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Dietary supplement

Royal Jelly Maximum Strength Ingredients & Drug Interactions

by Swanson

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Royal Jelly Maximum Strength is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly 3X. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Royal Jelly Maximum Strength by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Royal Jelly Maximum Strength contains one active ingredient: royal jelly 3X (a concentrated form). Royal jelly is a nutrient-rich secretion made by honeybees.

The product also contains several inactive ingredients—medium-chain triglycerides, gelatin, glycerin, yellow beeswax, purified water, and sunflower lecithin—that make up the softgel capsule and help deliver the royal jelly.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Royal Jelly's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports immune health and boosts energy levels.
  • We looked for evidence on: Coronavirus disease 2019 (COVID-19), Cancer-related fatigue, Chemotherapy-related fatigue.
  • The closest evidence on file: Royal Jelly is rated "Insufficient Reliable Evidence To Rate" for Cancer-related fatigue (Natural Medicines).
  • Also on file: Royal Jelly is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-related fatigue, Coronavirus disease 2019 (COVID-19).

Royal jelly is possibly effective for menopausal symptoms, meaning some evidence suggests it may help with hot flashes and related discomfort. However, the evidence we hold shows it's possibly ineffective for allergic rhinitis (hay fever), physical performance, and diabetes.

For hair loss (androgenic alopecia), there isn't enough reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal jelly is generally well tolerated in most people, but it can cause serious allergic reactions in anyone with a history of asthma or atopy (a tendency toward allergic conditions). Common allergic symptoms include itching, hives, eczema, shortness of breath, and oral allergy syndrome.

In rare cases, severe allergic reactions—anaphylaxis, status asthmaticus (severe asthma attack), and even death—have been reported in people with asthma or atopy. There's also one rare case of bleeding in the colon after ingestion, though symptoms resolved within two weeks after stopping.

The safety data advises against using royal jelly during pregnancy and while breastfeeding because there isn't enough information to know whether it's safe.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on warfarin (Coumadin)—royal jelly may increase bleeding risk. Also confirm any blood pressure medications you're taking, since royal jelly may lower blood pressure further.

If you take any other prescription drugs, use the interaction checker on this page to verify them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Jelly Maximum Strength may be worth considering if you're dealing with menopausal symptoms and you don't have asthma or a history of allergies. However, if you take warfarin or any blood pressure medication, you need to check with your doctor or pharmacist first — the interaction risk is real.

Anyone with asthma or atopic allergies should be especially cautious, as allergic reactions can be serious.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Jelly Maximum Strength, straight from the product label.

Brand Swanson
Barcode (UPC) 087614116013
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 212558
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Jelly Maximum Strength by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
087614116013
IngredientAmount% DV
Royal Jelly 3X333.33 mg--

Other ingredients: Medium-Chain Triglycerides, Gelatin, Glycerin, yellow Beeswax, purified Water, Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports immune health Boosts energy levels Maximizes vitality and promotes overall wellbeing

Energy support

General Statements

Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one softgel one to two times per day with water.

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Contains sulfites, tree nuts (coconut).

Storage

Store in a cool, dry place. Do not refrigerate.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Royal Jelly Maximum Strength by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Royal Jelly Maximum Strength by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Royal Jelly 3X

Interacts with
174 drugs
333.33 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly 3X monograph & interactions

Other (inactive) ingredients: Medium-Chain Triglycerides, Gelatin, Glycerin, Yellow Beeswax, Purified Water, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Jelly Maximum Strength by Swanson Drug Interactions

Want to check YOUR meds against Royal Jelly Maximum Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Jelly Maximum Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly 3X2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Royal Jelly Maximum Strength, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Royal Jelly Maximum Strength by Swanson: Common Questions

Does Royal Jelly Maximum Strength by Swanson interact with any medications?
Yes. Based on its ingredients, Royal Jelly Maximum Strength has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Jelly Maximum Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have asthma or allergies?
If you have a history of asthma or atopy (a tendency toward allergic conditions), you should be very cautious. Royal jelly can trigger allergic symptoms like itching, hives, shortness of breath, and in rare cases, severe reactions like anaphylaxis. Talk to your doctor before taking it.
Does royal jelly really help with hot flashes?
Royal jelly is possibly effective for menopausal symptoms, which means some evidence suggests it may help. But it's not a sure thing — the evidence is mixed and not strong.
Is it safe to take while pregnant or breastfeeding?
The safety data advises against it during both pregnancy and breastfeeding because there isn't enough information to know either way. Talk to your doctor or pharmacist for personalized advice about your situation.
What are the most common side effects?
In most people, royal jelly is well tolerated. People with asthma or allergies are at higher risk for side effects like itching, hives, eczema, and shortness of breath. A few people have also reported stomach issues like bloody diarrhea, though that's rare.
What's the '3X' on the label mean?
The '3X' indicates this is a concentrated form of royal jelly, meaning the active ingredient is more potent than a standard version.
Does this have any fillers or extra ingredients I should know about?
The softgel capsule contains medium-chain triglycerides, gelatin, glycerin, yellow beeswax, purified water, and sunflower lecithin—all inactive ingredients that help make up the capsule itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Royal Jelly Maximum Strength is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Jelly Maximum Strength label
Go deeper

The Full Monographs Behind Royal Jelly Maximum Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Royal Jelly Maximum Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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