Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

NeuroBiota Ingredients & Drug Interactions

by NS NeuroScience

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

NeuroBiota is a dietary supplement by NS NeuroScience with 2 active ingredients.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of NeuroBiota by NS NeuroScience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (81 mg) without saying how much of each component you get.
  • “ProBlend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “NeuroBlend” is a proprietary blend — the label doesn't break down how much of each component you get.

NeuroBiota contains 9 active ingredients, all of them probiotic bacteria—live microorganisms meant to support your gut health. The main strains are Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04), Lactobacillus paracasei (Lpc-37), Lactobacillus casei (Lc-11), Lactobacillus plantarum (Lp-115), Lactobacillus helveticus (Rosell-52), Lactobacillus rhamnosus (GG), Bifidobacterium longum (Rosell-175), and Lactobacillus brevis (Lbr-135).

Some of these are organized under proprietary blends—ProBlend and NeuroBlend—which means the exact amount of each strain isn't individually listed. The inactive ingredients are a vegetable capsule, microcrystalline cellulose (a filler), and magnesium stearate (a lubricant used in capsule production).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence for NeuroBiota's strains is mixed. Lactobacillus acidophilus shows possibly effective ratings for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis; it's rated possibly ineffective for atopic disease and has insufficient evidence for acute respiratory distress syndrome.

Lactobacillus helveticus and Bifidobacterium longum have insufficient reliable evidence to rate them for any of their listed claims—allergic rhinitis, antibiotic-associated diarrhea, cognitive function, depression, rotaviral diarrhea, exercise-induced respiratory infections, age-related cognitive decline, anxiety, asthma, and athletic performance. The data we hold doesn't establish whether these strains are effective for those purposes.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. The most common side effects from probiotics are gastrointestinal—epigastric discomfort, abdominal pain, bloating, flatulence, diarrhea, vomiting, and burping—but these are uncommon.

Rash and itching have been reported in a clinical trial, though it's unclear whether the L. acidophilus strain itself, other ingredients, or the combination was responsible. A serious but rare concern exists: because these are live organisms, there is some theoretical risk of infection if they translocate (move from where they belong) in vulnerable patients.

Cases of bacteremia, sepsis, and other serious infections have been documented, though most occur in critically ill or immunocompromised individuals. The safety data for Lactobacillus helveticus and Bifidobacterium longum are limited, so caution is advised, especially for anyone who is seriously ill or has a compromised immune system.

For pregnancy, Lactobacillus acidophilus is rated possibly safe and Bifidobacterium longum is rated possibly safe; data for Lactobacillus helveticus during pregnancy and lactation are not on file. Talk with your doctor or pharmacist about whether this product is appropriate for your individual situation.

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lactobacillus Acidophilus, Bifidobacterium Longum, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start NeuroBiota, check whether you're taking any antibiotic drugs (antibacterial medications). All three of the probiotic strains we could evaluate—Lactobacillus acidophilus, Lactobacillus helveticus, and Bifidobacterium longum—interact with antibiotics at a Moderate severity level: the antibiotics may kill enough of the live probiotic organisms to reduce the supplement's effectiveness.

Your doctor or pharmacist can tell you how to space them apart so both work as intended.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

NeuroBiota is a multiprobiotic supplement that may help with irritable bowel syndrome and antibiotic-associated diarrhea (via its Lactobacillus acidophilus content), though evidence for some of its other uses is not established. Anyone taking antibiotics needs to space out the timing—the antibiotics can kill the probiotic organisms, reducing the supplement's effectiveness.

If you're seriously ill, immunocompromised, or pregnant or breastfeeding, talk with your doctor or pharmacist before starting it; the live organisms carry a theoretical risk in these populations. Check your exact medications with the tool on this page, and confirm the timing with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NeuroBiota, straight from the product label.

Brand NS NeuroScience
Barcode (UPC) 659468101738
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244103
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NeuroBiota by NS NeuroScience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
659468101738
IngredientAmount% DV
Lactobacillus acidophilus (La-14)0 NP--
Bifidobacterium lactis (Bl-04)0 NP--
Lactobacillus paracasei Lpc-370 NP--
Lactobacillus casei (Lc-11)0 NP--
Proprietary Blend81 mg--
Lactobacillus plantarum (Lp-115)0 NP--
Lactobacillus helveticus (Rosell-52)0 NP--
Lactobacillus rhamnosus (GG)0 NP--
ProBlend0 NP--
NeuroBlend0 NP--
Bifidobacterium longum (Rosell-175)0 NP--
Lactobacillus brevis (Lbr-135)0 NP--

Other ingredients: Vegetable Capsule, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

If you are pregnant or nursing, consult your healthcare provider before use.

This product has a tamper evident seal under the cap. Do not use if seal is broken or missing.

Keep out of reach of children.

Storage

Store at room temperature, in a cool dry place. No refrigeration required.

FDA Statement of Identity

Dietary Supplement

Formulation

NeuroEnteric

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily or as directed by your healthcare provider. Do not exceed suggested use.

See for yourself

NeuroBiota by NS NeuroScience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in NeuroBiota by NS NeuroScience

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

81 mg per serving
  • › ProBlend
  • › NeuroBlend

Other (inactive) ingredients: Vegetable Capsule, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

NeuroBiota by NS NeuroScience Drug Interactions

Want to check YOUR meds against NeuroBiota?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in NeuroBiota with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for NeuroBiota, from the product label.

NS NeuroScience

See all NS NeuroScience products
Name
NeuroScience
City
Osceola
State
WI
ZipCode
54020
Phone Number
1-888-342-7272
Web Address
www.neuroscienceinc.com
Pharmacist Counseling Corner

NeuroBiota by NS NeuroScience: Common Questions

Does NeuroBiota by NS NeuroScience interact with any medications?
Yes. Based on its ingredients, NeuroBiota has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NeuroBiota contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is this product supposed to do?
NeuroBiota is a probiotic supplement containing nine strains of beneficial bacteria. The strongest evidence supports Lactobacillus acidophilus for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. The other strains are included for various health purposes, but we don't have reliable evidence that they work for the claims made about them.
Can I take this while I'm on antibiotics?
You can, but not at the same time. The antibiotic will kill the live probiotic organisms in this supplement, making it less effective. Ask your doctor or pharmacist how many hours to space them apart—typically a few hours is enough to let each do its job.
Is this safe in pregnancy?
Lactobacillus acidophilus and Bifidobacterium longum are both rated possibly safe in pregnancy, but we don't have safety data on file for Lactobacillus helveticus during pregnancy. Since the product contains multiple strains and your pregnancy is unique to you, talk with your doctor or pharmacist before starting it.
What are the common side effects?
Most people tolerate probiotics well. Gastrointestinal side effects—bloating, gas, abdominal discomfort, or loose stools—are uncommon but can happen, especially when you first start. Rash and itching have been reported rarely in trials, though it's not clear if the probiotic itself was the cause.
Can I take this if I have a weakened immune system?
The safety data is limited for people who are seriously ill or immunocompromised. Because these are live organisms, there is a theoretical risk of infection in vulnerable populations. Check with your doctor or pharmacist before using this product if your immune system is compromised.
Does this help with brain health or mood?
The product is marketed with claims about cognitive function, depression, and anxiety, but we don't have reliable evidence that the probiotic strains in this product are effective for those purposes. The data on file doesn't support those uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NeuroBiota is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NeuroBiota label
Sources

Sources & How We Checked

NeuroBiota's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring