 mg is a dietary supplement by The Vitamin Shoppe with 2 active ingredients. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 368 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll, Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Liquid Chlorophyll 100 mg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains 2 active ingredients: copper and chlorophyll. Copper is a mineral your body needs in small amounts for nerve function, immune health, and blood cell formation.

Chlorophyll is the green pigment in plants that captures sunlight for photosynthesis. The product also contains vegetable glycerin, deionized water, and peppermint oil as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Superfood antioxidant and wellness support.
  • We looked for evidence on: Colostomy odor, Halitosis, Wound healing, Detoxification, Breath odor.
  • The closest evidence on file: Chlorophyll is rated "Insufficient Reliable Evidence To Rate" for Colostomy odor (Natural Medicines).
  • Also on file: Chlorophyll is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Halitosis.
  • Also on file: Copper is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

The evidence we have on file supports copper for treating copper deficiency—that's the clearest use. For other conditions like Alzheimer's disease, copper appears possibly ineffective based on available data.

For acne, chemotherapy-related anemia, and brain tumors, the evidence isn't established enough for us to rate it. For chlorophyll, the evidence we hold doesn't establish effectiveness for genital herpes, wound healing, shingles, skin cancer, or pancreatitis.

The evidence, ingredient by ingredient Copper Chlorophyll

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is well tolerated in the amounts found in food and standard supplements, though excess copper can be toxic. Copper is actually needed during pregnancy, but stay within recommended amounts and avoid high-dose supplements unless your doctor advises it.

Rare adverse effects from copper include contact dermatitis. People with diabetes tend to have higher copper levels in their blood than those without, though we don't know if that extra copper contributes to diabetes itself.

Chlorophyll is generally well tolerated in short-term use, but high-quality long-term safety data are limited. The most common side effect is photosensitization—a reaction to sunlight.

Rare cases of pseudoporphyria (a condition mimicking porphyria) have been reported after oral chlorophyll use. Chlorophyll is best avoided during pregnancy because there isn't enough reliable safety information, and safety during breastfeeding is unknown—talk with your doctor before using it if you're nursing.

Side effects, ingredient by ingredient Copper Chlorophyll

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chlorophyll, Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 368 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you use methotrexate (a cancer or autoimmune drug), penicillamine (for Wilson's disease or rheumatoid arthritis), birth control pills, or any medication that makes your skin sensitive to sunlight. The chlorophyll and copper in this product can affect how these drugs work or cause harmful interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is mainly useful if you have a documented copper deficiency. If you take methotrexate, penicillamine, birth control pills, or any photosensitizing medication, check with your pharmacist first—there are documented interactions that matter.

During pregnancy and breastfeeding, skip the chlorophyll component and talk with your doctor before using this product at all.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liquid Chlorophyll 100 mg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536026395
Net contents 2 fl. Oz.; 59 mL
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80314
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liquid Chlorophyll 100 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
59
UPC/BARCODE
766536026395
IngredientAmount% DV
Copper4 mg440%
Chlorophyll100 mg--

Other ingredients: Vegetable Glycerin, deionized Water, Peppermint Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Green food Superfood

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free Dairy free Soy free Nut free Does Not Contain: Corn, wheat, gluten, sugar, salt, soy, starch, dairy, citrus, fish, animal derivatives, preservatives, artificial colors or flavors.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, mix one (1) dropper (approximately 30 drops) in water or juice. Shake well before using.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

General

Item No. VS-2639 1769967 ER 28

See for yourself

Liquid Chlorophyll 100 mg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liquid Chlorophyll 100 mg by The Vitamin Shoppe

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container59 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Copper

Interacts with
31 drugs
4 mg per serving

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Chlorophyll

Interacts with
337 drugs
100 mg per serving Form: Chlorophyllin Copper Complex

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...

Chlorophyll monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water, Peppermint Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liquid Chlorophyll 100 mg by The Vitamin Shoppe Drug Interactions

Want to check YOUR meds against Liquid Chlorophyll 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
368Drugs
338 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Each ingredient & the kinds of drugs it affects

For each ingredient in Liquid Chlorophyll 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Liquid Chlorophyll 100 mg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Liquid Chlorophyll 100 mg by The Vitamin Shoppe: Common Questions

Does Liquid Chlorophyll 100 mg by The Vitamin Shoppe interact with any medications?
Yes. Based on its ingredients, Liquid Chlorophyll 100 mg has a known interaction with 368 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Liquid Chlorophyll 100 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control?
You can, but your doctor or pharmacist should know. Copper in this product may raise the copper levels in your blood when you're on birth control—studies show it goes up by an average of 57 micrograms per deciliter, pushing it above normal in most people. It's worth a quick conversation to make sure your doctor is okay with it.
Is this safe during pregnancy?
Copper in amounts you need is safe in pregnancy, but avoid high-dose supplements unless your doctor says otherwise. The chlorophyll component, though, should be avoided—there isn't enough reliable safety data. If you're thinking about using this while pregnant, check with your doctor first.
What's the photosensitization I keep reading about?
Chlorophyll can make your skin more sensitive to sunlight, causing a reaction if you're exposed. It's rare, but there have been case reports of more serious blistering conditions (pseudoporphyria) linked to chlorophyll. If you take this product and spend time in the sun, be aware of any unusual skin reactions.
What is copper actually for in my body?
Copper is a mineral you need for nerve function, making blood cells, supporting your immune system, and helping your body use iron. You only need small amounts, and most people get enough from food—that's why this product is really only useful if you actually have a copper deficiency, diagnosed by your doctor.
Can I take this if I have diabetes?
There's no direct contraindication, but be aware: people with diabetes tend to have higher copper levels in their blood naturally. We don't yet know if extra copper makes diabetes worse, so it's worth mentioning to your doctor before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liquid Chlorophyll 100 mg label
Sources

Sources & How We Checked

Liquid Chlorophyll 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Chlorophyll 5 references
  1. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  2. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  3. Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed

See these in context on the Chlorophyll monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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