Major interaction on record — check this product against your medications before combining. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Nanoemulsified Noto Bravi Ingredients & Drug Interactions

by Quicksilver Scientific

Liquid Category: Botanical With Nutrients
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Nanoemulsified Noto Bravi is a dietary supplement by Quicksilver Scientific with 5 active ingredients. Its ingredients are commonly taken for bleeding and bruising, heart and circulation health, high blood pressure.Based on those ingredients, 420 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Cereboost American Ginseng (Panax quinquefolius) root extract, Ginseng Plus Panax notoginseng root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Nanoemulsified Noto Bravi by Quicksilver Scientific

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (225 mg) without saying how much of each component you get.

This product contains 5 active ingredients in liquid form. The core components are Panax notoginseng (also called noto ginseng) and Cereboost American ginseng, two herbal extracts traditionally used in cardiovascular and immune support; LifeFlower Erigeron breviscapus, an herb extract; and Epimedium, another botanical extract.

The formula also contains phospholipids, compounds that help your body absorb the other ingredients. These active ingredients are delivered in a base of glycerin, water, ethanol, and vitamin E — the latter three are inactive carriers and stabilizers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Angina — rated "Possibly Effective" (Panax Notoginseng) (Natural Medicines).
  • On file: Intracranial hemorrhage — rated "Possibly Effective" (Panax Notoginseng) (Natural Medicines).
  • On file: Stroke — rated "Possibly Effective" (Panax Notoginseng) (Natural Medicines).
  • On file: Upper respiratory tract infection (URTI) — rated "Possibly Effective" (American Ginseng) (Natural Medicines).

Panax notoginseng is possibly effective for angina (chest pain from restricted blood flow), stroke, and intracranial hemorrhage. The evidence for its use in heart attacks is possibly ineffective, and we don't have enough reliable data to rate it for fatty liver disease (NASH).

American ginseng is possibly effective for upper respiratory tract infections; the data on anemia and breast cancer is insufficient to rate. For Erigeron breviscapus and Epimedium, effectiveness ratings are not established in our data.

The evidence, ingredient by ingredient Panax Notoginseng American Ginseng

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Panax notoginseng is generally well tolerated short-term in healthy adults, though human safety data are limited. Oral side effects are usually mild — dry mouth, flushed skin, insomnia, nausea, nervousness, rash, and vomiting — though a rare case reported serious bleeding in the throat and esophagus after a single dose combined with another anticoagulant.

American ginseng is also generally well tolerated short-term in healthy adults, though quality and long-term safety vary; headache has been reported. The safety data advise against this product during pregnancy and breastfeeding — Panax notoginseng is rated likely unsafe, and American ginseng is rated possibly unsafe in pregnancy with insufficient information for lactation.

Side effects, ingredient by ingredient Panax Notoginseng American Ginseng

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Panax Notoginseng, American Ginseng.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 420 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take warfarin or any blood thinner — American ginseng is a Major concern here. Also double-check if you're on diabetes medications, drugs that suppress your immune system, monoamine oxidase inhibitors (older antidepressants), aspirin, caffeine regularly, or any drug your liver processes quickly (ask your pharmacist if unsure).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This product may appeal to you if you're exploring herbal support for cardiovascular or immune health, but you'll need to be cautious — the ginseng ingredients interact with blood thinners, diabetes drugs, immune suppressants, and older antidepressants. If you take warfarin, any medication for blood sugar, immunosuppressants, or MAOIs, talk with your doctor or pharmacist before starting.

The same goes if you're pregnant, breastfeeding, or planning to be.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Nanoemulsified Noto Bravi, straight from the product label.

Brand Quicksilver Scientific
Barcode (UPC) 752830989184
Net contents 1.7 fl. Oz.; 50 mL
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218640
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Nanoemulsified Noto Bravi by Quicksilver Scientific, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
25
UPC/BARCODE
752830989184
IngredientAmount% DV
Proprietary Blend225 mg--
Phospholipids0 NP--
Ginseng Plus Panax notoginseng root extract0 NP--
Cereboost American Ginseng (Panax quinquefolius) root extract0 NP--
LifeFlower Erigeron breviscapus herb extract0 NP--
Liquid Epimedium extract0 NP--

Other ingredients: Glycerin, Water, Ethanol, Vitamin E

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 2-4 pumps as needed. Hold in mouth 30 seconds before swallowing. May be mixed into water. Repeat to desired dosage or as directed by a healthcare professional. Best taken on an empty stomach at least 10 minutes before meals. Use within 60 days of opening.

