Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Organic Lemon Balm Ingredients & Drug Interactions

by Traditional Medicinals

Organic Lemon Balm label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Lemon Balm against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Lemon Balm is a dietary supplement by Traditional Medicinals with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lemon Balm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Organic Lemon Balm by Traditional Medicinals

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Lemon Balm by Traditional Medicinals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Organic Lemon Balm by Traditional Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “All Herbal Ingredients” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains a single active ingredient: lemon balm, a leafy herb from the mint family. The ingredient list shows no inactive fillers or binders — it's just the herb itself in tablet or pill form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Calms nervous system and supports digestion.
  • We looked for evidence on: Anxiety, Stress, Dyspepsia, Insomnia, Irritable bowel syndrome (IBS), Nervousness — and 3 related terms.
  • The strongest evidence on file: Lemon Balm is rated "Possibly Effective" for Stress (Natural Medicines).
  • Also on file: Lemon Balm is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Dyspepsia, Insomnia, Irritable bowel syndrome (IBS).

Lemon balm is rated Possibly Effective for cold sores (herpes labialis) and for easing stress and depression, according to our evidence data. That means there's some clinical support, but the evidence isn't yet definitive.

If you're looking at this for one of those uses, it may help, but it's not a sure thing.

The evidence, ingredient by ingredient Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lemon balm is generally well tolerated for short-term use in most healthy adults, though we don't have enough long-term safety data at higher doses to know what happens with extended use. The most commonly reported side effects — dizziness and sedation — don't seem to occur more often with the herb than with placebo in trials.

One very rare case of heart rhythm problems has been reported, though it involved a product with multiple ingredients, so it's unclear whether lemon balm alone was the cause. During pregnancy, there isn't enough reliable safety data, so it's best avoided unless your doctor advises otherwise.

While breastfeeding, safety information is limited; talk to your doctor before using it.

Side effects, ingredient by ingredient Lemon Balm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lemon Balm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 264 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Organic Lemon Balm, double-check if you take any CNS depressants — sedatives, sleeping pills, anxiety medications, or strong pain relievers — as the herb can add to their drowsy effects. Also flag if you're on thyroid hormone replacement therapy, since lemon balm may interfere with it.

Use the medication checker on this page to verify your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lemon balm may be worth considering if you're dealing with cold sores, stress, or low mood and want an herbal option. If you take sedating drugs or thyroid replacement therapy, check with us or your pharmacist first — lemon balm could amplify drowsiness or reduce how well your thyroid medication works.

It's generally well tolerated for short-term use, but long-term safety at high doses isn't well studied.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Lemon Balm, straight from the product label.

Brand Traditional Medicinals
Net contents 0.85 Ounce(s); 24 Gram(s); 16 Wrapped Tea Bag(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 306985
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Lemon Balm by Traditional Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tea Bag(s)
Maximum serving Sizes:
1 Tea Bag(s)
Servings per container
16
IngredientAmount% DV
Calories0 Calorie(s)--
Lemon Balm1500 mg--
All Herbal Ingredients0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Use this number on all correspondence related to this product SEP2025B0013281 Herbs that work From field to cup, we make sure our teas deliver the benefits of these amazing plants. To deliver consistent high quality teas, we source organically farmed or organically wild-collected herbs from ethical trading partnerships, seeking out medicinal-grade plants. Only a small fraction of the world's herb supply meets our high quality standards. Learn more about our farming communities and our work to create positive social impact at traditionalmedicinals.com

Formulation

Daily herbal Calms the nervous system & supports digestion

Caffeine free

Certified organic by CCOF. All ingredients Certified Organic.

Non GMO Project Verified nongmoproject.org

Herbal power Calms the nervous system and supports digestion. Taste Pleasantly mild, with subtle citrus notes.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Non GMO Project Verified nongmoproject.org OK (Kosher) Certified B Corporation

Formula

OK (Kosher)

Plant story With broad leaves and a pleasing lemony scent, lemon balm is traditionally used to support digestion and relieve nervous tension. Native to Southern Europe, people have been cultivating and using this plant for thousands of years. Known as the "bringer of gladness," it's sure to brighten your day.

Precautions

This product may cause drowsiness. Exercise caution if you are driving or involved in activities requiring mental alertness.

Consult your healthcare practitioner prior to use if pregnant or breastfeeding.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

To enjoy Pour 8 oz. freshly boiled water over 1 tea bag. Cover & steep for 5-10 min. Squeeze & remove tea bag to ensure maximum goodness. Enjoy 3 cups per day.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Lemon Balm by Traditional Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Lemon Balm label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Lemon Balm by Traditional Medicinals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tea Bag(s) Dosage formTablet Or Pill Servings per container16 Amounts shown are per serving.

All Herbal Ingredients

0 NP per serving
Interaction report

Organic Lemon Balm by Traditional Medicinals Drug Interactions

Want to check YOUR meds against Organic Lemon Balm?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
264Drugs
264 Moderate

Ingredients driving the most interactions

Lemon Balm 264

Individual Drug Interactions

The ingredients in Organic Lemon Balm interact with 264 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Lemon Balm interact with drugs. Each result below shows which ingredient is responsible. Lemon Balm

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Lemon Balm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lemon Balm2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
Lemon Balm full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Lemon Balm, from the product label.

Traditional Medicinals

See all Traditional Medicinals products
Name
Traditional Medicinals
Street Address
4515 Ross Road
City
Sebastopol
State
CA
ZipCode
95472
Web Address
traditionalmedicinals.com
Pharmacist Counseling Corner

Organic Lemon Balm by Traditional Medicinals: Common Questions

Does Organic Lemon Balm by Traditional Medicinals interact with any medications?
Yes. Based on its ingredients, Organic Lemon Balm has a known interaction with 264 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Lemon Balm contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take lemon balm if I'm pregnant?
There isn't enough reliable safety data to know, so it's best avoided during pregnancy unless your doctor advises otherwise. Talk to your doctor or pharmacist about whether it's right for you.
What is lemon balm actually used for?
Lemon balm is rated Possibly Effective for cold sores and for easing stress and depression. There's some clinical evidence it may help with these, though the proof isn't yet conclusive.
Will lemon balm make me drowsy?
Dizziness and sedation have been reported with lemon balm, but they don't appear to happen more often than with placebo in clinical trials. Most people don't experience these effects, though they're possible.
Is it safe to take lemon balm long-term?
Lemon balm is generally well tolerated for short-term use, but we don't have solid safety data for long-term use at high doses. If you're thinking about using it regularly, check with your pharmacist or doctor.
Can I take lemon balm with alcohol?
Clinical research shows that lemon balm used with alcohol doesn't affect reaction time or cognitive performance. However, if you're also on a CNS depressant medication, combining all three could increase drowsiness — ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Lemon Balm is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Lemon Balm label
Go deeper

The Full Monographs Behind Organic Lemon Balm’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

Organic Lemon Balm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team