Interactions on record — worth a quick check against your medications. Based on 3 of 11 ingredients. Check your meds →
Dietary supplement

Mitastone Ingredients & Drug Interactions

by Ayur Earth

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Mitastone is a dietary supplement by Ayur Earth with 11 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 260 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gokshur, Shuddha Shilajit, Yavakshar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Mitastone by Ayur Earth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

Mitastone contains 11 ingredients total. The active ones are gokshur (tribulus), shilajit, barley, and several traditional Ayurvedic herbs—punarnava, pashanbhed, palash pushpa, shwet parpati, varun ghana, sahadev, aparnarg, and lajjalu mool—combined in a proprietary herbal blend.

The tablet also contains inactive ingredients: xanthan gum, maize starch, silicon dioxide, magnesium stearate, and HPMC (a capsule material).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: kidney support and urinary tract health.
  • We looked for evidence on: Kidney stones (nephrolithiasis), Urinary tract infection, Renal function, Electrolyte balance.
  • The closest evidence on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Kidney stones (nephrolithiasis) (Natural Medicines).

Evidence for this product's ingredients is mixed. Gokshur is rated possibly effective for sexual dysfunction, but possibly ineffective for athletic performance; we lack reliable evidence to rate it for benign prostatic hyperplasia.

Barley is rated likely effective for high cholesterol and heart disease prevention. Shilajit's effectiveness isn't established in our data—it's rated insufficient evidence across the conditions we checked (Alzheimer disease, sexual dysfunction, athletic performance, benign prostatic hyperplasia, and osteopenia).

For the other seven ingredients we could not check, no effectiveness data is on file.

The evidence, ingredient by ingredient Tribulus Shilajit Barley

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gokshur is often well tolerated short-term in healthy adults, but long-term safety data are limited. Serious but rare side effects include liver and kidney injury, seizures, and a painful erection disorder; everyday side effects—abdominal pain, nausea, vomiting, diarrhea—occurred at similar rates to placebo in one study.

Shilajit carries a contamination risk: unpurified products may contain heavy metals, so only use purified, tested brands. Rare serious side effects include severe allergic reactions.

Barley is well tolerated as food but contains gluten; concentrated barley supplements haven't been well studied. Most people experience only mild bloating or gas.

All three checked ingredients should be avoided in pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Tribulus Shilajit Barley

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Tribulus, Barley, Shilajit.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 260 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Mitastone, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives)—gokshur may lower your pressure further. Also flag diabetes medications (antidiabetes drugs) because both gokshur and shilajit may boost their sugar-lowering effect and raise low blood sugar risk.

If you take lithium, you need to confirm dosing, as gokshur might increase its levels. And if you take triclabendazole (Egaten) for a parasitic infection, check whether barley in this blend could affect it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Mitastone is used in traditional Ayurvedic practice, but if you take blood pressure medications, diabetes drugs, or lithium, you'll want to check with your doctor or pharmacist before starting it—the interactions are real and could affect how your medications work. The product is generally well tolerated but carries safety gaps for long-term use and pregnancy.

Talk it over with your own healthcare provider to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mitastone, straight from the product label.

Brand Ayur Earth
Barcode (UPC) 689128589972
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 248044
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mitastone by Ayur Earth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
689128589972
IngredientAmount% DV
Proprietary Herbal Blend400 mg--
Gokshur0 NP--
Punarnava0 NP--
Pashanbhed0 NP--
Palash Pushpa0 NP--
Shwet Parpati0 NP--
Varun Ghana0 NP--
Sahadev0 NP--
Aparnarg0 NP--
Shuddha Shilajit0 NP--
Lajjalu Mool0 NP--
Yavakshar0 NP--

Other ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate, HPMC

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Ayurvedic herbs Kidney support Pure Natural Effective

V Vegetarian

Non GMO

May help maintain optimum kidney health, urinary tract functioning, electrolyte balance & eliminate calculi

Formulation with Unrevealed Secrets of Natural Bioenhancer Product of India

Free of dairy & soy

Seals/Symbols

V Vegetarian

ISO Certified Company GMP Good Manufacturing Practice FDA Registered Facility 12251469598

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Direction for Use: As a dietary supplement take 1 tablet twice daily preferably after meals. For better results it should be taken with warm water.

