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Dietary supplement

PMS Sweets Sweet Peppermint Ingredients & Drug Interactions

by Pink Stork

Lozenge Category: Vitamin
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

PMS Sweets Sweet Peppermint is a dietary supplement by Pink Stork with 1 active ingredient. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 210 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pyridoxine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of PMS Sweets Sweet Peppermint by Pink Stork

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This lozenge contains one active ingredient: pyridoxine hydrochloride, a form of vitamin B6. The inactive ingredients are cane sugar, organic brown rice syrup, and organic peppermint oil for flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eases menstrual discomfort.
  • We looked for evidence on: Dysmenorrhea, Premenstrual syndrome (PMS), menstrual pain, period cramps.
  • The strongest evidence on file: Vitamin B6 is rated "Possibly Effective" for Premenstrual syndrome (PMS) (Natural Medicines).
  • Also on file: Vitamin B6 is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea.

Vitamin B6 is effective for treating sideroblastic anemia and vitamin B6 deficiency, and it's effective for pyridoxine-dependent epilepsy. It's likely effective for high homocysteine levels (hyperhomocysteinemia).

For pregnancy-related nausea and vomiting, the evidence is weaker — the rating is possibly effective — and it's used at recommended levels only under a doctor's guidance.

The evidence, ingredient by ingredient Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is well tolerated in doses under 100 mg daily. Common side effects at normal doses are uncommon but can include headache, nausea, heartburn, and stomach pain.

The real concern is high doses taken over time: they can cause nerve damage (sensory neuropathy), especially above 1,000 mg daily or with cumulative doses of 1,000 grams or more, though nerve damage can occur at lower doses too. During pregnancy, B6 is likely safe, but there's also a possibly unsafe rating for it in pregnancy — talk with your doctor about whether this product is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin B6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: Parkinson's medications.
  • For scale: 210 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood pressure medications, the heart drug amiodarone (Cordarone), seizure medications like phenobarbital (Luminal) or phenytoin (Dilantin), or Parkinson's medication levodopa. Vitamin B6 can interact with all of these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help if you have vitamin B6 deficiency or certain types of anemia. If you take blood pressure medication, heart rhythm drugs, or seizure medications, check with your doctor or pharmacist before starting — vitamin B6 can affect how well they work or make their side effects worse.

Talk it over with your own healthcare provider if you're pregnant, nursing, or taking any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PMS Sweets Sweet Peppermint, straight from the product label.

Brand Pink Stork
Barcode (UPC) 851204007704
Net contents 30 Piece(s); 4 Ounce(s); 120 Gram(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 216909
Product type Vitamin
Supplement form Lozenge
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Organic, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PMS Sweets Sweet Peppermint by Pink Stork, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Piece(s)
Maximum serving Sizes:
6 Piece(s)
Servings per container
30
UPC/BARCODE
851204007704
IngredientAmount% DV
Calories50 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Added Sugars3 Gram(s)6%
Total Sugars3 Gram(s)--
Pyridoxine Hydrochloride15 mg882%

Other ingredients: Cane Sugar, organic Brown Rice syrup, organic Peppermint Oil, Vitamin B6

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Organic drop/lozenge + B6

Pink Stork PMS Sweets are natural, tasty treats packed with organic peppermint and Vitamin B6.

Formulation

Eases menstrual discomfort

Gluten-free Preservative-free

USDA Organic

Peppermint has been used for millennia to soothe cramps and bloat and it supports mental clarity and energy levels. Vitamin B6 is an effective and proven helper for PMS symptoms and is widely recommended - when you put the two together, it's the perfect pair. Cool and refreshing, this peppermint sweet is a delicious and helpful treat.

Certified Organic by QAI

Contains no: GMOs, gluten, wheat, sweeteners, colors, animal products, shellfish, preservatives, fish, soy, tree nuts, peanuts, dairy.

Seals/Symbols

USDA Organic

Quality Assurance International Certified Organic

General Statements

Women Owned

XOXO Amy Founder & CEO

Amy's Mission Pink Stork founder, mother of 5, and military spouse, Amy Upchurch is committed to helping others experience the power of natural and organic products products that saved and changed her life during her 4th and 5th pregnancies.

Find us on @pinkstork Share your story: #pinkstork Free guides @ pinkstork.com/download

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Best use: Take 1-6 pieces daily as needed.

See for yourself

PMS Sweets Sweet Peppermint by Pink Stork label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PMS Sweets Sweet Peppermint by Pink Stork

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Piece(s) Dosage formLozenge Servings per container30 Amounts shown are per serving.

Pyridoxine Hydrochloride

Interacts with
210 drugs
15 mg per serving Form: Vitamin B6

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Pyridoxine Hydrochloride monograph & interactions

Other (inactive) ingredients: Cane Sugar, Organic Brown Rice syrup, Organic Peppermint Oil, Vitamin B6. These complete the product’s ingredient list but are not active constituents.

Interaction report

PMS Sweets Sweet Peppermint by Pink Stork Drug Interactions

Want to check YOUR meds against PMS Sweets Sweet Peppermint?

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Go to the checker
210Drugs
205 Moderate 5 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in PMS Sweets Sweet Peppermint with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pyridoxine Hydrochloride5 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for PMS Sweets Sweet Peppermint, from the product label.

Pink Stork

See all Pink Stork products
Name
Augustine, Inc.
Street Address
1093 A1A Beach Blvd., Suite 334
City
St. Augustine Beach
State
Florida
ZipCode
32080
Phone Number
877.262.9684
Web Address
www.pinkstork.com
Pharmacist Counseling Corner

PMS Sweets Sweet Peppermint by Pink Stork: Common Questions

Does PMS Sweets Sweet Peppermint by Pink Stork interact with any medications?
Yes. Based on its ingredients, PMS Sweets Sweet Peppermint has a known interaction with 210 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PMS Sweets Sweet Peppermint contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with PMS symptoms?
The product is named for PMS, but the only ingredient here is vitamin B6. The data we hold shows B6 is effective for B6 deficiency and certain types of anemia, and possibly effective for pregnancy-related nausea and vomiting. There's no evidence in our facts about its use for PMS symptoms — that's a question for your doctor.
Is vitamin B6 safe to take every day?
Vitamin B6 is well tolerated at doses under 100 mg daily. The concern is with high doses over time — they can damage nerves, especially above 1,000 mg daily. At normal dietary and recommended amounts, it's generally considered fine, but avoid high doses unless a clinician advises it.
Can I take this if I'm pregnant?
Vitamin B6 has mixed safety data for pregnancy: it's rated likely safe, but also possibly unsafe. There's not enough clarity in the data we hold to say yes or no. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.
What are the side effects?
At normal doses, vitamin B6 is well tolerated and serious side effects are rare. The most common minor effects are headache, nausea, heartburn, and stomach pain. High doses over time can cause nerve damage (numbness and tingling), especially at very high intakes.
Can I take this while breastfeeding?
Vitamin B6 is rated likely safe during lactation. That said, if you're nursing and have questions about whether this specific product is right for you, check with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PMS Sweets Sweet Peppermint is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PMS Sweets Sweet Peppermint label
Go deeper

The Full Monographs Behind PMS Sweets Sweet Peppermint’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

PMS Sweets Sweet Peppermint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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