Max Potency Probiotic Pearls 5 Billion Ingredients & Drug Interactions
by Nature's Way
What is this page for?
First and foremost: checking Max Potency Probiotic Pearls 5 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Max Potency Probiotic Pearls 5 Billion is a dietary supplement by Nature's Way with 4 active ingredients. Its ingredients are commonly taken for digestive health and regularity, irritable bowel syndrome (ibs), diarrhea (including antibiotic-related).Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium longum BB536, Howaru. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Max Potency Probiotic Pearls 5 Billion by Nature's Way
Ask about any prescription or over-the-counter medication and we check it for interactions with Max Potency Probiotic Pearls 5 Billion by Nature's Way — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Max Potency Probiotic Pearls 5 Billion by Nature's Way
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Max Potency Probiotic Pearls 5 Billion contains four active probiotic ingredients—live beneficial bacteria meant to support digestive health. The product includes Bifidobacterium longum BB536 and Lactobacillus acidophilus (sold under the brand name Howaru), plus Bifidobacterium animalis lactis BL-04 and Lactobacillus plantarum LP-115.
These strains come in a proprietary blend formulation. The softgel capsule also contains inactive ingredients—palm oil, gelatin, glycerin, sunflower lecithin, pectin, and soy lecithin—that serve as the capsule shell and help deliver the live organisms.
Does it work?
Moderate evidence
The evidence for this product's ingredients is mixed. Lactobacillus acidophilus (Howaru) shows possibly effective evidence for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
For Bifidobacterium longum, though, we don't have enough reliable evidence to rate whether it works for age-related cognitive decline, allergic rhinitis (hay fever), antibiotic-associated diarrhea, generalized anxiety, asthma, or athletic performance. We hold no effectiveness data for the other two bacterial strains in this product.
How safe is it?
Well-documented data
Bifidobacterium longum is generally well tolerated in healthy people, but caution is needed if you're seriously ill or have a weakened immune system. Rare gastrointestinal side effects include abdominal discomfort, pain, bloating, flatulence, constipation, and in one case a dry cough.
In critically ill infants and adults—especially those with heart defects or recent surgery—there have been rare cases of the bacteria entering the bloodstream and causing serious infection. Lactobacillus acidophilus is generally well tolerated in healthy adults and children.
When combined with other probiotics, it may rarely cause gastrointestinal discomfort, bloating, diarrhea, or vomiting. Like Bifidobacterium longum, it can theoretically cause serious infection if it enters the bloodstream, though this is rare and typically occurs only in severely compromised patients.
Safety data for breastfeeding are limited for Bifidobacterium longum; there's no safety data on file for Lactobacillus acidophilus during breastfeeding.
Meds to double-check
Moderate interaction found
Antibiotic drugs (Moderate severity): the live bacteria in this product may be killed by antibiotics taken at the same time, reducing the probiotic's effectiveness. Separate your doses—ask your pharmacist for a timeline.
Two of the four bacterial strains in this product couldn't be checked against our database, so run your exact medications through the checker on this page to be thorough.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic may help if you have IBS, antibiotic-associated diarrhea, or certain digestive concerns—talk to your pharmacist about whether it's right for your situation. If you take antibiotics, separate them from this product to avoid reducing its effectiveness.
Healthy adults and children generally tolerate it well, but if you're seriously ill, immunocompromised, pregnant, or breastfeeding, check with your doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Max Potency Probiotic Pearls 5 Billion, straight from the product label.
| Brand | Nature's Way |
|---|---|
| Barcode (UPC) | 763948050734 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2025 |
| DSLD ID | 334440 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Max Potency Probiotic Pearls 5 Billion by Nature's Way, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Probiotic Blend | 17 mg | -- |
| Bifidobacterium animalis lactis BL-04 | 0 NP | -- |
| Bifidobacterium longum BB536 | 0 NP | -- |
| Lactobacillus plantarum LP-115 | 0 NP | -- |
| Howaru | 0 NP | -- |
Other ingredients: Palm Oil, Gelatin, Glycerin, Sunflower Lecithin, Pectin, Soy Lecithin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
5 Billion cultures Pearls Easy to swallow 4 probiotic strains
Proprietary probiotic blend provides 5 billion active cultures Formulated with 4 probiotic strains to benefit the small and large intestines
Howaru probiotic quality you can feel
Formulation
Supports digestive, immune & colon health Protects against occasional bloating & constipation Designed to survive stomach acid
Survives stomach acid to release in the intestine Easy to swallow Survives stomach acid
Maximum strength formula Protects against occasional bloating, constipation, and digestive discomfort Advanced triple-layer softgel survives stomach aid
Contains no salt, wheat, or artificial colors.
