Major interaction on record — check this product against your medications before combining. Based on 6 of 15 ingredients. Check your meds →
Dietary supplement

Sinus Pain Ingredients & Drug Interactions

by BIOVEA Homeopathics

Sinus Pain label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sinus Pain against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Sinus Pain is a dietary supplement by BIOVEA Homeopathics with 15 active ingredients. Its ingredients are commonly taken for homeopathic digestive complaints, traditional remedy for inflammatory conditions, prescription use in certain leukemias (medical, not supplement).Based on those ingredients, 1,133 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Echinacea, Asafoetida, Arsenicum iod. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Sinus Pain by BIOVEA Homeopathics

Ask about any prescription or over-the-counter medication and we check it for interactions with Sinus Pain by BIOVEA Homeopathics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sinus Pain by BIOVEA Homeopathics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 15 active ingredients.

BIOVEA Homeopathics Sinus Pain contains 15 active ingredients, most of them traditional homeopathic substances. The ones we could verify include arsenicum iod (arsenic), asafoetida (a plant resin with a strong odor), echinacea (purple coneflower), eupatorium perf (boneset), and silicea (silicon).

The others — antimon tart, euphorbia pil, hepar sulph calc, kali bic, kreosotum, lachesis, merc iod rub, pyrogenium, and teucrium mar — are also homeopathic remedies with limited modern clinical data. The liquid comes with two inactive ingredients: organic alcohol and purified water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: temporary relief of sinus congestion and headache.
  • We looked for evidence on: Common Cold, Influenza, Upper respiratory tract infection (URTI), Migraine headache, Sinusitis, Nasal congestion — and 1 related terms.
  • The closest evidence on file: Boneset is rated "Insufficient Reliable Evidence To Rate" for Common Cold (Natural Medicines).
  • Also on file: Wild Indigo is rated "Insufficient Reliable Evidence To Rate" for Common cold.
  • Also on file: Echinacea is rated "Insufficient Reliable Evidence To Rate" for Migraine headache, Upper respiratory tract infection (URTI), Influenza.

The evidence on these ingredients is sparse. Silicea (silicon) is possibly effective for osteoporosis, though long-term safety at supplement doses hasn't been thoroughly studied.

For the other ingredients in this formula — echinacea, boneset, baptisia, asafoetida, and the rest — the data we hold doesn't establish effectiveness for sinus pain or any other condition listed in our database.

The evidence, ingredient by ingredient Arsenic Asafoetida Wild Indigo Echinacea Boneset Silicon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of the ingredients here are generally well tolerated in typical doses, but there are some real concerns. Arsenicum iod contains inorganic arsenic, a known poison and carcinogen, and the safety data advises against taking it as a supplement.

Arsenic can harm a developing baby and pass into breast milk, so it should be avoided during pregnancy and breastfeeding. Echinacea is usually well tolerated short-term but can cause allergic reactions — especially if you're sensitive to ragweed — and rare cases of liver inflammation have been reported.

Boneset may cause nausea, diarrhea, and vomiting, and contains potentially liver-toxic alkaloids; it should be avoided during pregnancy and breastfeeding. Asafoetida and baptisia (wild indigo) appear generally well tolerated at food doses, but large doses of wild indigo are poisonous and can cause vomiting and gastrointestinal complaints.

Asafoetida at medicinal doses is not well studied in pregnancy or breastfeeding.

Side effects, ingredient by ingredient Arsenic Asafoetida Wild Indigo Echinacea Boneset Silicon

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Asafoetida, Boneset, Echinacea, Arsenic.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; heart-rhythm medications.
  • For scale: 1,134 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take BIOVEA Homeopathics Sinus Pain, check with your pharmacist if you're on QT-prolonging drugs (Major), blood thinners or antiplatelet drugs (Moderate), blood pressure medications (Moderate), drugs metabolized by liver enzymes including caffeine and certain HIV or cancer medications (Moderate), or immunosuppressants (Moderate). The arsenicum iod and echinacea in this formula are the main contributors to these interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This is a traditional homeopathic formula with several ingredients that carry documented interactions with medications, most notably echinacea and asafoetida. The product also contains arsenicum iod (arsenic), which safety data advises against taking as a supplement and which must be avoided during pregnancy and breastfeeding.

If you're pregnant, breastfeeding, or taking any prescription or over-the-counter medications — especially blood thinners, blood pressure drugs, caffeine, cancer drugs, or immunosuppressants — talk with your pharmacist before starting this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sinus Pain, straight from the product label.

Brand BIOVEA Homeopathics
Barcode (UPC) 818423024936
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 249251
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sinus Pain by BIOVEA Homeopathics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Spray(s)
Maximum serving Sizes:
2 Spray(s)
UPC/BARCODE
818423024936
IngredientAmount% DV
Antimon Tart0 NP--
Arsenicum iod0 NP--
Asafoetida0 NP--
Baptisia0 NP--
Echinacea0 NP--
Eupatorium perf0 NP--
Euphorbia pil0 NP--
Hepar Sulph Calc0 NP--
Kali bic0 NP--
Kreosotum0 NP--
Lachesis0 NP--
Merc iod rub0 NP--
Pyrogenium0 NP--
Silicea0 NP--
Teucrium mar0 NP--

Other ingredients: organic Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Indications: Fast-acting homeopathic oral spray for the temporary relief of symptoms associated with sinus congestion and sinus headache.

Homeopathic

Suggested/Recommended/Usage/Directions

Directions: Adults & children over 12. Spray twice under the tongue 3 times per day. For severe symptoms, dosage may be taken up to six times the first day. Children 12 & under. Consult a doctor prior to use.

Precautions

Children 12 & under. Consult a doctor prior to use.

Warnings: If symptoms persist, consult a doctor.

If pregnant or breast feeding, ask a doctor before use.

Keep out of reach of children.

In case of accidental overdose, get medical help or call a Poison Control Center right away. Do not use if tamper evident seal is broken or missing.

General

NDC# 69607-0013-1

Formula

20% organic alcohol

General Statements

Natural relief

FDA Disclaimer Statement

These statements are based upon traditional homeopathic practice. They have not been reviewed by the Food and Drug Administration.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sinus Pain by BIOVEA Homeopathics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sinus Pain label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sinus Pain by BIOVEA Homeopathics

These are the 15 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Spray(s) Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Antimon Tart

0 NP per serving

Arsenicum iod

Interacts with
161 drugs
0 NP per serving

Arsenic is a naturally occurring element that is toxic in its inorganic form, and it is not a supplement you should take to improve your health. While...

Arsenicum iod monograph & interactions

Asafoetida

Interacts with
289 drugs
0 NP per serving

Asafoetida is a strong-smelling plant resin used widely as a spice and in traditional medicine, mainly for digestive complaints. Solid human evidence...

Asafoetida monograph & interactions

Baptisia

No known
interactions
0 NP per serving

Wild Indigo (Baptisia tinctoria) is a traditional herb most often used in combination products for colds and immune support, but high-quality human ev...

Baptisia monograph & interactions

Echinacea

Interacts with
816 drugs
0 NP per serving

Echinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears small at bes...

Echinacea monograph & interactions

Eupatorium perf

Interacts with
87 drugs
0 NP per serving

Boneset is a traditional North American herb long used in teas for fevers, colds, and flu, but modern human studies are very limited. It contains comp...

Eupatorium perf monograph & interactions

Euphorbia pil

0 NP per serving

Hepar Sulph Calc

0 NP per serving

Kali bic

0 NP per serving

Kreosotum

0 NP per serving

Lachesis

0 NP per serving

Merc iod rub

0 NP per serving

Pyrogenium

0 NP per serving

Silicea

No known
interactions
0 NP per serving

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...

Silicea monograph & interactions

Teucrium mar

0 NP per serving

Other (inactive) ingredients: Organic Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sinus Pain by BIOVEA Homeopathics Drug Interactions

Want to check YOUR meds against Sinus Pain?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,133Drugs
161 Major 971 Moderate 1 Minor

Ingredients driving the most interactions

Echinacea 816
Asafoetida 289
Arsenicum iod 161
Eupatorium perf 87

Individual Drug Interactions

The ingredients in Sinus Pain interact with 1,133 drugs. Click any drug to see the details.

4 of the 15 ingredients in Sinus Pain interact with drugs. Each result below shows which ingredient is responsible. Echinacea Asafoetida Arsenicum iod Eupatorium perf

Each ingredient & the kinds of drugs it affects

For each ingredient in Sinus Pain with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Echinacea12 drug types · 816 drugs

Caffeine

Echinacea can increase plasma levels of caffeine by inhibiting its metabolism.
Echinacea seems to increase plasma concentrations of caffeine by around 30%. This is likely due to inhibition of cytochrome P450 1A2 (CYP1A2) by echinacea.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Echinacea might inhibit the metabolism of CYP1A2 and increase plasma levels of some drugs.
Echinacea appears to inhibit CYP1A2 enzymes in humans. Additionally, echinacea seems to increase plasma concentrations of caffeine, a CYP1A2 substrate, by around 30%. Theoretically, echinacea might increase levels of other drugs metabolized by CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Echinacea may induce hepatic CYP3A4 and inhibit intestinal CYP3A4. This may increase or decrease levels of drugs metabolized by CYP3A4.
Several clinical trials have shown that taking echinacea for up to one month does not significantly affect the metabolism of various CYP3A4 substrates, including midazolam, docetaxel, etravirine, lopinavir-ritonavir, and darunavir-ritonavir. However, other clinical research shows that echinacea may increase the clearance of midazolam, suggesting that echinacea might induce CYP3A4. The discrepancy is thought to be due to differing effects of echinacea on intestinal versus hepatic CYP3A4 enzymes. Echinacea appears to induce hepatic CYP3A4 but inhibit intestinal CYP3A4. In some cases, these effects might cancel each other out, but in others, drug levels may be increased or decreased depending on the level of effect at hepatic and intestinal sites. The effect of echinacea on CYP3A4 activity may differ depending on the CYP3A4 substrate.

Likelihood Possible Evidence B
Etoposide (Vepesid)

Echinacea may increase levels of etoposide.
In one report, concomitant use of etoposide and echinacea was associated with more severe thrombocytopenia than the use of etoposide alone, suggesting inhibition of etoposide metabolism. Etoposide is a cytochrome P450 3A4 (CYP3A4) substrate. Echinacea has variable effects on CYP3A4, but some studies have reported inhibition of the enzyme.

Likelihood Possible Evidence D
Immunosuppressants

Echinacea has immunostimulant activity which may interfere with immunosuppressant therapy.
Theoretically, echinacea may interfere with immunosuppressant therapy because of its immunostimulant activity.

Likelihood Possible Evidence B
Darunavir (Prezista)

Theoretically, echinacea may interfere with the metabolism of darunavir; however, a small clinical study found no effect.
Darunavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but administration of an E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg four times daily for 14 days did not affect darunavir/ritonavir pharmacokinetics in 15 HIV-infected patients.

Likelihood Unlikely Evidence B
Dayquil Severe

Echinacea is reported to have varying effects on a number of Cytochrome P450 metabolizing enzymes in the liver, including CYP1A2 and CYP3A4, which play a role in acetaminophen and dextromethorphan metabolism (both contained in DayQuil Severe), respectively. Studies have reported both enzyme inhibition and induction, making it difficult to predict clinically significant drug interactions with reliability. Specific drug interaction studies reporting definitive results are rare, and potential drug interactions involving echinacea should likely be taken on a case-by-case basis. Based on what we know about how acetaminophen and dextromethorphan are metabolized, the risk of a clinically significant interaction between echinacea and DayQuil Severe is low.

Likelihood Unlikely Evidence A
Docetaxel (Taxotere)

Theoretically, echinacea may interfere with the metabolism of docetaxel; however, a small clinical study found no effect.
Docetaxel is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea whole plant extract (Echinaforce, A. Vogel Biopharma AG) 20 drops three times daily for 2 weeks did not alter the pharmacokinetics of docetaxel in one clinical study.

Likelihood Unlikely Evidence B
Etravirine (Intelence)

Theoretically, echinacea may interfere with the metabolism of etravirine; however, a small clinical study found no effect.
Etravirine is metabolized by cytochrome P450 3A4 (CYP3A4). Echinacea has variable effects on CYP3A4, but taking E. purpurea root extract (Arkocapsulas Echinacea, Arkopharma) 500 mg three times daily for 14 days did not alter the pharmacokinetics of etravirine in HIV-infected patients.

Likelihood Unlikely Evidence B
Lopinavir/Ritonavir (Kaletra)

Theoretically, echinacea may interfere with the metabolism of lopinavir; however, a small clinical study found no effect.
Lopinavir is metabolized by cytochrome P450 3A4 (CYP3A4) and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Echinacea has variable effects on CYP3A4, but taking E. purpurea (Echinamide, Natural Factors Nutritional Products, Inc.) 500 mg three times daily for 14 days did not alter the pharmacokinetics of lopinavir/ritonavir in healthy volunteers.

Likelihood Unlikely Evidence B
Midazolam (Versed)

Theoretically, echinacea may increase the metabolism of intravenous midazolam.
Echinacea induces hepatic CYP3A4 and might decrease plasma levels of midazolam by about 20%, reducing the effectiveness of intravenous midazolam. Echinacea also appears to inhibit intestinal CYP3A4, which could theoretically increase the bioavailability of oral midazolam. This may cancel out the decrease in availability caused by induction of hepatic CYP3A4, such that overall plasma levels after oral administration of midazolam are not affected by echinacea.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Echinacea seems to increase the clearance of warfarin, although the effect may not be clinically significant.
Preliminary clinical research in healthy male volunteers suggests that taking echinacea increases the clearance of the active S-isomer of warfarin after a single dose of warfarin, but there was not a clinically significant effect on the INR.

Likelihood Possible Evidence B
Echinacea full monograph & interactions

Asafoetida2 drug types · 289 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, asafoetida might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs. Some anticoagulant/antiplatelet drugs include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Evidence from animal research suggests that asafoetida has hypotensive effects. Theoretically, concomitant use may increase therapeutic effects of antihypertensive therapy due to hypotensive activity of asafoetida. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Asafoetida full monograph & interactions

Arsenicum iod1 drug type · 161 drugs

Qt Interval-Prolonging Drugs

Arsenic trioxide can prolong the QT interval.
Up to 40% of patients treated with prescription arsenic trioxide have a prolonged QT interval on their electrocardiogram (ECG). Theoretically, non-prescription arsenic could have an additive effect when combined with drugs that prolong the QT interval.

Likelihood Probable Evidence B
Arsenicum iod full monograph & interactions

Eupatorium perf1 drug type · 87 drugs

Cytochrome P450 3A4 (Cyp3A4) Inducers

Boneset belongs to the genus Eupatorium, and many species of this genus contain hepatotoxic pyrrolizidine alkaloids (PAs). Hepatotoxic PAs are substrates of cytochrome P450 3A4 (CYP3A4). Theoretically, drugs that induce CYP3A4 might increase the conversion of PAs to toxic metabolites. Some drugs that induce CYP3A4 include carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), and others.

Likelihood Possible Evidence D
Eupatorium perf full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sinus Pain, from the product label.

BIOVEA Homeopathics

See all BIOVEA Homeopathics products
Name
BIOVEA
Street Address
7702 E. Doubletree Ranch Rd. Suite 300, #307
City
Scottsdale
State
AZ
ZipCode
85258
Phone Number
1-800-961-4750
Web Address
www.biovea.com
Pharmacist Counseling Corner

Sinus Pain by BIOVEA Homeopathics: Common Questions

Does Sinus Pain by BIOVEA Homeopathics interact with any medications?
Yes. Based on its ingredients, Sinus Pain has a known interaction with 1,133 medications, including 161 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sinus Pain contains 15 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy?
No. Arsenicum iod (arsenic) can harm a developing baby and should be avoided during pregnancy. Boneset is also possibly unsafe during pregnancy due to potential toxicity and lack of safety data. Asafoetida and echinacea have limited safety data in pregnancy. Talk with your doctor or pharmacist for personalized advice.
Is this safe while breastfeeding?
No. Arsenic can pass to your baby in breast milk and should be avoided. Boneset should also be avoided because harmful alkaloids may pass to the infant and safety hasn't been established. Asafoetida and echinacea lack adequate safety data for breastfeeding, so talk with your pharmacist.
What's echinacea doing in this sinus formula?
Echinacea (purple coneflower) is traditionally used to support immune function and upper respiratory health, though the evidence for it in sinus pain specifically isn't established in our data.
Can this product raise my caffeine sensitivity?
Yes. Echinacea in this formula may inhibit how your body breaks down caffeine, increasing caffeine levels by around 30%. If you're sensitive to caffeine or drink coffee regularly, be aware you might feel more of its effects.
Why does this liquid contain alcohol?
Organic alcohol is used as a solvent and preservative in homeopathic liquids to keep the plant extracts stable and prevent spoilage.
What is silicea and why is it here?
Silicea is silicon, a mineral possibly effective for osteoporosis. It's included here as a traditional homeopathic ingredient, though its role in sinus pain is unclear from the evidence we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sinus Pain label
Go deeper

The Full Monographs Behind Sinus Pain’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Arsenic

Interacts with 161 drugs

Arsenic is a naturally occurring element that is toxic in its inorganic form, and it is not a supplement you should take to improve your health. While arsenic trioxide is a real, doctor-pres...

Read the full Arsenic monograph → Herb & supplement monograph

Asafoetida

Interacts with 289 drugs

Asafoetida is a strong-smelling plant resin used widely as a spice and in traditional medicine, mainly for digestive complaints. Solid human evidence for its medicinal benefits is limited, t...

Read the full Asafoetida monograph → Herb & supplement monograph

Wild Indigo

Wild Indigo (Baptisia tinctoria) is a traditional herb most often used in combination products for colds and immune support, but high-quality human evidence is very limited. It can be toxic...

Read the full Wild Indigo monograph → Herb & supplement monograph

Echinacea

Interacts with 816 drugs

Echinacea is a popular herb taken to help prevent or shorten the common cold, but study results are mixed and the overall benefit appears small at best. It is generally well tolerated for sh...

Read the full Echinacea monograph → Herb & supplement monograph

Boneset

Interacts with 87 drugs

Boneset is a traditional North American herb long used in teas for fevers, colds, and flu, but modern human studies are very limited. It contains compounds (pyrrolizidine alkaloids) that may...

Read the full Boneset monograph → Herb & supplement monograph

Silicon

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for hair, skin, nail, and bone health. Some s...

Read the full Silicon monograph →
Sources

Sources & How We Checked

Sinus Pain's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 117 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Arsenic 35 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  4. Uthus EO, Seaborn CD. Deliberations and evaluations of the approaches, endpoints and paradigms for dietary recommendations of the other trace elements. J Nutr 1996;126:2452s-2459s. PubMed
  5. Nielsen FH. Nutritional requirements for boron, silicon, vanadium, nickel, and arsenic: current knowledge and speculation. FASEB J 1991;5:2661-7. DOI
  6. US Department of Health and Human Services. Agency for Toxic Substances and Disease Registry. Public Health Statement: Arsenic. August 2007. Available at: www.atsdr.cdc.gov/toxprofiles/tp2-c1-b.pdf (Accessed 14 April 2008).
  7. Eckhert CD. Other trace elements. In: Shils ME, Shike M, Ross AC, et al (eds). Modern Nutrition in Health and Disease. 10th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2006.
  8. Ratnaike RN. Acute and chronic arsenic toxicity. Postgrad Med J 2003;79:391-6. PubMed
  9. Wasserman GA, Liu X, Parvez F, et al. Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect 2004;112:1329-33. PubMed
  10. Lamm SH, Ferdosi H, Dissen EK, Li J, Ahn J. A systematic review and meta-regression analysis of lung cancer risk and inorganic arsenic in drinking water. Int J Environ Res Public Health 2015;12(12):15498-515. PubMed
  11. Hsueh YM, Chen WJ, Lee CY, et al. Association of arsenic methylation capacity with developmental delays and health status in children: a prospective case-control trial. Sci Rep 2016;6:37287. PubMed
  12. Moon KA, Oberoi S, Barchowsky A, et al. A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease. Int J Epidemiol 2017;46(6):1924-39. PubMed
  13. Dong J, Su SY. The association between arsenic and children's intelligence: a meta-analysis. Biol Trace Elem Res 2009;129(1-3):88-93. PubMed
  14. Nong Q, Zhang Y, Guallar E, Zhong Q. Arsenic exposure and predicted 10-year atherosclerotic cardiovascular risk using the pooled cohort equations in U.S. hypertensive adults. Int J Environ Res Public Health 2016;13(11). pii: E1093. PubMed
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Silicon 19 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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