Quantum Digest Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Quantum Digest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Quantum Digest is a dietary supplement by Quantum Nutrition Labs with 11 active ingredients. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 617 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Noni, Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Quantum Digest by Quantum Nutrition Labs
Ask about any prescription or over-the-counter medication and we check it for interactions with Quantum Digest by Quantum Nutrition Labs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Quantum Digest by Quantum Nutrition Labs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Quantum Digest contains 11 ingredients, including digestive enzymes and plant extracts. The active ingredients are apple cider vinegar, pepsin, noni, cellulase, amylase, lipase, lactase, protease, and diastase enzymes — designed to support digestion.
The inactive ingredients are rice extract, potato dextrin, tapioca dextrin, cellulose, and water, which serve as fillers and binding agents in the capsule.
Does it work?
Strong evidence
The evidence for most of Quantum Digest's ingredients is not established in the data we hold. Apple cider vinegar, noni, and the proteolytic enzymes all show insufficient reliable evidence to rate them for their claimed uses.
Lactase enzyme is the one exception — it is effective for lactose intolerance. For the other ingredients and conditions listed on the label, we don't have strength-of-evidence ratings on file.
How safe is it?
Well-documented data
Apple cider vinegar is well tolerated in food amounts, but large or long-term medicinal doses may cause harm — including low potassium (hypokalemia), high renin levels, and bone loss in rare cases. Topically it can cause chemical burns.
Noni is generally well tolerated in moderate amounts, but serious liver injury has been reported rarely, and its high potassium content is a concern. Pepsin and the other proteolytic enzymes may cause digestive upset or, rarely, allergic reactions like asthma or rhinoconjunctivitis in susceptible people.
Lactase is generally well tolerated; one case of allergic contact dermatitis has been reported. Lipase carries no reported adverse effects in adults, but safety data in pregnancy and breastfeeding is limited.
Meds to double-check
Moderate interaction found
Before you start Quantum Digest, check with your pharmacist if you take diuretics, digoxin, insulin, blood pressure medications (ACE inhibitors, ARBs, or antihypertensive drugs), warfarin or other blood thinners, phenytoin (an anti-seizure drug), or any drug that can damage the liver — these carry Moderate interactions with apple cider vinegar and/or noni. Ranitidine (for acid reflux) has a Minor interaction with noni.
No interactions are documented for the enzymes we could check.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Quantum Digest is a multi-enzyme digestive supplement. If you take blood pressure medications, diuretics, heart or seizure medications, blood thinners, or insulin, you need to check your exact drugs against this product's interactions before starting — particularly because of apple cider vinegar and noni.
Talk to your pharmacist or doctor before use if you're pregnant, breastfeeding, or have a serious digestive condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 7 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Quantum Digest, straight from the product label.
| Brand | Quantum Nutrition Labs |
|---|---|
| Barcode (UPC) | 807735129453 |
| Net contents | 60 Plant-Source Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 303456 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Quantum Digest by Quantum Nutrition Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Apple Cider Vinegar | 0 NP | -- |
| Pepsin | 0 NP | -- |
| Noni | 0 NP | -- |
| Cellulase Enzyme | 0 NP | -- |
| Amylase Enzyme | 0 NP | -- |
| Lipase Enzyme | 0 NP | -- |
| Lactase Enzyme | 0 NP | -- |
| Plant-Gest Support | 95 mg | -- |
| Opti-pH Protease | 0 NP | -- |
| Quantum Enzyme Blend | 206 mg | -- |
| Diastase Enzyme | 0 NP | -- |
| Protease Enzyme | 0 NP | -- |
| Invertase Enzymes | 0 NP | -- |
Other ingredients: Rice extract, Potato Dextrin, Tapioca Dextrin, Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule per meal, 3 times daily with meals.
Formulation
Fully Active Vegetarian Enzymes
Full spectrum digestive support
Pure Vegan
Purity Verified FDA-Monitored cGMP Facility
No Added Magnesium Stearate Tested for Adulterants
Formula
Fully Active Vegetarian Enzymes Highly effective, full spectrum enzyme formula for digestive support and cleansing. Enzyme deficiencies are linked to occasional fatigue, minor pain, moodiness & more.
Full spectrum digestive enzyme with Pepsin
Precautions
Tamper Seal: Use only if seal is intact.
Consult your health practitioner if you are pregnant/nursing, taking medication or have a medical condition, before taking this product.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Scan to Discover More
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Quantum Digest by Quantum Nutrition Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Quantum Digest by Quantum Nutrition Labs
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Plant-Gest Support
- › Apple Cider Vinegar
- › Pepsin
- › Noni
Quantum Enzyme Blend
- › Cellulase Enzyme
- › Amylase Enzyme
- › Lipase Enzyme
- › Lactase Enzyme
- › Opti-pH Protease
- › Diastase Enzyme
- › Protease Enzyme
- › Invertase Enzymes
Other (inactive) ingredients: Rice extract, Potato Dextrin, Tapioca Dextrin, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
Quantum Digest by Quantum Nutrition Labs Drug Interactions
HelloPharmacist Interaction Report
Quantum Digest by Quantum Nutrition Labs contains ingredients with documented interactions with several medication types.
Apple cider vinegar poses the most serious concerns: it interacts with diuretic drugs (water pills), digoxin (a heart medication), and insulin, all at Moderate severity — chiefly because it may lower potassium levels, which can cause dangerous heart effects or worsen low blood sugar (hypoglycemia). Noni, another active ingredient, also carries Moderate-severity interactions with blood pressure medications, liver-toxic drugs, potassium-sparing diuretics, ACE inhibitors, ARBs, warfarin (a blood thinner), and phenytoin (an anti-seizure drug), plus a Minor interaction with ranitidine (an acid-reflux medication).
The risk with noni centers on its high potassium content and its potential to reduce the effectiveness of blood thinners and seizure medications. Altogether, these interactions span 600 individual medications.
Pepsin, lipase, lactase, and the protease enzymes are checked with no documented interactions. We could not check cellulase, amylase, diastase, or invertase enzymes — no monograph data is on file for them.
Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Quantum Digest?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Quantum Digest interact with 617 drugs. Click any drug to see the details.
2 of the 11 ingredients in Quantum Digest interact with drugs. Each result below shows which ingredient is responsible. Noni Apple Cider Vinegar
Acetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Pamabrom, Pyrilamine interactionApple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Acetazolamide interactionApple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Acetohexamide interactionApple Cider VinegarAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Apple Cider Vinegar + Acetohexamide interactionAdagrasibKrazati
How Adagrasib interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Adagrasib interactionAldesleukinProleukin
How Aldesleukin interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Aldesleukin interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Alectinib Hydrochloride interactionAliskirenTekturna
How Aliskiren interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Aliskiren interactionAllopurinolCaplenal, Cosuric, Rimapurinol, Zyloprim, Zyloric
How Allopurinol interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Allopurinol interactionAlogliptinNesina
How Alogliptin interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Alogliptin interactionApple Cider VinegarAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Apple Cider Vinegar + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Alogliptin, Pioglitazone interactionApple Cider VinegarAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Apple Cider Vinegar + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs, Potassium-sparing Diuretics Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Quantum Digest — through 2 ingredients. Tap an ingredient for the detail:
NoniPotassium-sparing Diuretics, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Read the full Noni + Amiloride, Hydrochlorothiazide interactionApple Cider VinegarDiuretic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
Read the full Apple Cider Vinegar + Amiloride, Hydrochlorothiazide interactionAminosalicylic AcidPaser
How Aminosalicylic Acid interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Aminosalicylic Acid interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
Read the full Noni + Amiodarone interactionAmlodipineNorliqva
How Amlodipine interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs, Ace Inhibitors (aceis) Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Quantum Digest — through 1 ingredient. Tap an ingredient for the detail:
NoniAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Read the full Noni + Amlodipine, Celecoxib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Quantum Digest with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Noni
Ace Inhibitors (Aceis)
Theoretically, combining noni and ACE inhibitors might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ACE inhibitors, which can also increase potassium levels.
Angiotensin Receptor Blockers (Arbs)
Theoretically, combining noni and ARBs might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with ARBs, which can also increase potassium levels.
Antihypertensive Drugs
Theoretically, noni may increase the risk of hypotension when used in combination with antihypertensive drugs.
Preliminary clinical research suggests that drinking noni juice can reduce blood pressure in individuals with hypertension.
Hepatotoxic Drugs
Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.
There is concern that noni might cause hepatotoxicity in some patients. Advise patients against combining noni with potentially hepatotoxic drugs.
Phenytoin (Dilantin)
Theoretically, taking noni fruit juice concomitantly with phenytoin may lower phenytoin levels and increase the risk of seizures.
In one case report, an adult taking phenytoin for partial seizures experienced low serum phenytoin levels while taking noni juice 90-200 mL daily. Serum phenytoin levels increased after decreasing noni juice consumption; similarly, serum phenytoin levels decreased after increasing noni juice consumption. Some researchers believe noni juice may induce cytochrome P450 2C9 enzymes, which would decrease phenytoin levels, but this has not been well studied. Patients may need additional monitoring when starting or stopping noni juice supplementation.
Potassium-Sparing Diuretics
Theoretically, combing noni and a potassium-sparing diuretic might increase the risk of hyperkalemia.
Noni juice contains significant amounts of potassium, about 6 mEq/100 mL juice. This may increase the risk for hyperkalemia when used in conjunction with potassium-sparing diuretics, which can also increase potassium levels.
Warfarin (Coumadin)
Theoretically, taking noni juice concomitantly with warfarin might decrease the effectiveness of warfarin.
In one case, a 41-year-old patient stabilized on warfarin had a decreased international normalized ratio (INR) following consumption of a specific commercial noni juice product (Noni juice 4 Everything). While the patient was still taking noni juice, an increase in warfarin dose did not produce an increase in INR. However, it should be noted that this particular product contained extracts and derivatives from more than 115 components, many of which contained vitamin K. Furthermore, vitamin K was listed as a separate ingredient of the product, suggesting that the product was possibly fortified with vitamin K. It has not been verified that noni fruit alone contains a significant amount of vitamin K or interacts with warfarin.
Ranitidine (Zantac)
Taking noni fruit with ranitidine might increase the levels and clinical effects of ranitidine.
Clinical evidence shows that taking an aqueous extract of noni fruit 30 minutes prior to taking a single oral dose of ranitidine can increase the rate of absorption and plasma concentration of ranitidine.
Apple Cider Vinegar
Digoxin (Lanoxin)
Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.
Diuretic Drugs
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.
Insulin
Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.
Antidiabetes Drugs
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.
Brand information
Manufacturer and brand details for Quantum Digest, from the product label.
Quantum Digest by Quantum Nutrition Labs: Common Questions
Does Quantum Digest by Quantum Nutrition Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product actually help with digestion?
Is apple cider vinegar safe to take every day?
Can I take this while I'm pregnant?
Can I take this while breastfeeding?
What is noni and why is it in this?
Could I have an allergic reaction to this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Quantum Digest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Quantum Digest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Apple Cider Vinegar
Interacts with 162 drugsApple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...
Read the full Apple Cider Vinegar monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographNoni
Interacts with 542 drugsNoni is a tropical fruit used widely in folk medicine and sold mostly as a juice or supplement, but solid human evidence for its many claimed benefits is limited. While moderate juice intake...
Read the full Noni monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph →Sources & How We Checked
Quantum Digest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 32 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Apple Cider Vinegar 11 references
- Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
- Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
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- Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
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Proteolytic Enzymes (proteases) 3 references
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- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Noni 16 references
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- Issell, B. F., Gotay, C. C., Pagano, I., and Franke, A. A. Using quality of life measures in a Phase I clinical trial of noni in patients with advanced cancer to select a Phase II dose. J.Diet.Suppl 2009;6(4):347-359. PubMed
- Palu AK, Santiago RA West B Kaluhiokalani N Jensen J. The Effects of Morillda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. ACS SYMPOSIUM SERIES 993 2008;
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
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- Yu-Chan Kang, Ming-Hong Chen, Shung-Lon Lai. Potentially Unsafe Herb-drug Interactions Between a Commercial Product of Noni Juice and Phenytoin- A Case Report. Acta Neurol Taiwan. 2015 Jun;24(2):43-6.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
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