Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Pure Glutamine Peptides Ingredients & Drug Interactions

by Pure Advantage

Pure Glutamine Peptides label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pure Glutamine Peptides against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pure Glutamine Peptides is a dietary supplement by Pure Advantage with 2 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glutamine Peptides. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Pure Glutamine Peptides by Pure Advantage

Ask about any prescription or over-the-counter medication and we check it for interactions with Pure Glutamine Peptides by Pure Advantage — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Pure Glutamine Peptides by Pure Advantage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Glutamine Peptides contains one active ingredient: glutamine peptides, which are short chains of the amino acid glutamine. Your body uses glutamine for muscle recovery, immune function, and gut health, especially during stress, illness, or intense physical demand.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle mass, immune function, physical performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Critical illness (trauma), Postoperative recovery, Postoperative infection, HIV/AIDS-related wasting — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Burns.

The evidence for glutamine peptides is strongest for sickle cell disease, where it's rated Effective. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is Possibly Effective—meaning there's some promising data, but we'd like to see more rigorous trials.

The supplement hasn't been studied enough yet for other common uses.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glutamine is generally well tolerated by healthy adults. The most common side effects are gastrointestinal—belching, bloating, flatulence, nausea, diarrhea, and abdominal pain—especially at high doses (10–30 grams daily).

A few cases of dizziness and headache have been reported, and in rare instances, people with bipolar disorder taking glutamine have developed mania or hypomania. If you have kidney or liver disease, use glutamine only under medical supervision.

There isn't enough reliable safety data to recommend supplement doses during pregnancy or breastfeeding; talk with your doctor about whether it's right for you.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, talk with your doctor or pharmacist if you take anticonvulsants (seizure medications). Glutamine may theoretically reduce how well these drugs work, though this hasn't been confirmed in humans yet.

A pharmacist or doctor can help you decide if it's safe for you alongside your current medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Glutamine peptides may help with sickle cell disease and recovery from surgery or critical illness, though evidence for other uses is still building. If you take any seizure medication, check with your doctor or pharmacist before starting—and if you have kidney or liver problems, get clearance first.

A few people experience digestive upset or headache; start at a lower dose if you do. It's a good idea to discuss this with your own healthcare provider before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pure Glutamine Peptides, straight from the product label.

Brand Pure Advantage
Barcode (UPC) 646448508687
Net contents 1.1 lbs; 500 Gram(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231506
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pure Glutamine Peptides by Pure Advantage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
100
UPC/BARCODE
646448508687
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates0 Gram(s)--
Calories from Fat0 Calorie(s)--
Protein5 Gram(s)10%
Total Fat0 Gram(s)--
Glutamine Peptides5 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Take the pure advantage

Glutamine is the most abundant free amino acid found in muscle tissue. Studies have shown that strenuous exercise and trauma are linked to a drop in plasma glutamine levels and impaired immune function. During times of stress, the body experiences an increase in free radicals, resulting in a decrease in the number of antioxidants to fight them. Studies have shown that increased plasma levels of glutamine can reduce the rise of free radicals, which decreases the risk of infection or stressed induced illness.

So get the advantage with Pure Advantage

Please recycle

GLN

Formula

Glutamine peptides have been shown to be absorbed faster, and are more bio-available than standard l-glutamine powder. Unlike free form l-glutamine, peptide-bound glutamine is a scientific process that binds l-glutamine to peptides, making it stable and doubling its absorption rate.

5g protein 5g PepForm glutamine peptides 20 calories

PepForm

Glutamine peptides

Formulation

Supplementing with glutamine may help maintain muscle mass, help the immune system and improve physical performance.

0g carbs 0g trans fat 0g cholesterol 0g saturated fat

Contains no sugar, starch, yeast, wheat, gluten, corn, soy, egg or preservatives.

Precautions

Allergen information: contains ingredients produced from milk.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place.

Suggested Use: As a dietary supplement, mix 1 tsp (5 grams) into your favorite protein shake after training or before bedtime. Best results are achieved by using 10 grams per day. Since Glutamine Peptides are not instantized, the use of a shaker cup or blender may be required.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Made in a FDA Registered Facility Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pure Glutamine Peptides by Pure Advantage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pure Glutamine Peptides label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pure Glutamine Peptides by Pure Advantage

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

5 Gram(s) per serving

Glutamine Peptides

Interacts with
50 drugs
5 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

Glutamine Peptides monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pure Glutamine Peptides by Pure Advantage Drug Interactions

Want to check YOUR meds against Pure Glutamine Peptides?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Glutamine Peptides 50

Individual Drug Interactions

The ingredients in Pure Glutamine Peptides interact with 50 drugs. Click any drug to see the details.

1 of the 2 ingredients in Pure Glutamine Peptides interact with drugs. Each result below shows which ingredient is responsible. Glutamine Peptides

Each ingredient & the kinds of drugs it affects

For each ingredient in Pure Glutamine Peptides with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glutamine Peptides1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
Glutamine Peptides full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pure Glutamine Peptides, from the product label.

Pure Advantage

See all Pure Advantage products
Name
Nutritional Brands
City
Phoenix
State
AZ
ZipCode
85085
Phone Number
1-800-798-0707
Web Address
nbpure.com
Pharmacist Counseling Corner

Pure Glutamine Peptides by Pure Advantage: Common Questions

Does Pure Glutamine Peptides by Pure Advantage interact with any medications?
Yes. Based on its ingredients, Pure Glutamine Peptides has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pure Glutamine Peptides contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glutamine peptides safe during pregnancy and breastfeeding?
Glutamine is rated Likely Safe in pregnancy, so it's generally okay if your doctor recommends it. During breastfeeding, though, there isn't enough reliable safety information; talk with your doctor or pharmacist about whether it makes sense for you.
What are the most common side effects?
Digestive side effects are most common—belching, bloating, flatulence, nausea, diarrhea, and abdominal pain, especially at higher doses. Headache and dizziness are less common. These often improve if you reduce your dose.
Does glutamine peptides actually work?
It's Effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is Possibly Effective—meaning it may help, but we need more research to be sure.
Can I take this if I have kidney or liver disease?
You can, but only under your doctor's supervision. If you have either condition, talk with your doctor before starting.
How much glutamine should I take?
The product facts don't specify a dosage. Follow the label on your bottle, or talk with your pharmacist or doctor about the right dose for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pure Glutamine Peptides is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pure Glutamine Peptides label
Go deeper

The Full Monographs Behind Pure Glutamine Peptides’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

Pure Glutamine Peptides's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team