General Statements

Quicksilver Delivery Systems: Quicksilver nutraceuticals utilize modern science to unleash the curative power of nature. With the world's most advanced phospholipid delivery systems, Quicksilver Scientific supplements nourish your cells as they deliver their core effective ingredients faster and more effectively.

Quicksilver Delivery Systems Powering natural health

Brand IP Statement(s)

LifeFlower Breviscapine and Ginseng Plus Notoginseng Extract are registered trademarks of Farlong protected by US Patents. Cereboost is the registered trademark of Naturex

Formulation

Immediate effect - superior delivery

FDA Statement of Identity

Dietary Supplement

See for yourself

Nanoemulsified Noto Bravi by Quicksilver Scientific label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Nanoemulsified Noto Bravi by Quicksilver Scientific

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

225 mg per serving

Other (inactive) ingredients: Glycerin, Water, Ethanol, Vitamin E. These complete the product’s ingredient list but are not active constituents.

Interaction report

Nanoemulsified Noto Bravi by Quicksilver Scientific Drug Interactions

Want to check YOUR meds against Nanoemulsified Noto Bravi?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
420Drugs
2 Major 418 Moderate

Each ingredient & the kinds of drugs it affects

For each ingredient in Nanoemulsified Noto Bravi with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cereboost American Ginseng (Panax quinquefolius) root extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D

Ginseng Plus Panax notoginseng root extract4 drug types · 207 drugs

Aspirin

Theoretically, taking Panax notoginseng concomitantly with aspirin may increase the risk of adverse effects from both products.
Animal research shows that taking Panax notoginseng extract with aspirin increases blood levels of salicylic acid by approximately 50% and blood levels of Panax notoginseng by 75% to 196%. This effect may be due to increased absorption of both products.

Likelihood Possible Evidence D
Caffeine

Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction is attributed to the ability of Panax notoginseng to increase the activity of cytochrome P450 1A2 (CYP1A2) enzymes.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction was attributed to the ability of Panax notoginseng to increase the activity of CYP1A2.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking Panax notoginseng concomitantly with warfarin may increase the risk of bleeding.
Animal research shows that taking Panax notoginseng concomitantly with warfarin increases plasma warfarin levels, prothrombin time, and international normalized ratio when compared with control. In vitro research also suggests that Panax notoginseng may downregulate expression of cytochrome P450 3A4 enzymes, which may affect warfarin metabolism.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Nanoemulsified Noto Bravi, from the product label.

Quicksilver Scientific

See all Quicksilver Scientific products
Name
Quicksilver Scientific
Street Address
1376 Miners Dr., #101
City
Lafayette
State
CO
ZipCode
80026
Web Address
quicksilverscientific.com
Pharmacist Counseling Corner

Nanoemulsified Noto Bravi by Quicksilver Scientific: Common Questions

Does Nanoemulsified Noto Bravi by Quicksilver Scientific interact with any medications?
Yes. Based on its ingredients, Nanoemulsified Noto Bravi has a known interaction with 420 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Nanoemulsified Noto Bravi contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
No — both ginseng ingredients in this product interact with warfarin. American ginseng can reduce how well warfarin works and lower your blood clotting protection, and Panax notoginseng may increase bleeding risk. Talk with your doctor or pharmacist before taking this product.
What are the side effects?
The ginseng ingredients are generally well tolerated, but the most common oral side effects are dry mouth, insomnia, nausea, nervousness, rash, and vomiting. A rare case reported serious bleeding in the throat after taking Panax notoginseng with another blood thinner.
Is it safe during pregnancy or breastfeeding?
The safety data advise against it. Panax notoginseng is rated likely unsafe in pregnancy, and American ginseng is rated possibly unsafe. For breastfeeding, there isn't enough reliable information to know either way. Talk with your doctor or pharmacist for personalized advice.
Can I take this with diabetes medication?
American ginseng may lower your blood sugar, so combining it with diabetes drugs could raise your risk of low blood sugar. Check with your doctor or pharmacist before starting.
What is each ingredient supposed to do?
Panax notoginseng is possibly effective for angina, stroke, and intracranial hemorrhage. American ginseng is possibly effective for upper respiratory infections. We don't have established effectiveness data for the Erigeron breviscapus or Epimedium in this formula.
What is the liquid base made of?
The inactive ingredients are glycerin, water, ethanol, and vitamin E — these help stabilize and deliver the active herbal extracts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Nanoemulsified Noto Bravi is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Nanoemulsified Noto Bravi label
Sources

Sources & How We Checked

Nanoemulsified Noto Bravi's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Panax Notoginseng 15 references
  1. Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. New York, NY: CRC Press, LLC 1999:101-102.
  2. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Seattle, WA: Eastland Press, 1996:359-60.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Du XF, Yin XP, Zhang GL, Shi HJ, Shao MH. Interstitial granulomatous drug reaction to a Chinese herb extract. Eur J Dermatol. 2012 May-Jun;22(3):419-20. PubMed
  5. Liu R, Qin M, Hang P, Liu Y, Zhang Z, Liu G. Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo. Phytother Res. 2012 Aug;26(8):1113-8.
  6. Shang Q, Xu H, Liu Z, Chen K, Liu J. Oral Panax notoginseng Preparation for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2013;2013:940125.
  7. Tian Z, Pang H, Du S, Lu Y, Zhang L, Wu H, Guo S, Wang M, Zhang Q. Effect of Panax notoginseng saponins on the pharmacokinetics of aspirin in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:136-143. PubMed
  8. Xu D, Huang P, Yu Z, Xing DH, Ouyang S, Xing G. Efficacy and Safety of Panax notoginseng Saponin Therapy for Acute Intracerebral Hemorrhage, Meta-Analysis, and Mini Review of Potential Mechanisms of Action. Front Neurol. 2015 Jan 7;5:274. PubMed
  9. Yang X, Xiong X, Wang J. Sanqi panax notoginseng injection for angina pectoris. Evid Based Complement Alternat Med. 2014;2014:963208. PubMed
  10. Yin Z, Ma L, Xu J, Xia J, Luo D. Pustular drug eruption due to Panax notoginseng saponins. Drug Des Devel Ther. 2014 Jul 16;8:957-61. PubMed
  11. Song H, Wang P, Liu J, Wang C. Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. Phytother Res. 2017 Jun 20.
  12. Tian Z, Pang H, Zhang Q, et al. Effect of aspirin on the pharmacokinetics and absorption of panax notoginsengsaponins. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 2;1074-75.
  13. Li C, Xu T, Zhou P, et al. Post-marketing safety surveillance and re-evaluation of Xueshuantong injection. BMC Complement Altern Med. 2018;18(1):277. PubMed
  14. Liu L, Shen XJ, Xue LJ, Yao SK, Zhu JY. Submucosal hematoma with a wide range of lesions, severe condition and atypical clinical symptoms: A case report. World J Clin Cases 2021;9(20):5683-5688. PubMed
  15. Qian J, Chen W, Wu J, et al. Effects and Mechanism of Action of Panax notoginseng Saponins on the Pharmacokinetics of Warfarin. Eur J Drug Metab Pharmacokinet 2022;47(3):331-342. PubMed

See these in context on the Panax Notoginseng monograph →

American Ginseng 12 references
  1. Shader RI, Greenblatt DJ. Phenelzine and the dream machine-ramblings and reflections. J Clin Psychopharmacol 1985;5:65. PubMed
  2. Jones BD, Runikis AM. Interaction of ginseng with phenelzine. J Clin Psychopharmacol 1987;7:201-2. PubMed
  3. Janetzky K, Morreale AP. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997;54:692-3. PubMed
  4. Vuksan V, Sievenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13. PubMed
  5. Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. PubMed
  6. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  7. McElhaney JE, Gravenstein S, Cole SK, et al. A Placebo-Controlled Trial of a Proprietary Extract of North American Ginseng (CVT-E002) to Prevent Acute Respiratory Illness in Institutionalized Older Adults. J Am Geriatr Soc 2004;52:13-9. PubMed
  8. Yuan CS, Wei G, Dey L, et al. American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled trial. Ann Intern Med 2004;141:23-7.
  9. Predy GN, Goel V, Lovlin R, et al. Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial. CMAJ 2005;173:1043-8.. PubMed
  10. McElhaney JE, Goel V, Toane B, et al. Efficacy of COLD-fX in the prevention of respiratory symptoms in community-dwelling adults: a randomized, double-blinded, placebo controlled trial. J Altern Complement Med 2006;12:153-7. PubMed
  11. Predy GN, Goel V, Lovlin RE, et al. Immune modulating effects of daily supplementation of COLD-fX (a proprietary extract of North American ginseng) in healthy adults. J Clin Biochem Nutr 2006;39:162-167. DOI
  12. Stavro PM, Woo M, Leiter LA, et al. Long-term intake of North American ginseng has no effect on 24-hour blood pressure and renal function. Hypertension 2006;47(4):791-6. PubMed

See these in context on the American Ginseng monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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