Major interaction on record — check this product against your medications before combining. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Peak ATP With GlycoCarn Ingredients & Drug Interactions

by Life Extension

Peak ATP With GlycoCarn label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Peak ATP With GlycoCarn against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Peak ATP With GlycoCarn is a dietary supplement by Life Extension with 2 active ingredients. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 47 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Peak ATP Adenosine 5'-Triphosphate Disodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Peak ATP With GlycoCarn by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with Peak ATP With GlycoCarn by Life Extension — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Peak ATP With GlycoCarn by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: Peak ATP (adenosine 5'-triphosphate disodium), which is a cellular energy compound, and GlycoCarn (glycine propionyl-L-carnitine hydrochloride), an amino acid derivative. The remaining ingredients are inactive — vegetable cellulose, microcrystalline cellulose, stearic acid, vegetable stearate, and silica — which serve as capsule material and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Adenosine's overall clinical evidence instead.

Strong

Strong clinical evidence supports Adenosine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Cardiovascular disease diagnosis — rated "Effective" (Natural Medicines).
  • On file: Paroxysmal supraventricular tachycardia — rated "Effective" (Natural Medicines).
  • On file: Cachexia — rated "Possibly Effective" (Natural Medicines).

Peak ATP is rated effective for two clinical uses: paroxysmal supraventricular tachycardia (a type of rapid heartbeat that starts and stops suddenly) and for cardiovascular disease diagnosis. These ratings come from the injectable prescription form; the evidence for the oral supplement form is more limited.

We hold no effectiveness data for GlycoCarn in our files.

The evidence, ingredient by ingredient Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This is where you need to be careful. The prescription injectable form of adenosine is powerful and carries real cardiovascular and respiratory risks — chest pain, dizziness, shortness of breath, facial flushing, headache, low blood pressure, nausea, and heart rhythm problems are documented.

The oral supplement form has not been thoroughly evaluated for safety, and the facts note there isn't enough safety information to recommend it. There is also not enough data to know whether this product is safe during breastfeeding, so it should be avoided while nursing.

Talk with your doctor or pharmacist before taking this supplement, especially if you have heart disease or take heart medications.

Side effects, ingredient by ingredient Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take dipyridamole (Persantine) — a Major interaction risk — or carbamazepine (Tegretol) — Moderate risk. Also mention any use of methylxanthines like caffeine, aminophylline, or theophylline, which can interfere with how this supplement works.

Because we couldn't check one of the two ingredients for drug interactions, running your full medication list through the tool on this page is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Peak ATP is used in medical settings to treat certain heart rhythm problems and to help diagnose heart disease, but the oral supplement form lacks the safety testing the injectable prescription version has undergone. If you take heart medications — particularly dipyridamole, carbamazepine, or caffeine-based drugs — you'll need to check with your doctor or pharmacist before starting this product.

Because the safety data is limited for oral use, confirm with your own healthcare provider whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Peak ATP With GlycoCarn, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870132363
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2016
DSLD ID 59103
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Peak ATP With GlycoCarn by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
737870132363
IngredientAmount% DV
Peak ATP Adenosine 5'-Triphosphate Disodium100 mg--
GlycoCarn Glycine Propionyl-L-Carnitine Hydrochloride500 mg--

Other ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Stearic Acid, Vegetable Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Suggested/Recommended/Usage/Directions

Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) vegetarian capsule twice daily on an empty stomach, or as recommended by a healthcare practitioner.

Brand IP Statement(s)

The pioneers in carnitine research, Sigma-tau HealthScience Inc., offer GPLC with increased carnitine bioavailability, targetin muscles, heart, and blood vessels. Patented PEAK ATP is the first orally active form of the energy producing molecule adenosine triphosphate (ATP).

PEAK ATP is a registered trademark of technical Sourcing International, Inc. and is protected by U.S. Patent Nos. 5,227,371 and 5,049,372 and other patents pending. GlyCarn is a registered trademark of Sigma-tau HealthScience, Inc. and is protected by U.S. Patent No. 6,703,042 B1.

Storage

Store tightly closed in a cool, dry place.

Precautions

WARNINGS: -Keep out of reach of children.

-DO NOT EXCEED THE RECOMMENDED DOSE. -Do not purchase if outer seal is broken or damaged.

-When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

FDA Disclaimer Statement

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

Q01323D

Formula

Promotes Healthy Endothelial Function*

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Peak ATP With GlycoCarn by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Peak ATP With GlycoCarn label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Peak ATP With GlycoCarn by Life Extension

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Peak ATP Adenosine 5'-Triphosphate Disodium

Interacts with
47 drugs
100 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

Peak ATP Adenosine 5'-Triphosphate Disodium monograph & interactions

GlycoCarn Glycine Propionyl-L-Carnitine Hydrochloride

500 mg per serving

Other (inactive) ingredients: Vegetable Cellulose, Microcrystalline Cellulose, Stearic Acid, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Peak ATP With GlycoCarn by Life Extension Drug Interactions

Want to check YOUR meds against Peak ATP With GlycoCarn?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
47Drugs
2 Major 1 Moderate 44 Minor

Ingredients driving the most interactions

Peak ATP Adenosine 5'-Triphosphate Disodium 47

Individual Drug Interactions

The ingredients in Peak ATP With GlycoCarn interact with 47 drugs. Click any drug to see the details.

1 of the 2 ingredients in Peak ATP With GlycoCarn interact with drugs. Each result below shows which ingredient is responsible. Peak ATP Adenosine 5'-Triphosphate Disodium

Each ingredient & the kinds of drugs it affects

For each ingredient in Peak ATP With GlycoCarn with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Peak ATP Adenosine 5'-Triphosphate Disodium3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Peak ATP Adenosine 5'-Triphosphate Disodium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Peak ATP With GlycoCarn, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
866-280-2852
Web Address
www.lef.org
Pharmacist Counseling Corner

Peak ATP With GlycoCarn by Life Extension: Common Questions

Does Peak ATP With GlycoCarn by Life Extension interact with any medications?
Yes. Based on its ingredients, Peak ATP With GlycoCarn has a known interaction with 47 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Peak ATP With GlycoCarn contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does Peak ATP actually do in the body?
Peak ATP is adenosine 5'-triphosphate — a chemical that's naturally made inside your cells to power energy production. In prescription form given intravenously, it's used to treat certain rapid heartbeats and to help test how well the heart works. The oral supplement form hasn't been studied as thoroughly for safety and effectiveness.
Can I take this if I'm on heart medications?
That depends on which ones. Dipyridamole and carbamazepine interact with Peak ATP in ways that concern us, and so does caffeine. Your doctor or pharmacist needs to review your complete medication list before you start — don't begin this on your own if you take heart drugs.
Is this safe to take long-term?
The facts note there's limited safety data for the oral supplement form, which is different from the well-studied prescription injectable. Before taking it long-term, talk with your doctor or pharmacist about what the evidence shows and whether it's appropriate for your situation.
What's GlycoCarn, and what does it do?
GlycoCarn is glycine propionyl-L-carnitine hydrochloride, an amino acid derivative. We don't have effectiveness or interaction data on file for it, so ask your pharmacist if they can tell you more about its role in this formula.
Is this okay to take while breastfeeding?
The safety information for Peak ATP during breastfeeding isn't established, so it's best avoided while nursing. Talk with your doctor or pharmacist about whether there are other options that are better studied in this situation.
Does this contain any fillers or additives?
Yes — the capsule and formula contain vegetable cellulose, microcrystalline cellulose, stearic acid, vegetable stearate, and silica, which are standard inactive ingredients that hold the product together and make it a capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Peak ATP With GlycoCarn is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Peak ATP With GlycoCarn label
Go deeper

The Full Monographs Behind Peak ATP With GlycoCarn’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph →
Sources

Sources & How We Checked

Peak ATP With GlycoCarn's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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