Sodium R-Lipoate 600 mg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking Sodium R-Lipoate 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sodium R-Lipoate 600 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 205 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium R-Lipoate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sodium R-Lipoate 600 mg by SuperSmart
Ask about any prescription or over-the-counter medication and we check it for interactions with Sodium R-Lipoate 600 mg by SuperSmart — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sodium R-Lipoate 600 mg by SuperSmart
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: sodium R-lipoate, a form of the compound lipoic acid. It's provided as 600 mg per tablet or pill.
The inactive ingredients are microcrystalline cellulose, stearic acid, bamboo extract, and tricalcium phosphate.
Does it work?
Couldn't assess
The data we hold shows sodium R-lipoate is likely effective for cystic fibrosis and possibly effective for reducing kidney damage from the medication amphotericin B. For bipolar disorder and congestive heart failure, the evidence isn't established enough in our data to rate it either way.
How safe is it?
Well-documented data
Sodium is essential in small amounts, but too much is linked to high blood pressure and heart strain. The product itself is well tolerated when used in moderation at intakes up to the recommended daily limit.
Serious side effects from excess sodium are rare but can include worsened cardiovascular disease, high blood pressure, and kidney disease. The caution here is straightforward: normal dietary sodium is fine, but don't add sodium supplements or take very high doses without talking to your doctor first.
Population studies have also linked high sodium intake to increased gastric cancer risk over time.
Meds to double-check
Moderate interaction found
Double-check this product with your pharmacist if you take blood pressure medication (antihypertensives), lithium, corticosteroids, didanosine, sodium phosphate bowel prep, tolvaptan, or any other medication that contains sodium. All these carry moderate-severity interactions with added sodium.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This supplement is worth considering if you have cystic fibrosis or need help with amphotericin B side effects — but only under medical guidance. If you take blood pressure medication, lithium, corticosteroids, or any other sodium-retaining drug, check with your pharmacist before starting.
High sodium intake can interfere with how these drugs work and raise your risk of serious electrolyte problems.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sodium R-Lipoate 600 mg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Barcode (UPC) | 5453003825197 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 315633 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sodium R-Lipoate 600 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Sodium R-Lipoate | 600 mg | -- |
Other ingredients: Microcrystalline Cellulose, Stearic Acid, Bamboo Extract, Tricalcium Phosphate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Antioxidant Supplement
Sodium R-Lipoate 600 mg per day Each tablet contains 300 mg sodium R-lipoate.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommended Use: Adults. Take 1 to 2 tablets a day.
Precautions
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sodium R-Lipoate 600 mg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sodium R-Lipoate 600 mg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Sodium R-Lipoate
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium R-Lipoate monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Bamboo Extract, Tricalcium Phosphate. These complete the product’s ingredient list but are not active constituents.
Sodium R-Lipoate 600 mg by SuperSmart Drug Interactions
HelloPharmacist Interaction Report
Sodium R-Lipoate 600 mg by SuperSmart is a single-ingredient supplement, and sodium does interact with several medication types.
The most serious concern is with blood pressure drugs (antihypertensives): high sodium intake can blunt their effect and may force you to need higher doses to control your pressure.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to watch for interactions with lithium, a mood stabilizer — sodium changes how much lithium your body holds onto, and too much sodium can drop your lithium levels while too little can push them dangerously high. If you take lithium, your dose may need adjustment.
Corticosteroids, didanosine (an HIV medication), sodium phosphate bowel prep, tolvaptan (for low sodium levels), and other sodium-containing drugs all carry a moderate risk of high blood sodium (hypernatremia) when combined with this supplement.
Altogether, these interactions span 203 individual medications. Run your exact prescriptions through the checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sodium R-Lipoate 600 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sodium R-Lipoate 600 mg interact with 205 drugs. Click any drug to see the details.
1 of the 1 ingredient in Sodium R-Lipoate 600 mg interact with drugs. Each result below shows which ingredient is responsible. Sodium R-Lipoate
AcebutololRhotral, Sectral
How Acebutolol interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Atenolol, Chlorthalidone interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium R-lipoate + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Azilsartan, Chlorthalidone interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium R-lipoate + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium R-lipoate + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium R-lipoate + Beclomethasone Dipropionate interactionBenazeprilLotensin
How Benazepril interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium R-lipoate + Benzthiazide interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Sodium R-Lipoate 600 mg — through 1 ingredient. Tap an ingredient for the detail:
Sodium R-lipoateCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium R-lipoate + Betamethasone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sodium R-Lipoate 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Sodium R-Lipoate
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Sodium R-Lipoate 600 mg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, LDA
- Street Address
- Avenida Do Infante 66 Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
Sodium R-Lipoate 600 mg by SuperSmart: Common Questions
Does Sodium R-Lipoate 600 mg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe if I have high blood pressure?
Can I take this if I'm on lithium?
What is sodium R-lipoate used for?
Is it safe in pregnancy or while breastfeeding?
What are the main side effects?
Can I take this with corticosteroid medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sodium R-Lipoate 600 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sodium R-Lipoate 600 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sodium R-Lipoate 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
- Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
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