Precautions

Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.

Keep out of reach of children.

Do not use if inner seal is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Batch No. : AT675 Expiry DT. : 09/2020 Neutral Code: MH/PD/AYU/002/10

Storage

Store in a cool dry place away from direct sunlight.

See for yourself

Mitastone by Ayur Earth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mitastone by Ayur Earth

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

400 mg per serving
  • Gokshur
  • › Punarnava
  • › Pashanbhed
  • › Palash Pushpa
  • › Shwet Parpati
  • › Varun Ghana
  • › Sahadev
  • › Aparnarg
  • Shuddha Shilajit
  • › Lajjalu Mool
  • Yavakshar

Other (inactive) ingredients: Xanthan Gum, Maize Starch, Silicon Dioxide, Magnesium Stearate, HPMC. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mitastone by Ayur Earth Drug Interactions

Want to check YOUR meds against Mitastone?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
260Drugs
260 Moderate

Ingredients driving the most interactions

Gokshur 259

Each ingredient & the kinds of drugs it affects

For each ingredient in Mitastone with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gokshur3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D

Shuddha Shilajit1 drug type · 86 drugs

Antidiabetes Drugs

Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Most human and animal research shows that shilajit can decrease fasting plasma glucose levels. In an animal model, shilajit 100 mg per kg daily enhanced the glucose-lowering ability of both glibenclamide and metformin when given in combination over a 4 week period. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D

Yavakshar1 drug type · 1 drug

Triclabendazole (Egaten)

Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Mitastone, from the product label.

Ayur Earth

See all Ayur Earth products
Name
U4LIFE, LLC. d.b.a. Ayur Earth
Street Address
PO Box #5
City
Edgewater
State
NJ
ZipCode
07020
Web Address
www.ayurearth.com
Pharmacist Counseling Corner

Mitastone by Ayur Earth: Common Questions

Does Mitastone by Ayur Earth interact with any medications?
Yes. Based on its ingredients, Mitastone has a known interaction with 260 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mitastone contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Mitastone safe during pregnancy?
No. Gokshur and shilajit are rated possibly unsafe or unsafe in pregnancy, and their safety is not established. Concentrated barley supplements also lack safety data in pregnancy. You should avoid this product if you're pregnant and talk with your doctor or pharmacist about any alternatives.
Can I take Mitastone while breastfeeding?
No. All three of the checked active ingredients—gokshur, shilajit, and barley—should be avoided while breastfeeding due to lack of reliable safety information. Discuss other options with your doctor or pharmacist.
What is gokshur used for in this product?
Gokshur (tribulus) is rated possibly effective for sexual dysfunction. It's also used in traditional medicine for urinary and reproductive health, though evidence is limited for other uses like benign prostatic hyperplasia.
Does barley in Mitastone contain gluten?
Yes, barley naturally contains gluten. If you have celiac disease or gluten sensitivity, you should avoid this product or check with your doctor first.
What side effects might I experience from Mitastone?
Most common are mild digestive complaints—bloating, gas, nausea, or cramping—similar to what some people get from placebo. Rare serious side effects from the checked ingredients include liver or kidney injury, seizures, or severe allergic reactions. Stop and seek help immediately if you notice unusual symptoms.
Why can't you check seven of the ingredients for drug interactions?
We don't hold monograph data for punarnava, pashanbhed, palash pushpa, shwet parpati, varun ghana, sahadev, aparnarg, or lajjalu mool. That doesn't mean they're safe to mix with your medications—it means the information simply isn't in our database. Check with your pharmacist about any concerns.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mitastone label
Sources

