Interactions on record — worth a quick check against your medications. Based on 5 of 9 ingredients. Check your meds →
Dietary supplement

Pumpageddon Peach Rings Ingredients & Drug Interactions

by Frontline Formulations

Pumpageddon Peach Rings label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pumpageddon Peach Rings against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pumpageddon Peach Rings is a dietary supplement by Frontline Formulations with 9 active ingredients. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 1,150 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioperine Black Pepper (Piper nigrum) extract, Agmatine Sulfate, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pumpageddon Peach Rings by Frontline Formulations

Ask about any prescription or over-the-counter medication and we check it for interactions with Pumpageddon Peach Rings by Frontline Formulations — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pumpageddon Peach Rings by Frontline Formulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Pumpageddon Peach Rings has 9 active ingredients. Agmatine sulfate and beta-alanine are amino acid derivatives — agmatine may support blood vessel function and beta-alanine is used for athletic performance.

L-citrulline malate is another amino acid compound, converted in your body to L-arginine, which supports blood flow and exercise performance. Sodium provides electrolyte balance for hydration.

Black pepper extract contains piperine, a compound that enhances absorption of other nutrients. Three other actives — AstraGin, S7, and Nitrosigine — are proprietary blends or branded ingredients; Hydromax is a hydration agent.

The powder also contains inactive ingredients like sucralose and acesulfame potassium (sweeteners), silicon dioxide, and colorants.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: athletic performance and exercise endurance.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, Muscle strength, Fatigue, muscle pump — and 2 related terms.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Physical performance.
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.

Beta-alanine and L-citrulline malate are both possibly effective for athletic performance and physical performance, based on clinical evidence. Agmatine sulfate, sodium, black pepper, and the proprietary ingredients (AstraGin, S7, Nitrosigine, Hydromax) lack reliable evidence for the conditions they're claimed to address — the data shows insufficient evidence to rate them.

So if you're looking to boost exercise output, the two amino acids have some support; beyond that, what this product does is not yet established in our data.

The evidence, ingredient by ingredient Agmatine Beta-alanine L-citrulline Sodium Black Pepper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine sulfate appears generally well tolerated, but long-term safety in humans hasn't been studied well. Beta-alanine and L-citrulline are generally well tolerated in healthy adults.

The most common side effect of beta-alanine is a harmless pins-and-needles tingling (paresthesia) on the scalp and body, starting within 20 minutes and lasting about an hour — it's dose-dependent and mild at lower amounts. Agmatine can cause diarrhea, nausea, and indigestion in some people; black pepper may cause a burning aftertaste or indigestion.

Sodium at high levels can worsen high blood pressure, heart disease, and kidney disease over time, though normal dietary amounts are fine. Beta-alanine, L-citrulline, and black pepper lack enough safety data for pregnancy — the facts advise against their use during pregnancy and breastfeeding.

Agmatine also advises against use in pregnancy and breastfeeding. Sodium's safety in pregnancy is listed as possibly unsafe; talk with your doctor before taking any of these if you're pregnant or nursing.

Side effects, ingredient by ingredient Agmatine Beta-alanine L-citrulline Sodium Black Pepper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Black Pepper, L-citrulline, Sodium, Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,151 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Pumpageddon Peach Rings, double-check with your doctor or pharmacist if you take any blood pressure medication (major interaction risk with agmatine, L-citrulline, and sodium), diabetes medication (agmatine may lower blood sugar), erectile dysfunction medication like sildenafil (L-citrulline can lower blood pressure further), or any of these: seizure medications (phenytoin), antibiotics (rifampin), antivirals (nevirapine), immunosuppressants (cyclosporine), heart medications (propranolol, atorvastatin), sedatives (pentobarbital), asthma medication (theophylline), lithium, corticosteroids, HIV antivirals (didanosine), or bowel-cleansing products. No interactions are documented for the three ingredients we could not check — AstraGin, S7, and Nitrosigine — but that's because we hold no data for them, not proof they're safe with your medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpageddon Peach Rings is aimed at people looking to boost athletic performance, since beta-alanine and L-citrulline have some evidence for that use. If you take blood pressure medication, diabetes medication, or any of the other drugs black pepper interacts with — or if you're pregnant, nursing, or have heart, kidney, or blood pressure concerns — talk with your doctor or pharmacist before starting.

The tingling from beta-alanine is harmless, but worth knowing about. Use your interaction checker below or check in with your own doctor or pharmacist before you add this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpageddon Peach Rings, straight from the product label.

Brand Frontline Formulations
Net contents 15.69 Ounce(s); 445 Gram(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 265384
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpageddon Peach Rings by Frontline Formulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
17.8 Gram(s)
Maximum serving Sizes:
17.8 Gram(s)
Servings per container
25
IngredientAmount% DV
Agmatine Sulfate750 mg--
Beta Alanine3000 mg--
AstraGin502 mg--
L-Citrulline Malate8000 mg--
Sodium300 mg12%
S7520 mg--
Nitrosigine1200 mg--
Hydromax2500 mg--
Bioperine Black Pepper (Piper nigrum) extract5 mg--

Other ingredients: Natural & Artificial flavors, Silicon Dioxide, Sucralose, Acesulfame Potassium, FD&C Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stimulant free

Vasodilator Insane endurance Skin splitting pumps

General Statements

25 servings

FDA Statement of Identity

Dietary Supplement

Formula

1200 mg Nitrosigine 50 mg S7 2500 mg HydroPrime 50 mg AstraGin 5 mg BioPerine

Suggested/Recommended/Usage/Directions

Suggested Use: Mix 1 scoop (17.8 g) in 8-12 oz of cold water and mix well. Take 20-30 minutes prior to exercise.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pumpageddon Peach Rings by Frontline Formulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pumpageddon Peach Rings label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pumpageddon Peach Rings by Frontline Formulations

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size17.8 Gram(s) Dosage formPowder Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Agmatine Sulfate

Interacts with
258 drugs
750 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

Beta Alanine

No known
interactions
3000 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta Alanine monograph & interactions

AstraGin

502 mg per serving Form: Astragalus membranaceous Root Extract, Panax notoginseng Root Extract

L-Citrulline Malate

Interacts with
178 drugs
8000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline Malate monograph & interactions

Sodium

Interacts with
205 drugs
300 mg per serving Form: pink Himalayan Sea Salt

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

S7

520 mg per serving Form: Blueberry, Broccoli, Green Coffee bean extract, Green Tea extract, Kale, Tart Cherry, Turmeric extract

Nitrosigine

1200 mg per serving

Hydromax

2500 mg per serving Form: Glycerol, Powder

Bioperine Black Pepper (Piper nigrum) extract

Interacts with
1,019 drugs
5 mg per serving

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to he...

Bioperine Black Pepper (Piper nigrum) extract monograph & interactions

Other (inactive) ingredients: Natural & Artificial flavors, Silicon Dioxide, Sucralose, Acesulfame Potassium, FD&C Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpageddon Peach Rings by Frontline Formulations Drug Interactions

Want to check YOUR meds against Pumpageddon Peach Rings?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,150Drugs
1,107 Moderate 43 Minor

Ingredients driving the most interactions

Bioperine Black Pepper (Piper nigrum) extract 1,019
Agmatine Sulfate 258
Sodium 205
L-Citrulline Malate 178

Individual Drug Interactions

The ingredients in Pumpageddon Peach Rings interact with 1,150 drugs. Click any drug to see the details.

4 of the 9 ingredients in Pumpageddon Peach Rings interact with drugs. Each result below shows which ingredient is responsible. Bioperine Black Pepper (Piper nigrum) extract Agmatine Sulfate Sodium L-Citrulline Malate

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpageddon Peach Rings with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioperine Black Pepper (Piper nigrum) extract17 drug types · 1,019 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation. This has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, black pepper might increase blood levels of atorvastatin.
Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold. This has not been reported in humans.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, black pepper might increase the effects and side effects of cyclosporine.
In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
In vitro research suggests that some constituents of black pepper inhibit CYP2D6. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
In vitro research and pharmacokinetic simulation data suggest that piperine, a constituent of black pepper, as well as the pepper fruit seem to inhibit CYP3A4. This has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
Black pepper is thought to have diuretic properties.

Likelihood Probable Evidence D
Nevirapine (Viramune)

Black pepper might increase blood levels of nevirapine.
Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study.

Likelihood Probable Evidence D
P-Glycoprotein Substrates

Theoretically, black pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, black pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Black pepper might increase blood levels of phenytoin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin. Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin. Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper.

Likelihood Possible Evidence B
Propranolol (Inderal)

Black pepper might increase blood levels of propranolol.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Black pepper might increase blood levels of rifampin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence B
Theophylline

Black pepper might increase blood levels of theophylline.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline.

Likelihood Possible Evidence D
Amoxicillin (Amoxil, Trimox)

Theoretically, black pepper might increase the effects and side effects of amoxicillin.
Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin. This has not been reported in humans.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects. In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that black pepper induces CYP1A2. This has not been reported in humans.

Likelihood Possible Evidence D
Bioperine Black Pepper (Piper nigrum) extract full monograph & interactions

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

L-Citrulline Malate2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline Malate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pumpageddon Peach Rings, from the product label.

Frontline Formulations

See all Frontline Formulations products
Name
Frontline Formulations
Pharmacist Counseling Corner

Pumpageddon Peach Rings by Frontline Formulations: Common Questions

Does Pumpageddon Peach Rings by Frontline Formulations interact with any medications?
Yes. Based on its ingredients, Pumpageddon Peach Rings has a known interaction with 1,150 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpageddon Peach Rings contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-alanine do in this product?
Beta-alanine is an amino acid that research suggests may help with athletic performance and physical performance — the data shows it's possibly effective for those uses. Most people taking it notice a harmless tingling sensation on the skin, especially on the scalp, starting around 20 minutes after a dose.
I get that tingly, pins-and-needles feeling from this — is that normal?
Yes, that's the beta-alanine. It causes paresthesia (a pins-and-needles feeling) that's completely harmless. It usually starts on your scalp within about 20 minutes, spreads to other parts of your body, and fades in about an hour. The intensity depends on how much you take — lower doses cause it less often.
Is it safe to take this while pregnant or breastfeeding?
There isn't enough safety data to know either way for most of the active ingredients in this product. The facts advise against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, nursing, or planning to become pregnant.
Can I use this if I take blood pressure medication?
You need to check with your doctor or pharmacist first. Three ingredients in this product — agmatine sulfate, L-citrulline malate, and sodium — can theoretically lower blood pressure further, which could be risky if you're already on a blood pressure drug. Don't start this without clearing it with your own healthcare provider.
What's the black pepper extract for?
Black pepper extract provides piperine, a compound that enhances how your body absorbs other nutrients in the formula. However, piperine can also increase how your body absorbs and processes certain medications, so it's one reason to check your drug list before starting — especially if you take seizure, antibiotic, antiviral, or heart medications.
Does this have fillers or just active ingredients?
The powder contains inactive ingredients like sweeteners (sucralose and acesulfame potassium), silicon dioxide, and colorants. These are excipients that help with taste and texture — pretty standard for supplement powders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpageddon Peach Rings label
Go deeper

The Full Monographs Behind Pumpageddon Peach Rings’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Black Pepper

Interacts with 1,019 drugs

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to help the body absorb other ingredients (li...

Read the full Black Pepper monograph →
Sources

Sources & How We Checked

Pumpageddon Peach Rings's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 91 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Beta-alanine 13 references
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L-citrulline 8 references
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See these in context on the Sodium monograph →

Black Pepper 29 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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