Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Hemp+Herb Mental Focus Ingredients & Drug Interactions

by Traditional Medicinals

Hemp+Herb Mental Focus label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hemp+Herb Mental Focus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hemp+Herb Mental Focus is a dietary supplement by Traditional Medicinals with 6 active ingredients. Its ingredients are commonly taken for irritable bowel syndrome (ibs), indigestion and gas, nausea.Based on those ingredients, 1,456 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eleuthero Aqueous Root Extract, Hemp Herb Soft Extract, Peppermint. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hemp+Herb Mental Focus by Traditional Medicinals

Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp+Herb Mental Focus by Traditional Medicinals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hemp+Herb Mental Focus by Traditional Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,595 mg) without saying how much of each component you get.

Hemp+Herb Mental Focus is a tea blend with 6 active ingredients. The proprietary blend contains peppermint and spearmint (both mint herbs), eleuthero (an adaptogenic root extract), and hemp herb soft extract, along with guayusa and roasted mate (caffeinated botanicals).

Inactive ingredients—gum arabic, sunflower lecithin, and quillaia bark extract—act as binders and stabilizers in the tea bags.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Mental focus and cognitive clarity.
  • We looked for evidence on: Cognitive function, Age-related cognitive decline, Anxiety, Stress, Fatigue, Alertness — and 1 related terms.
  • The closest evidence on file: Peppermint is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety (Natural Medicines).
  • Also on file: Peppermint is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Fatigue, Stress.
  • Also on file: Spearmint is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline, Cognitive function.

The evidence for this blend's effectiveness is mixed. Peppermint is likely effective for irritable bowel syndrome and possibly effective for indigestion and nausea.

Eleuthero is possibly effective for genital herpes but insufficient evidence supports its use for fatigue, cognitive decline, or other conditions this blend may target. Spearmint has insufficient reliable evidence for any of the uses listed in our data—including cognitive function and IBS.

Hemp's effectiveness is not established in the data we hold. Overall, the strongest evidence backs peppermint's digestive benefits, not mental focus.

The evidence, ingredient by ingredient Peppermint Spearmint Eleuthero Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Peppermint and peppermint leaf tea are generally well tolerated in normal amounts; concentrated peppermint oil should be used carefully. Spearmint is generally safe orally and in food or tea amounts.

Eleuthero is generally well tolerated short-term, but long-term safety data are limited, and it carries neurological risks (nervousness, anxiety, irritability) especially at higher doses. Hemp products are generally well tolerated in food amounts; concentrated extracts have less safety data.

Rare serious effects reported with hemp include anaphylaxis and, in one case, elevated liver enzymes. Peppermint's most common side effects are abdominal pain, belching, diarrhea, dry mouth, and heartburn.

Eleuthero may raise blood pressure and heart rate in some people.

Side effects, ingredient by ingredient Peppermint Spearmint Eleuthero Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Peppermint, Spearmint, Eleuthero, Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,457 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take digoxin or other heart medications (eleuthero can raise digoxin levels—Moderate), anticoagulants or antiplatelet drugs like warfarin or clopidogrel (spearmint and hemp theoretically increase bleeding risk—Moderate and Minor), medications that cause drowsiness or CNS effects (spearmint—Moderate), immunosuppressants (eleuthero—Moderate), antidiabetes drugs (eleuthero—Moderate), liver-metabolized medications (peppermint, eleuthero, hemp—Moderate and Minor), or estrogen therapy (hemp—Moderate). Because several drug-metabolizing enzyme interactions have not yet been observed in humans, documented interactions in the lab don't guarantee they'll occur in your body, but they warrant a conversation with your healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This blend combines digestive herbs (peppermint, spearmint) with adaptogenic and caffeinated botanicals. Peppermint has solid evidence for digestive issues, but the product's mental-focus claims aren't well supported in the data we hold.

Because it contains four ingredients with documented drug interactions—including a serious one with digoxin—check your medications with your pharmacist or doctor before starting, especially if you take heart, blood pressure, blood-thinning, or diabetes medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hemp+Herb Mental Focus, straight from the product label.

