Major interaction on record — check this product against your medications before combining. Based on 8 of 11 ingredients. Check your meds →

Dietary supplement

Max Protein Chocolate Shake Ingredients & Drug Interactions

Q: Does Max Protein Chocolate Shake by Universal interact with any medications?

Yes. Based on its ingredients, Max Protein Chocolate Shake has a known interaction with 534 medications, including 13 rated major. Use the checker to see how it interacts with a specific drug.

Q: How can one product interact with so many drugs?

Max Protein Chocolate Shake contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.

Q: Where does this information come from?

The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Q: Does this shake have a lot of sodium in it?

The product facts don't specify the exact sodium amount per serving, so you'd need to check the nutrition label. What we do know is that sodium in this shake can interact with blood pressure medications, corticosteroids, and lithium, so if you take any of those, mention it to your doctor before using this product regularly.

Q: Is creatine safe if I have kidney problems?

The safety data advises caution for people with kidney issues. Creatine should only be used by people with kidney disease under medical supervision. If you have any kidney concerns, talk with your doctor or pharmacist before taking this shake.

Q: Can I take this shake while I'm pregnant?

Some ingredients like calcium, potassium, magnesium, and glutamine are rated likely safe in pregnancy, and iron is typically recommended under prenatal guidance. However, creatine safety in pregnancy has not been established and is best avoided. Talk with your prenatal care provider about whether this shake is right for you and in what amounts.

Q: What does creatine do in this shake?

Creatine monohydrate supports muscle strength and athletic performance, and may help with muscle loss (sarcopenia). It's included to aid recovery and muscle building after exercise.

Q: Can I take this shake if I'm breastfeeding?

Most ingredients—potassium, magnesium, and glutamine—are acceptable at appropriate doses while breastfeeding. However, iron is rated likely unsafe, and creatine and taurine should be avoided or used only with caution. Check with your doctor or pharmacist to confirm the dose is right for you and your baby.

Q: What are taurine and glutamine in here for?

Taurine and glutamine are amino acids that support muscle recovery and protein synthesis. They may help with muscle maintenance and postoperative recovery after intense exercise or injury.

by Universal

See full label image

Powder Category: Other Combinations

Most serious interaction: Major

Clinical methodology reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Sep 16, 2026 · Label data from the NIH DSLD

What is this page for?

First and foremost: checking Max Protein Chocolate Shake against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Max Protein Chocolate Shake is a dietary supplement by Universal with 11 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 534 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Magnesium, Sodium, Taurine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Max Protein Chocolate Shake by Universal

Ask about any prescription or over-the-counter medication and we check it for interactions with Max Protein Chocolate Shake by Universal — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds

AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI

Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Max Protein Chocolate Shake by Universal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure

Ingredient Transparency · database check

Full

Every active ingredient lists its own amount on the label.

Why this rating?

The label discloses an exact amount for 9 of its 9 active ingredients.
No proprietary blends here — you can verify the dose of every single component.

Max Protein Chocolate Shake contains 9 active ingredients: sodium, potassium, phosphorus, calcium, iron, magnesium, creatine monohydrate, taurine, and glutamine. These supply electrolytes (sodium, potassium, phosphorus, calcium, magnesium), minerals for recovery and energy (iron, creatine), and amino acids (taurine, glutamine) to support muscle protein synthesis after exercise.

The shake also contains inactive ingredients including the Max Protein blend, natural and artificial flavors, cocoa powder, lecithin, guar gum, and acesulfame potassium as fillers, thickeners, and sweeteners.

Does it work?

Strong evidence

Evidence for Intended Use · database check

By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Anemia of chronic disease via Iron Effective
Constipation via Magnesium Effective
Dyspepsia via Calcium Effective
Hypocalcemia via Calcium Effective
Hypomagnesemia via Magnesium Effective

Why this rating?

We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
On file: Anemia of chronic disease — rated "Effective" (Iron) (Natural Medicines).
On file: Constipation — rated "Effective" (Magnesium) (Natural Medicines).
On file: Dyspepsia — rated "Effective" (Calcium) (Natural Medicines).
On file: Hypocalcemia — rated "Effective" (Calcium) (Natural Medicines).
On file: Hypomagnesemia — rated "Effective" (Magnesium) (Natural Medicines).

Effectiveness data is available for several ingredients but not all. Calcium is rated effective for kidney failure, dyspepsia, low blood calcium (hypocalcemia), high potassium levels (hyperkalemia), and likely effective for osteoporosis.

Iron is effective for iron deficiency anemia and anemia of chronic disease, and possibly effective for heart failure. Magnesium is effective for dyspepsia, constipation, low blood magnesium (hypomagnesemia), and pre-eclampsia.

Creatine is possibly effective for sarcopenia, cerebral creatine deficiency syndromes, muscle strength, and athletic performance. Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

Taurine and sodium lack established effectiveness ratings in the data we hold; effectiveness data for potassium is also not on file.

The evidence, ingredient by ingredient Sodium Potassium Calcium Iron Magnesium Creatine Taurine Glutamine

How safe is it?

Well-documented data

Safety Information · database check

Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?

We hold adverse-effect (side-effect) data for 8 of the 8 matched ingredients.
Pregnancy & breastfeeding safety ratings cover 8 of 8.
General safety write-ups exist for 8 of 8.
Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this shake are generally well tolerated at recommended amounts. Calcium, potassium, iron, and magnesium are generally safe when taken appropriately; however, high intakes can cause problems—calcium and iron can trigger constipation or gastrointestinal upset, and too much potassium or magnesium can cause dangerous heart rhythm changes and other serious effects, especially in people with kidney disease.

Creatine is generally well tolerated in healthy adults but should be used cautiously by those with kidney issues; it can cause water retention, muscle cramps, and diarrhea. Taurine is generally well tolerated short-term in healthy adults, though long-term safety is less certain.

Glutamine is generally well tolerated but people with kidney or liver disease should use it only under medical supervision. For pregnancy: calcium, potassium, magnesium, and glutamine are rated likely safe; iron is likely safe though dosing should be guided by your prenatal care provider; taurine is likely safe; creatine safety has not been established and is best avoided; and creatine monohydrate is rated with insufficient information for breastfeeding.

For breastfeeding: iron is rated likely unsafe; creatine and taurine should be avoided or used with caution; and potassium, magnesium, and glutamine are acceptable when used at appropriate doses. Talk with your doctor or pharmacist about the dose and timing that's right for you, especially if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Sodium Potassium Calcium Iron Magnesium Creatine Taurine Glutamine

Meds to double-check

Major interaction found

Known Interaction Concern · database check

Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?

7 of the 8 matched ingredients can interact with medications — Calcium, Potassium, Glutamine, Iron, Magnesium, among others.
The most serious interaction on file is rated Major.
Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
For scale: 534 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this shake, double-check with your doctor or pharmacist if you take HIV integrase inhibitors (dolutegravir, elvitegravir), the antibiotic ceftriaxone, thyroid medication (levothyroxine), blood pressure drugs (ACE inhibitors, ARBs, or general antihypertensives), lithium, blood thinners, heart rhythm drugs (sotalol, diltiazem), diuretics (including potassium-sparing types), antibiotics (quinolones, tetracyclines, bisphosphonates), seizure medications, or any other medications you're unsure about. The interaction potential is substantial across these ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Max Protein Chocolate Shake can be useful for muscle recovery and protein intake after exercise, but its multiple ingredients—especially calcium, sodium, potassium, iron, and magnesium—interact with a wide range of common medications. If you take any blood pressure medication, thyroid drug, antibiotic, HIV medicine, seizure medication, lithium, or heart rhythm drug, check with your doctor or pharmacist before adding this shake to be sure it won't interfere with your treatment.

Those with kidney disease should also talk it over before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 27, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Max Protein Chocolate Shake, straight from the product label.

Brand	Universal
Barcode (UPC)	039442052155
Net contents	2.2 lbs; 1 kg
Market status	On market
Date entered into DSLD	Oct 27, 2014
DSLD ID	38291
Product type	Other Combinations
Supplement form	Powder
Dietary claims / uses	All Other, Structure/Function
Intended target group(s)	Adult (18 - 50 Years)

From the label

Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Max Protein Chocolate Shake by Universal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):

Adults and children 4 or more years of age

Minimum serving Sizes:

41.5 Gram(s)

Maximum serving Sizes:

41.5 Gram(s)

Servings per container

UPC/BARCODE

039442052155

Ingredient	Amount	% DV
Calories	143 {Calories}	--
Total Carbohydrates	3.5 Gram(s)	1%
Sugar	1 Gram(s)	--
Calories from Fat	9 {Calories}	--
Saturated Fat	1 Gram(s)	3%
Sodium	125 mg	5%
Potassium	268 mg	8%
Cholesterol	25 mg	8%
Phosphorus	138 mg	14%
Calcium	195 mg	19%
Iron	14 mg	80%
Magnesium	25 mg	6%
Creatine Monohydrate	2.5 Gram(s)	--
Taurine	500 mg	--
Total Fat	1 Gram(s)	2%
Trans Fat	0 Gram(s)	--
Protein	30 Gram(s)	60%
Glutamine	1 Gram(s)	--

Other ingredients: Max Protein(TM) Blend, Natural and Artificial flavors, Cocoa powder, L-Glutamine, L-Taurine, Lecithin, Guar Gum, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements

These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.

General

G2712-G-31031

Precautions

Made in a GMP facility on equipment that processes milk, soy, egg, peanuts, tree nuts, fish, shellfish, and wheat.

WARNING: This product is not for use by any individual under the age of 18.

Do not take this product if you have or are at risk for any medical condition or disease including but not limited to diabetes, asthma, depression, recurrent headaches, glaucoma, difficulty urinating, prostate enlargement, seizure disorder, high blood pressure, high cholesterol, arthritis, heart disease, stroke, are pregnant, or are suffering from any inflammatory diseases. Be sure to talk to your physician before using this product if you are using any prescription drug, over-the-counter medication, or supplements. Not for use by children, patients, pregnant or nursing women.

Not for use by children, patients, pregnant or nursing women.

Immediately discontinue use and consult your physician if dizziness, sleeplessness, tremors, nervousness, agitation, headache, heart palpitations, or any side effects occur. Discontinue use two weeks prior to surgery. The use of this product may be banned by some athletic associations. Athletes should consult with their sanctioning authority before use. California Residents Proposition 65 Warning: This product contains a substance known to the State of California to cause birth defects or other reproductive harm.

Exercise good judgment and keep this out of reach of children.

Do not exceed recommended dose.

Formula

INGREDIENT NOTE: This 1g of added glutamine is in addition to the over 4g of naturally occurring glutamine and glutamine peptides contained in the Max Protein(TM) blend.

Each serving of Max Protein(TM) is powered with 30g of the finest proteins available: ultrafiltered whey isolates, hydrolysates and concentrates, isolated casein peptides, and instantized egg albumin proteins.

WPI, WPH, WPC, Egg White Protein & Casein Peptides/ Enhanced with Creatine & Glutamine Peptides

General Statements

Please consult with a physician before using this product.

MADE PROUDLY IN THE U.S.A.

732-545-3130

WHO WE ARE Universal Nutrition has been providing cutting edge and staple nutritional supplements to bodybuilders and hard training athletes the world over since 1977. As time passes, certain ideals never go out of style. Honesty. Integrity. Respect. These are the values we uphold and are the bedrock upon which we built our business. WHAT IT IS Research has shown that the ideal protein consists of blending individual proteins, particularly whey and casein. Together, whey and casein proteins are superior to each individually because of the simple fact that though whey promotes protein synthesis, it does very little for anti-catabolism. Casein, on the other hand, exerts tremendous muscle-sparing effects.

This proprietary blend ensures that protein synthesis is optimized, nitrogen balance is maintained and muscle catabolism is prevented. HOW WE BACK IT UP What is on the label is in the bottle and what is in the bottle will help you reach your goals. We believe it and proudly stand behind every product we manufacture. Our word is our bond.

Storage

Store this product in a cool, dry place, away from heat, moisture and sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

FDA Statement of Identity

Training Protein Supplement

Suggested/Recommended/Usage/Directions

DOSAGE: Mix 3 slightly rounded scoops with 6-8 ounces of your beverage of choice. On training days take two servings daily one serving within 45 minutes after training and the other serving between meals. On non-training days take one serving daily between meals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Max Protein Chocolate Shake by Universal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)

What’s inside

The Ingredients in Max Protein Chocolate Shake by Universal

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size41.5 Gram(s) Dosage formPowder Servings per container24 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Sodium

Interacts with
205 drugs

125 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs

268 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Phosphorus

138 mg per serving

Calcium

Interacts with
168 drugs

195 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Iron

Interacts with
80 drugs

14 mg per serving

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...

Iron monograph & interactions

Magnesium

Interacts with
295 drugs

25 mg per serving

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Creatine Monohydrate

No known
interactions

2.5 Gram(s) per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Monohydrate monograph & interactions

Taurine

Interacts with
173 drugs

500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions

Protein

30 Gram(s) per serving

Glutamine

Interacts with
50 drugs

1 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

Glutamine monograph & interactions

Other (inactive) ingredients: Max Protein(TM) Blend, Natural and Artificial flavors, Cocoa powder, L-Glutamine, L-Taurine, Lecithin, Guar Gum, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

HelloPharmacist.com · Pharmacist card

Max Protein Chocolate Shake

by Universal · label dated Oct 27, 2014

Scan for the full live report

Known drug interactions: 534 medications — most serious rated major

Active ingredients

Sugar, Sodium, Potassium, Phosphorus, Calcium, Iron, Magnesium, Creatine Monohydrate, Taurine, Protein, Glutamine

Most serious documented interactions

Benserazide, Levodopa — Major (via Magnesium)
Carbidopa — Major (via Magnesium)
Carbidopa, Levodopa — Major (via Magnesium)

Full interaction list, ingredient monographs & live checker: https://hellopharmacist.com/drug-supplement-interactions/supplements/max-protein-chocolate-shake-by-universal-109548
Printed · Educational information only — not medical advice. Confirm against the physical product label and with your pharmacist.

Interaction report

Max Protein Chocolate Shake by Universal Drug Interactions

Max Protein Chocolate Shake — Universal · HelloPharmacist interaction report
Active ingredients: Sugar, Sodium, Potassium, Phosphorus, Calcium, Iron, Magnesium, Creatine Monohydrate, Taurine, Protein, Glutamine
Source label: Oct 27, 2014 · Printed · HelloPharmacist.com
Educational information only — not medical advice. Confirm against the physical product label and with your pharmacist.

