Monster Creatine Watermelon Ingredients & Drug Interactions
by CytoSport
What is this page for?
First and foremost: checking Monster Creatine Watermelon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Monster Creatine Watermelon is a dietary supplement by CytoSport with 3 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 220 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Monster Creatine Watermelon by CytoSport
Ask about any prescription or over-the-counter medication and we check it for interactions with Monster Creatine Watermelon by CytoSport — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Monster Creatine Watermelon by CytoSport
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This powder has 3 active ingredients: sodium, potassium, and creatine (sold as Creapure). Sodium and potassium are electrolytes — your body needs them for nerve and muscle function, but the amounts matter, especially if you take certain medications.
Creapure is a purified form of creatine, an amino acid that plays a role in muscle energy production. The rest is inactive ingredients — flavoring, sweeteners (sucralose and acesulfame potassium), citric acid for tang, and carmine for color.
Does it work?
Moderate evidence
The data we hold shows creatine is possibly effective for sarcopenia (age-related muscle loss), cerebral creatine deficiency syndromes, muscle strength, and athletic performance. It's possibly ineffective for Huntington disease and osteopenia.
Sodium and potassium are essential nutrients, but their usefulness beyond normal dietary intake isn't established in the data we hold for this product — they're here as electrolytes to support hydration during and after exercise, which is standard for sports drinks.
How safe is it?
Well-documented data
Creatine is generally well tolerated in healthy adults, though common side effects include dehydration, diarrhea, stomach upset, muscle cramps, and water retention. Rare serious concerns raised in case reports are kidney inflammation, kidney insufficiency, and muscle breakdown (rhabdomyolysis), though clinical studies haven't confirmed a broad pattern.
Sodium at normal dietary amounts is fine, but too much is linked to high blood pressure and heart strain — avoid sodium supplements or very high intake without medical advice. Potassium from food is safe, but supplements can cause dangerously high blood levels in people with kidney disease.
For pregnancy: creatine safety hasn't been established, so it's best avoided. Sodium is likely safe in pregnancy but possibly unsafe in lactation.
Potassium is likely safe in both. Talk with your doctor or pharmacist about what's right for you.
Meds to double-check
Moderate interaction found
Check before you take this if you use blood pressure or heart drugs — especially ACE inhibitors, angiotensin receptor blockers, potassium-sparing water pills, corticosteroids, lithium, didanosine, or tolvaptan. All carry a moderate risk of electrolyte imbalance from the sodium and potassium in this product.
Also flag sodium-containing drugs and sodium phosphate bowel prep if you use them.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a sports drink powder with creatine and electrolytes — reasonable for an athlete wanting muscle support and hydration. But if you take blood pressure meds, heart medications, diuretics, kidney drugs, or lithium, the sodium and potassium here could be a problem.
Check your exact medications with your doctor or pharmacist before starting, and avoid it altogether during pregnancy unless your doctor says otherwise.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Monster Creatine Watermelon, straight from the product label.
| Brand | CytoSport |
|---|---|
| Barcode (UPC) | 660726803806 |
| Net contents | 17.6 oz.; 1.1 lbs; 500 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2015 |
| DSLD ID | 50346 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Monster Creatine Watermelon by CytoSport, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 {Calories} | -- |
| Total Carbohydrates | 4 Gram(s) | 1% |
| Sodium | 80 mg | 3% |
| Potassium | 210 mg | 6% |
| Creapure | 5 Gram(s) | -- |
Other ingredients: Maltodextrin, Citric Acid, Potassium Citrate, Malic Acid, Natural and Artificial flavors, Sodium Citrate, Acesulfame Potassium, Sucralose, Carmine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
DIRECTIONS & USE Mix 1 scoop (10g) with 8 fl-oz of water or beverage of choice. MONSTER CREATINE Supplement can be used before or after workouts. Recommended Creatine Loading Dose: For first 5-7 days of use take 1 serving (10g) with 8 fl-oz of water (or beverage of choice) four times daily. Recommended Creatine Maintenance Dose: After loading phase consume 1 serving (10g) with 8 fl-oz of water (or beverage of choice) once daily for 5-8 weeks. Mix 1 scoop (10g) Into 8 FL-OZ OF WATER OR BEVERAGE OF CHOICE {CONTAINER} {SCOOP} X1 (10g) 8FL-OZ OF WATER OR BEVERAGE OF CHOICE
General Statements
When taking any creatine supplement it is important to stay well hydrated. This product complements a smart eating and hydration plan that, in conjunction with a balanced exercise program, may contribute to weight management and recovery from exercise.
NSF screens supplements for more than 200 substances banned by most major athletic organizations. The main components of NSF’s certification program are label claim review, a toxicology review to certify the formulation and contaminant review to ensure against contaminants. nsfsport.com
NUTRIENT SUMMARY WHAT ARE YOU GETTING? CHECK THIS OUT...
Helps fuel muscles to enhance your workout and to help build strength and lean muscle. Works at the cellular level to promote strength, power and endurance during your workout. Helps regenerate ATP to help fuel muscular contractions.
> PREPARE TRAIN > RECOVER
NATURALLY AND ARTIFICIALLY FLAVORED
Seals/Symbols
NSF Certified for Sport www.nsf.org
CYTOSPORT MONSTER SERIES
PLEASE RECYCLE
Formulation
FREE OF BANNED SUBSTANCES
GLUTEN FREE
Brand IP Statement(s)
Creapure Patented pure creatine monohydrate
Monster
Creapure is a licensed registered trademark of AlzChem Trostberg GmbH.
2015 CytoSport, Inc.
Monster IS SPORTS NUTRITION THAT STANDS FOR: TRUTH POWDER LIFE WHAT DO YOU STAND FOR? We stand for truth, power and unyielding support of athletic lifestyles. This is our unwavering commitment to quality. A symbol to carry and support you before, during and after training or competition. stands for TRUTH: fully disclosed nutritional ingredients and no proprietary blends; POWER: efficacious formulations that enhance your performance; LIFE: inspiration you need to achieve your lifelong goals. Because truth is power, power is performance and performance changes lives.
Formula
5 G CREAPURE CREATINE MONOHYDRATE
FDA Statement of Identity
CREATINE SUPPLEMENT MIX
General
L-80380-REV01.03/15 62542 S1097749-01
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Monster Creatine Watermelon by CytoSport label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Monster Creatine Watermelon by CytoSport
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size10 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsPotassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsCreapure
No knowninteractions
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...
Creapure monograph & interactionsOther (inactive) ingredients: Maltodextrin, Citric Acid, Potassium Citrate, Malic Acid, Natural and Artificial flavors, Sodium Citrate, Acesulfame Potassium, Sucralose, Carmine. These complete the product’s ingredient list but are not active constituents.
Monster Creatine Watermelon by CytoSport Drug Interactions
HelloPharmacist Interaction Report
Monster Creatine Watermelon by CytoSport contains sodium and potassium, both of which interact with medications.
Sodium is the more serious concern here — it can reduce how well blood pressure drugs work, and it carries a moderate risk of dangerously high sodium levels (hypernatremia) if you're also taking corticosteroids, lithium, didanosine, sodium phosphate bowel prep, tolvaptan, or other sodium-containing drugs.
Read the full breakdown — every affected drug type, severity by severity
Potassium also poses a moderate risk of dangerously high potassium levels (hyperkalemia) when combined with potassium-sparing water pills, ACE inhibitors, or angiotensin receptor blockers — drugs commonly prescribed for high blood pressure and heart conditions. The creatine (Creapure) itself has no documented interactions with medications.
Altogether, these interactions span 220 individual medications. Because sodium and potassium are in nearly every medication and many foods, the real issue is whether the amounts in this product tip you over safe limits when added to what you're already taking.
If you're on any blood pressure, heart, kidney, or psychiatric medication, run your specific drugs through the interaction checker below before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Monster Creatine Watermelon?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Monster Creatine Watermelon interact with 220 drugs. Click any drug to see the details.
2 of the 3 ingredients in Monster Creatine Watermelon interact with drugs. Each result below shows which ingredient is responsible. Sodium Potassium
AcebutololRhotral, Sectral
How Acebutolol interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Amiloride interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Amiloride, Hydrochlorothiazide interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Amlodipine Besylate, Benazepril interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlorthalidone interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan, Chlorthalidone interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan, Chlorthalidone interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Beclomethasone Dipropionate interactionBenazeprilLotensin
How Benazepril interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Monster Creatine Watermelon — through 2 ingredients. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril, Hydrochlorothiazide interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Monster Creatine Watermelon — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Benzthiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Monster Creatine Watermelon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Monster Creatine Watermelon, from the product label.
Monster Creatine Watermelon by CytoSport: Common Questions
Does Monster Creatine Watermelon by CytoSport interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does creatine actually help with muscle and athletic performance?
Is it safe to take this while pregnant or breastfeeding?
What are the most common side effects?
Is this okay if I have kidney disease?
Why does a sports drink need sodium and potassium?
Will this interfere with my blood pressure or heart medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Monster Creatine Watermelon is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Monster Creatine Watermelon’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographPotassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph → Herb & supplement monographCreatine
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...
Read the full Creatine monograph →Sources & How We Checked
Monster Creatine Watermelon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 136 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
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