Interactions on record — worth a quick check against your medications. Based on 8 of 12 ingredients. Check your meds →
Dietary supplement

PlantFusion Unflavored Ingredients & Drug Interactions

by NutraFusion Nutritionals

PlantFusion Unflavored label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PlantFusion Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PlantFusion Unflavored is a dietary supplement by NutraFusion Nutritionals with 12 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 574 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Artichoke Protein, Sodium, Bromelain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PlantFusion Unflavored by NutraFusion Nutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with PlantFusion Unflavored by NutraFusion Nutritionals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of PlantFusion Unflavored by NutraFusion Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 12 active ingredients.
  • “PlantFusion(TM) Amino Acid Infused Protein Blend” is a proprietary blend — the label gives one combined amount (22,000 mg) without saying how much of each component you get.
  • “Providing 4,500 mg BCAAs” is listed as a grouped ingredient — the label gives one combined amount (4,500 mg) without saying how much of each component you get.
  • “PlantFusion(TM) Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.

PlantFusion Unflavored is a plant-based protein powder with 12 active ingredients. The core is an amino acid blend built on L-glutamine, plus the branched-chain amino acids (BCAAs) L-leucine, L-isoleucine, and L-valine — these are the building blocks your muscles need during recovery and growth.

You also get pea protein isolate as the primary protein source. The formula includes mineral and nutrient content from sodium and potassium, bromelain (a protein-digesting enzyme from pineapple), artichoke protein, and two sprouted whole-grain powders: amaranth and quinoa.

It also contains an enzyme blend that aids digestion. The inactive ingredients are fructose, glycine, silica, and stevia — standard fillers and sweeteners.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle strength and energy from plant protein.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Muscle strength, Postoperative recovery, muscle recovery — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

The evidence for effectiveness varies by ingredient. L-glutamine is rated effective for sickle cell disease and possibly effective for HIV-related muscle wasting, postoperative recovery, and critical illness, though most of that research is in medical settings.

Pea protein, amaranth, and quinoa have insufficient evidence to rate — we don't yet know if they deliver the claimed health benefits at supplement doses. Bromelain and artichoke protein show insufficient evidence for most of their proposed uses as well.

If you're considering this product for muscle support or general nutrition, the science is strongest for glutamine in specific medical conditions; for general fitness or wellness, the evidence isn't established in our data.

The evidence, ingredient by ingredient Sodium Potassium Glutamine Artichoke Pea Protein Amaranth Quinoa Bromelain

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Overall, PlantFusion Unflavored is generally well tolerated. L-glutamine is well tolerated in healthy adults but requires medical supervision if you have kidney or liver disease.

Common side effects from glutamine can include belching, bloating, constipation, diarrhea, nausea, and headache. Bromelain and artichoke may each trigger allergic reactions, especially if you're sensitive to pineapple or plants in the ragweed family; pea protein can cause anaphylaxis in people with legume allergies.

Quinoa has caused anaphylaxis in rare cases. Sodium and potassium at the levels in a single serving are generally fine, but your total intake from food, water, and all supplements matters — excess sodium is linked to high blood pressure and kidney strain, and excess potassium can cause dangerous heart rhythm changes.

For pregnancy, L-glutamine and potassium are rated likely safe, and quinoa as a food is likely safe; however, there isn't enough safety data for bromelain or artichoke supplement forms, so they're best avoided. For breastfeeding, similar caution applies — glutamine, potassium, and quinoa have safer profiles, but bromelain and artichoke lack sufficient data.

Side effects, ingredient by ingredient Sodium Potassium Glutamine Artichoke Pea Protein Amaranth Quinoa Bromelain

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 8 matched ingredients can interact with medications — Artichoke, Potassium, Glutamine, Bromelain, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications; lithium.
  • For scale: 574 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take anticonvulsant medications (for seizures), blood pressure drugs, blood thinners or antiplatelet drugs, diabetes medications, corticosteroids, ACE inhibitors or ARBs, potassium-sparing diuretics, lithium, or any sodium-containing medications. The sodium and potassium content, plus interactions from glutamine, bromelain, and artichoke, can alter how these drugs work or increase the risk of serious side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

PlantFusion Unflavored could work as a plant-based protein option if you have no allergies to its plant sources and no kidney, liver, or electrolyte issues. It's worth considering if you need a concentrated amino acid boost post-workout or during recovery.

But because it contains sodium and potassium, you'll want to check with your doctor or pharmacist before starting, especially if you take blood pressure drugs, diabetes medications, blood thinners, anticonvulsants, or lithium — the interactions can be serious. If you have any history of allergies to legumes, pineapple, or ragweed-family plants, mention that too.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PlantFusion Unflavored, straight from the product label.

Brand NutraFusion Nutritionals
Barcode (UPC) 890985001938
Net contents 1 lb; 454 Gram(s)
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30028
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PlantFusion Unflavored by NutraFusion Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Gram(s)
Maximum serving Sizes:
30 Gram(s)
Servings per container
15
UPC/BARCODE
890985001938
IngredientAmount% DV
Calories120 {Calories}--
Total Carbohydrates3 Gram(s)1%
L-Glutamine3350 mg--
Calories from Fat20 {Calories}--
Total Fat2 Gram(s)3%
Protein22 Gram(s)44%
Saturated Fat0 Gram(s)--
Sodium390 mg16%
Potassium60 mg2%
Cholesterol0 Gram(s)--
L-Leucine0 NP--
L-Isoleucine0 NP--
L-Valine0 NP--
Bromelain0 NP--
Alpha-Galactosidase0 NP--
Artichoke Protein0 NP--
Pea Protein isolate0 NP--
Sugar2 Gram(s)--
organic sprouted Amaranth powder0 NP--
organic sprouted Quinoa powder0 NP--
PlantFusion(TM) Amino Acid Infused Protein Blend22000 mg--
Providing 4,500 mg BCAAs4500 mg--
PlantFusion(TM) Proprietary Enzyme Blend100 mg--

Other ingredients: Fructose, Glycine, Silica, Stevia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

+These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

SP91/28 1 110311

General Statements

The Secret is in the Fusion fu•sion noun, \fyu-zhen\; a merging of diverse elements into a unified whole. four of the world’s most potent plant protein sources, fortified with key amino acids and digestive enzymes to create an uncompromising fusion of taste, potency and digestibility all in one.

- Proprietary Enzyme Blend Supports Maximum Absorption Without Stomach Irritation

- Low Glycemic Load

- 100% Natural & Non-GMO - Mixes Easily

The ORIGINAL

nature's most complete plant protein

EASILY DIGESTIBLE-AMAZING TASTE

NOTE: This product is sold by weight not volume. Settling of the contents may occur during shipping

TYPICAL AMINO ACID PROFILE (Milligrams of Amino Acids Per Serving) Alanine 920 mg Arginine 1,860 mg Aspartic Acid 2,460 mg Cystine 215 mg Glutamic Acid 3,740 mg Glycine 1,090 mg Histidine 535 mg Isoleucine 1,320 mg Leucine 2,160 mg Lysine 1,540 mg Methionine 235 mg Phenylalanine 1,180 mg Proline 960 mg Serine 1,130 mg Threonine 835 mg Tryptophan 215 mg Tyrosine 810 mg Valine 1,430 mg

MADE IN THE USA

LIGHTLY SWEETENED

Formula

- Complete Protein Made Only From Plant Sources - New Organic Ingredients - Sprouted Amaranth & Quinoa - Infused BCAAs And L-Glutamine To Support Muscle Strength & Energy - 22g Of Concentrated Protein In One 30g Scoop

HYPOALLERGENIC

Formulation

- Lactose Free and Gentle On The Stomach

- Cholesterol Free

NO DAIRY-NO SOY- NO ANIMAL

GLUTEN FREE

Brand IP Statement(s)

PlantFusion(TM) is Eco-Friendly. Our protein sources do not negatively impact the soil, environment or our community. Manufactured in a cGMP facility.

Seals/Symbols

vegan approved

INFUSED WITH BRANCHED CHAIN AMINO ACIDS & L-GLUTAMINE

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

DIRECTIONS: Add one scoop to either 10 or 12 oz of chilled water in a shaker cup or blender and mix for about 5 seconds. Use once daily as a supplemental source of plant protein.

Storage

Keep tightly closed; store in a cool, dry place away from light, heat and moisture.

Precautions

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PlantFusion Unflavored by NutraFusion Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PlantFusion Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PlantFusion Unflavored by NutraFusion Nutritionals

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size30 Gram(s) Dosage formPowder Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

22 Gram(s) per serving

Sodium

Interacts with
205 drugs
390 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
60 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Sugar

2 Gram(s) per serving Form: Fructose

PlantFusion(TM) Amino Acid Infused Protein Blend

22000 mg per serving

PlantFusion(TM) Proprietary Enzyme Blend

100 mg per serving

Other (inactive) ingredients: Fructose, Glycine, Silica, Stevia. These complete the product’s ingredient list but are not active constituents.

Interaction report

PlantFusion Unflavored by NutraFusion Nutritionals Drug Interactions

Want to check YOUR meds against PlantFusion Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
574Drugs
555 Moderate 19 Minor

Ingredients driving the most interactions

Artichoke Protein 363
Sodium 205
Bromelain 141
Potassium 62
L-Glutamine 50

Individual Drug Interactions

The ingredients in PlantFusion Unflavored interact with 574 drugs. Click any drug to see the details.

5 of the 12 ingredients in PlantFusion Unflavored interact with drugs. Each result below shows which ingredient is responsible. Artichoke Protein Sodium Bromelain Potassium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in PlantFusion Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Artichoke Protein4 drug types · 363 drugs

Antidiabetes Drugs

Theoretically, artichoke leaf extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
A meta-analysis of small clinical studies shows that taking artichoke leaf extract for 8-12 weeks can modestly reduce fasting plasma glucose when compared with placebo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, artichoke leaf extract may increase the risk of hypotension when taken with antihypertensive drugs.
A meta-analysis of small clinical studies in patients with hypertension shows that taking artichoke can reduce systolic blood pressure by around 3 mmHg and diastolic blood pressure by around 2 mmHg when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2B6.
In vitro research shows that artichoke leaf extract inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2C19.
In vitro research shows that artichoke leaf extract inhibits CYP2C19 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Artichoke Protein full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Bromelain2 drug types · 141 drugs

Anticoagulant/Antiplatelet Drugs

Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.

Likelihood Possible Evidence B
Bromelain full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PlantFusion Unflavored, from the product label.

NutraFusion Nutritionals

See all NutraFusion Nutritionals products
Name
NutraFusion NUTRITIONALS
Street Address
3775 Park Ave., Unit #1
City
Edison
State
New Jersey
ZipCode
08820
Phone Number
800.519.6266
Web Address
www.plantfusion.net
Pharmacist Counseling Corner

PlantFusion Unflavored by NutraFusion Nutritionals: Common Questions

Does PlantFusion Unflavored by NutraFusion Nutritionals interact with any medications?
Yes. Based on its ingredients, PlantFusion Unflavored has a known interaction with 574 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PlantFusion Unflavored contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the branched-chain amino acids (BCAAs) in this, and why are they in here?
This powder contains L-leucine, L-isoleucine, and L-valine — three of the nine amino acids your body can't make on its own. They're included because they're thought to support muscle recovery after exercise, though we don't have strong evidence for effectiveness at supplement doses.
Can I take this if I'm pregnant or breastfeeding?
Some ingredients are likely safe — glutamine, potassium, and quinoa have OK pregnancy/breastfeeding data — but bromelain and artichoke protein don't have enough safety information in pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether this formula is right for you at this time.
What's bromelain, and why is it in a protein powder?
Bromelain is an enzyme from pineapple that breaks down proteins. It's added to help your digestive system absorb the protein and amino acids in the formula, though side effects from it may include diarrhea or stomach upset.
Is this safe if I'm allergic to tree nuts or peanuts?
This product is nut-free, but pea protein can cause anaphylaxis in people with pea or legume allergies, and bromelain comes from pineapple. If you have a known allergy to peas, legumes, pineapple, or plants in the ragweed family (like artichoke), avoid this product.
How much sodium and potassium does one serving have, and is it a problem?
The product facts don't specify the per-serving amounts, so check the nutrition label. If you have high blood pressure, heart disease, or kidney problems, or if you take blood pressure or heart medications, talk with your pharmacist about whether this level is okay for you.
Can I use this for muscle building, or is it only for medical conditions?
While glutamine is effective for sickle cell disease and possibly helpful after surgery or during critical illness, we don't have strong evidence that this powder works for general fitness or muscle building. It's a protein source, so it does provide amino acids your muscles need — but whether the specific formula and dose deliver extra benefit for healthy people isn't established in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PlantFusion Unflavored label
Go deeper

The Full Monographs Behind PlantFusion Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Artichoke

Interacts with 363 drugs

Artichoke leaf extract is a generally well-tolerated supplement that may have a mild cholesterol-lowering effect and is often used for indigestion, though the evidence is modest. It is not a...

Read the full Artichoke monograph → Herb & supplement monograph

Pea Protein

Pea protein is a plant-based protein powder made from yellow split peas, commonly used by people who want a dairy-free or vegan source of protein to support muscle and overall protein intake...

Read the full Pea Protein monograph → Herb & supplement monograph

Amaranth

Amaranth is a nutritious plant whose seeds are used as a gluten-free pseudocereal and whose leaves are eaten as a vegetable. It is generally considered safe as a food, but evidence for its m...

Read the full Amaranth monograph → Herb & supplement monograph

Quinoa

Quinoa is a nutritious, gluten-free seed eaten like a grain, rich in protein, fiber, and minerals. It is best thought of as a healthy food rather than a medicine, and most people can enjoy i...

Read the full Quinoa monograph → Herb & supplement monograph

Bromelain

Interacts with 141 drugs

Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early studies are promising, but the overall evi...

Read the full Bromelain monograph →
Sources

Sources & How We Checked

PlantFusion Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 108 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
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Sodium 38 references
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Potassium 12 references
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See these in context on the Potassium monograph →

Bromelain 19 references
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See these in context on the Bromelain monograph →

Artichoke 16 references
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  6. Franck, P., Moneret-Vautrin, D. A., Morisset, M., Kanny, G., Megret-Gabeaux, M. L., and Olivier, J. L. Anaphylactic reaction to inulin: first identification of specific IgEs to an inulin protein compound. Int Arch Allergy Immunol 2005;136(2):155-158. PubMed
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Pea Protein 1 reference
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See these in context on the Pea Protein monograph →

Amaranth 6 references
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  2. Martirosyan, D. M., Miroshnichenko, L. A., Kulakova, S. N., Pogojeva, A. V., and Zoloedov, V. I. Amaranth oil application for coronary heart disease and hypertension. Lipids Health Dis. 2007;6:1.
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Quinoa 5 references
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  3. De Carvalho FG, Ovídio PP, Padovan GJ, Jordão Junior AA, Marchini JS, Navarro AM. Metabolic parameters of postmenopausal women after quinoa or corn flakes intake--a prospective and double-blind study. Int J Food Sci Nutr. 2014;65(3):380-5. PubMed
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See these in context on the Quinoa monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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