HelloPharmacist Interaction Report

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Clinical methodology reviewed by Dr. Brian Staiger, PharmD, BCPS · Last generated Aug 20, 2026

11 active ingredients 7 with known interactions 534 medications covered

Max Protein Chocolate Shake by Universal contains several ingredients with documented interactions with medications.

The most serious interactions involve calcium, which can dramatically reduce levels of two HIV integrase inhibitors—dolutegravir and elvitegravir—by up to 40%, and can cause life-threatening precipitation when given intravenously alongside the antibiotic ceftriaxone. Calcium also moderately interacts with the thyroid drug levothyroxine, the heart rhythm drug sotalol, and several others.

Read the full breakdown — every affected drug type, severity by severity

Sodium in this shake affects multiple drug classes: it can reduce the effectiveness of blood pressure medications (antihypertensives), increase sodium buildup when paired with corticosteroids or certain HIV and bowel-prep drugs, and alter lithium levels dangerously. Potassium interacts moderately with blood pressure drugs (ACE inhibitors and ARBs) and potassium-sparing water pills, raising the risk of dangerously high potassium levels.

Iron reduces absorption of antibiotics (quinolones and tetracyclines), the thyroid drug levothyroxine, the blood pressure drug methyldopa, and several others. Magnesium has a major interaction with the Parkinson's drug levodopa/carbidopa, cutting levodopa levels by 35%, and moderately affects antibiotics, blood pressure drugs, and other classes.

Taurine may heighten the blood-pressure-lowering effect of antihypertensive drugs and can raise lithium levels. Glutamine theoretically may oppose seizure medications, though no human cases are reported.

Altogether, these interactions span 534 individual medications. We could not check phosphorus for interactions.

You'll want to review your specific medications with your doctor or pharmacist before taking this shake, especially if you take any blood pressure, thyroid, antibiotic, HIV, or seizure medication.

Check your own medications below · Editorial policy · How we use AI

Want to check YOUR meds against Max Protein Chocolate Shake?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker

534Drugs

13 Major 413 Moderate 108 Minor

Ingredients driving the most interactions

Magnesium 295

Sodium 205

Taurine 173

Calcium 168

Iron 80

Individual Drug Interactions

The ingredients in Max Protein Chocolate Shake interact with 534 drugs. Click any drug to see the details.

7 of the 11 ingredients in Max Protein Chocolate Shake interact with drugs. Each result below shows which ingredient is responsible. Magnesium Sodium Taurine Calcium Iron Potassium Glutamine

All interactions 534 Major 13 Moderate 413 Minor 108

Showing 121–150 of 534 drugs.

Chlorthalidone, ClonidineClorpres, Combipres

Moderate

Chlorthalidone, Clonidine belongs to Antihypertensive DrugsThiazide Diuretics — the drug categories that interact with this product

How Chlorthalidone, Clonidine interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Chlorthalidone, Clonidine interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Chlorthalidone, Clonidine interaction

CalciumThiazide Diuretics Moderate

Interaction Summary

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full Calcium + Chlorthalidone, Clonidine interaction

ChlorzoxazoneParaflex, Parafon Forte DSC

Moderate

Chlorzoxazone belongs to Skeletal Muscle Relaxants — the drug category that interacts with this product

How Chlorzoxazone interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

MagnesiumSkeletal Muscle Relaxants Moderate

Interaction Summary

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.

Read the full Magnesium + Chlorzoxazone interaction

See the Chlorzoxazone drug page: uses, dosage & side effects

CilazaprilInhibace

Moderate

Cilazapril belongs to Ace Inhibitors (aceis)Antihypertensive Drugs — the drug categories that interact with this product

How Cilazapril interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

PotassiumAce Inhibitors (aceis) Moderate

Interaction Summary

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.

Read the full Potassium + Cilazapril interaction

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Cilazapril interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Cilazapril interaction

CinoxacinCinobac

Moderate

Cinoxacin belongs to Quinolone Antibiotics — the drug category that interacts with this product

How Cinoxacin interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

MagnesiumQuinolone Antibiotics Moderate

Interaction Summary

Magnesium decreases absorption of quinolones.

Read the full Magnesium + Cinoxacin interaction

IronQuinolone Antibiotics Moderate

Interaction Summary

Iron might decrease levels of quinolone antibiotics by reducing their absorption.

Read the full Iron + Cinoxacin interaction

CalciumQuinolone Antibiotics Moderate

Interaction Summary

Calcium seems to reduce the absorption of quinolone antibiotics.

Read the full Calcium + Cinoxacin interaction

CiprofloxacinCiloxan, Cipro, Cipro IV, Cipro XR, Ciprobay, Otiprio

Moderate

Ciprofloxacin belongs to Quinolone Antibiotics — the drug category that interacts with this product

How Ciprofloxacin interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

CalciumQuinolone Antibiotics Moderate

Interaction Summary

Calcium seems to reduce the absorption of quinolone antibiotics.

Read the full Calcium + Ciprofloxacin interaction

MagnesiumQuinolone Antibiotics Moderate

Interaction Summary

Magnesium decreases absorption of quinolones.

Read the full Magnesium + Ciprofloxacin interaction

IronQuinolone Antibiotics Moderate

Interaction Summary

Iron might decrease levels of quinolone antibiotics by reducing their absorption.

Read the full Iron + Ciprofloxacin interaction

See the Ciprofloxacin drug page: uses, dosage & side effects

CisatracuriumNimbex

Moderate

Cisatracurium belongs to Skeletal Muscle Relaxants — the drug category that interacts with this product

How Cisatracurium interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

MagnesiumSkeletal Muscle Relaxants Moderate

Interaction Summary

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.

Read the full Magnesium + Cisatracurium interaction

See the Cisatracurium drug page: uses, dosage & side effects

ClevidipineCleviprex

Moderate

Clevidipine belongs to Antihypertensive Drugs — the drug category that interacts with this product

How Clevidipine interacts with Max Protein Chocolate Shake — through 2 ingredients. Tap an ingredient for the detail:

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Clevidipine interaction

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Clevidipine interaction

ClinafloxacinClinafloxacin

Moderate

Clinafloxacin belongs to Quinolone Antibiotics — the drug category that interacts with this product

How Clinafloxacin interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

CalciumQuinolone Antibiotics Moderate

Interaction Summary

Calcium seems to reduce the absorption of quinolone antibiotics.

Read the full Calcium + Clinafloxacin interaction

IronQuinolone Antibiotics Moderate

Interaction Summary

Iron might decrease levels of quinolone antibiotics by reducing their absorption.

Read the full Iron + Clinafloxacin interaction

MagnesiumQuinolone Antibiotics Moderate

Interaction Summary

Magnesium decreases absorption of quinolones.

Read the full Magnesium + Clinafloxacin interaction

ClobazamFrisium, Onfi, Sympazan

Moderate

Clobazam belongs to Anticonvulsants — the drug category that interacts with this product

How Clobazam interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

GlutamineAnticonvulsants Moderate

Interaction Summary

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Read the full Glutamine + Clobazam interaction

See the Clobazam drug page: uses, dosage & side effects

ClobetasolClobex, Temovate

Moderate

Clobetasol belongs to Corticosteroids — the drug category that interacts with this product

How Clobetasol interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

SodiumCorticosteroids Moderate

Interaction Summary

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.

Read the full Sodium + Clobetasol interaction

See the Clobetasol drug page: uses, dosage & side effects

ClonazepamCeberclon, Klonopin, Rivotril

Moderate

Clonazepam belongs to Anticonvulsants — the drug category that interacts with this product

How Clonazepam interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

GlutamineAnticonvulsants Moderate

Interaction Summary

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Read the full Glutamine + Clonazepam interaction

See the Clonazepam drug page: uses, dosage & side effects

ClonidineCatapres

Moderate

Clonidine belongs to Antihypertensive Drugs — the drug category that interacts with this product

How Clonidine interacts with Max Protein Chocolate Shake — through 2 ingredients. Tap an ingredient for the detail:

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Clonidine interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Clonidine interaction

See the Clonidine drug page: uses, dosage & side effects

ClorazepateTranxene, Tranxene SD, Tranxene T-Tab

Moderate

Clorazepate belongs to Anticonvulsants — the drug category that interacts with this product

How Clorazepate interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

GlutamineAnticonvulsants Moderate

Interaction Summary

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Read the full Glutamine + Clorazepate interaction

See the Clorazepate drug page: uses, dosage & side effects

Cortisone AcetateCortisone Tablets, Cortone

Moderate

Cortisone Acetate belongs to Corticosteroids — the drug category that interacts with this product

How Cortisone Acetate interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

SodiumCorticosteroids Moderate

Interaction Summary

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.

Read the full Sodium + Cortisone Acetate interaction

Cryptenamine, MethyclothiazideDiutensen

Moderate

Cryptenamine, Methyclothiazide belongs to Antihypertensive DrugsThiazide Diuretics — the drug categories that interact with this product

How Cryptenamine, Methyclothiazide interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Cryptenamine, Methyclothiazide interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Cryptenamine, Methyclothiazide interaction

CalciumThiazide Diuretics Moderate

Interaction Summary

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full Calcium + Cryptenamine, Methyclothiazide interaction

CyclobenzaprineCyclobenzaprine, Cycloprine, Flexeril

Moderate

Cyclobenzaprine belongs to Skeletal Muscle Relaxants — the drug category that interacts with this product

How Cyclobenzaprine interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

MagnesiumSkeletal Muscle Relaxants Moderate

Interaction Summary

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.

Read the full Magnesium + Cyclobenzaprine interaction

See the Cyclobenzaprine drug page: uses, dosage & side effects

CyclothiazideAnhydron, Fluidil

Moderate

Cyclothiazide belongs to Thiazide DiureticsAntihypertensive Drugs — the drug categories that interact with this product

How Cyclothiazide interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

CalciumThiazide Diuretics Moderate

Interaction Summary

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full Calcium + Cyclothiazide interaction

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Cyclothiazide interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Cyclothiazide interaction

DantroleneDantrium, Dantrium Intravenous

Moderate

Dantrolene belongs to Skeletal Muscle Relaxants — the drug category that interacts with this product

How Dantrolene interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

MagnesiumSkeletal Muscle Relaxants Moderate

Interaction Summary

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.

Read the full Magnesium + Dantrolene interaction

See the Dantrolene drug page: uses, dosage & side effects

Dantrolene SodiumRyanodex

Moderate

Dantrolene Sodium belongs to Skeletal Muscle Relaxants — the drug category that interacts with this product

How Dantrolene Sodium interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

MagnesiumSkeletal Muscle Relaxants Moderate

Interaction Summary

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.

Read the full Magnesium + Dantrolene Sodium interaction

Darunavir, Cobicistat, Emtricitabine, Tenofovir AlafenamideSymtuza

Moderate

Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide belongs to Bictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) — the drug category that interacts with this product

How Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

IronBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.

Read the full Iron + Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide interaction

MagnesiumBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.

Read the full Magnesium + Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide interaction

CalciumBictegravir/emtricitabine/tenofovir Alafenamide (biktarvy) Moderate

Interaction Summary

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.

Read the full Calcium + Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide interaction

See the Darunavir, Cobicistat, Emtricitabine, Tenofovir Alafenamide drug page: uses, dosage & side effects

DemeclocyclineDeclomycin

Moderate

Demeclocycline belongs to Tetracycline Antibiotics — the drug category that interacts with this product

How Demeclocycline interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

MagnesiumTetracycline Antibiotics Moderate

Interaction Summary

Magnesium decreases absorption of tetracyclines.

Read the full Magnesium + Demeclocycline interaction

CalciumTetracycline Antibiotics Moderate

Interaction Summary

Calcium seems to reduce the absorption of tetracycline antibiotics.

Read the full Calcium + Demeclocycline interaction

IronTetracycline Antibiotics Moderate

Interaction Summary

Iron might decrease levels of tetracycline antibiotics by reducing their absorption.

Read the full Iron + Demeclocycline interaction

See the Demeclocycline drug page: uses, dosage & side effects

DenosumabProlia, XGEVA

Moderate

Denosumab belongs to Denosumab (prolia, Others) — the drug category that interacts with this product

How Denosumab interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

IronDenosumab (prolia, Others) Moderate

Interaction Summary

Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.

Read the full Iron + Denosumab interaction

See the Denosumab drug page: uses, dosage & side effects

DeserpidineHarmonyl

Moderate

Deserpidine belongs to Antihypertensive Drugs — the drug category that interacts with this product

How Deserpidine interacts with Max Protein Chocolate Shake — through 2 ingredients. Tap an ingredient for the detail:

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Deserpidine interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Deserpidine interaction

Deserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte

Moderate

Deserpidine, Hydrochlorothiazide belongs to Antihypertensive DrugsThiazide Diuretics — the drug categories that interact with this product

How Deserpidine, Hydrochlorothiazide interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Deserpidine, Hydrochlorothiazide interaction

CalciumThiazide Diuretics Moderate

Interaction Summary

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full Calcium + Deserpidine, Hydrochlorothiazide interaction

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Deserpidine, Hydrochlorothiazide interaction

Deserpidine, MethyclothiazideEnduronyl, Enduronyl Forte

Moderate

Deserpidine, Methyclothiazide belongs to Antihypertensive DrugsThiazide Diuretics — the drug categories that interact with this product

How Deserpidine, Methyclothiazide interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

SodiumAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.

Read the full Sodium + Deserpidine, Methyclothiazide interaction

CalciumThiazide Diuretics Moderate

Interaction Summary

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Read the full Calcium + Deserpidine, Methyclothiazide interaction

TaurineAntihypertensive Drugs Moderate

Interaction Summary

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.

Read the full Taurine + Deserpidine, Methyclothiazide interaction

DexamethasoneDecadron, Dexone, Dextenza, Dexycu, Hemady, Hexadrol +1 more

Moderate

Dexamethasone belongs to Corticosteroids — the drug category that interacts with this product

How Dexamethasone interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

SodiumCorticosteroids Moderate

Interaction Summary

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.

Read the full Sodium + Dexamethasone interaction

See the Dexamethasone drug page: uses, dosage & side effects

DiazepamDiastat AcuDial, Valium, Valium injection, Valtoco

Moderate

Diazepam belongs to Anticonvulsants — the drug category that interacts with this product

How Diazepam interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

GlutamineAnticonvulsants Moderate

Interaction Summary

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.

Read the full Glutamine + Diazepam interaction

See the Diazepam drug page: uses, dosage & side effects

Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug)K-Phos Neutral

Moderate

Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug) belongs to Potassium-sparing DiureticsSodium-containing Drugs — the drug categories that interact with this product

How Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug) interacts with Max Protein Chocolate Shake — through 3 ingredients. Tap an ingredient for the detail:

MagnesiumPotassium-sparing Diuretics Moderate

Interaction Summary

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.

Read the full Magnesium + Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug) interaction

PotassiumPotassium-sparing Diuretics Moderate

Interaction Summary

Concomitant use increases the risk of hyperkalemia.

Read the full Potassium + Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug) interaction

SodiumSodium-containing Drugs Moderate

Interaction Summary

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.

Read the full Sodium + Dibasic Sodium Phosphate, Monobasic Potassium Phosphate, Monobasic Sodium Phosphate Monohydrate (prescription Drug) interaction

DidanosineVidex, Videx EC

Moderate

Didanosine belongs to Didanosine (videx)Sodium-containing Drugs — the drug categories that interact with this product

How Didanosine interacts with Max Protein Chocolate Shake — through 1 ingredient. Tap an ingredient for the detail:

SodiumDidanosine (videx), Sodium-containing Drugs Moderate

Interaction Summary

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.

Read the full Sodium + Didanosine interaction

See the Didanosine drug page: uses, dosage & side effects

DigoxinDigitek, Lanoxicaps, Lanoxin

Moderate

Digoxin belongs to DigoxinDigoxin (lanoxin) — the drug categories that interact with this product

How Digoxin interacts with Max Protein Chocolate Shake — through 2 ingredients. Tap an ingredient for the detail:

MagnesiumDigoxin Moderate

Interaction Summary

Magnesium salts may reduce absorption of digoxin.

Read the full Magnesium + Digoxin interaction

CalciumDigoxin (lanoxin) Moderate

Interaction Summary

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.

Read the full Calcium + Digoxin interaction

See the Digoxin drug page: uses, dosage & side effects

Each ingredient & the kinds of drugs it affects

For each ingredient in Max Protein Chocolate Shake with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnesium15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B

Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D

Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D

Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B

Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D

Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B

Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D

Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D

Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A

Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B

Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D

Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B

Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B

Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B

Magnesium full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A

Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D

Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C

Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B

Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D

Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D

Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C

Sodium full monograph & interactions

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D

Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D

Taurine full monograph & interactions

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D

Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B

Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B

Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D

Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C

Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B

Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B

Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D

Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B

Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B

Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B

Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B

Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B

Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C

Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C

Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D

Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D

Calcium full monograph & interactions

Iron13 drug types · 80 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.

Likelihood Probable Evidence D

Bisphosphonates

Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D

Denosumab (Prolia, Others)

Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.

Likelihood Possible Evidence D

Dolutegravir (Tivicay)

Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.

Likelihood Probable Evidence B

Integrase Inhibitors

Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.

Likelihood Possible Evidence D

Levodopa

Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.

Likelihood Probable Evidence B

Levothyroxine (Synthroid, Others)

Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence B

Methyldopa (Aldomet)

Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.

Likelihood Probable Evidence B

Mycophenolate Mofetil (Cellcept)

Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.

Likelihood Unlikely Evidence D

Penicillamine (Cuprimine, Depen)

Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.

Likelihood Probable Evidence D

Quinolone Antibiotics

Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D

Tetracycline Antibiotics

Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.

Likelihood Probable Evidence D

Chloramphenicol

Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.

Likelihood Unlikely Evidence D

Iron full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C

Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C

Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C

Potassium full monograph & interactions

Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D

Glutamine full monograph & interactions

The maker

Brand information

Manufacturer and brand details for Max Protein Chocolate Shake, from the product label.

Universal

See all Universal products

Name: Universal Nutrition
City: New Brunswick
State: New Jersey
ZipCode: 08901
Phone Number: 800-872-0101
Web Address: www.universalUSA.com

Pharmacist Counseling Corner

Max Protein Chocolate Shake by Universal: Common Questions

Does Max Protein Chocolate Shake by Universal interact with any medications?

Yes. Based on its ingredients, Max Protein Chocolate Shake has a known interaction with 534 medications, including 13 rated major. Use the checker to see how it interacts with a specific drug.

How can one product interact with so many drugs?

Max Protein Chocolate Shake contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.

Where does this information come from?

The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Does this shake have a lot of sodium in it?

The product facts don't specify the exact sodium amount per serving, so you'd need to check the nutrition label. What we do know is that sodium in this shake can interact with blood pressure medications, corticosteroids, and lithium, so if you take any of those, mention it to your doctor before using this product regularly.

Is creatine safe if I have kidney problems?

The safety data advises caution for people with kidney issues. Creatine should only be used by people with kidney disease under medical supervision. If you have any kidney concerns, talk with your doctor or pharmacist before taking this shake.

Can I take this shake while I'm pregnant?

Some ingredients like calcium, potassium, magnesium, and glutamine are rated likely safe in pregnancy, and iron is typically recommended under prenatal guidance. However, creatine safety in pregnancy has not been established and is best avoided. Talk with your prenatal care provider about whether this shake is right for you and in what amounts.

What does creatine do in this shake?

Creatine monohydrate supports muscle strength and athletic performance, and may help with muscle loss (sarcopenia). It's included to aid recovery and muscle building after exercise.

Can I take this shake if I'm breastfeeding?

Most ingredients—potassium, magnesium, and glutamine—are acceptable at appropriate doses while breastfeeding. However, iron is rated likely unsafe, and creatine and taurine should be avoided or used only with caution. Check with your doctor or pharmacist to confirm the dose is right for you and your baby.

What are taurine and glutamine in here for?

Taurine and glutamine are amino acids that support muscle recovery and protein synthesis. They may help with muscle maintenance and postoperative recovery after intense exercise or injury.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Max Protein Chocolate Shake is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Go deeper

The Full Monographs Behind Max Protein Chocolate Shake’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Iron

Interacts with 80 drugs

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...

Read the full Iron monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →

Sources

Sources & How We Checked

Max Protein Chocolate Shake's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 384 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references

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Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed

See these in context on the Sodium monograph →

Potassium 12 references

McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
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Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Calcium 62 references

Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
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Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
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Decktor DL, Robinson M, Maton PN, et al. Effects of aluminum/magnesium hydroxide and calcium carbonate on esophageal and gastric pH in subjects with heartburn. Am J Ther 1995;2:546-52. PubMed
Simoneau G. Absence of rebound effect with calcium carbonate. Eur J Drug Metab Pharmacokinet 1996;21:351-7. PubMed
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Bourke JF, Mumford R, Whittaker P, et al. The effects of topical calcipotriol on systemic calcium homeostasis in patients with chronic plaque psoriasis. J Am Acad Dermatol 1997;37:929-34.
Gueguen L, Pointillart A. The bioavailability of dietary calcium. J Am Coll Nutr 2000;19:119s-136s. PubMed
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Bania TC, Blaufeux B, Hughes S, et al. Calcium and digoxin vs. calcium alone for severe verapamil toxicity. Acad Emerg Med 2000;7:1089-96. PubMed
Tseng M, Breslow RA, Graubard BI, Ziegler RG. Dairy, calcium, and vitamin D intakes and prostate cancer risk in the National Health and Nutrition Examination Epidemiologic Follow-up Study cohort. Am J Clin Nutr 2005;81:1147-54. PubMed
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Giovannucci E, Liu Y, Stampfer MJ, Willett WC. A prospective study of calcium intake and incident and fatal prostate cancer. Cancer Epidemiol Biomarkers Prev 2006;15:203-10. PubMed
Rocephin (ceftriaxone) and calcium interaction. Pharmacist's Letter / Prescriber's Letter 2007;23(10):231005.
Bolland MJ, Barber PA, Doughty RN, et al. Vascular events in healthy older women receiving calcium supplementation: randomised control trial. BMJ 2008;336:262-6.
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Coburn JW, Mischel MG, Goodman WG, et al. Calcium citrate markedly enhances aluminum absorption from aluminum hydroxide. Am J Kidney Dis. 1991;17(6):708-11. PubMed
Bradley JS, Wassel RT, Lee L, et al. Intravenous ceftriaxone and calcium in the neonate: assessing the risk for cardiopulmonary adverse events. Pediatrics. 2009;123(4):e609-13. PubMed
Kays MB, Overholser BR, Mueller BA, et al. Effects of sevelamer hydrochloride and calcium acetate on the oral bioavailability of ciprofloxacin. Am J Kidney Dis. 2003;42(6):1253-9. PubMed
Neuhofel, A. L., Wilton, J. H., Victory, J. M., Hejmanowsk, L. G., and Amsden, G. W. Lack of bioequivalence of ciprofloxacin when administered with calcium-fortified orange juice: a new twist on an old interaction. J Clin Pharmacol. 2002;42(4):461-466. DOI
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Creatine 86 references

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Taurine 21 references

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Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
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Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Glutamine 11 references

Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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Max Protein Chocolate Shake Ingredients & Drug Interactions

Check Your Meds Against Max Protein Chocolate Shake by Universal

HelloPharmacist Scorecard of Max Protein Chocolate Shake by Universal

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General information

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Max Protein Chocolate Shake by Universal label

The Ingredients in Max Protein Chocolate Shake by Universal

Sugar

Phosphorus

Protein

Max Protein Chocolate Shake by Universal Drug Interactions

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Ingredients driving the most interactions

Individual Drug Interactions

Each ingredient & the kinds of drugs it affects

Magnesium15 drug types · 295 drugs

Sodium7 drug types · 205 drugs

Taurine2 drug types · 173 drugs

Calcium18 drug types · 168 drugs

Iron13 drug types · 80 drugs

Potassium3 drug types · 62 drugs

Glutamine1 drug type · 50 drugs

Brand information

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The Full Monographs Behind Max Protein Chocolate Shake’s Ingredients

Sodium

Potassium

Calcium

Iron

Magnesium

Creatine

Taurine

Glutamine

Sources & How We Checked

The 384 references behind this product’s interaction data