Product of Japan
FDA Statement of Identity
Probiotic Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
Nature's Way The Smarter Probiotic
HOWARU is a registered trademark of IFF and is used under license. Copyright 2023 Nature's Way Brands, LLC
Suggested/Recommended/Usage/Directions
Once daily
Recommendation: Adults swallow 1 softgel daily. May be taken with or without food.
Storage
No refrigeration required
Store at room temperature. Avoid excessive heat and direct sunlight.
General Statements
Explore more products at naturesway.com Questions? 1-800-9NATURE / pearlsprobiotics.com
Precautions
Contains milk, soy, and fish (tilapia).
Do not chew or crush.
If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.
Keep out of reach of children.
This product has a tamper-evident foil pouch. Do not use if foil or plastic is punctured.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Max Potency Probiotic Pearls 5 Billion by Nature's Way label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Max Potency Probiotic Pearls 5 Billion by Nature's Way
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Probiotic Blend
- › Bifidobacterium animalis lactis BL-04
- › Bifidobacterium longum BB536
- › Lactobacillus plantarum LP-115
- › Howaru
Other (inactive) ingredients: Palm Oil, Gelatin, Glycerin, Sunflower Lecithin, Pectin, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.
Max Potency Probiotic Pearls 5 Billion by Nature's Way Drug Interactions
HelloPharmacist Interaction Report
Max Potency Probiotic Pearls 5 Billion by Nature's Way contains live bacterial strains, and two of them do interact with medications.
The most serious concern is with antibiotic drugs (Moderate severity): both Bifidobacterium longum and Lactobacillus acidophilus—the live organisms in this product—may be killed off if you take antibiotics at the same time, which would reduce how well the probiotic works. The data advises separating when you take antibiotics and this product.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we could not check two of the four ingredients (Bifidobacterium animalis lactis BL-04 and Lactobacillus plantarum LP-115) because we hold no interaction data for them. Altogether, these interactions span 182 individual medications.
To see whether your specific prescriptions are affected, use the medication checker on this page. If you take antibiotics, talk to your pharmacist about the best timing for this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Max Potency Probiotic Pearls 5 Billion?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Max Potency Probiotic Pearls 5 Billion interact with 182 drugs. Click any drug to see the details.
2 of the 4 ingredients in Max Potency Probiotic Pearls 5 Billion interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium longum BB536 Howaru
AmikacinAmikin, Arikayce
How Amikacin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amikacin interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amoxicillin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amoxicillin Veterinary interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amoxicillin, Clavulanate Potassium interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Amphotericin, Tetracycline interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Ampicillin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Ampicillin, Sulbactam interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Avibactam Sodium, Ceftazidime interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Azithromycin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Aztreonam interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Bacampicillin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Bacitracin interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Benznidazole interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Capreomycin interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Carbenicillin Indanyl Sodium interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefaclor interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefadroxil interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefamandole interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefazolin interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefdinir interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefditoren Pivoxil interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefepime interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefiderocol Sulfate Tosylate interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefixime interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefmetazole interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefonicid interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
HowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefoperazone interactionBifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Max Potency Probiotic Pearls 5 Billion — through 2 ingredients. Tap an ingredient for the detail:
Bifidobacterium Longum Bb536Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum Bb536 + Cefotaxime interactionHowaruAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Howaru + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Max Potency Probiotic Pearls 5 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium longum BB536
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Howaru
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Max Potency Probiotic Pearls 5 Billion, from the product label.
Nature's Way
See all Nature's Way products- Name
- Nature's Way Brands, LLC
- City
- Green Bay
- State
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Max Potency Probiotic Pearls 5 Billion by Nature's Way: Common Questions
Does Max Potency Probiotic Pearls 5 Billion by Nature's Way interact with any medications?
How can one product interact with so many drugs?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Max Potency Probiotic Pearls 5 Billion’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Max Potency Probiotic Pearls 5 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
- Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
- Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
- Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
- Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
- Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
- Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed
See these in context on the Bifidobacterium Longum monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC