Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Mega Potency Probiotic Acidophilus Ingredients & Drug Interactions

by Vitamin World

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Mega Potency Probiotic Acidophilus is a dietary supplement by Vitamin World with 2 active ingredients. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 23 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Citrus Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Mega Potency Probiotic Acidophilus by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.

This product has 2 active ingredients: citrus pectin and a Proprietary Acidophilus Blend. Citrus pectin is a soluble fiber from citrus fruit peels; acidophilus is a live beneficial bacterium (probiotic) meant to support digestive health.

The capsule also contains gelatin, calcium silicate, and vegetable magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Pectin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestive health and intestinal flora support.
  • We looked for evidence on: Diarrhea, Irritable bowel syndrome (IBS), Gastroesophageal reflux disease (GERD), Gut microbiome, Dysbiosis, Intestinal flora imbalance.
  • The closest evidence on file: Pectin is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: Pectin is rated "Insufficient Reliable Evidence To Rate" for Gastroesophageal reflux disease (GERD), Irritable bowel syndrome (IBS).

Citrus pectin has possibly effective evidence for high cholesterol (hypercholesterolemia). For blood sugar control (impaired glucose tolerance or prediabetes) and radiation exposure, the evidence we hold is insufficient to rate how well it works.

We don't have effectiveness data on file for the Proprietary Acidophilus Blend.

The evidence, ingredient by ingredient Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Citrus pectin from food and typical supplement doses is generally well tolerated. The most common side effects are diarrhea, gas, loose stools, and mild cramps.

Rarely, sensitive people may have allergic reactions, including severe ones. If you're pregnant or breastfeeding, the safety of concentrated pectin supplements hasn't been well studied — talk to your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pectin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 23 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your doctor or pharmacist if you're on digoxin (Lanoxin), lovastatin (Mevacor), or any tetracycline antibiotic — pectin may interfere with how your body absorbs these drugs. No interactions are documented for the Proprietary Acidophilus Blend, but we hold no data on it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with high cholesterol, but the citrus pectin in it can reduce how well digoxin, lovastatin, and tetracycline antibiotics work. If you take any heart, cholesterol, or antibiotic medications, check with your doctor or pharmacist before starting.

It's generally well tolerated, though gas and loose stools can happen.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mega Potency Probiotic Acidophilus, straight from the product label.

Brand Vitamin World
Barcode (UPC) 074312715402
Net contents 100 Rapid Release Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20275
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mega Potency Probiotic Acidophilus by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
UPC/BARCODE
074312715402
IngredientAmount% DV
Citrus Pectin100 mg--
Proprietary Acidophilus Blend0 NP--

Other ingredients: Gelatin, Calcium Silicate, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

**3 billion active cultures per capsule guaranteed at time of manufacture

Vitamin World products are subject to critically stringent quality assurance analysis. Our state-of-the-art laboratory, manufacturing and packaging facilities insure the highest quality nutritional supplements money can buy. Your health & safety are our first priority!

Get healthy.

DIGESTIVE CARE*

3 BILLION ACTIVE CULTURES**

Helps Maintain Healthy Intestinal Balance*

The intestines are one of the principal organs for digestion, so it is important to maintain intestinal health.* Mega Potency Probiotic Acidophilus supports a favorable environment for nutrients, encourages intestinal microflora balance, and promotes the healthy functioning of the intestinal system.*

Intestinal microflora imbalance may lead to inefficient digestion.

Seals/Symbols

QA QUALITY ASSURED

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Precautions

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store unopened container at room temperature. Refrigerate after opening.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PROD. #1540 B1540 11F

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) to three (3) capsules daily, preferably with meals.

Formula

This formula also provides Citrus Pectin.

See for yourself

Mega Potency Probiotic Acidophilus by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mega Potency Probiotic Acidophilus by Vitamin World

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Citrus Pectin

Interacts with
23 drugs
100 mg per serving

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

Citrus Pectin monograph & interactions

Proprietary Acidophilus Blend

0 NP per serving Form: B. lactis, L. bulgaricus, L. salivarius, Lactobacillus acidophilus

Other (inactive) ingredients: Gelatin, Calcium Silicate, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mega Potency Probiotic Acidophilus by Vitamin World Drug Interactions

Want to check YOUR meds against Mega Potency Probiotic Acidophilus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
23Drugs
23 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Mega Potency Probiotic Acidophilus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Citrus Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Mega Potency Probiotic Acidophilus, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Pharmacist Counseling Corner

Mega Potency Probiotic Acidophilus by Vitamin World: Common Questions

Does Mega Potency Probiotic Acidophilus by Vitamin World interact with any medications?
Yes. Based on its ingredients, Mega Potency Probiotic Acidophilus has a known interaction with 23 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mega Potency Probiotic Acidophilus contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The evidence on concentrated pectin supplements during pregnancy and breastfeeding hasn't been well studied. Talk to your doctor or pharmacist about whether it's safe for your situation — they can weigh your individual needs.
What are the side effects?
Most people tolerate citrus pectin well. You might notice diarrhea, gas, loose stools, or mild stomach cramps. Rarely, people sensitive to pectin can have allergic reactions.
Does this actually work?
Citrus pectin has possibly effective evidence for lowering high cholesterol. For blood sugar control or radiation exposure, we don't have enough reliable evidence to say how well it works. We have no effectiveness data for the acidophilus blend.
What is citrus pectin?
It's a soluble fiber extracted from citrus fruit peels. It's used in this supplement as a source of dietary fiber and for its possible cholesterol-lowering effects.
What is acidophilus?
It's a live beneficial bacterium (probiotic) meant to support healthy digestion and gut flora balance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mega Potency Probiotic Acidophilus is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mega Potency Probiotic Acidophilus label
Go deeper

The Full Monographs Behind Mega Potency Probiotic Acidophilus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Mega Potency Probiotic Acidophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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