NexaBiotic Pearls Ingredients & Drug Interactions
by DrFormulas
What is this page for?
First and foremost: checking NexaBiotic Pearls against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
NexaBiotic Pearls is a dietary supplement by DrFormulas with 9 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum, Bifidobacterium breve. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against NexaBiotic Pearls by DrFormulas
Ask about any prescription or over-the-counter medication and we check it for interactions with NexaBiotic Pearls by DrFormulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of NexaBiotic Pearls by DrFormulas
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
NexaBiotic Pearls contains 9 active ingredients: six different strains of beneficial bacteria (probiotics) meant to support your gut health, plus a branched-chain amino acid matrix that serves as a transport and support system. The probiotic strains are Lactobacillus plantarum, Bifidobacterium animalis lactis, Lactobacillus fermentum, Bifidobacterium longum, Bifidobacterium infantis, Bifidobacterium breve, Lactobacillus casei, Lactobacillus reuteri, and Enterococcus faecium.
The product also includes inactive ingredients—microcrystalline cellulose, hydroxypropyl methylcellulose, pectin, stearic acid, sodium carbonate, orange flavor, stevia leaf extract, guar gum, and turmeric—which are fillers, binders, and flavoring agents.
Does it work?
Not established
The evidence backing these probiotics is thin. For Bifidobacterium longum, we have insufficient reliable evidence to rate whether it helps with age-related thinking changes, hay fever, antibiotic-related diarrhea, anxiety, asthma, or athletic performance.
Bifidobacterium breve shows possibly ineffective ratings for age-related cognitive decline and sepsis, and insufficient evidence for hay fever, antibiotic-related diarrhea, and atopic disease. For the other bacterial strains in this product, effectiveness data isn't on file with us.
How safe is it?
Well-documented data
Both Bifidobacterium longum and Bifidobacterium breve are generally well tolerated in healthy people, but they come with cautions. If you're seriously ill, have a weakened immune system, or are in critical condition, these probiotics aren't appropriate—there are rare but documented cases of bloodstream infection (bacteremia) and sepsis in critically ill infants and adults who took them.
When taken by mouth, rare gastrointestinal side effects have been reported: abdominal discomfort, pain, bloating, flatulence, constipation, and in one case a dry cough. For pregnancy and breastfeeding, Bifidobacterium longum is rated possibly safe, but Bifidobacterium breve has limited safety data; check with your doctor or pharmacist for personalized guidance before use in either situation.
Meds to double-check
Moderate interaction found
Before you take NexaBiotic Pearls, check with your doctor or pharmacist if you're on antibiotic drugs. Because the probiotics in this product are living organisms, antibiotics can kill them and make them less effective—you may need to time them separately.
We couldn't check several of the bacterial strains for other medications, so it's worth running all your prescriptions through the tool on this page just to be thorough.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
NexaBiotic Pearls is a multi-strain probiotic meant for gut health, but the evidence supporting its benefits is sparse. If you take antibiotics, you'll need to separate them from this product by timing.
If you're critically ill, immunocompromised, pregnant, or breastfeeding, talk with your doctor or pharmacist before starting it—the safety profile in those situations isn't clear enough to go it alone.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about NexaBiotic Pearls, straight from the product label.
| Brand | DrFormulas |
|---|---|
| Barcode (UPC) | X000ZSLQ8N |
| Net contents | 60 Probiotic Pearl(s) |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2019 |
| DSLD ID | 203837 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegetarian, Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for NexaBiotic Pearls by DrFormulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus plantarum | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Lactobacillus fermentum | 0 NP | -- |
| Bifidobacterium longum | 0 NP | -- |
| Bifidobacterium infantis | 0 NP | -- |
| Bifidobacterium breve | 0 NP | -- |
| Lactobacillus casei | 0 NP | -- |
| Lactobacillus reuteri | 0 NP | -- |
| Enterococcus faecium | 0 NP | -- |
| 8:1:1 Branched Chain Amino Acid Matrix & Transport System | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Pectin, Stearic Acid, Sodium Carbonate, Orange flavor, Stevia leaf extract, Guar Gum, Turmeric
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Allergen warning: Contains milk proteins but is suitable for those on a lactose-free/lactose-restricted diet.
Allergen warning: Contains milk proteins but is suitable for those on a lactose-free/lactose-restricted diet.
For kids and adults
Precautions
Allergen warning: Contains milk proteins but is suitable for those on a lactose-free/lactose-restricted diet.
Caution: Do not exceed recommended dose. Consult a physician before using this or any dietary supplement.
Warning: Choking hazard: Not for children 3 years of younger. Keep out of reach of children.
Do not use if safety seal is damaged or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Stomach acid resistant probiotic pearls Easily swallowed with adult supervision 9 probiotics strains, 6.0 billion CFUs
Visit DrFormulas.com/coupon
Customer satisfaction 100% guaranteed
Reorder at: www.drformulas.com 1-888-406-6499 [email protected]
FDA Statement of Identity
Chewable Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take up to two (2) probiotic pearls a day. For best results take product on an empty stomach.
Formulation
This product is vegetarian, non-GMO, and free of: yeast, lactose, soy, iron, gluten, wheat, nuts, preservatives, sugar, artificial color, and artificial flavors.
This product is vegetarian, non-GMO, and free of: yeast, lactose, soy, iron, gluten, wheat, nuts, preservatives, sugar, artificial color, and artificial flavors.
Storage
Store in a cool dry place.
Seals/Symbols
Made in the USA With US & Imported Ingredients Good Manufacturing Practice GMP Quality Assured
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
NexaBiotic Pearls by DrFormulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in NexaBiotic Pearls by DrFormulas
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Delayed Release Pearl(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
8:1:1 Branched Chain Amino Acid Matrix & Transport System
- › Lactobacillus plantarum
- › Bifidobacterium animalis lactis
- › Lactobacillus fermentum
- › Bifidobacterium longum
- › Bifidobacterium infantis
- › Bifidobacterium breve
- › Lactobacillus casei
- › Lactobacillus reuteri
- › Enterococcus faecium
Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Pectin, Stearic Acid, Sodium Carbonate, Orange flavor, Stevia leaf extract, Guar Gum, Turmeric. These complete the product’s ingredient list but are not active constituents.
NexaBiotic Pearls by DrFormulas Drug Interactions
HelloPharmacist Interaction Report
NexaBiotic Pearls by DrFormulas contains several probiotic bacteria, and two of them—Bifidobacterium longum and Bifidobacterium breve—have documented interactions with medications.
The most serious concern is a Moderate interaction with antibiotic drugs (antibiotics): because these probiotics are living organisms, taking antibiotics at the same time might kill them off and reduce how well the probiotic works. You'll want to space out your antibiotics and this product.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we couldn't check four other bacterial ingredients in this formula—Lactobacillus plantarum, Lactobacillus fermentum, Bifidobacterium infantis, Lactobacillus casei, Lactobacillus reuteri, and Enterococcus faecium—because we hold no interaction data for them. That doesn't mean they're risk-free with medications; it just means we haven't reviewed them yet.
Altogether, these interactions span 182 individual medications. Before you start NexaBiotic Pearls, especially if you take antibiotics or any other prescription drugs, run your exact medications through the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against NexaBiotic Pearls?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in NexaBiotic Pearls interact with 182 drugs. Click any drug to see the details.
2 of the 9 ingredients in NexaBiotic Pearls interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum Bifidobacterium breve
CefotetanCefotan
How Cefotetan interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefotetan interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefotetan interactionCefoxitinMefoxin
How Cefoxitin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefoxitin interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefoxitin interactionCefpodoxime ProxetilVantin
How Cefpodoxime Proxetil interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefpodoxime Proxetil interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefpodoxime Proxetil interactionCefprozilCefzil
How Cefprozil interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefprozil interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefprozil interactionCeftazidimeCeftazidime, Ceptaz, Fortaz, Tazicef, Tazidime
How Ceftazidime interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftazidime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftazidime interactionCeftibutenCedax
How Ceftibuten interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftibuten interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftibuten interactionCeftizoximeCefizox
How Ceftizoxime interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftizoxime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftizoxime interactionCeftolozane Sulfate, Tazobactam SodiumZerbaxa
How Ceftolozane Sulfate, Tazobactam Sodium interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftolozane Sulfate, Tazobactam Sodium interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftolozane Sulfate, Tazobactam Sodium interactionCeftriaxoneRocephin
How Ceftriaxone interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ceftriaxone interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ceftriaxone interactionCefuroximeCeftin, Kefurox, Zinacef
How Cefuroxime interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cefuroxime interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefuroxime interactionCephalexinCephalex, Keflex, Keftab, Lexin
How Cephalexin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephalexin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephalexin interactionCephapirinCefadyl
How Cephapirin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephapirin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephapirin interactionCephradineAnspor, Velosef
How Cephradine interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cephradine interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cephradine interactionChloramphenicolChloromycetin, Chloromycetin Injection, Chloromycetin Ophthalmic
