Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Sheep Sorrel Ingredients & Drug Interactions

by Herbs Etc.

Sheep Sorrel label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sheep Sorrel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sheep Sorrel is a dietary supplement by Herbs Etc. with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, digestive upset, fever.Based on those ingredients, 169 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sheep Sorrel. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sheep Sorrel by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Sheep Sorrel by Herbs Etc. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Sheep Sorrel by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This liquid contains one active ingredient: sheep sorrel. It's a plant traditionally used for bronchitis, breast health, and sinus issues, though the evidence for these uses is not yet established in our data.

The liquid is 40% grain alcohol and purified water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Sorrel product and its label doesn't state a use — see Sorrel's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have reliable evidence to support sheep sorrel for bronchitis, breast cancer, or rhinosinusitis. The data we hold rates all three as having insufficient evidence.

That doesn't mean it doesn't work — just that studies strong enough to prove it aren't in our files.

The evidence, ingredient by ingredient Sorrel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sheep sorrel is generally well tolerated in food amounts, but concentrated medicinal doses raise two concerns. First, it's high in oxalates, compounds that can stress your kidneys at large doses — kidney damage and kidney stones have been reported in people taking substantial amounts.

Second, if you're allergic to weed pollen, you may react to sorrel pollen too; about 1 in 5 weed-pollen-allergic people show cross-sensitivity. Nausea and an unpleasant aftertaste have been reported when sorrel was combined with other herbs.

There isn't enough safety data on medicinal amounts during breastfeeding, so it's best to avoid concentrated supplements while nursing.

Side effects, ingredient by ingredient Sorrel

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sorrel.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 169 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with us about blood thinners and antiplatelet drugs (like warfarin, clopidogrel, or aspirin therapy) — sorrel may increase their effects. Also double-check any OATP substrate medications, including fexofenadine and others absorbed through those transporters.

If you're unsure whether your drug is affected, use the medication checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Sheep sorrel is used traditionally for respiratory and women's health concerns, but evidence for those uses isn't established. If you take blood thinners, allergy meds, or medications transported by OATP, this product may interfere — check your exact drugs with the tool on this page.

Talk with your pharmacist or doctor before starting, especially if you have kidney concerns or are breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sheep Sorrel, straight from the product label.

Brand Herbs Etc.
Net contents 8 fl. Oz.; 236 mL
Market status On market
Date entered into DSLD Sep 25, 2015
DSLD ID 50454
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sheep Sorrel by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
Sheep Sorrel0 NP--

Other ingredients: 40% Grain Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Professional Strength

Dried herb extract

For dispensing purposes only

Herbal Single

FDA Statement of Identity

Fast-acting Dietary Supplement

General

99188

Formula

Rumex acetosella

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sheep Sorrel by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sheep Sorrel label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sheep Sorrel by Herbs Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0 Not Present Dosage formLiquid Amounts shown are per serving.

Sheep Sorrel

Interacts with
169 drugs
0 NP per serving

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for an...

Sheep Sorrel monograph & interactions

Other (inactive) ingredients: 40% Grain Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sheep Sorrel by Herbs Etc. Drug Interactions

Want to check YOUR meds against Sheep Sorrel?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
169Drugs
169 Moderate

Ingredients driving the most interactions

Sheep Sorrel 169

Individual Drug Interactions

The ingredients in Sheep Sorrel interact with 169 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sheep Sorrel interact with drugs. Each result below shows which ingredient is responsible. Sheep Sorrel

Each ingredient & the kinds of drugs it affects

For each ingredient in Sheep Sorrel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sheep Sorrel3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
Sheep Sorrel full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sheep Sorrel, from the product label.

Herbs Etc.

Name
Herbs, Etc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Sheep Sorrel by Herbs Etc.: Common Questions

Does Sheep Sorrel by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Sheep Sorrel has a known interaction with 169 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sheep Sorrel contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is sheep sorrel safe to take while I'm breastfeeding?
There isn't enough safety data on medicinal amounts during breastfeeding, so the data we hold advises against concentrated supplements while nursing. Talk with your pharmacist or doctor about whether food amounts are okay for your situation.
Can I take this if I have kidney problems?
Sheep sorrel is high in oxalates, which can stress your kidneys, especially at large or concentrated doses. If you have kidney disease or a history of kidney stones, check with your pharmacist or doctor before starting.
Will this help my bronchitis?
Sheep sorrel is used traditionally for bronchitis, but we don't have reliable evidence that it works for this. The research to prove it isn't in our data yet.
Can I take this if I'm allergic to ragweed or other weeds?
If you're allergic to weed pollen, you might react to sorrel pollen too — about 1 in 5 weed-pollen-allergic people show cross-sensitivity. Be cautious and watch for any allergic symptoms.
What are the side effects I should watch for?
At food amounts, sorrel is generally well tolerated. At medicinal doses, nausea and an unpleasant aftertaste have been reported (especially when mixed with other herbs). At large doses, kidney damage from high oxalate content is a concern.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sheep Sorrel is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sheep Sorrel label
Go deeper

The Full Monographs Behind Sheep Sorrel’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sorrel

Interacts with 169 drugs

Sorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its hig...

Read the full Sorrel monograph →
Sources

Sources & How We Checked

Sheep Sorrel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed

See these in context on the Sorrel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team