Sources & How We Checked

Mitastone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 33 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Shilajit 8 references
  1. Sadeghi SMH, Hosseini Khameneh SM, Khodadoost M, et al. Efficacy of momiai in tibia fracture repair: A randomized double-blinded placebo-controlled clinical trial. J Altern Complement Med 2020;26(6):521-528.
  2. Losa F, Deidda M, Firinu D, Martino MLD, Barca MP, Giacco SD. Exercise-induced anaphylaxis with an Ayurvedic drug as cofactor: A case report. World J Clin Cases 2019;7(5):623-627. PubMed
  3. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia 2010;42(1):48-56. PubMed
  4. Stavropoulos K, Sotiriadis A, Patoulias D, et al. Pseudohyperaldosteronism due to mumijo consumption during pregnancy: a licorice-like syndrome. Gynecol Endocrinol 2018;34(12):1019-1021. PubMed
  5. Ghezelbash B, Shahrokhi N, Khaksari M, Ghaderi-Pakdel F, Asadikaram G. Hepatoprotective effects of shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Horm Mol Biol Clin Investig 2020;41(1):/j/hmbci. PubMed
  6. Ghezelbash B, Shahrokhi N, Khaksari M, Asadikaram G, Shahrokhi M, Shirazpour S. Protective roles of shilajit in modulating resistin, adiponectin, and cytokines in rats with non-alcoholic fatty liver disease. Chin J Integr Med 2022;28(6):531-537. PubMed
  7. Jafari M, Forootanfar H, Ameri A, et al. Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains. Pak J Pharm Sci 2019;32(5):2167-2173. DOI
  8. Trivedi NA, Mazumdar B, Bhatt JD, Hemavathi KG. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats. Ind. J. Pharmacol. 2004; 36(6):373-376.

See these in context on the Shilajit monograph →

Barley 15 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Fernandez-Anaya S, Crespo JF, Rodriguez JR, et al. Beer anaphylaxis. J Allergy Clin Immunol 1999;103:959-60.
  3. Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
  4. Ferre, I., Giraldez, F. J., Alvarez-Bujidos, M. L., and Mantecon, A. R. Influence of barley supplement on plasma concentration of triclabendazole metabolites in sheep. Vet.Rec. 11-22-1997;141(21):549-551. PubMed
  5. Curioni, A., Santucci, B., Cristaudo, A., Canistraci, C., Pietravalle, M., Simonato, B., and Giannattasio, M. Urticaria from beer: an immediate hypersensitivity reaction due to a 10- kDa protein derived from barley. Clin Exp Allergy 1999;29(3):407-413. PubMed
  6. Fernandez-Anaya, S., Crespo, J. F., Rodriguez, J. R., Daroca, P., Carmona, E., Herraez, L., and Lopez-Rubio, A. Beer anaphylaxis. J Allergy Clin Immunol. 1999;103(5 Pt 1):959-960.
  7. Cronin, E. Contact dermatitis from barley dust. Contact Dermatitis 1979;5(3):196. PubMed
  8. Block, G., Tse, K. S., Kijek, K., Chan, H., and Chan-Yeung, M. Baker's asthma. Studies of the cross-antigenicity between different cereal grains. Clin Allergy 1984;14(2):177-185.
  9. van Ketel, W. G. Immediate type allergy to malt in beer. Contact Dermatitis 1980;6(4):297-298. PubMed
  10. Ellis, H. J., Doyle, A. P., Day, P., Wieser, H., and Ciclitira, P. J. Demonstration of the presence of coeliac-activating gliadin-like epitopes in malted barley. Int Arch Allergy Immunol. 1994;104(3):308-310. PubMed
  11. Vidal, C. and Gonzalez-Quintela, A. Food-induced and occupational asthma due to barley flour. Ann Allergy Asthma Immunol. 1995;75(2):121-124.
  12. Gutgesell, C. and Fuchs, T. Contact urticaria from beer. Contact Dermatitis 1995;33(6):436-437. PubMed
  13. Baker, P. G. and Read, A. E. Oats and barley toxicity in coeliac patients. Postgrad.Med J 1976;52(607):264-268. PubMed
  14. Nakase, M., Usui, Y., Alvarez-Nakase, A. M., Adachi, T., Urisu, A., Nakamura, R., Aoki, N., Kitajima, K., and Matsuda, T. Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy 1998;53(46 Suppl):55-57. PubMed
  15. Pereira, F., Rafael, M., and Lacerda, M. H. Contact dermatitis from barley. Contact Dermatitis 1998;39(5):261-262. PubMed

See these in context on the Barley monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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