Oat Fiber Powder Unflavored Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Oat Fiber Powder Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Oat Fiber Powder Unflavored is a dietary supplement by Solaray with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,130 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Oat. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Oat Fiber Powder Unflavored by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Oat Fiber Powder Unflavored by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Oat Fiber Powder Unflavored by Solaray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Solaray Oat Fiber Powder has one active ingredient: beta-glucans. These are soluble fibers naturally found in oats and other grains.
The product contains no inactive fillers or other ingredients beyond the oat fiber itself.
Does it work?
Strong evidence
Beta-glucans are likely effective for improving cholesterol levels (dyslipidemia) and supporting heart health in coronary heart disease. That evidence comes from clinical research showing real benefits in people with these conditions.
How safe is it?
Well-documented data
Beta-glucans from food sources like oatmeal are generally well tolerated by most people. However, concentrated supplements don't have as much safety data behind them, so caution is warranted.
For breastfeeding, there's little research on supplement doses, so talk with your doctor or pharmacist before taking this while nursing. When beta-glucans are applied to skin, contact dermatitis and other skin reactions can occur; one trial reported mild, self-resolving reactions in about 12% of people using a topical beta-glucans cream.
Oral beta-glucans are well tolerated, though one patient in a high-dose pediatric trial experienced a temporary rise in liver enzymes.
Meds to double-check
Moderate interaction found
Check your blood pressure medications and any immunosuppressant drugs with the tool below before starting. Both types carry Moderate risk of interaction with beta-glucans.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a single-ingredient fiber supplement backed by evidence for cholesterol and heart health. If you take blood pressure medication or an immunosuppressant (like after a transplant), run your medications through the checker on this page first.
Otherwise, talk with your pharmacist to make sure it fits your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Oat Fiber Powder Unflavored, straight from the product label.
| Brand | Solaray |
|---|---|
| Barcode (UPC) | 076280544084 |
| Net contents | 11.6 Ounce(s); 328 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 338504 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Oat Fiber Powder Unflavored by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 30 Calorie(s) | -- |
| Total Carbohydrates | 7 Gram(s) | 2% |
| Total Fat | 1 Gram(s) | 1% |
| Dietary Fiber | 5 Gram(s) | 19% |
| Protein | 2 Gram(s) | -- |
| Beta-Glucan | 3 Gram(s) | -- |
| Oat | 11 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Solaray Est. 1973 A Brighter Way 1973
Formula
Standardized to Beta Glucans
Discussion: Solaray Oat Fiber has been standardized to beta glucans, soluble fibers shown to support heart health and cardiovascular health.
Formulation
Supports: Heart health Cardiovascular health
Vegan
Made without soy
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Lab Verified Vegan
General Statements
Since 1973, we've scoured the globe for the highest-quality ingredients, connecting you with the most efficacious supplements that help you live brighter and embrace the moments that matter most.
Comments or Questions: 800-538-5888 www.solaray.com
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product. Directions: Use only as directed.
Keep out of reach of children.
California Residents Only Warning: Reproductive Harm - www.P65Warnings.ca.gov.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Mix 1 scoop into 8 ounces of water, beverage or smoothie daily. Tastes great hot or cold. May also be used in recipes or sprinkled on foods.
Storage
Store in a cool, dry place.
Packaged by weight, not volume. Some settling of contents may occur.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Oat Fiber Powder Unflavored by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Oat Fiber Powder Unflavored by Solaray
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size11 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProtein
Oat
Interacts with86 drugs
Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a f...
Oat monograph & interactionsOat Fiber Powder Unflavored by Solaray Drug Interactions
HelloPharmacist Interaction Report
Solaray Oat Fiber Powder Unflavored contains beta-glucans, which can interact with blood pressure medications and drugs that suppress the immune system.
The main concern is with antihypertensive drugs (medications that lower blood pressure) — beta-glucans may further reduce blood pressure, raising the risk of low blood pressure (hypotension). This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Beta-glucans may also interfere with immunosuppressants (drugs that dampen the immune system), since beta-glucans appear to stimulate immune function. This is also Moderate severity.
Altogether, these interactions span 287 individual medications.
We could not check oat itself for interactions — the product lists it as a blend, with its components shown individually. Use the medication checker on this page to look up your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Oat Fiber Powder Unflavored?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Oat Fiber Powder Unflavored interact with 2,130 drugs. Click any drug to see the details.
2 of the 3 ingredients in Oat Fiber Powder Unflavored interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Oat
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Acarbose interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Acebutolol interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Acetazolamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Acetohexamide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Acetohexamide interactionAdalimumabHumira
How Adalimumab interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-bwwd interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Oat Fiber Powder Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta-glucan + Alemtuzumab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Aliskiren interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Alogliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionOatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
OatAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full Oat + Alogliptin, Pioglitazone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Ambrisentan interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amiloride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amiloride, Hydrochlorothiazide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine Benzoate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine Besilate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine Besylate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine Besylate, Benazepril interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Amlodipine, Celecoxib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Oat Fiber Powder Unflavored — through 2 ingredients. Tap an ingredient for the detail:
Beta-glucanAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta-glucan + Ammonium Chloride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ammonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Oat Fiber Powder Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Oat
Antidiabetes Drugs
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Insulin
Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Brand information
Manufacturer and brand details for Oat Fiber Powder Unflavored, from the product label.
Solaray
See all Solaray products- Name
- Solaray
- City
- Salt Lake City
- State
- UT
- ZipCode
- 84101
- Phone Number
- 800-538-5888
- Web Address
- www.solaray.com
Oat Fiber Powder Unflavored by Solaray: Common Questions
Does Oat Fiber Powder Unflavored by Solaray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this supplement actually help with cholesterol and heart health?
What are the common side effects?
Can I take this while breastfeeding?
Is this safe for children?
Why is it just one ingredient?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Oat Fiber Powder Unflavored is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Oat Fiber Powder Unflavored’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographOats
Interacts with 86 drugsOats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...
Read the full Oats monograph → Herb & supplement monographBeta-glucans
Interacts with 293 drugsBeta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...
Read the full Beta-glucans monograph →Sources & How We Checked
Oat Fiber Powder Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 42 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Beta-glucans 11 references
- Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
- Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
- Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
- Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
- Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
- Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
- McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
- Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
- Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
- Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
- Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed
Oats 13 references
- Cooper SG, Tracey EJ. Small-bowel obstruction caused by oat-bran bezoar. N Engl J Med 1989;320:1148-9. DOI
- Pick ME, Hawrysh ZJ, Gee MI, et al. Oat bran concentrate bread products improve long-term control of diabetes: a pilot study. J Am Diet Assoc 1996;96:1254-61. PubMed
- Braaten JT, Scott FW, Wood PJ, et al. High beta-glucan oat bran and oat gum reduce postprandial blood glucose and insulin in subjects with and without type 2 diabetes. Diabet Med 1994;11:312-8.
- Rosario PG, Gerst PH, Prakash K, Albu E. Dentureless distention: oat bran bezoars cause obstruction. J Am Geriatr Soc 1990;38:608. PubMed
- Food and Drug Administration. Food labeling: health claims: oats and coronary heart disease. Fed Regist 1996;61:296-313.
- Foulke J. FDA Allows Whole Oat Foods To Make Health Claim on Reducing the Risk of Heart Disease. FDA Talk Paper. 1997. Available at: http://www.fda.gov/bbs/topics/ANSWERS/ANS00782.html.
- Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000;342:1392-8. PubMed
- Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
- De Paz Arranz S, Perez Montero A, Remon LZ, Molero MI. Allergic contact urticaria to oatmeal. Allergy 2002;57:1215. . PubMed
- Delgado G, Kleber ME, Krämer BK, et al. Dietary intervention with oatmeal in patients with uncontrolled type 2 diabetes mellitus - A crossover study. Exp Clin Endocrinol Diabetes. 2019;127(9):623-629. PubMed
- Sobhan M, Hojati M, Vafaie SY, Ahmadimoghaddam D, Mohammadi Y, Mehrpooya M. The efficacy of colloidal oatmeal cream 1% as add-on therapy in the management of chronic irritant hand eczema: A double-blind study. Clin Cosmet Investig Dermatol. 2020;13:241-25
- Hou Q, Li Y, Li L, Cheng G, Sun X, Li S, Tian H. The metabolic effects of oats intake in patients with type 2 diabetes: A systematic review and meta-analysis. Nutrients. 2015;7(12):10369-87. PubMed
- González-Afonso M, Cañas JA, Sastre B, et al. A Case of Anaphylaxis After Ingestion of Oats: Research Into New Allergens. J Investig Allergol Clin Immunol 2022;32(6):506-508. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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