Brand Traditional Medicinals
Net contents 0.99 Ounce(s); 28 Gram(s); 16 Wrapped Tea Bag(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 275004
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hemp+Herb Mental Focus by Traditional Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tea Bag(s)
Maximum serving Sizes:
1 Tea Bag(s)
Servings per container
16
IngredientAmount% DV
Proprietary Blend1595 mg--
Calories0 Calorie(s)--
Peppermint0 NP--
Spearmint0 NP--
Eleuthero Aqueous Root Extract30 mg--
Hemp Herb Soft Extract20 mg--
organic Guayusa0 NP--
Mate, Roasted0 NP--

Other ingredients: Gum Arabic, Sunflower Lecithin, Quillaia Bark Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Broad spectrum hemp extract + Guayusa mint 20 mg Hemp extract per serving

Precautions

Contains caffeine

Consult your physician before use if you are taking prescription drugs, if you have insomnia, heart disease, or high blood pressure. Do not use if you are pregnant or breastfeeding, if you have symptoms of liver disease, including elevated liver enzymes, or if you are allergic to any of the ingredients.

Consult your physician before use if you are taking prescription drugs, if you have insomnia, heart disease, or high blood pressure. Do not use if you are pregnant or breastfeeding, if you have symptoms of liver disease, including elevated liver enzymes, or if you are allergic to any of the ingredients.

For adult use only.

Keep out of reach of children.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Certified Organic CCOF Organic is Non-GMO & more

Certified B Corporation

Formulation

88% Certified Organic Ingredients.

Herbal Power Helps support mental alertness Taste Minty and lightly roasted. Plant Story Guayusa and yerba mate, native to South America, are plants used to promote alertness due to their naturally occurring caffeine content. Our herbalists have formulated this blend to include eleuthero and broad-spectrum hemp extract. Designed to help sustain energy levels, this tea is a great pick me up any time of day.

Certified Organic CCOF Organic is Non-GMO & more

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

To Enjoy Pour 8 oz. freshly boiled water over 1 tea bag. Cover & steep for 10-15min. Squeeze tea bag to ensure maximum goodness. Enjoy 2 cups daily.

Daily herbal

General Statements

Herbs that work From field to cup, we make sure our teas deliver the benefits of these amazing plants. We do this by sourcing high quality farmed or wild-collected herbs from ethical trading partnerships, seeking out medicinal-grade plants. Only a small fraction of the world's herb supply meets our high quality standards.

Learn more about our farming communities and the work of our foundation on our website. traditionalmedicinals.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hemp+Herb Mental Focus by Traditional Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hemp+Herb Mental Focus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hemp+Herb Mental Focus by Traditional Medicinals

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tea Bag(s) Dosage formOther (e.g. Tea Bag) Servings per container16 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1595 mg per serving

Eleuthero Aqueous Root Extract

Interacts with
1,140 drugs
30 mg per serving

Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence beh...

Eleuthero Aqueous Root Extract monograph & interactions

Hemp Herb Soft Extract

Interacts with
938 drugs
20 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Hemp Herb Soft Extract monograph & interactions

Other (inactive) ingredients: Gum Arabic, Sunflower Lecithin, Quillaia Bark Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hemp+Herb Mental Focus by Traditional Medicinals Drug Interactions

Want to check YOUR meds against Hemp+Herb Mental Focus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,456Drugs
1,312 Moderate 144 Minor

Ingredients driving the most interactions

Eleuthero Aqueous Root Extract 1,140
Hemp Herb Soft Extract 938
Peppermint 796
Spearmint 579

Individual Drug Interactions

The ingredients in Hemp+Herb Mental Focus interact with 1,456 drugs. Click any drug to see the details.

4 of the 6 ingredients in Hemp+Herb Mental Focus interact with drugs. Each result below shows which ingredient is responsible. Eleuthero Aqueous Root Extract Hemp Herb Soft Extract Peppermint Spearmint

Each ingredient & the kinds of drugs it affects

For each ingredient in Hemp+Herb Mental Focus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Eleuthero Aqueous Root Extract10 drug types · 1,140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, eleuthero may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that a constituent of eleuthero, dihydroxybenzoic acid, appears to inhibit platelet aggregation. Concomitant use with anticoagulant or antiplatelet drugs might increase the risk of bleeding. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eleuthero might have additive effects when used with antidiabetes drugs.
Animal research suggests that certain constituents of eleuthero have hypoglycemic activity in both healthy and diabetic animals. A small study in adults with type 2 diabetes also shows that taking eleuthero for 3 months can lower blood glucose levels. However, one very small study in healthy individuals shows that taking powdered eleuthero 3 grams, 40 minutes prior to a 75-gram oral glucose tolerance test, significantly increases postprandial blood glucose levels when compared with placebo. These contradictory findings might be due to patient-specific variability and variability in active ingredient ratios.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP1A2.
In vitro and animal research suggest that standardized extracts of eleuthero inhibit CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2C9.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2C9. This effect has not been reported in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Eleuthero might increase serum digoxin levels and increase the risk of side effects.
In one case report, a 74-year-old male who was stabilized on digoxin presented with an elevated serum digoxin level after starting an eleuthero supplement, without symptoms of toxicity. After stopping the supplement, serum digoxin levels returned to normal. It is not clear whether this was due to a pharmacokinetic interaction or to interference with the digoxin assay. Although the product was found to be free of digoxin and digitoxin, it was not tested for other contaminants.

Likelihood Unlikely Evidence D
Immunosuppressants

Theoretically, eleuthero might interfere with immunosuppressive drugs because of its immunostimulant activity.
Animal and in vitro research shows that eleuthero extracts have immunomodulatory effects, including increasing cellular and humoral activity.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, eleuthero might increase levels of P-glycoprotein substrates.
In vitro research suggests that eleuthero can inhibit the multi-drug transporter protein, P-glycoprotein. However, it is too soon to tell if this is clinically important. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP2D6.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP2D6. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP2D6 drug metabolism.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eleuthero might increase levels of drugs metabolized by CYP3A4.
In vitro and animal research suggest that standardized extracts of eleuthero might inhibit CYP3A4. However, research in healthy human volunteers has found that taking eleuthero 485 mg twice daily for 14 days does not inhibit CYP3A4 drug metabolism.

Likelihood Unlikely Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, eleuthero might decrease levels of drugs metabolized by OATP.
In vitro research suggests that eleuthero inhibits OATP2B1, which might reduce the bioavailability of oral drugs that are substrates of OATP2B1. Due to the weak inhibitory effect identified in this study, this interaction is not likely to be clinically significant.

Likelihood Possible Evidence D
Eleuthero Aqueous Root Extract full monograph & interactions

Hemp Herb Soft Extract6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Hemp Herb Soft Extract full monograph & interactions

Peppermint5 drug types · 796 drugs

Cyclosporine (Neoral, Sandimmune)

Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.

Likelihood Possible Evidence B
Peppermint full monograph & interactions

Spearmint2 drug types · 579 drugs

Cns Depressants

Theoretically, spearmint might alter the sedative effects of CNS depressants.
Animal research suggests that (-)-carvone, a major constituent of spearmint, has sedative effects. However, in humans, chewing spearmint-flavored gum induced arousal effects.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, high doses of spearmint might increase the risk of liver damage when taken with hepatotoxic drugs.
Animal research suggests that drinking spearmint tea for 30 days can increase markers of liver damage, including aspartate aminotransferase (AST) and alanine aminotransferase (ALT), and cause liver degeneration and necrosis, in a dose-dependent manner. This effect has not been reported in humans.

Likelihood Possible Evidence D
Spearmint full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hemp+Herb Mental Focus, from the product label.

Traditional Medicinals

See all Traditional Medicinals products
Name
Traditional Medicinals
Street Address
4515 Ross Road
City
Sebastopol
State
CA
ZipCode
95472
Web Address
traditionalmedicinals.com
Pharmacist Counseling Corner

Hemp+Herb Mental Focus by Traditional Medicinals: Common Questions

Does Hemp+Herb Mental Focus by Traditional Medicinals interact with any medications?
Yes. Based on its ingredients, Hemp+Herb Mental Focus has a known interaction with 1,456 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hemp+Herb Mental Focus contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is peppermint safe to drink as tea?
Peppermint tea in normal amounts is generally well tolerated. The caution applies to concentrated peppermint oil supplements; tea is typically fine unless your doctor advises otherwise.
Does this product actually help with mental focus?
The data we hold show insufficient evidence to support spearmint or hemp for cognitive function, and eleuthero's evidence for mental focus is not established. Peppermint has solid evidence for digestive benefits, not focus.
What are the most common side effects?
Peppermint may cause abdominal pain, belching, diarrhea, dry mouth, and heartburn. Eleuthero may cause nervousness, anxiety, irritability, and digestive upset, especially at higher doses.
Is it safe to take this during pregnancy?
Peppermint is likely safe in pregnancy. Spearmint carries conflicting data—it's rated both likely safe and possibly unsafe in pregnancy, so talk with your doctor. Eleuthero is best avoided in pregnancy due to insufficient safety data. No pregnancy data are on file for hemp, so discuss it with your provider.
Can I take this with my blood thinner?
Spearmint and hemp both theoretically increase bleeding risk with anticoagulants or antiplatelet drugs. Eleuthero also carries a moderate risk. Check with your doctor or pharmacist before starting.
What is eleuthero and why is it in this blend?
Eleuthero (also called Siberian ginseng) is an adaptogenic root extract—a plant used to support resilience and energy. It has possibly effective evidence for genital herpes but insufficient evidence for mental focus or fatigue.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hemp+Herb Mental Focus label
Go deeper

The Full Monographs Behind Hemp+Herb Mental Focus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Peppermint

Interacts with 796 drugs

Peppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...

Read the full Peppermint monograph → Herb & supplement monograph

Spearmint

Interacts with 579 drugs

Spearmint is a common culinary mint that is generally safe in food and tea amounts. Early research suggests possible benefits for digestion, mild hormone-related issues (such as excess facia...

Read the full Spearmint monograph → Herb & supplement monograph

Eleuthero

Interacts with 1,140 drugs

Eleuthero is an herb traditionally used as an 'adaptogen' to fight fatigue, boost energy, and help the body handle stress. The scientific evidence behind these uses is limited and mixed, so...

Read the full Eleuthero monograph → Herb & supplement monograph

Hemp

Interacts with 938 drugs

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...

Read the full Hemp monograph →
Sources

Sources & How We Checked

Hemp+Herb Mental Focus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 97 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Peppermint 41 references
  1. Liu JH, Chen GH, Yeh HZ, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol 1997;32:765-8. PubMed
  2. Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol 1998;93:1131-5. PubMed
  3. Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr 2001;138:125-8. PubMed
  4. Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled, double-blind equivalence study. Arzneimittel
  5. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
  6. Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
  7. Morton CA, Garioch J, Todd P, et al. Contact sensitivity to menthol and peppermint in patients with intra-oral symptoms. Contact Dermatitis 1995;32:281-4. PubMed
  8. May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
  9. Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract 1986;40:292-3. DOI
  10. Rees WD, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br Med J 1979;2:835-6. PubMed
  11. Davies SJ, Harding LM, Baranowski AP. A novel treatment of postherpetic neuralgia using peppermint oil. Clin J Pain 2002;18:200-2. PubMed
  12. Weston CF. Anal burning and peppermint oil. Postgrad Med J 1987;63:717. PubMed
  13. Dresser GK, Wacher V, Wong S, et al. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther 2002;72:247-55. PubMed
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Spearmint 20 references
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Eleuthero 24 references
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Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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