Major interaction on record — check this product against your medications before combining. Based on 7 of 9 ingredients. Check your meds →
Dietary supplement

MultiGreens Ingredients & Drug Interactions

by Young Living Essential Oils

Capsule Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

MultiGreens is a dietary supplement by Young Living Essential Oils with 9 active ingredients. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 1,495 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Eleuthero, Alfalfa, Spirulina. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of MultiGreens by Young Living Essential Oils

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 14 active ingredients.
  • “Amino Acid Complex” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Proprietary MultiGreens Blend” is a proprietary blend — the label gives one combined amount (1.28 Gram(s)) without saying how much of each component you get.
  • “MultiGreens Oil Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

MultiGreens contains 14 active ingredients. The amino acids L-arginine, L-tyrosine, choline, and L-cysteine form the protein-building foundation.

Eleuthero (Siberian ginseng), spirulina blue-green algae, barley grass juice, alfalfa, and Pacific kelp bring plant concentrates and minerals. The product also includes a proprietary MultiGreens Blend and an oil blend with rosemary, lemon, lemongrass, and lemon balm (melissa), plus bee pollen for additional nutrients.

The only inactive ingredient listed is gelatin, which forms the capsule shell.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: natural energizing greens and vital nutrients.
  • We looked for evidence on: energy and vitality, general wellness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for MultiGreens' ingredients is mixed. Barley shows Likely Effective data for lowering cholesterol and supporting heart health.

Lemon balm is Possibly Effective for cold sores and stress. L-tyrosine is Effective for phenylketonuria (PKU) and Possibly Effective for cognitive function and memory.

Eleuthero is Possibly Effective for genital herpes and spirulina is Possibly Effective for high blood pressure. Most other claimed uses — including athletic performance, various aspects of cognitive decline, diabetes support, and many others — carry ratings of Insufficient Reliable Evidence or Possibly Ineffective.

The data we hold does not establish that this blend works as a general wellness supplement.

The evidence, ingredient by ingredient Choline Bee Pollen Eleuthero Blue-green Algae Barley Alfalfa Laminaria

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 12 of the 14 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 14 of 14.
  • General safety write-ups exist for 14 of 14.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most individual ingredients are generally well tolerated in the short term, but important cautions apply. L-arginine can lower blood pressure and requires medical supervision for self-treatment use.

Bee pollen can trigger serious allergic reactions, especially in people with pollen allergies, and carries a rare risk of acute hepatitis. Pacific kelp varies widely in iodine and arsenic content; excess iodine can affect the thyroid, and arsenic buildup has been documented.

Eleuthero is generally tolerated short-term but may cause nervousness, anxiety, or elevated blood pressure in some users, and long-term safety is not well studied. Spirulina can be contaminated with toxins or heavy metals depending on its source.

Common side effects across ingredients include abdominal discomfort, bloating, diarrhea, nausea, headache, and dizziness. Rosemary oil and lemongrass oil should not be used in concentrated form without caution, and undiluted rosemary oil may cause seizures.

Side effects, ingredient by ingredient Choline Bee Pollen Eleuthero Blue-green Algae Barley Alfalfa Laminaria

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 14 of the 14 matched ingredients can interact with medications — Alfalfa, Bee Pollen, Rosemary, Choline, Lemon Balm, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 1,496 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before adding MultiGreens, double-check with your doctor or pharmacist if you take any of these: blood thinners (warfarin, antiplatelet drugs, anticoagulants) — alfalfa may reduce warfarin's effect and several ingredients increase bleeding risk; blood pressure medications (ACE inhibitors, ARBs, antihypertensive drugs) — L-arginine can add to their effects and cause low blood pressure; diabetes drugs — multiple ingredients may lower blood glucose further; thyroid medications or antithyroid drugs — Pacific kelp's iodine and lemon balm may interfere; potassium-sparing diuretics — L-arginine and Pacific kelp can raise potassium levels; CNS depressants (sedatives, sleep aids) — lemon balm may enhance their effects; and contraceptive or hormone therapy drugs — alfalfa's phytoestrogens may reduce their effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

MultiGreens is a multi-ingredient botanical and amino acid blend best suited for people interested in general nutritional support, though solid evidence of benefit is limited to a few ingredients (barley for cholesterol, lemon balm for stress). Anyone taking blood thinners, diabetes medications, blood pressure drugs, thyroid medications, or CNS depressants should talk with their doctor or pharmacist before starting, since documented interactions exist.

People with pollen allergies should be especially cautious because of bee pollen's allergy risk. If you have concerns about iodine intake or thyroid function, discuss Pacific kelp's variable iodine content with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 14 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MultiGreens, straight from the product label.

Brand Young Living Essential Oils
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2019
DSLD ID 208413
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MultiGreens by Young Living Essential Oils, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
40
IngredientAmount% DV
L-Arginine0 NP--
L-Tyrosine0 NP--
Choline82 mg15%
Bee Pollen0 NP--
L-Cysteine0 NP--
Eleuthero0 NP--
Amino Acid Complex0 NP--
Spirulina0 NP--
Proprietary MultiGreens Blend1.28 Gram(s)--
Barley (Hordeum vulgare) grass juice concentrate0 NP--
Alfalfa0 NP--
Pacific Kelp0 NP--
MultiGreens Oil Blend0 NP--
Rosemary Oil0 NP--
Lemon Oil0 NP--
Lemongrass Oil0 NP--
Melissa Oil0 NP--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Energizing greens + revitalizing oils

Formulated by D. Gary Young

Formula

With Melissa Oil

MultiGreens is a natural, sustainable energy source with An invigorating blend of greens that increase vitality Nutrient-dense bee pollen A purifying essential oil blend to increase assimilation An excellent source of choline, critical for energy production

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 3 capsules 2 times daily.

Storage

Storage: Keep in a cool, dry place. Do not expose to excessive heat or direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

MultiGreens by Young Living Essential Oils label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MultiGreens by Young Living Essential Oils

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Choline

Interacts with
16 drugs
82 mg per serving Form: Choline Bitartrate

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Proprietary MultiGreens Blend

1.28 Gram(s) per serving

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

MultiGreens by Young Living Essential Oils Drug Interactions

Want to check YOUR meds against MultiGreens?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,495Drugs
2 Major 1,452 Moderate 41 Minor

Ingredients driving the most interactions

Eleuthero 1,140
Alfalfa 583
Spirulina 327
Choline 16

Each ingredient & the kinds of drugs it affects

For each ingredient in MultiGreens with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Eleuthero10 drug types · 1,140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that a constituent of eleuthero, dihydroxybenzoic acid, appears to inhibit platelet aggregation. Concomitant use with anticoagulant or antiplatelet drugs might increase the risk of bleeding. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Animal research suggests that certain constituents of eleuthero have hypoglycemic activity in both healthy and diabetic animals. A small study in adults with type 2 diabetes also shows that taking eleuthero for 3 months can lower blood glucose levels. However, one very small study in healthy individuals shows that taking powdered eleuthero 3 grams, 40 minutes prior to a 75-gram oral glucose tolerance test, significantly increases postprandial blood glucose levels when compared with placebo. These contradictory findings might be due to patient-specific variability and variability in active ingredient ratios.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggest that standardized extracts of eleuthero inhibit CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2C9. This effect has not been reported in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Eleuthero might increase serum digoxin levels and increase the risk of side effects.
In one case report, a 74-year-old male who was stabilized on digoxin presented with an elevated serum digoxin level after starting an eleuthero supplement, without symptoms of toxicity. After stopping the supplement, serum digoxin levels returned to normal. It is not clear whether this was due to a pharmacokinetic interaction or to interference with the digoxin assay. Although the product was found to be free of digoxin and digitoxin, it was not tested for other contaminants.

Likelihood Unlikely Evidence D
Immunosuppressants

Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Animal and in vitro research shows that eleuthero extracts have immunomodulatory effects, including increasing cellular and humoral activity.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
In vitro research suggests that eleuthero can inhibit the multi-drug transporter protein, P-glycoprotein. However, it is too soon to tell if this is clinically important. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2D6. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP2D6 drug metabolism.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP3A4. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP3A4 drug metabolism.

Likelihood Unlikely Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
In vitro research suggests that eleuthero inhibits OATP2B1, which might reduce the bioavailability of oral drugs that are substrates of OATP2B1. Due to the weak inhibitory effect identified in this study, this interaction is not likely to be clinically significant.

Likelihood Possible Evidence D

Alfalfa6 drug types · 583 drugs

Warfarin (Coumadin)

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.

Likelihood Possible Evidence D

Spirulina3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D
Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D

Pacific Kelp6 drug types · 69 drugs

Ace Inhibitors (Aceis)

Theoretically, laminaria might increase the risk of hyperkalemia when taken with ACEIs.
Laminaria contains potassium.

Likelihood Possible Evidence D
Amiodarone (Cordarone)

Theoretically, combining laminaria with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with laminaria supplements, some of which may contain as much as 1000 mcg iodine, might increase the risk of adverse effects from iodine, including altered thyroid function.

Likelihood Possible Evidence D
Antithyroid Drugs

Due to its iodine content, laminaria might alter the effects of antithyroid drugs.
Some laminaria supplements contain up to 1000 mcg of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking laminaria could theoretically alter the effects of antithyroid drugs.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, laminaria might increase the risk of hyperkalemia, which could increase the effects and adverse effects of digoxin.
Laminaria contains potassium.

Likelihood Possible Evidence D
Potassium-Sparing Diuretics

Theoretically, laminaria might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Laminaria contains potassium.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, laminaria might alter the effects of thyroid hormone.
Some laminaria supplements contain up to 1000 mcg of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking laminaria could theoretically alter the effects of thyroid hormone.

Likelihood Possible Evidence D

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D

Bee Pollen1 drug type · 2 drugs

Warfarin (Coumadin)

There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.

Likelihood Possible Evidence D

Barley (Hordeum vulgare) grass juice concentrate1 drug type · 1 drug

Triclabendazole (Egaten)

Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for MultiGreens, from the product label.

Young Living Essential Oils

See all Young Living Essential Oils products
Name
Young Living Essential Oils
City
Lehi
State
UT
ZipCode
84043
Phone Number
1-800-371-2928
Pharmacist Counseling Corner

MultiGreens by Young Living Essential Oils: Common Questions

Does MultiGreens by Young Living Essential Oils interact with any medications?
Yes. Based on its ingredients, MultiGreens has a known interaction with 1,495 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MultiGreens contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take MultiGreens if I'm on warfarin or another blood thinner?
No — not without talking to your doctor first. Alfalfa in this product carries a Major interaction with warfarin because its high vitamin K content can reduce warfarin's blood-thinning effect. Several other ingredients also have Moderate interactions with blood thinners. Your doctor or pharmacist needs to review this product and your specific medication before you use it.
Does this product really help with energy and focus?
The ingredients in MultiGreens have mixed evidence. L-tyrosine is Possibly Effective for cognitive function and memory, and lemon balm is Possibly Effective for stress. However, most other uses claimed for such products — athletic performance, general energy, age-related cognitive decline — either have insufficient evidence or are rated Possibly Ineffective in the data we hold.
What's bee pollen in this product for?
Bee pollen is included as a nutrient-dense ingredient, but the evidence for its effectiveness is sparse — the data shows Insufficient Evidence for most conditions. More importantly, bee pollen can trigger serious allergic reactions in people sensitive to pollen, especially those allergic to ragweed or related plants. If you have seasonal allergies, talk to your doctor before taking this product.
Is it safe to take while pregnant or breastfeeding?
Several ingredients raise concerns. Alfalfa, bee pollen, eleuthero, lemongrass, lemon balm, and rosemary have insufficient or unsafe ratings for pregnancy. Pacific kelp is rated Possibly to Likely Unsafe in pregnancy due to iodine affecting fetal thyroid development. Because this is a multi-ingredient product with mixed safety data, talk with your doctor or pharmacist before use if you're pregnant or nursing.
What side effects might I experience?
Common side effects reported across ingredients include abdominal discomfort, bloating, diarrhea, nausea, headache, and dizziness. L-arginine may lower blood pressure. Bee pollen can cause allergic reactions. Eleuthero may cause nervousness or elevated blood pressure in some people. If you experience any concerning symptoms, stop and contact your healthcare provider.
Is this product tested for heavy metals or contaminants?
The product facts don't specify testing details. Spirulina and Pacific kelp can accumulate heavy metals and toxins from their growing environment, and quality varies between batches. If you're concerned about contaminant testing, contact the manufacturer directly or ask your pharmacist to help you identify tested alternatives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MultiGreens is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MultiGreens label
Go deeper

The Full Monographs Behind MultiGreens’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Herb & supplement monograph

Bee Pollen

Interacts with 2 drugs

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...

Read the full Bee Pollen monograph →
Herb & supplement monograph

Eleuthero

Interacts with 1,140 drugs

Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence behind these uses is limited and mixed, so...

Read the full Eleuthero monograph →
Herb & supplement monograph

Blue-green Algae

Interacts with 327 drugs

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...

Read the full Blue-green Algae monograph →
Herb & supplement monograph

Barley

Interacts with 1 drug

Barley is a nutritious whole grain that is a good source of soluble fiber called beta-glucan, which has solid evidence for modestly lowering LDL ('bad') cholesterol when eaten regularly. It...

Read the full Barley monograph →
Herb & supplement monograph

Alfalfa

Interacts with 583 drugs

Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...

Read the full Alfalfa monograph →
Herb & supplement monograph

Laminaria

Interacts with 69 drugs

Laminaria is a type of brown seaweed (kelp) that is very rich in iodine and is also used in medical settings as a natural cervical dilator. Because its iodine content can be high and variabl...

Read the full Laminaria monograph →
Sources

Sources & How We Checked

MultiGreens's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 239 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-arginine 66 references
  1. Sapienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
  2. Clarkson P, Adams MR, Powe AJ, et al. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults. J Clin Invest 1996;97:1989-94. PubMed
  3. Tenenbaum A, Fisman EZ, Motro M. L-arginine: Rediscovery in progress. Cardiology 1998;90:153-9.
  4. Brittenden J, Park KGM, Heys SD, et al. L-Arginine stimulates host defenses in patients with breast cancer. Surgery 1994;115:205-12.
  5. Korting GE, Smith SD, Wheeler MA, et al. A randomized double-blind trial of oral L-arginine for treatment of interstitial cystitis. J Urol 1999;161:558-65. DOI
  6. Rector TS, Bank AJ, Mullen KA, et al. Randomized, double-blind, placebo-controlled study of supplemental oral L-arginine in patients with heart failure. Circulation 1996;93:2135-41.
  7. Siani A, Pagano E, Iacone R, et al. Blood pressure and metabolic changes during dietary L-arginine supplementation in humans. Am J Hypertens 2000;13:547-51. PubMed
  8. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  9. Wallace AW, Tom WL. Interaction of L-arginine and phosphodiesterase inhibitors in vasodilation of the porcine internal mammary artery. Anesth Analg 2000;90:840-6. DOI
  10. Huynh NT, Tayek JA. Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation. J Am Coll Nutr 2002;21:422-7.. PubMed
  11. Staff AC, Berge L, Haugen G, et al. Dietary supplementation with L-arginine or placebo in women with pre-eclampsia. Acta Obstet Gynecol Scand 2004;83:103-7.
  12. Resnick DJ, Softness B, Murphy AR, et al. Case report of an anaphylactoid reaction to arginine. Ann Allergy Asthma Immunol 2002;88:67-8. PubMed
  13. Anon. Arginine hydrochloride injection (marketed as R-Gene 10). FDA Drug Safety Newsletter 2009;2(2):16-18. Available at: www.fda.gov/Drugs/DrugSafety/DrugSafetyNewsletter/default.htm.
  14. Higashi Y, Oshima T, Sasaki S, et. al. Angiotensin-converting enzyme inhibition, but not calcium antagonism, improves a response of the renal vasculature to L-arginine in patients with essential hypertension. Hypertension. 1998 Jul;32(1):16-24.
  15. Facchinetti, F., Longo, M., Piccinini, F., Neri, I., and Volpe, A. L-arginine infusion reduces blood pressure in preeclamptic women through nitric oxide release. J Soc Gynecol.Investig. 1999;6(4):202-207. DOI
  16. de Gouw, H. W., Verbruggen, M. B., Twiss, I. M., and Sterk, P. J. Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. Thorax 1999;54(11):1033-1035. PubMed
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See these in context on the Blue-green Algae monograph →

Barley 15 references
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Alfalfa 32 references
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Laminaria 9 references
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  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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See these in context on the Laminaria monograph →

Rosemary 20 references
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Lemon 2 references
  1. Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
  2. Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed

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Lemongrass 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Li CC, Yu HF, Chang CH, Liu YT, Yao HT. Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats. J Food Drug Anal 2018;26(1):432-8. PubMed

See these in context on the Lemongrass monograph →

Lemon Balm 12 references
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  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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