How Chloramphenicol interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Chloramphenicol interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Chloramphenicol interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Chlortetracycline interactionBifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Chlortetracycline interactionCinoxacinCinobac
How Cinoxacin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cinoxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cinoxacin interactionCiprofloxacinCiloxan, Cipro, Cipro IV, Cipro XR, Ciprobay, Otiprio
How Ciprofloxacin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Ciprofloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ciprofloxacin interactionClarithromycinBiaxin, Biaxin XL
How Clarithromycin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clarithromycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clarithromycin interactionClinafloxacinClinafloxacin
How Clinafloxacin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clinafloxacin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clinafloxacin interactionClindamycinCleocin, Cleocin T Gel, ClindaMax, Clindesse, Dalacin C
How Clindamycin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clindamycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clindamycin interactionClofazimineLamprene
How Clofazimine interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Clofazimine interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Clofazimine interactionCloxacillin SodiumCloxapen, Cloxi, Tegopen
How Cloxacillin Sodium interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cloxacillin Sodium interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cloxacillin Sodium interactionColistimethateColy-Mycin M
How Colistimethate interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Colistimethate interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Colistimethate interactionCyclacillinCyclapen-W, Cylcapen
How Cyclacillin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cyclacillin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cyclacillin interactionCycloserineSeromycin
How Cycloserine interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Cycloserine interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cycloserine interactionDalbavancin HydrochlorideDalvance
How Dalbavancin Hydrochloride interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dalbavancin Hydrochloride interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dalbavancin Hydrochloride interactionDapsoneAczone, Avlosulfon, Dapsone
How Dapsone interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dapsone interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dapsone interactionDaptomycinCubicin, Dapzura RT
How Daptomycin interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Daptomycin interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Daptomycin interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Demeclocycline interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Demeclocycline interactionDicloxacillin InjectionDynapen Injection
How Dicloxacillin Injection interacts with NexaBiotic Pearls — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium BreveAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Breve + Dicloxacillin Injection interactionBifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Dicloxacillin Injection interactionEach ingredient & the kinds of drugs it affects
For each ingredient in NexaBiotic Pearls with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Bifidobacterium breve
Antibiotic Drugs
Theoretically, taking Bifidobacterium breve with antibiotic drugs might decrease the effectiveness of B. breve.
Since B. breve preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. breve preparations by at least 2 hours.
Brand information
Manufacturer and brand details for NexaBiotic Pearls, from the product label.
DrFormulas
See all DrFormulas products- Name
- DrFormulas
- Street Address
- 5622 Buckingham Dr
- City
- Huntington Beach
- State
- CA
- ZipCode
- 92649
- Phone Number
- 1-888-406-6499
- Web Address
- www.drformulas.com
NexaBiotic Pearls by DrFormulas: Common Questions
Does NexaBiotic Pearls by DrFormulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on antibiotics?
Is it safe to take NexaBiotic Pearls while breastfeeding?
What's the branched-chain amino acid in here for?
Does this actually help with digestive health?
Who shouldn't take this product?
What side effects might I notice?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if NexaBiotic Pearls is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind NexaBiotic Pearls’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographBifidobacterium Breve
Interacts with 182 drugsBifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...
Read the full Bifidobacterium Breve monograph →Sources & How We Checked
NexaBiotic Pearls's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Bifidobacterium Breve 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Ohishi A, Takahashi S, Ito Y, et al. Bifidobacterium septicemia associated with postoperative probiotic therapy in a neonate with omphalocele. J Pediatr. 2010;156(4):679-81. PubMed
- Sakurai Y, Watanabe T, Miura Y, et al. Clinical and bacteriologic characteristics of six cases of Bifidobacterium breve bacteremia due to probiotic administration in the neonatal intensive care unit. Pediatr Infect Dis J 2022;41(1):62-65. PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Wakabayashi Y, Nakayama S, Yamamoto A, et al. First case of necrotizing fasciitis and bacteremia caused by Bifidobacteriumbreve. Anaerobe 2022;76:102613.
- Takeda Y, Ota K, Kondo A, et al. A case of necrotizing fasciitis caused by Bifidobacterium breve. IDCases 2022;31:e01667. PubMed
- Suwantarat N, Romagnoli M, Wakefield T, Carroll KC. Ventriculoperitoneal shunt infection caused by Bifidobacterium breve. Anaerobe 2014;28:1-3. PubMed
See these in context on the Bifidobacterium Breve monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC