Major interaction on record — check this product against your medications before combining. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

PR-XT Ingredients & Drug Interactions

by MAN Sports Nutrition

PR-XT label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PR-XT against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

PR-XT is a dietary supplement by MAN Sports Nutrition with 3 active ingredients. Its ingredients are commonly taken for toothache and oral discomfort, increasing saliva flow, sluggish digestion.Based on those ingredients, 1,356 medications have a known interaction with it, the most serious rated major. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PR-XT by MAN Sports Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with PR-XT by MAN Sports Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of PR-XT by MAN Sports Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 9 active ingredients.
  • “S7” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.
  • “PR-XT Caps Blend” is a proprietary blend — the label gives one combined amount (2,400 mg) without saying how much of each component you get.

PR-XT contains 9 active ingredients: green tea extract, kale, broccoli, blueberry, tart cherry, turmeric extract, green coffee bean extract, S7 (a blend), and anacyclus pyrethrum DC root extract, plus MitoBurn. The inactive ingredients are gelatin, titanium dioxide, colorants (FD&C Blue #1, Red #3, Yellow #6, Red #40), rice flour, and vegetable stearate.

The product appears designed as a performance and wellness blend combining plant extracts rich in polyphenols, caffeine (from green tea and green coffee bean), and cruciferous vegetables with traditional herbal ingredients. The exact roles and doses of S7 and MitoBurn are not detailed in the available data.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery and athletic performance enhancement.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, muscle protein synthesis, post-exercise recovery, ergogenic effect.
  • The strongest evidence on file: Sour Cherry is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Turmeric is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle soreness, Exercise-induced muscle damage.
  • Also on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness.

Evidence for PR-XT's active ingredients is mixed. Green tea extract is likely effective for HPV-related conditions and possibly effective for high cholesterol and ovarian cancer.

Broccoli is possibly effective for colorectal cancer. Blueberry, tart cherry, and kale lack sufficient reliable evidence for the conditions tested in our data.

Turmeric extract is possibly effective for depression, high cholesterol, hay fever, and indigestion. Green coffee bean extract is likely effective for mental alertness and possibly effective for Parkinson disease, heart failure, and diabetes.

No effectiveness data are held for anacyclus pyrethrum, S7, PR-XT Caps Blend, or MitoBurn. The overall effectiveness of this combination product for its intended use is not established in the data we hold.

The evidence, ingredient by ingredient Pellitory

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Green tea extract in moderate amounts is generally well tolerated, though high-dose concentrated extracts carry a rare risk of liver injury. Most common side effects are mild gastrointestinal ones (nausea, bloating, constipation, diarrhea).

Rare serious effects include liver damage, low potassium, and a blood clotting disorder. Green tea proteins have triggered anaphylaxis in at least one documented case, and caffeine-related anaphylaxis, though rare, is possible in sensitive individuals.

Broccoli as food is safe, though broccoli extracts at high doses may cause loose stools and abdominal pain. Blueberry is generally well tolerated; freeze-dried forms may cause constipation, diarrhea, nausea, or vomiting in some users.

Turmeric is well tolerated at food amounts but can cause constipation, heartburn, diarrhea, nausea, and vomiting at supplement doses; it has been linked to liver damage in at least 70 reports, most reversing after stopping. Green coffee bean extract can cause agitation, anxiety, insomnia, headache, and jitteriness at higher caffeine doses.

Kale and tart cherry are generally well tolerated. Anacyclus pyrethrum may cause mouth or skin irritation and allergic reactions.

MitoBurn's safety profile is not available. Limited safety data exist for pregnancy and lactation across most ingredients; discuss with your doctor or pharmacist before use if you are pregnant or breastfeeding.

Side effects, ingredient by ingredient Pellitory

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 8 matched ingredients can interact with medications — Turmeric, Green Tea, Coffee, Blueberry, Broccoli.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications; lithium.
  • For scale: 1,357 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking PR-XT, double-check with your doctor or pharmacist if you take ephedrine or any stimulants (Major risk). Also confirm if you're on beta-blockers like nadolol, cholesterol medications like atorvastatin, seizure drugs, blood thinners, cancer medications (especially tamoxifen or chemotherapy agents), the immunosuppressant tacrolimus, lamotrigine (Lamictal), clozapine (Clozaril), or diabetes medications.

These represent the most serious interaction categories documented for the ingredients we could verify.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

PR-XT is a multi-ingredient supplement combining plant extracts and herbal ingredients, some with established effectiveness for specific conditions and others lacking sufficient evidence. The product carries significant drug interaction risks, especially if you take ephedrine, blood pressure medications, cholesterol drugs, seizure medications, anticoagulants, or cancer therapies.

Anyone on prescription medications should check their specific drugs against the interaction tool on this page and discuss the results with their own doctor or pharmacist before starting PR-XT.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PR-XT, straight from the product label.

Brand MAN Sports Nutrition
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 274849
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PR-XT by MAN Sports Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
IngredientAmount% DV
Green Tea extract0 NP--
Kale0 NP--
Broccoli0 NP--
Blueberry0 NP--
Tart Cherry0 NP--
Turmeric extract0 NP--
Green Coffee bean extract0 NP--
S7100 mg--
PR-XT Caps Blend2400 mg--
Anacyclus pyrethrum DC Root Extract1800 mg--
MitoBurn500 mg--

Other ingredients: Gelatin, Titanium Dioxide, FD&C Blue#1, Red #3, Yellow #6, Red #40, Rice Flour, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

4 week cycle

Formulation

Potent recomposition & ergogenic aid

Formula

Anabolic, lipolysis & peak nitric oxide (For advanced users only) AP-DC (1,800mg) Anacyclus Pyethrum DC

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Mitoburn is a trademark of NNB Nutrition S7 is a trademark of VDF FutureCeuticals, Inc., used under license

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PR-XT by MAN Sports Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PR-XT label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PR-XT by MAN Sports Nutrition

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

PR-XT Caps Blend

2400 mg per serving

Other (inactive) ingredients: Gelatin, Titanium Dioxide, FD&C Blue#1, Red #3, Yellow #6, Red #40, Rice Flour, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

PR-XT by MAN Sports Nutrition Drug Interactions

Want to check YOUR meds against PR-XT?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,356Drugs
13 Major 1,320 Moderate 23 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in PR-XT interact with 1,356 drugs. Click any drug to see the details.

0 of the 3 ingredients in PR-XT interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in PR-XT with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for PR-XT, from the product label.

MAN Sports Nutrition

See all MAN Sports Nutrition products
Name
MAN Sports Nutrition
Pharmacist Counseling Corner

PR-XT by MAN Sports Nutrition: Common Questions

Does PR-XT by MAN Sports Nutrition interact with any medications?
Yes. Based on its ingredients, PR-XT has a known interaction with 1,356 medications, including 13 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PR-XT contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does PR-XT work for (my specific goal)?
That depends on what you're using it for. Green tea is likely effective for HPV and possibly for cholesterol and ovarian cancer. Turmeric is possibly effective for depression, cholesterol, hay fever, and digestion. Green coffee bean is likely effective for alertness and possibly for Parkinson disease, heart failure, and diabetes. For other conditions, evidence in our data is insufficient or not established for this product as a whole.
Can I take PR-XT if I'm pregnant or breastfeeding?
The safety data for these ingredients during pregnancy and lactation are incomplete or mixed. Green tea's caffeine content, for example, is not ideal in pregnancy or while breastfeeding. Kale and blueberry are considered likely safe as foods, but concentrated supplement forms lack solid safety data. Talk to your doctor or pharmacist before using PR-XT if you're pregnant or nursing.
What side effects might I experience from PR-XT?
The most common side effects come from green tea and broccoli—mild gastrointestinal complaints like nausea, bloating, constipation, or diarrhea. Caffeine from green tea and green coffee bean can trigger jitteriness, anxiety, headache, or insomnia, especially at higher doses. Turmeric may cause heartburn or constipation. Serious side effects are rare but can include liver injury from concentrated green tea or turmeric extracts.
Is PR-XT safe to use long-term?
Green tea extract appears well tolerated for up to 12 months in studies, though high-dose concentrated forms carry a rare liver-injury risk. Long-term safety data for the full combination—especially MitoBurn and S7—are not detailed in the available information. Talk to your doctor or pharmacist about whether long-term use is right for you.
What is S7 or MitoBurn in this product?
S7 is listed as a blend of component ingredients shown separately in the label. MitoBurn's interaction and safety data are not held in our system, so we cannot provide details about it.
Does PR-XT contain any fillers or unnecessary ingredients?
The product includes inactive ingredients (gelatin, titanium dioxide, rice flour, vegetable stearate, and food colorants) that serve as capsule material and binders. These are standard in capsule supplements and allow the formula to be manufactured and stored properly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PR-XT is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PR-XT label
Go deeper

The Full Monographs Behind PR-XT’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pellitory

Pellitory (often Anacyclus pyrethrum, the root traditionally called 'pellitory of Spain') is an herb chiefly known in folk and traditional medicine for numbing toothache and stimulating sali...

Read the full Pellitory monograph →
Sources

Sources & How We Checked

PR-XT's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 515 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Green Tea 219 references
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  46. Ahn WS, Yoo J, Huh SW, et al. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions. Eur J Cancer Prev 2003;12:383-90. PubMed
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See these in context on the Turmeric monograph →

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Pellitory 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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