Powder Multidophilus Unflavored Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Powder Multidophilus Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Powder Multidophilus Unflavored is a dietary supplement by Solaray with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L. acidophilus, B. bifidum, L. bulgaricus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Powder Multidophilus Unflavored by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Powder Multidophilus Unflavored by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Powder Multidophilus Unflavored by Solaray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This powder contains three active probiotic ingredients: Lactobacillus acidophilus, Bifidobacterium bifidum, and Lactobacillus bulgaricus. These are live beneficial bacteria intended to support gut and digestive health.
The product also includes inactive ingredients—maltodextrin and silica—which serve as carriers and anti-caking agents.
Does it work?
Moderate evidence
The evidence for these strains is mixed. L. acidophilus and B. bifidum are both possibly effective for irritable bowel syndrome (IBS) and possibly effective for antibiotic-associated diarrhea.
L. acidophilus is also possibly effective for Helicobacter pylori infection and bacterial vaginosis. For many other conditions—including allergies, respiratory infections, anxiety, and cold prevention—the evidence we hold is insufficient to rate whether these strains help.
L. bulgaricus has insufficient evidence for most conditions listed. Talk with your doctor about what this product might do for your specific situation.
How safe is it?
Well-documented data
The three strains are generally well tolerated in healthy adults and children. That said, they contain live organisms, so there is a theoretical risk of infection in people with weakened immune systems; if that's you, check with your doctor first.
Uncommon side effects from the probiotics themselves include bloating, flatulence, abdominal discomfort, and diarrhea. Rarely, serious infections (bacteremia, sepsis, abscess) have been reported, though these are thought to occur mainly when bacteria escape from their normal locations in the body—a risk that's highest in critically ill or immunocompromised patients.
Pregnancy and breastfeeding safety data aren't on file for these strains; talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your pharmacist before taking this with antibiotic drugs—they can kill the live bacteria in the powder and reduce its effectiveness. Separate your antibiotic and probiotic doses by a few hours.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with IBS or antibiotic-associated diarrhea if the evidence pans out for you. The key thing to know: if you're on antibiotics, space out your doses.
If you have a weakened immune system or are very ill, ask your pharmacist before starting. Run your medications through the checker below.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Powder Multidophilus Unflavored, straight from the product label.
| Brand | Solaray |
|---|---|
| Barcode (UPC) | 076280048339 |
| Net contents | 2.5 Ounce(s); 71 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2020 |
| DSLD ID | 239861 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Powder Multidophilus Unflavored by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L. acidophilus | 0 NP | -- |
| B. bifidum | 0 NP | -- |
| L. bulgaricus | 0 NP | -- |
| Triple Strain Probiotic Blend | 530 mg | -- |
Other ingredients: Maltodextrin, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Formula
3 triple strain formula 5 billion CFU
Discussion: L. bulgaricus is intended to help the GI tract be more suitable for the survival and growth of L. acidophilus and B. bifidum. L. acidophilus is the primary bacteria of the small intestine while B. bifidum is the major bacteria of the large intestine. The strains of L. acidophilus and B. bifidum used in this product have been the subject of invitro tests to help ensure they are more likely to be implantable, attaching themselves to the intestinal wall and becoming part of the naturally occurring flora.
Formulation
Dairy free
Freeze dried
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Mix 1/8 heaping teaspoon of powder into water, juice or food. Do not take within two hours of taking antibiotics.
Storage
Keep refrigerated.
General Statements
Some settling of contents may occur during shipping.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Powder Multidophilus Unflavored by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Powder Multidophilus Unflavored by Solaray
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.54 Gram(s) Dosage formPowder Servings per container130 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Triple Strain Probiotic Blend
Other (inactive) ingredients: Maltodextrin, Silica. These complete the product’s ingredient list but are not active constituents.
Powder Multidophilus Unflavored by Solaray Drug Interactions
HelloPharmacist Interaction Report
Solaray Powder Multidophilus Unflavored contains three live probiotic strains, and all three interact with antibiotic drugs.
When you take antibiotics at the same time as this product, the antibiotics can kill the live organisms in the powder, which may reduce how well the probiotics work. The interaction is Moderate severity for all three strains.
Read the full breakdown — every affected drug type, severity by severity
To manage this, separate your doses: take your antibiotic and this probiotic at least a few hours apart. Your pharmacist or doctor can help you space them properly based on your antibiotic schedule.
Additionally, we could not check a few ingredients that may be part of the blend; however, the three named strains account for the interactions we have documented. Use the medication checker on this page to verify your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Powder Multidophilus Unflavored?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Powder Multidophilus Unflavored interact with 182 drugs. Click any drug to see the details.
3 of the 3 ingredients in Powder Multidophilus Unflavored interact with drugs. Each result below shows which ingredient is responsible. L. acidophilus B. bifidum L. bulgaricus
Lefamulin AcetateXenleta
How Lefamulin Acetate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Lefamulin Acetate interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Lefamulin Acetate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Lefamulin Acetate interactionLevofloxacinLeva-pak, Levaquin, Levaquin Injection
How Levofloxacin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Levofloxacin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Levofloxacin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Levofloxacin interactionLevofloxacin (ophthalmic)Levofloxacin
How Levofloxacin (ophthalmic) interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Levofloxacin (ophthalmic) interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Levofloxacin (ophthalmic) interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Levofloxacin (ophthalmic) interactionLincomycin HclLincocin, Lincorex
How Lincomycin Hcl interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Lincomycin Hcl interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Lincomycin Hcl interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Lincomycin Hcl interactionLinezolidZyvox, Zyvox Injection
How Linezolid interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Linezolid interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Linezolid interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Linezolid interactionLomefloxacinMaxaquin
How Lomefloxacin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Lomefloxacin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Lomefloxacin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Lomefloxacin interactionLoracarbefLorabid
How Loracarbef interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Loracarbef interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Loracarbef interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Loracarbef interactionMeropenemMerrem IV
How Meropenem interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Meropenem interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Meropenem interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Meropenem interactionMeropenem, VaborbactamVabomere
How Meropenem, Vaborbactam interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Meropenem, Vaborbactam interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Meropenem, Vaborbactam interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Meropenem, Vaborbactam interactionMethacyclineRondomycin
How Methacycline interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methacycline interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methacycline interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methacycline interactionMethenamine HippurateHiprex, Urex
How Methenamine Hippurate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine Hippurate interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine Hippurate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine Hippurate interactionMethenamine MandelateMandelamine, Methimazole
How Methenamine Mandelate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine Mandelate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine Mandelate interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine Mandelate interactionMethenamine Mandelate, Potassium Acid PhosphateThiacide
How Methenamine Mandelate, Potassium Acid Phosphate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine Mandelate, Potassium Acid Phosphate interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine Mandelate, Potassium Acid Phosphate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine Mandelate, Potassium Acid Phosphate interactionMethenamine Mandelate, Sodium Acid PhosphateUroquid-Acid No. 2
How Methenamine Mandelate, Sodium Acid Phosphate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine Mandelate, Sodium Acid Phosphate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine Mandelate, Sodium Acid Phosphate interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine Mandelate, Sodium Acid Phosphate interactionMethenamine, Phenyl Salicylate, Methylene BlueProsed DS
How Methenamine, Phenyl Salicylate, Methylene Blue interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine, Phenyl Salicylate, Methylene Blue interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine, Phenyl Salicylate, Methylene Blue interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine, Phenyl Salicylate, Methylene Blue interactionMethenamine, Sodium BiphosphateUro-Phosphate
How Methenamine, Sodium Biphosphate interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Methenamine, Sodium Biphosphate interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Methenamine, Sodium Biphosphate interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Methenamine, Sodium Biphosphate interactionMetronidazoleAnabact, Flagyl, Flagyl IV, Flagyl IV RTU, Likmez, Metro IV +12 more
How Metronidazole interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Metronidazole interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Metronidazole interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Metronidazole interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMezlocillinMezlin
How Mezlocillin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Mezlocillin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Mezlocillin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Mezlocillin interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Minocycline interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Minocycline interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Minocycline Hydrochloride interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Minocycline Hydrochloride interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Minocycline Hydrochloride interactionMoxifloxacinAvelox
How Moxifloxacin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Moxifloxacin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Moxifloxacin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Moxifloxacin interactionNafcillinNallpen
How Nafcillin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Nafcillin interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Nafcillin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Nafcillin interactionNafcillin SodiumUnipen
How Nafcillin Sodium interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Nafcillin Sodium interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Nafcillin Sodium interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Nafcillin Sodium interactionNalidixic AcidNegGram
How Nalidixic Acid interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Nalidixic Acid interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Nalidixic Acid interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Nalidixic Acid interactionNeomycinMycifradin, Myciguent, Neo-Fradin
How Neomycin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Neomycin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Neomycin interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Neomycin interactionNetilmicinNetromycin
How Netilmicin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Netilmicin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Netilmicin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Netilmicin interactionNitrofurantoinFuradantin, Furatoin, Macrobid, Macrodantin
How Nitrofurantoin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Nitrofurantoin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Nitrofurantoin interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Nitrofurantoin interactionNorfloxacinNorflox, Noroxin
How Norfloxacin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
L. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Norfloxacin interactionB. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Norfloxacin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Norfloxacin interactionOfloxacinFloxin, Floxin Injection, Floxin Otic, Oflox
How Ofloxacin interacts with Powder Multidophilus Unflavored — through 3 ingredients. Tap an ingredient for the detail:
B. BifidumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium.
Read the full B. Bifidum + Ofloxacin interactionL. BulgaricusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Bulgaricus + Ofloxacin interactionL. AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full L. Acidophilus + Ofloxacin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Powder Multidophilus Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
L. acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
B. bifidum
Antibiotic Drugs
Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.
L. bulgaricus
Antibiotic Drugs
Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.
Brand information
Manufacturer and brand details for Powder Multidophilus Unflavored, from the product label.
Powder Multidophilus Unflavored by Solaray: Common Questions
Does Powder Multidophilus Unflavored by Solaray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this with antibiotics?
Does this help with IBS or diarrhea?
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What are L. acidophilus, B. bifidum, and L. bulgaricus?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Powder Multidophilus Unflavored is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Powder Multidophilus Unflavored’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Bifidum
Interacts with 182 drugsBifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...
Read the full Bifidobacterium Bifidum monograph → Herb & supplement monographLactobacillus Delbrueckii
Interacts with 182 drugsLactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...
Read the full Lactobacillus Delbrueckii monograph →Sources & How We Checked
Powder Multidophilus Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Bifidobacterium Bifidum 7 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
See these in context on the Bifidobacterium Bifidum monograph →
Lactobacillus Delbrueckii 9 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
- Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
- Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
- Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
- Neonakis IK, Skamagkas I, Stafylaki D, Maraki S. Lactobacillus delbrueckii urinary tract infection in a male patient: a case report. Germs 2022;12(2):304-307. PubMed
- Maillet F, Passeron A, Podglajen I, Ranque B, Pouchot J. Lactobacillus delbrueckii urinary tract infection in a male patient. Med Mal Infect 2019;49(3):226-228. PubMed
- Darbro BW, Petroelje BK, Doern GV. Lactobacillus delbrueckii as the cause of urinary tract infection. J Clin Microbiol 2009;47(1):275-7.
See these in context on the Lactobacillus Delbrueckii monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC