Omega Cardio Performance Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Omega Cardio Performance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Omega Cardio Performance is a dietary supplement by Rainbow Light with 9 active ingredients. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 985 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, Omega-3 Fatty Acids, purified deep sea Fish Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Omega Cardio Performance by Rainbow Light
Ask about any prescription or over-the-counter medication and we check it for interactions with Omega Cardio Performance by Rainbow Light — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Omega Cardio Performance by Rainbow Light
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients list an amount, but at least one is hidden in a blend or missing.
Why this rating?
- The label discloses an exact amount for 9 of its 14 active ingredients.
- “Omega-3 Fatty Acids” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
- “Omega-6 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (23 mg) without saying how much of each component you get.
- “Omega-9 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (76 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 5 of the 5 matched ingredients can interact with medications — Lemon, Vitamin D, Coenzyme Q10, Fish Oil, Oleic Acid.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
- For scale: 986 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 5 of 5.
- General safety write-ups exist for 5 of 5.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryPartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 5 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Omega Cardio Performance, straight from the product label.
| Brand | Rainbow Light |
|---|---|
| Barcode (UPC) | 021888850211 |
| Net contents | 60 Softgel(s) |
| Market status | Off market |
| Date entered into DSLD | Mar 25, 2015 |
| DSLD ID | 43132 |
| Product type | Botanical With Nutrients |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Approved Health, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Omega Cardio Performance by Rainbow Light, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 30 {Calories} | -- |
| Calories from Fat | 21 {Calories} | -- |
| Omega-3 Fatty Acids | 0 NP | -- |
| Eicosapentaenoic Acid | 286 mg | -- |
| Docosahexaenoic Acid | 248 mg | -- |
| Gamma-Linolenic Acid | 0 NP | -- |
| Omega-6 Fatty Acids | 23 mg | -- |
| Omega-9 Fatty Acids | 76 mg | -- |
| Total Fat | 1 Gram(s) | 1% |
| Total Omega-3 Fatty Acids | 642 mg | -- |
| Other Omega-3 Fatty Acids | 108 mg | -- |
| Linoleic Acid | 0 NP | -- |
| Arachidonic Acid | 0 NP | -- |
| Oleic Acid | 0 NP | -- |
| Vitamin D | 1000 IU | 250% |
| Coenzyme Q10 | 100 mg | -- |
| Eicosanoic Acid | 0 NP | -- |
| Lemon essential Oil | 10 mg | -- |
| Plant Sterol Esters | 800 mg | -- |
| purified deep sea Fish Oil | 920 mg | -- |
Other ingredients: yellow Beeswax, Silica, Softgel Shell
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Manufactured in the Colombia
A full essential fatty acid profile necessary for healthy cell membrane function and normal inflammation response. Plant Sterol Esters promote normal cholesterol levels. Foods containing at least 0.5 g per serving of phytosterols eaten with meals or snacks for a daily total intake of 2 g as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease.
Helps keep blood flowing to feed organs and tissues while protecting against oxidation.
Pure and Sustainable. Moleculary distilled fish oil from only small wild catch fish species from deep, cold Peruvian waters are more sustainable and purer than larger species.
Cholesterol Lowering Plant Sterols
To open, press along perforation. Please remove label before recycling.
Formula
Contains soy.
Comprehensive Omega Formula for Heart Health Support with naturally occurring omegas, including EPA and DHA at researched levels for cardiovascular health supported by leading health organizations (AHA, ISSFAL and GOED).
A serving of Omega Cardio Performance(TM) supplies .6 g of phytosterols.
Optimal dose of CoQ10 benefits heart muscle function and facilitates cellular energy.
Researched EPA & DHA Levels
100 mg CoQ10 & 1,000 IU Vitamin D3
Precautions
Contains soy.
KEEP OUT OF REACH OF CHILDREN.
Consult your health care professional prior to use if you are pregnant, lactating, taking medication or have a medical condition.
Brand IP Statement(s)
(C)2012
Rainbow Light(R) is a GOED member (Global Organization for EPA and DHA Omega-3 Fatty Acid) and abides by all Food and Agriculture Organization codes of conduct.
Seals/Symbols
Eco-Guard(R) Bottle 100% Recycled 100% Recyclable
FISH GEL(TM) Softgels
Formulation
Hexane and solvent-free, molecularly distilledand third-party tested. Guaranteed free of heavy metals, dioxins and PCBs.
100% FishGel(TM) softgel guaranteed free of beef and pork.
GUARANTEE: 100% Natural - Free of artificial colors, flavors, sweeteners, preservatives and other objectionable additives found in vitamin products. Contains no sugar, lactose/dairy, wheat, gluten or yeast.
