Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Sinupret Kids Syrup Sinus & Immune Ingredients & Drug Interactions

by Bioforce

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sinupret Kids Syrup Sinus & Immune is a dietary supplement by Bioforce with 5 active ingredients. Its ingredients are commonly taken for loss of appetite, indigestion and bloating, digestive bitter tonic.Based on those ingredients, 333 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gentian, Sorrel. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sinupret Kids Syrup Sinus & Immune by Bioforce

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Sinupret(R) proprietary blend” is a proprietary blend — the label gives one combined amount (880 mg) without saying how much of each component you get.

This syrup contains five active herbal ingredients: gentian, European elder, cowslip, sorrel, and European vervain. Together they're formulated to support sinus and immune function in children.

The product also contains inactive ingredients including water, maltitol (a sweetener), ethyl alcohol, and cherry flavor to make it palatable for kids.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Promotes nasal health and supports immune system.
  • We looked for evidence on: Rhinosinusitis, Sinusitis, Bronchitis, Sinus congestion, Upper respiratory support, Nasal congestion.
  • The strongest evidence on file: Cowslip is rated "Possibly Effective" for Sinusitis (Natural Medicines).
  • Also on file: Gentian is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis.
  • Also on file: Sorrel is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Rhinosinusitis.

The evidence for these ingredients is limited. Cowslip is rated possibly effective for sinusitis, suggesting some traditional use and research backing — though the data aren't conclusive.

The other ingredients — gentian, European elder, sorrel, and European vervain — either haven't been studied enough for their effectiveness in sinus or immune support, or the evidence we hold is insufficient to rate them. This doesn't mean they don't work; it means we just don't have solid clinical proof in the data we review.

The evidence, ingredient by ingredient Gentian Cowslip Sorrel

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gentian is generally well tolerated in small amounts, but it can upset your stomach and hasn't been studied at high doses. Some people using gentian in combination with other herbs have reported nausea, vomiting, diarrhea, and bloating.

Sorrel contains high levels of oxalates, which can be a concern at large or concentrated doses and may theoretically affect kidney function — though this is rare. Sorrel pollen can also trigger allergic reactions in people sensitive to weed pollen.

Cowslip is generally used in traditional teas, but human safety data are sparse and allergic reactions are possible. We have no reliable safety information for European Elder or European Vervain at this time.

Side effects, ingredient by ingredient Gentian Cowslip Sorrel

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Gentian, Sorrel.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 333 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving this syrup to your child, double-check any blood thinners or antiplatelet medications (like aspirin or warfarin) — sorrel may add to their effect. If your child takes blood pressure medication, check that too, since gentian may increase how much it lowers pressure.

Also verify any antihistamines, especially fexofenadine (Allegra), as sorrel may reduce their absorption. For European Elder and European Vervain, we hold no interaction data, so we cannot advise on those.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Sinupret Kids Syrup is a traditional herbal formula that may appeal to parents looking for plant-based sinus and immune support. If your child takes blood thinners, blood pressure medications, or antihistamines like fexofenadine, check with us or your pharmacist first — sorrel and gentian could affect how those drugs work.

Always mention this product when filling any prescription.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sinupret Kids Syrup Sinus & Immune, straight from the product label.

Brand Bioforce
Barcode (UPC) 897618000221
Net contents 3.38 fl. Oz.; 100 mL
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 26279
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sinupret Kids Syrup Sinus & Immune by Bioforce, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 tsp
Maximum serving Sizes:
1.5 tsp
Servings per container
14
UPC/BARCODE
897618000221
IngredientAmount% DV
Calories15 {Calories}--
Total Carbohydrates4.2 Gram(s)1%
Sugar Alcohol4.2 Gram(s)--
Gentian0 Not Present--
European Elder0 Not Present--
Sinupret(R) proprietary blend880 mg--
Cowslip0 Not Present--
Sorrel0 Not Present--
European Vervain0 Not Present--

Other ingredients: Water, Maltitol, ethyl alcohol, Cherry flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

FOR AGES 2 AND UP

Contains 0.56 ml ethyl alcohol per serving.

General Statements

Safe Natural Clinically studied

Promotes Nasal Health Supports Immune System

Product of Germany

Seals/Symbols

heart safe stimulant free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Dosage Range Age Dosage in ml Children 2-5 years: 1/2 teaspoon (2.1 ml) Children 6-11 years: 3/4 teaspoon (3.5 ml) Adults and Children age 12 and over: 1 1/2 teaspoons (7.0 ml)

3 times/day (Unless otherwise directed). Measuring cup included.

Precautions

Cautions: Do not take Sinupret(R) Kids Syrup if you are hypersensitive to one of the active ingredients or to any other ingredient of the product.

Use only with adult supervision.

Storage

Store in a dry cool place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Heart-safe - does not contain stimulants, caffeine.

Gluten-free.

Brand IP Statement(s)

BIONORICA(R) The phytolution company

Sinupret(R), Bionorica(R) The phytolution company, phytoland kids(TM) are trademarks of BIONORICA SE used under License.

General

GB 1598907 US

See for yourself

Sinupret Kids Syrup Sinus & Immune by Bioforce label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sinupret Kids Syrup Sinus & Immune by Bioforce

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.5 tsp Dosage formLiquid Servings per container14 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sinupret(R) proprietary blend

880 mg per serving

Other (inactive) ingredients: Water, Maltitol, Ethyl alcohol, Cherry flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sinupret Kids Syrup Sinus & Immune by Bioforce Drug Interactions

Want to check YOUR meds against Sinupret Kids Syrup Sinus & Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
333Drugs
333 Moderate

Ingredients driving the most interactions

Gentian 172
Sorrel 169

Each ingredient & the kinds of drugs it affects

For each ingredient in Sinupret Kids Syrup Sinus & Immune with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gentian1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.
In vitro research shows that gentian can cause vasodilation and lower blood pressure.

Likelihood Possible Evidence D

Sorrel3 drug types · 169 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Fexofenadine (Allegra)

Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).

Likelihood Likely Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sinupret Kids Syrup Sinus & Immune, from the product label.

Bioforce

See all Bioforce products
Name
Bioforce USA
Street Address
6 Grandinetti Drive
City
Ghent
State
New York
ZipCode
12075
Phone Number
1 (800) 264-2325
Pharmacist Counseling Corner

Sinupret Kids Syrup Sinus & Immune by Bioforce: Common Questions

Does Sinupret Kids Syrup Sinus & Immune by Bioforce interact with any medications?
Yes. Based on its ingredients, Sinupret Kids Syrup Sinus & Immune has a known interaction with 333 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sinupret Kids Syrup Sinus & Immune contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe for my child if she's pregnant or breastfeeding?
This product is labeled for kids, so pregnancy isn't the main concern — but if a breastfeeding parent were to take it, gentian and cowslip should be avoided due to insufficient safety data. Sorrel is rated possibly safe during breastfeeding, but concentrated medicinal doses haven't been proven safe, so it's best to avoid it. Talk with your pediatrician or pharmacist about what's right for your situation.
What does cowslip do in this formula?
Cowslip is included for its possible effectiveness in sinusitis. It's traditionally been used in herbal preparations for sinus support, though the solid clinical evidence is limited. It's one of the better-studied ingredients in this blend.
Can this syrup upset my child's stomach?
It's possible. Gentian can cause gastrointestinal upset in some children, and people using gentian with other herbs have reported nausea, vomiting, diarrhea, and bloating. Sorrel has also been linked to nausea and an unpleasant aftertaste when used with other herbs. If your child develops stomach discomfort, stop the product and call your pharmacist.
Will this work for my child's sinus infection?
Cowslip is rated possibly effective for sinusitis, meaning there's some research and traditional use backing it — but the evidence isn't strong or complete. The other ingredients haven't been studied enough to know how well they work for sinus problems. This product may help, but it's not guaranteed, and it shouldn't replace medical treatment if your child's infection is severe.
Does this syrup contain any allergens I should know about?
Sorrel pollen can trigger allergic reactions in people sensitive to weed pollen — up to 19% of people with weed allergies may react. Cowslip can also cause allergic reactions in some people. If your child has known weed or plant allergies, mention those to your pharmacist before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sinupret Kids Syrup Sinus & Immune is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sinupret Kids Syrup Sinus & Immune label
Sources

Sources & How We Checked

Sinupret Kids Syrup Sinus & Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gentian 5 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Uncini Manganelli RE, Chericoni S, Baragatti B. Ethnopharmacobotany in Tuscany: plants used as antihypertensives. Fitoterapia 2000;71:S95-100. PubMed
  4. Baragatti B, Calderone V, Testai L, et al. Vasodilator activity of crude methanolic extract of Gentiana kokiana Perr. et Song. (Gentianaceae). J Ethnopharmacol 2002;79:369-72. PubMed
  5. Sanatani M, Younus J, Stitt L, et al. Tolerability of the combination of ginger (Zingiber officinalis), gentian (Gentiana lutea) and turmeric (Curcuma longa) in patients with cancer-associated anorexia. J Complement Integr Med. 2015;12(1):57-60.

See these in context on the Gentian monograph →

Cowslip 3 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Peric A, Kovacevic SV, Gacesa D, Peric AV. Efficacy and safety of combined treatment of acute rhinosinusitis by herbal medicinal product Sinupret and mometasone furoate nasal spray. ENT Updates 2017;7(2):68-74. DOI

See these in context on the Cowslip monograph →

Sorrel 8 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
  4. Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
  5. Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
  6. Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
  7. Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
  8. Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed

See these in context on the Sorrel monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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