Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

NZ-Prostate Max Ingredients & Drug Interactions

by Everyday Health

NZ-Prostate Max label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NZ-Prostate Max against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

NZ-Prostate Max is a dietary supplement by Everyday Health with 6 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 401 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto Berry Extract, Stinging Nettle Root Extract, Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against NZ-Prostate Max by Everyday Health

Ask about any prescription or over-the-counter medication and we check it for interactions with NZ-Prostate Max by Everyday Health — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of NZ-Prostate Max by Everyday Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

NZ-Prostate Max contains six active ingredients, each chosen for urinary or prostate health. Pumpkin seed extract is possibly effective for benign prostatic hyperplasia (BPH).

Zinc is a mineral needed for immunity and wound healing and is effective for zinc deficiency. Saw palmetto berry extract is possibly ineffective for BPH based on current evidence.

Stinging nettle root extract is possibly effective for diabetes and may support urinary function. Pygeum bark extract is likely effective for benign prostatic hyperplasia.

Lycopene is a carotenoid (plant pigment) possibly effective for prostate cancer. The product also contains inactive ingredients—gelatin and rice flour—which act as a capsule and filler.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support optimal prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Erectile dysfunction (ED), Prostate enlargement, Lower urinary tract symptoms, Male urinary health.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).

The evidence for this product is mixed. Pygeum bark is likely effective for BPH, and both pumpkin and stinging nettle root are possibly effective for BPH — though saw palmetto appears possibly ineffective for that condition based on current research.

Lycopene is possibly effective for prostate cancer specifically. Zinc is effective for zinc deficiency but has only possibly effective evidence for diabetes.

For most of the other uses these ingredients are studied for — hair loss, hay fever, anemia, asthma, and others — we don't have reliable evidence to rate them.

The evidence, ingredient by ingredient Pumpkin Zinc Saw Palmetto Stinging Nettle Pygeum Lycopene

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin and saw palmetto are generally well tolerated, though pumpkin may cause abdominal discomfort, diarrhea, nausea, or vomiting, and rare cases of hair loss or anaphylaxis have been reported. Zinc is well tolerated below 40 mg daily but can cause metallic taste, nausea, diarrhea, and abdominal cramps at higher doses; long-term high-dose use may deplete copper.

Saw palmetto may cause abdominal pain, decreased libido, diarrhea, dizziness, headache, and rarely serious cardiac effects. Stinging nettle is generally well tolerated but has caused liver injury in rare case reports.

Pygeum is generally well tolerated short-term. Lycopene may cause diarrhea, bloating, nausea, or vomiting.

For pregnancy: pumpkin food is fine but concentrated supplements lack safety data. Saw palmetto is likely unsafe in pregnancy.

Stinging nettle is likely unsafe in pregnancy. Pygeum and lycopene have no established safe use or insufficient data in pregnancy — talk with your doctor.

For breastfeeding: safety data are limited or absent for pumpkin concentrates, saw palmetto, stinging nettle, and lycopene supplements — discuss with your pharmacist or doctor before use.

Side effects, ingredient by ingredient Pumpkin Zinc Saw Palmetto Stinging Nettle Pygeum Lycopene

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Lycopene, Stinging Nettle, Pumpkin, Saw Palmetto, Zinc.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 401 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on lithium (pumpkin and stinging nettle may increase levels), blood thinners or antiplatelet drugs like warfarin or aspirin (saw palmetto and lycopene may increase bleeding risk; stinging nettle interferes with warfarin), diabetes medications (stinging nettle may have additive effects), diuretics (pumpkin and stinging nettle may have additive effects), estrogens or contraceptives (saw palmetto may reduce effectiveness), antibiotics including quinolones, tetracyclines, or cephalexin (zinc reduces absorption), HIV medications including ritonavir, integrase inhibitors, or Biktarvy (zinc may lower levels), or cancer drugs like cisplatin (zinc may interfere). These are moderate-severity concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

NZ-Prostate Max targets benign prostatic hyperplasia and prostate health with a mix of herbal extracts and micronutrients, of which pygeum is likely effective and pumpkin and stinging nettle are possibly effective for BPH. If you take lithium, blood thinners, diabetes medications, diuretics, estrogens, contraceptives, antibiotics, or HIV drugs, check your exact medications with your doctor or pharmacist before starting — this product has moderate interactions across a broad range of medications.

If you're pregnant or breastfeeding, talk with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NZ-Prostate Max, straight from the product label.

Brand Everyday Health
Barcode (UPC) 9421905900065
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306117
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NZ-Prostate Max by Everyday Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
9421905900065
IngredientAmount% DV
Pumpkin50 mg--
Zinc15 mg100%
Saw Palmetto Berry Extract320 mg--
Stinging Nettle Root Extract240 mg--
Pygeum Bark Extract100 mg--
Lycopene5 mg--

Other ingredients: Gelatin, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Contains no sugar, salt, artificial colours or flavors.

New Zealand Premium Quality Essential formula for prostate Made in New Zealand from premium imported ingredients Support prostate health

Manufactured under GMP Satisfaction guaranteed

Formula

NZ-Prostate Max is a high strength formula combining saw palmetto, nettle, pumpkin seed extracts, and other valuable herbs to support optimal prostate health.

Saw palmetto berry extract Stinging nettle extract Pygeum extract Pumpkin seed Zinc, lycopene

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Only one time per day!

Directions Take two (02) capsules a day, on an empty stomach, or as directed by your health care professional.

Precautions

Caution Keep out of reach of children.

Not recommended for use by pregnant and lactation women.

Contact healthcare professionals immediately if you have any side effects. Do not use if outer seal or seal under cap is broken or missing.

Storage

Keep tightly closed in a cool dry place.

General Statements

Satisfaction 100% guaranteed

www.prostatemax.nz

Seals/Symbols

GMP Certified Good Manufacturing Practice

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NZ-Prostate Max by Everyday Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NZ-Prostate Max label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NZ-Prostate Max by Everyday Health

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pumpkin

Interacts with
1 drug
50 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin monograph & interactions

Zinc

Interacts with
67 drugs
15 mg per serving Form: Zinc Acetate

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc monograph & interactions

Saw Palmetto Berry Extract

Interacts with
174 drugs
320 mg per serving Form: Fatty Acids

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto Berry Extract monograph & interactions

Stinging Nettle Root Extract

Interacts with
164 drugs
240 mg per serving Form: Beta-Sitosterol, Total Amino Acids

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...

Stinging Nettle Root Extract monograph & interactions

Pygeum Bark Extract

No known
interactions
100 mg per serving Form: Pygeum africanum Bark Extract

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum Bark Extract monograph & interactions

Lycopene

Interacts with
122 drugs
5 mg per serving Form: natural Tomato extract

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

NZ-Prostate Max by Everyday Health Drug Interactions

Want to check YOUR meds against NZ-Prostate Max?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
401Drugs
398 Moderate 3 Minor

Ingredients driving the most interactions

Saw Palmetto Berry Extract 174
Stinging Nettle Root Extract 164
Lycopene 122
Zinc 67
Pumpkin 1

Individual Drug Interactions

The ingredients in NZ-Prostate Max interact with 401 drugs. Click any drug to see the details.

5 of the 6 ingredients in NZ-Prostate Max interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto Berry Extract Stinging Nettle Root Extract Lycopene Zinc Pumpkin

Each ingredient & the kinds of drugs it affects

For each ingredient in NZ-Prostate Max with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saw Palmetto Berry Extract3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Berry Extract full monograph & interactions

Stinging Nettle Root Extract4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle Root Extract full monograph & interactions

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions

Zinc10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc full monograph & interactions

Pumpkin1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for NZ-Prostate Max, from the product label.

Everyday Health

See all Everyday Health products
Name
Everyday Health Ltd
Street Address
3, 1 Kingsford Smith Drive
City
Rangiora
Web Address
www.everydayhealth.nz
Pharmacist Counseling Corner

NZ-Prostate Max by Everyday Health: Common Questions

Does NZ-Prostate Max by Everyday Health interact with any medications?
Yes. Based on its ingredients, NZ-Prostate Max has a known interaction with 401 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NZ-Prostate Max contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product affect my blood thinner?
Possibly. Saw palmetto and lycopene theoretically increase bleeding risk, and stinging nettle contains vitamin K which may interfere with warfarin. Talk with your doctor or pharmacist before taking it alongside any blood thinner or antiplatelet drug — they can tell you if it's safe for you or if timing adjustments help.
What's actually in this for prostate health?
Pygeum bark is likely effective for BPH. Pumpkin seed extract and stinging nettle root are possibly effective for it. Saw palmetto is possibly ineffective based on current evidence, though it's a common prostate ingredient. Lycopene is possibly effective specifically for prostate cancer risk. Together they cover a few angles, though pygeum is the strongest evidence-backed one here.
Can I take this if I'm on an antibiotic?
The zinc in this product can reduce absorption of many antibiotics — especially quinolones, tetracyclines, and cephalexin — if taken at the same time. You'd need to space them at least 2–6 hours apart. Check with your pharmacist about which antibiotic you're on and the best timing.
What are the most common side effects?
Most adverse effects are mild: pumpkin and zinc may cause abdominal discomfort, diarrhea, nausea, or vomiting. Saw palmetto may cause headache, dizziness, or decreased libido. Lycopene may cause bloating or diarrhea. Serious side effects are rare but have been reported.
Is this safe in pregnancy?
There isn't enough safety data to know either way for most of these ingredients in pregnancy. Saw palmetto and stinging nettle are considered likely unsafe. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy — they can weigh the risks and benefits for your situation.
Can I take this with my diabetes medication?
Stinging nettle may lower blood sugar and theoretically have additive effects with diabetes drugs. This doesn't automatically mean you can't take it, but your doctor or pharmacist should know you're adding it so they can monitor your blood sugar or adjust your medication dose if needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NZ-Prostate Max is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NZ-Prostate Max label
Go deeper

The Full Monographs Behind NZ-Prostate Max’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Pygeum

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...

Read the full Pygeum monograph → Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

NZ-Prostate Max's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 151 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Zinc 88 references
  1. Barceloux DG. Zinc. J Toxicol Clin Toxicol 1999;37:279-92.
  2. Eby GA, Davis DR, Halcomb WW. Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study. Antimicrob Agents Chemother 1984;25:20-4. DOI
  3. Smith DS, Helzner EC, Nuttall CE Jr, et al. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Antimicrob Agents Chemother 1989;33:646-8. PubMed
  4. Blondeau JM. Expanded activity and utility of the new fluoroquinolones: a review. Clin Ther 1999;21:3-40. PubMed
  5. Reyes AJ, Olhaberry JV, Leary WP, et al. Urinary zinc excretion, diuretics, zinc deficiency and some side-effects of diuretics. S Afr Med J 1983;64:936-41.
  6. Kugelmas M. Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. J Am Coll Nutr 2000;19:13-5. PubMed
  7. Hebel SK, ed. Drug Facts and Comparisons. 52nd ed. St. Louis: Facts and Comparisons, 1998.
  8. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  9. Brewer GJ, Yuzbasiyan-Gurkan V, Johnson V, et al. Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents. J Am Coll Nutr 1993;12:26-30. PubMed
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Saw Palmetto 22 references
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Stinging Nettle 23 references
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Pygeum 3 references
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Lycopene 10 references
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  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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