Suggested/Recommended/Usage/Directions
SUGGESTED USAGE: Take two softgels per day with or between meals. For stronger effects, take two, twice daily.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
2.0-1
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Omega Cardio Performance by Rainbow Light label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Omega Cardio Performance by Rainbow Light
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Omega-3 Fatty Acids
Interacts with375 drugs
DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...
Omega-3 Fatty Acids monograph & interactions- › Eicosapentaenoic Acid
- › Docosahexaenoic Acid
- › Total Omega-3 Fatty Acids
- › Other Omega-3 Fatty Acids
Omega-6 Fatty Acids
No knowninteractions
Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils,...
Omega-6 Fatty Acids monograph & interactions- › Gamma-Linolenic Acid
- › Linoleic Acid
- › Arachidonic Acid
Omega-9 Fatty Acids
- › Oleic Acid
- › Eicosanoic Acid
Vitamin D
Interacts with715 drugs
Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...
Vitamin D monograph & interactionsCoenzyme Q10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q10 monograph & interactionsLemon essential Oil
Interacts with1 drug
Lemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it...
Lemon essential Oil monograph & interactionsPlant Sterol Esters
Purified deep sea Fish Oil
Interacts with327 drugs
Fish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels. The evidence for other heart and health...
Purified deep sea Fish Oil monograph & interactionsOther (inactive) ingredients: Yellow Beeswax, Silica, Softgel Shell. These complete the product’s ingredient list but are not active constituents.
Omega Cardio Performance by Rainbow Light Drug Interactions
Omega Cardio Performance contains 9 ingredients, and 6 of them have known drug interactions. Altogether they interact with 985 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Omega Cardio Performance?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Omega Cardio Performance interact with 985 drugs. Click any drug to see the details.
6 of the 9 ingredients in Omega Cardio Performance interact with drugs. Each result below shows which ingredient is responsible. Vitamin D Omega-3 Fatty Acids purified deep sea Fish Oil Coenzyme Q10 Oleic Acid Lemon essential Oil
AbciximabReoPro
How Abciximab interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Abciximab interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Abrocitinib interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Acarbose interactionOleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Acebutolol interactionPurified Deep Sea Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Purified Deep Sea Fish Oil + Acebutolol interactionCoenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acenocoumarol interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Aspirin interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Aspirin, Caffeine interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Acetaminophen, Aspirin, Caffeine interactionVitamin DCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetaminophen, Ibuprofen interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Purified Deep Sea Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Purified Deep Sea Fish Oil + Acetazolamide interactionOmega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Acetazolamide interactionCoenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Acetohexamide interactionOleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Acetylsalicylic Acid interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Albiglutide interactionOmega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Albiglutide interactionAlginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Alginic Acid, Aluminum Hydroxide interactionAliskirenTekturna
How Aliskiren interacts with Omega Cardio Performance — through 4 ingredients. Tap an ingredient for the detail:
Purified Deep Sea Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Purified Deep Sea Fish Oil + Aliskiren interactionOmega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Aliskiren interactionVitamin DCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Aliskiren interactionCoenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin interactionOmega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin interactionVitamin DCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin, Metformin interactionOleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Oleic AcidAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oleic acid might increase the effects of antidiabetes drugs.
Read the full Oleic Acid + Alogliptin, Pioglitazone interactionOmega-3 Fatty AcidsAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acids + Alogliptin, Pioglitazone interactionVitamin DCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Omega Cardio Performance — through 2 ingredients. Tap an ingredient for the detail:
Omega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Alteplase, Tpa interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Altretamine interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionOmega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Omega Cardio Performance — through 3 ingredients. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionOmega-3 Fatty AcidsAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acids + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionPurified Deep Sea Fish OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Purified Deep Sea Fish Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Omega Cardio Performance — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Aluminum, Magnesium Hydroxide (otc Drug) interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Omega Cardio Performance — through 4 ingredients. Tap an ingredient for the detail:
Purified Deep Sea Fish OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Purified Deep Sea Fish Oil + Ambrisentan interactionOmega-3 Fatty AcidsAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acids + Ambrisentan interactionVitamin DCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Ambrisentan interactionCoenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Omega Cardio Performance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin D
Aluminum
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.
Atorvastatin (Lipitor)
Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.
Calcipotriene (Dovonex)
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.
Diltiazem (Cardizem, Others)
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.
Thiazide Diuretics
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.
Verapamil (Calan, Others)
Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.
Omega-3 Fatty Acids
Anticoagulant/Antiplatelet Drugs
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.
Antidiabetes Drugs
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.
purified deep sea Fish Oil
Antihypertensive Drugs
Theoretically, taking fish oil with antihypertensive drugs might increase the risk of hypotension.
Clinical evidence indicates that fish oils can modestly lower blood pressure and might have additive effects in patients treated with antihypertensives.
Contraceptive Drugs
Theoretically, taking fish oil with contraceptive drugs might decrease the triglyceride-lowering effects of fish oil.
There is some evidence that contraceptive drugs might interfere with the triglyceride lowering effects of fish oils.
Cyclosporine (Neoral, Sandimmune)
Taking fish oil with cyclosporine might increase levels and adverse effects of cyclosporine.
In kidney transplant recipients on a general immunosuppressive regimen, taking omega-3 fatty acids daily seems to increase peak blood levels of cyclosporine when compared with placebo. This increase was as much as 20% after one month. However, the area under the curve was not significantly affected.
Orlistat (Xenical, Alli)
Theoretically, taking fish oil with orlistat might decrease the absorption of fish oil fatty acids.
Orlistat binds lipase in the gastrointestinal tract and reduces fat absorption. Theoretically, taking fish oil with orlistat might decrease absorption of fish oil fatty acids. To avoid this potential interaction, recommend separating administration of orlistat and fish oil by at least 2 hours.
Sirolimus (Rapamune)
Taking fish oil with sirolimus might increase levels and adverse effects of sirolimus.
Pharmacokinetic research shows that omega-3 fatty acids increase exposure to sirolimus in kidney transplant patients on a calcineurin inhibitor-free immunosuppressive regimen. A 25% dose reduction in sirolimus was required to keep patients within the expected trough-concentration window. Researchers hypothesize that this may be due to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.
Tacrolimus (Prograf)
Taking fish oil with tacrolimus might increase levels and adverse effects of tacrolimus.
In a small group of patients, taking fish oil 2.6 grams (Omacor) daily for 4 weeks increased the 8-hour area under the curve of tacrolimus by 25% when compared with baseline. Peak levels were increased by approximately 22%. Researchers hypothesize that this may be due either to an increase in bioavailability or to inhibition of cytochrome P450 3A4 (CYP3A4) by fish oil, although this has not been confirmed in clinical research.
Anticoagulant/Antiplatelet Drugs
Fish oil may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, evidence is conflicting.
While fish oil may not be a potent inhibitor of platelet function, high doses of fish oil might have antiplatelet effects. Theoretically, concomitant use of fish oil with anticoagulant or antiplatelet drugs may increase the risk of bleeding. However, the most rigorous research shows that short-term doses of fish oil 10 grams daily or long-term doses of 1.5 grams daily for up to 52 weeks does not increase the risk of bleeding or affect coagulation parameters in chronically ill and vulnerable patients. Other controlled research shows that fish oil does not affect platelet function or increase the risk of bleeding. Some research even suggests that perioperative fish oil use decreases bleeding risk. Some research suggests fish oil does not have additive antiplatelet effects when combined with aspirin, but other clinical evidence suggests that adding fish oil to low-dose aspirin treatment increases antiplatelet effects in patients who are aspirin-resistant. Also, some clinical research seems to show that fish oil has additive antiplatelet effects when used with aspirin and clopidogrel compared to aspirin and clopidogrel alone.
Platinum Agents
Theoretically, taking fish oil with platinum agents can cause resistance to platinum agents, potentially decreasing their effectiveness.
Platinum-induced fatty acids (PIFAs) are fatty acids secreted from human and mouse stem cells when exposed to platinum-based chemotherapy. Animal research suggests that PIFAs cause resistance to chemotherapy by stimulating lysophospholipid production in the spleen, which interferes with the DNA damage caused by certain chemotherapy drugs. One PIFA, known as 16:4(n-3), has been found in both raw fish and some commercially available fish oil products. Mackerel and herring have high PIFA concentrations, while salmon and tuna have low PIFA concentrations. Levels of PIFA in commercial fish oil products ranged from 0.2- 5.7 microMol. Animal research shows that PIFA-containing fish oil products cause resistance to cisplatin, fluorouracil, irinotecan, and oxaliplatin. It is unclear if all commercially available fish oil products contain PIFAs. Additionally, it is argued that levels of PIFA found in some fish oil products are too low to be of clinical concern. Furthermore, a lack of chemotherapy resistance in countries with high fish intake, such as Greenland, Japan, and Norway, suggest that this interaction may not be clinically significant.
Warfarin (Coumadin)
Fish oil may have antiplatelet effects and might increase the risk of bleeding if used with warfarin.
Fish oil has antiplatelet effects at high doses. Case reports show elevated INR in patients taking warfarin and fish oil 1-2 grams daily. However, some clinical research shows that taking fish oil 3-6 grams daily does not significantly increase INR in patients taking warfarin.
Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Oleic Acid
Antidiabetes Drugs
Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.
Lemon essential Oil
Itraconazole (Sporanox)
Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.
Brand information
Manufacturer and brand details for Omega Cardio Performance, from the product label.
Rainbow Light
See all Rainbow Light products- Name
- Rainbow Light Nutritional Systems
- Street Address
- 125 McPherson St.
- City
- Santa Cruz
- State
- CA
- ZipCode
- 95060
- Web Address
- www.rainbowlight.com
Omega Cardio Performance by Rainbow Light: Common Questions
Does Omega Cardio Performance by Rainbow Light interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Omega Cardio Performance’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Docosahexaenoic Acid (dha)
Interacts with 375 drugsDHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...
Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monographOmega-6 Fatty Acids
Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils, nuts, and seeds. Supplements such as ev...
Read the full Omega-6 Fatty Acids monograph → Herb & supplement monographOleic Acid
Interacts with 86 drugsOleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...
Read the full Oleic Acid monograph → Herb & supplement monographVitamin D
Interacts with 715 drugsVitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...
Read the full Vitamin D monograph → Herb & supplement monographCoenzyme Q10
Interacts with 198 drugsCoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...
Read the full Coenzyme Q10 monograph → Herb & supplement monographLemon
Interacts with 1 drugLemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it can support hydration and a healthy diet...
Read the full Lemon monograph → Herb & supplement monographFish Oil
Interacts with 327 drugsFish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels. The evidence for other heart and health benefits is mixed, and it is generally...
Read the full Fish Oil monograph →Sources & How We Checked
Omega Cardio Performance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 313 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Docosahexaenoic Acid (dha) 49 references
- Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
- Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
- Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
- Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
- Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
- Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
- Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
- Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
- Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
- Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
- Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
- Hawkes JS, Bryan DL, Makrides M, et al. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. Am J Clin Nutr 2002;75:75
- Uauy R, Hoffman DR, Mena P, et al. Term infant studies of DHA and ARA supplementation on neurodevelopment: Results of randomized controlled trials. J Pediatr 2003;143:S17-25. PubMed
- Decsi, T., Campoy, C., and Koletzko, B. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Adv.Exp Med Biol 2005;569:109-113. PubMed
- Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
- Otto, S. J., van Houwelingen, A. C., and Hornstra, G. The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. Prostaglandins Le PubMed
- Helland, I. B., Saugstad, O. D., Smith, L., Saarem, K., Solvoll, K., Ganes, T., and Drevon, C. A. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001;108(5):E82. PubMed
- Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
- Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
- Jensen, C. L., Voigt, R. G., Prager, T. C., Zou, Y. L., Fraley, J. K., Rozelle, J. C., Turcich, M. R., Llorente, A. M., Anderson, R. E., and Heird, W. C. Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed
- Theobald, H. E., Goodall, A. H., Sattar, N., Talbot, D. C., Chowienczyk, P. J., and Sanders, T. A. Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women. J Nutr 2007;137(4):973-978.
- Mischoulon D, Best-Popescu C, Laposata M, et al. A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder. Eur Neuropsychopharmacol. 2008;18(9):639-645. PubMed
- Birch EE, Carlson SE, Hoffman DR, et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexa
- Carlson SE, Colombo J, Gajewski BJ, Gustafson KM, Mundy D, Yeast J, Georgieff MK, Markley LA, Kerling EH, Shaddy DJ. DHA supplementation and pregnancy outcomes. Am J Clin Nutr. 2013 Apr;97(4):808-15. PubMed
- Escamilla-Nuñez MC, Barraza-Villarreal A, Hernández-Cadena L, Navarro-Olivos E, Sly PD, Romieu I. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children. Chest. 2014 Aug;146(2):373-82. PubMed
- Fu YQ, Zheng JS, Yang B, Li D. Effect of individual omega-3 fatty acids on the risk of prostate cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. J Epidemiol. 2015;25(4):261-74. PubMed
- Imhoff-Kunsch B, Stein AD, Villalpando S, Martorell R, Ramakrishnan U. Docosahexaenoic acid supplementation from mid-pregnancy to parturition influenced breast milk fatty acid concentrations at 1 month postpartum in Mexican women. J Nutr. 2011 Feb;141(2): PubMed
- Judge MP, Cong X, Harel O, Courville AB, Lammi-Keefe CJ. Maternal consumption of a DHA-containing functional food benefits infant sleep patterning: an early neurodevelopmental measure. Early Hum Dev. 2012 Jul;88(7):531-7. PubMed
- Mulder KA, King DJ, Innis SM. Omega-3 fatty acid deficiency in infants before birth identified using a randomized trial of maternal DHA supplementation in pregnancy. PLoS One. 2014 Jan 10;9(1):e83764. PubMed
- Richardson AJ, Burton JR, Sewell RP, Spreckelsen TF, Montgomery P. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). PLoS One. 2012;7(9):e43909. PubMed
- Drugs in Pregnancy and Lactation 2012;25(4);3-4
- FDA announces qualified health claims for omega-3 fatty acids. Available at: https://www.fda.gov/Food/LabelingNutrition/ucm072756.htm. Accessed April 15 2019.
- Breastfeeding and the use of human milk. Section on Breastfeeding. Pediatrics. 2012;129(3):e827-41. PubMed
- Zhang Z, Fulgoni VL, Kris-Etherton PM, Mitmesser SH. Dietary Intakes of EPA and DHA Omega-3 Fatty Acids among US Childbearing-Age and Pregnant Women: An Analysis of NHANES 2001-2014. Nutrients. 2018;10(4). PubMed
- Montgomery P, Spreckelsen TF, Burton A, Burton JR, Richardson AJ. Docosahexaenoic acid for reading, working memory and behavior in UK children aged 7-9: A randomized controlled trial for replication (the DOLAB II study). PLoS One. 2018;13(2):e0192909. PubMed
- Marc I, Piedboeuf B, Lacaze-Masmonteil T, et al. Effect of maternal docosahexaenoic acid supplementation on bronchopulmonary dysplasia-free survival in breastfed preterm infants: A randomized clinical trial. JAMA. 2020;324(2):157-167. PubMed
- Fougère H, Bilodeau JF, Lavoie PM, et al. Docosahexaenoic acid-rich algae oil supplementation on breast milk fatty acid profile of mothers who delivered prematurely: a randomized clinical trial. Sci Rep 2021;11(1):21492. PubMed
- Garmendia ML, Casanello P, Flores M, Kusanovic JP, Uauy R. The effects of a combined intervention (docosahexaenoic acid supplementation and home-based dietary counseling) on metabolic control in obese and overweight pregnant women: the MIGHT study. Am J O PubMed
- Christifano DN, Gustafson KM, Carlson SE, et al. Maternal docosahexaenoic acid exposure needed to achieve maternal-newborn EQ. Nutrients 2022;14(16):3300. PubMed
- Vizzari G, Morniroli D, Alessandretti F, et al. Comparative analysis of docosahexaenoic acid (DHA) content in mother's milk of term and preterm mothers. Nutrients 2022;14(21):4595. PubMed
- Yang Y, Li G, Li F, et al. Impact of DHA from algal oil on the breast milk DHA levels of lactating women: A randomized controlled trial in China. Nutrients 2022;14(16):3410. PubMed
See these in context on the Docosahexaenoic Acid (dha) monograph →
Omega-6 Fatty Acids 20 references
- Godley PA. Essential fatty acid consumption and risk of breast cancer. Breast Cancer Res Treat 1995;35:91-5. PubMed
- Newcomer LM, King IB, Wicklund KG, Stanford JL. The association of fatty acids with prostate cancer risk. Prostate 2001;47:262-8. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate. Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/books/03 DOI
- Colter, A. L., Cutler, C., and Meckling, K. A. Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study. Nutr J 2008;7:8. PubMed
- Yamada, T., Strong, J. P., Ishii, T., Ueno, T., Koyama, M., Wagayama, H., Shimizu, A., Sakai, T., Malcom, G. T., and Guzman, M. A. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atheroscler
- Conklin, S. M., Manuck, S. B., Yao, J. K., Flory, J. D., Hibbeln, J. R., and Muldoon, M. F. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Psychosom.Med. 2007;69(9):932-934.
- Richardson, A. J., Cyhlarova, E., and Ross, M. A. Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults. Prostaglandins Leukot.Essent.Fatty Acids 2003;69(6):461-466. PubMed
- Assies, J., Lok, A., Bockting, C. L., Weverling, G. J., Lieverse, R., Visser, I., Abeling, N. G., Duran, M., and Schene, A. H. Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins Leukot.Es PubMed
- Chiplonkar, S. A., Agte, V. V., Tarwadi, K. V., Paknikar, K. M., and Diwate, U. P. Micronutrient deficiencies as predisposing factors for hypertension in lacto-vegetarian Indian adults. J Am Coll.Nutr 2004;23(3):239-247. PubMed
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