Livtone Ingredients & Drug Interactions
by R-U-Ved
What is this page for?
First and foremost: checking Livtone against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Livtone is a dietary supplement by R-U-Ved with 16 active ingredients. Its ingredients are commonly taken for immune support, fever, blood sugar support.Based on those ingredients, 1,389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Barberry, Arjuna, Tinospora cordifolia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Livtone by R-U-Ved
Ask about any prescription or over-the-counter medication and we check it for interactions with Livtone by R-U-Ved — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Livtone by R-U-Ved
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 3 of its 16 active ingredients.
- “Extracts of:” is listed as a grouped ingredient — the label gives one combined amount (350 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 8 of the 9 matched ingredients can interact with medications — European Barberry, Radish, Chirata, Indian Gooseberry, Terminalia, among others.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
- For scale: 1,390 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 6 of the 9 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 9 of 9.
- General safety write-ups exist for 9 of 9.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 10 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Livtone, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Livtone by R-U-Ved, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Tinospora cordifolia | 50 mg | -- |
| Arjuna | 0 NP | -- |
| Amla | 0 NP | -- |
| Boerhaavia diffusa | 50 mg | -- |
| Haritaki | 0 NP | -- |
| Bahera | 0 NP | -- |
| Extracts of: | 350 mg | -- |
| Arka | 0 NP | -- |
| Barberry | 0 NP | -- |
| Bhringraj | 0 NP | -- |
| Bhui Amalaki | 0 NP | -- |
| Chirayata | 0 NP | -- |
| Kalmegh | 0 NP | -- |
| Makoe | 0 NP | -- |
| Radish | 0 NP | -- |
| Sharpunkha | 0 NP | -- |
| Picrorhiza kurroa | 50 mg | -- |
Other ingredients: Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Call us toll free at: 1-800-925-1371
Liver Support
Supports the Livers natural detoxification process for: • Herbicides • Pesticides • Insecticides • Chemicals • Pollution
For more information on these herbs and research, please visit our website at www.ruved.net
Andrographis paniculata has traditionally been used to support liver and heart health. Berberis aristata is a bitter herb that supports liver and gastrointestinal function*. Eclipta alba is known for supporting hair growth and healthy liver function. Picrorhiza kurroa is known for its digestive support and laxative properties which make it great for relief of occasional constipation (not intended to treat chronic constipation). Tinospora cordifolia is also included for its support of healthy inflammatory response and its immune supportive properties*.
Naturally Grown Himalayan Herbs In-house Manufactured to ensure Purity Third Party Tested for Heavy Metals
Seals/Symbols
R-U-VED(R) ancient wisdom, modern lifestyle
FDA Disclaimer Statement
Statements herein have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease or condition.
Formulation
Free from Milk, Soy, Egg and Wheat.
Suggested/Recommended/Usage/Directions
Suggested Use: 1 Capsule three times daily or as directed by you physician.
Brand IP Statement(s)
Livtone(TM) is an ancient formula combining eighteen powerful herbs, the synergistic effects of which make it unique for its liver-supportive properties, while nurturing and maintaining the liver. Traditionally, this formulation has been used as a nutritional support in cases of liver congestion.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Livtone by R-U-Ved label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Livtone by R-U-Ved
These are the 16 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Tinospora cordifolia
Interacts with612 drugs
Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...
Tinospora cordifolia monograph & interactionsBoerhaavia diffusa
Extracts of:
Picrorhiza kurroa
Interacts with207 drugs
Picrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints. Early lab and small h...
Picrorhiza kurroa monograph & interactionsOther (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Livtone by R-U-Ved Drug Interactions
Livtone contains 16 ingredients, and 8 of them have known drug interactions. Altogether they interact with 1,389 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Livtone?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Livtone interact with 1,389 drugs. Click any drug to see the details.
8 of the 16 ingredients in Livtone interact with drugs. Each result below shows which ingredient is responsible. Barberry Arjuna Tinospora cordifolia Kalmegh Amla Picrorhiza kurroa Chirayata Radish
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaImmunosuppressants Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
Read the full Tinospora Cordifolia + 6-mercaptopurine interactionKalmeghImmunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Read the full Kalmegh + 6-mercaptopurine interactionPicrorhiza KurroaImmunosuppressants Moderate
Interaction Summary
Picrorhiza seems to have immunostimulating activity.
Read the full Picrorhiza Kurroa + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Ado-trastuzumab Emtansine interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Livtone — through 4 ingredients. Tap an ingredient for the detail:
KalmeghAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Kalmegh + Abciximab interactionBarberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry + Abciximab interactionBaheraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Bahera + Abciximab interactionAmlaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Abemaciclib interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Abiraterone interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Abiraterone Acetate interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Livtone — through 6 ingredients. Tap an ingredient for the detail:
BarberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry + Abrocitinib interactionTinospora CordifoliaCytochrome P450 2c9 (cyp2c9) Substrates, Immunosuppressants +1 Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
Read the full Tinospora Cordifolia + Abrocitinib interactionKalmeghAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Kalmegh + Abrocitinib interactionPicrorhiza KurroaImmunosuppressants Moderate
Interaction Summary
Picrorhiza seems to have immunostimulating activity.
Read the full Picrorhiza Kurroa + Abrocitinib interactionAmlaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla + Abrocitinib interactionBaheraCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Bahera + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acalabrutinib interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Livtone — through 7 ingredients. Tap an ingredient for the detail:
BarberryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Barberry + Acarbose interactionRadishAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Radish + Acarbose interactionAmlaAntidiabetes Drugs Moderate
Interaction Summary
Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Amla + Acarbose interactionBaheraAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Bahera + Acarbose interactionChirayataAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking chirata concomitantly with antidiabetes drugs may increase the risk of hypoglycemia.
Read the full Chirayata + Acarbose interactionPicrorhiza KurroaAntidiabetes Drugs Moderate
Interaction Summary
Evidence from animal research suggests that an extract of picrorhiza can reduce fasting and non-fasting blood sugar levels.
Read the full Picrorhiza Kurroa + Acarbose interactionTinospora CordifoliaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Tinospora Cordifolia + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Livtone — through 2 ingredients. Tap an ingredient for the detail:
BarberryAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry + Acebutolol interactionKalmeghAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Read the full Kalmegh + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Livtone — through 4 ingredients. Tap an ingredient for the detail:
BaheraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Bahera + Acenocoumarol interactionAmlaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla + Acenocoumarol interactionKalmeghAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Kalmegh + Acenocoumarol interactionBarberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Livtone — through 1 ingredient. Tap an ingredient for the detail:
BarberryAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Livtone — through 1 ingredient. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Livtone — through 5 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Aspirin interactionKalmeghAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Kalmegh + Acetaminophen, Aspirin interactionAmlaAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Amla + Acetaminophen, Aspirin interactionBaheraAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Bahera + Acetaminophen, Aspirin interactionBarberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Livtone — through 5 ingredients. Tap an ingredient for the detail:
BarberryAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry + Acetaminophen, Aspirin, Caffeine interactionKalmeghAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Kalmegh + Acetaminophen, Aspirin, Caffeine interactionTinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Aspirin, Caffeine interactionAmlaAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Read the full Amla + Acetaminophen, Aspirin, Caffeine interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Livtone — through 1 ingredient. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Livtone — through 1 ingredient. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Butalbital, Caffeine interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Butalbital, Caffeine interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Butalbital, Caffeine, Codeine interactionTinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Butalbital, Caffeine, Codeine interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BarberryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry + Acetaminophen, Butalbital, Codeine interactionBaheraCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Bahera + Acetaminophen, Butalbital, Codeine interactionTinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Butalbital, Codeine Phosphate interactionBarberryCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry + Acetaminophen, Butalbital, Codeine Phosphate interactionBaheraCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Bahera + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionTinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionBarberryCns Depressants, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BarberryCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Caffeine, Codeine interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Codeine interactionTinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBarberryCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBaheraCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Dihydrocodeine interactionTinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Dihydrocodeine interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BarberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Caffeine, Isometheptene interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Isometheptene interactionTinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Caffeine, Pyrilamine interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Caffeine, Pyrilamine interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BaheraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionTinospora CordifoliaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Tinospora Cordifolia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
BarberryCns Depressants, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionBaheraCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bahera + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionTinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Livtone — through 3 ingredients. Tap an ingredient for the detail:
Tinospora CordifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Tinospora Cordifolia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionBarberryCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionBaheraCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Bahera + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Livtone with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Barberry
Anticholinergic Drugs
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Anticoagulant/Antiplatelet Drugs
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal evidence suggest that berberine, a constituent of European barberry, might inhibit platelet aggregation. Theoretically, European barberry might have a similar effect.
Antidiabetes Drugs
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical evidence suggests that European barberry juice reduces fasting glucose levels in patients with type 2 diabetes who are also taking antidiabetes drugs. Additionally, some animal studies show that berberine, a constituent of European barberry, has antiglycemic potential. Monitor blood glucose levels closely.
Antihypertensive Drugs
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Animal and human research suggests that European barberry extracts can have hypotensive effects.
Cholinergic Drugs
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Cns Depressants
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Animal research suggests that berberine, a constituent of European barberry, might have sedative effects. Theoretically, European barberry might have a similar effect.
Cyclosporine (Neoral, Sandimmune)
Theoretically, concomitant use with cyclosporine may cause additive effects.
Berberine, a constituent of European barberry, can reduce the metabolism and increase serum levels of cyclosporine. This effect is attributed to the ability of berberine to inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, European barberry might have a similar effect.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
There is very preliminary evidence suggesting that berberine, a constituent of European barberry, might inhibit the CYP3A4 enzyme. Theoretically, European barberry might have a similar effect.
Arjuna
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Tinospora cordifolia
Antidiabetes Drugs
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.
Kalmegh
Anticoagulant/Antiplatelet Drugs
Theoretically, andrographis might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal and laboratory studies suggest that andrographis has antiplatelet effects.
Antihypertensive Drugs
Theoretically, andrographis might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that andrographis has hypotensive effects.
Immunosuppressants
Theoretically, andrographis might interfere with the effects of immunosuppressive drugs.
Laboratory research suggests that andrographolide has immunostimulant activity.
Celecoxib (Celebrex)
Theoretically, andrographis extract might increase the maximum concentration and time to peak concentration of celecoxib. The clinical significance of these changes is unclear.
Animal research suggests that andrographis extract taken orally increases the maximum concentration and time to peak concentration of celecoxib but does not appear to impact the area under the curve.
Etoricoxib (Arcoxia)
Theoretically, andrographis might decrease the absorption of etoricoxib, although the clinical significance is unclear.
Animal research shows that andrographis extract, or the constituent andrographolide, taken orally with etoricoxib decreases the bioavailability of etoricoxib. However, this reduced bioavailability is not correlated with a reduction in the anti-inflammatory effects of etoricoxib in arthritic mice models. The clinical significance of this interaction is unclear.
Glipizide (Glucotrol)
Theoretically, andrographis extract might increase the maximum concentration and area under the curve of glipizide; however, opposite effects are seen with the constituent, andrographolide. The clinical significance of this interaction is unclear.
Animal research suggests that andrographis extract taken orally with glipizide in diabetes-induced rats increases the maximum concentration and area under the curve of glipizide. However, the opposite effect is seen with the constituent, andrographolide, in which the maximum concentration and area under the curve are decreased when taken with glipizide.
Amla
Anticoagulant/Antiplatelet Drugs
Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.
Aspirin
Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.
Clopidogrel (Plavix)
Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.
Picrorhiza kurroa
Antidiabetes Drugs
Evidence from animal research suggests that an extract of picrorhiza can reduce fasting and non-fasting blood sugar levels. Theoretically, picrorhiza might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Immunosuppressants
Picrorhiza seems to have immunostimulating activity. Theoretically, picrorhiza may interfere with immunosuppressant therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).
Chirayata
Antidiabetes Drugs
Theoretically, taking chirata concomitantly with antidiabetes drugs may increase the risk of hypoglycemia.
In non-fasted animals pretreated with the hypoglycemic drug tolbutamide, taking chirata 250 mg/kg decreased blood glucose levels. Monitor blood glucose levels closely.
Radish
Antidiabetes Drugs
Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that radish extract, juice, and sprouts can reduce glucose levels. Animal research also shows that radish root juice 300 mg/kg reduces fasting and postprandial blood glucose in a rat model of diabetes, with effects similar to glibenclamide.
Brand information
Manufacturer and brand details for Livtone, from the product label.
Livtone by R-U-Ved: Common Questions
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Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Livtone’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Tinospora Cordifolia
Interacts with 612 drugsTinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...
Read the full Tinospora Cordifolia monograph → Herb & supplement monographTerminalia
Interacts with 933 drugsTerminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes. Some small studies suggest possible ben...
Read the full Terminalia monograph → Herb & supplement monographIndian Gooseberry
Interacts with 208 drugsIndian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...
Read the full Indian Gooseberry monograph → Herb & supplement monographEuropean Barberry
Interacts with 1,210 drugsEuropean barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolated form. Some early research on berberine is promi...
Read the full European Barberry monograph → Herb & supplement monographChirata
Interacts with 86 drugsChirata is a very bitter herb used in traditional Ayurvedic and South Asian medicine, mainly for digestion, fever, and as a general tonic. Human evidence for its benefits is limited, so it s...
Read the full Chirata monograph → Herb & supplement monographAndrographis
Interacts with 413 drugsAndrographis is a bitter Asian herb traditionally used for colds, flu, and infections, and some studies suggest it may ease cold symptoms and shorten how long they last. The evidence is limi...
Read the full Andrographis monograph → Herb & supplement monographBlack Nightshade
Black nightshade is a wild plant whose cooked ripe berries and leaves are eaten as food in some cultures, but unripe berries and green parts can be poisonous. Human evidence for any health b...
Read the full Black Nightshade monograph → Herb & supplement monographRadish
Interacts with 86 drugsRadish is a common edible root vegetable that is nutritious and generally safe to eat as food. Some people use radish (especially black radish) and its extracts for digestion and liver suppo...
Read the full Radish monograph → Herb & supplement monographPicrorhiza
Interacts with 207 drugsPicrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints. Early lab and small human studies suggest possible liver-prot...
Read the full Picrorhiza monograph →Sources & How We Checked
Livtone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 86 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Tinospora Cordifolia 16 references
- Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
- Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
- Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
- Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
- Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
- Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
- Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
- Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
- Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
- Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
- Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
- Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
- Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
- May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.
See these in context on the Tinospora Cordifolia monograph →
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
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