Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Stabilize Ingredients & Drug Interactions

by Arms Race Nutrition

Stabilize label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stabilize against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Stabilize is a dietary supplement by Arms Race Nutrition with 4 active ingredients. Its ingredients are commonly taken for estrogen/hormone balance, acne and hormonal skin issues, prostate health support.Based on those ingredients, 1,467 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Shoden Ashwagandha extract, Berberine HCl, 3,3'-Diindolylmethane. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Stabilize by Arms Race Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Stabilize by Arms Race Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Stabilize by Arms Race Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Stabilize contains 4 active ingredients. The main ones are berberine HCl (a plant alkaloid with potential effects on metabolism and blood sugar), 3,3'-diindolylmethane or DIM (a compound from cruciferous vegetables), Shoden ashwagandha extract (a traditional herb used for stress and sleep), and Lepidamax gelatinized maca root powder (a plant root traditionally used as a food supplement).

The capsule itself is made of cellulose, with magnesium stearate and silicon dioxide as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support healthy hormone levels.
  • We looked for evidence on: Age-related testosterone deficiency, Amenorrhea, Androgenic alopecia, Antidepressant-induced sexual dysfunction, Antipsychotic-induced metabolic side effects, Anxiety — and 4 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Amenorrhea, Antidepressant-induced sexual dysfunction, Athletic performance, Chronic fatigue syndrome (CFS), and more.

The evidence for what Stabilize does is limited. Berberine shows possibly effective evidence for high cholesterol, PCOS, H. pylori infection, high blood pressure, and diabetes.

Ashwagandha shows possibly effective evidence for insomnia, anxiety, stress, and generalized anxiety disorder. Diindolylmethane and maca, however, have insufficient evidence in our data to rate them for any condition—the research either isn't there yet or isn't strong enough to draw conclusions.

The evidence, ingredient by ingredient Diindolylmethane Berberine Ashwagandha Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Berberine and ashwagandha are generally well tolerated in the short term, but long-term safety data for diindolylmethane is not well established. Common side effects across these ingredients include digestive upset (nausea, vomiting, diarrhea, gas), headache, and rash.

Berberine may cause dizziness, drowsiness, and fatigue. Ashwagandha has rare reports of liver damage and intracranial bleeding linked to it.

Maca is generally well tolerated as a food but may cause stomach pain if consumed raw. For pregnancy: diindolylmethane safety data advises against use due to possible hormone effects.

Berberine should be avoided in pregnancy (possible harm to newborns) and while breastfeeding (passes into milk). Ashwagandha is traditionally thought to risk miscarriage and should be avoided in pregnancy, and there isn't enough data to breastfeed safely.

Maca data doesn't exist in our files—talk with your pharmacist or doctor for personalized advice.

Side effects, ingredient by ingredient Diindolylmethane Berberine Ashwagandha Maca

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Ashwagandha, Diindolylmethane, Berberine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,468 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Stabilize, check your medications in the tool below, especially: cyclosporine (Major interaction with berberine), blood pressure medications (Moderate with berberine and ashwagandha), blood thinners and antiplatelet drugs (Moderate with berberine), diabetes medications (Moderate with berberine and ashwagandha), CNS depressants and benzodiazepines (Moderate with berberine and ashwagandha), thyroid hormones (Moderate with ashwagandha), immunosuppressants (Moderate with ashwagandha), and any drugs metabolized by CYP3A4, CYP2D6, CYP2C9, or CYP1A2 enzymes (Moderate or Minor with multiple ingredients).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Stabilize is a four-ingredient supplement with documented interactions affecting over 1,400 medications, especially serious ones with cyclosporine and many others affecting your blood pressure, blood sugar, and sedation. If you take any regular medications—particularly blood pressure drugs, diabetes drugs, blood thinners, immunosuppressants, or sedatives—check them against this product before you start.

Pregnant or breastfeeding? Skip berberine and ashwagandha entirely; talk with your pharmacist about the others.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stabilize, straight from the product label.

Brand Arms Race Nutrition
Barcode (UPC) 672975063221
Net contents 140 Vegetable Cap(s)
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241241
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stabilize by Arms Race Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Capsule(s)
Maximum serving Sizes:
5 Capsule(s)
Servings per container
28
UPC/BARCODE
672975063221
IngredientAmount% DV
3,3'-Diindolylmethane200 mg--
Berberine HCl1200 mg--
Shoden Ashwagandha extract120 mg--
Lepidamax Gelatinized Maca root powder2100 mg--

Other ingredients: Cellulose Capsule, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stabilize is the perfect formula to help balance, support, and sustain healthy hormone levels. Scientifically-formulated to address hormonal health, Stabilize's key ingredients have been shown to assist in the maintenance of healthy levels of critical hormones and weight management.

Hormone health supplement Boost Support Balance Libido

Manufactured in a U.S. cGMP facility.

Precautions

Warning: this product is only intended for use in healthy adults 18 years of age or older.

Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

Discontinue use and consult your health care professional if you experience adverse reaction to this product. Discontinue use 2 weeks prior to surgery. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Consume three capsules at morning meal and two capsules at afternoon meal.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA

General Statements

Old school dedication. Modern science.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Shoden is a registered trademark of Arjuna Natural Pvt. Ltd. Lepidamax and its associated logo are registered trademarks of Nutrition 21, LLC. Lepidamax is patent protected.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stabilize by Arms Race Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stabilize label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stabilize by Arms Race Nutrition

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Capsule(s) Dosage formCapsule Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

3,3'-Diindolylmethane

Interacts with
269 drugs
200 mg per serving

Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone balance and...

3,3'-Diindolylmethane monograph & interactions

Berberine HCl

Interacts with
1,160 drugs
1200 mg per serving

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research vari...

Berberine HCl monograph & interactions

Shoden Ashwagandha extract

Interacts with
1,372 drugs
120 mg per serving Form: Withanolide Glycosides

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Shoden Ashwagandha extract monograph & interactions

Lepidamax Gelatinized Maca root powder

No known
interactions
2100 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Lepidamax Gelatinized Maca root powder monograph & interactions

Other (inactive) ingredients: Cellulose Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stabilize by Arms Race Nutrition Drug Interactions

Want to check YOUR meds against Stabilize?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,467Drugs
1 Major 1,414 Moderate 52 Minor

Ingredients driving the most interactions

Shoden Ashwagandha extract 1,372
Berberine HCl 1,160
3,3'-Diindolylmethane 269

Individual Drug Interactions

The ingredients in Stabilize interact with 1,467 drugs. Click any drug to see the details.

3 of the 4 ingredients in Stabilize interact with drugs. Each result below shows which ingredient is responsible. Shoden Ashwagandha extract Berberine HCl 3,3'-Diindolylmethane

Each ingredient & the kinds of drugs it affects

For each ingredient in Stabilize with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Shoden Ashwagandha extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
Shoden Ashwagandha extract full monograph & interactions

Berberine HCl15 drug types · 1,160 drugs

Cyclosporine (Neoral, Sandimmune)

Berberine can increase serum levels of cyclosporine.
Berberine can reduce metabolism and increase serum levels of cyclosporine. Berberine might inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine.

Likelihood Probable Evidence A
Anticoagulant/Antiplatelet Drugs

Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, berberine might have additive effects when used with anticoagulant and antiplatelet drugs and increase the risk of bleeding.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that berberine may lower blood glucose levels. Theoretically, berberine might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, berberine might have additive effects with antihypertensive drugs.
Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, berberine might increase the sedative effects of CNS depressants.
Animal research suggests that berberine may have sedative effects. Theoretically, use of berberine along with CNS depressants might produce additive therapeutic and adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, taking berberine with drugs metabolized by CYP2C9 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, use of berberine with drugs metabolized by CYP2D6 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, use of berberine with drugs metabolized by CYP3A4 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence A
Dextromethorphan (Robitussin Dm, Others)

Theoretically, berberine may increase serum levels of dextromethorphan.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. This may increase the effects and side effects of dextromethorphan.

Likelihood Possible Evidence B
Losartan (Cozaar)

Berberine might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan.

Likelihood Possible Evidence B
Metformin (Glucophage)

Theoretically, berberine might increase the therapeutic and adverse effects of metformin.
In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin.

Likelihood Possible Evidence D
Midazolam (Versed)

Berberine can reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Berberine might increase the sedative effect of pentobarbital.
Evidence from animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, combining berberine and pentobarbital might increase the sedative effects of pentobarbital.

Likelihood Possible Evidence D
Tacrolimus (Prograf)

Berberine has been associated with increased blood levels of tacrolimus.
In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL.

Likelihood Possible Evidence D
Acetazolamide

Laboratory studies and initial clinical findings suggest that berberine has the potential to increase acetazolamide concentrations in the body. More research is needed to confirm this interaction.

Likelihood Possible Evidence C
Berberine HCl full monograph & interactions

3,3'-Diindolylmethane3 drug types · 269 drugs

Diuretic Drugs

Theoretically, diindolylmethane might increase the risk of hyponatremia if used with sodium-depleting diuretics.
Large doses of diindolylmethane (600 mg daily) have been associated with two cases of asymptomatic hyponatremia in clinical research.

Likelihood Possible Evidence B
Estrogens

Theoretically, diindolylmethane might increase or decrease the effects of estrogens.
Diindolylmethane might have mild estrogenic or antiestrogenic effects. Theoretically, large amounts of diindolylmethane might interfere with hormone replacement therapy.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, diindolylmethane might lower serum levels of CYP1A2 substrates.
In vitro evidence suggests that diindolylmethane can induce CYP1A2. Theoretically, it might increase metabolism of CYP1A2 substrates and lower serum concentrations. This interaction has not been reported in humans.

Likelihood Unlikely Evidence D
3,3'-Diindolylmethane full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stabilize, from the product label.

Arms Race Nutrition

See all Arms Race Nutrition products
Name
Arms Race Nutrition, LLC
Street Address
www.armsracenutrition.com
City
Sterling
State
VA
ZipCode
20164
Phone Number
(833) 568-4321
Web Address
www.armsracenutrition.com
Pharmacist Counseling Corner

Stabilize by Arms Race Nutrition: Common Questions

Does Stabilize by Arms Race Nutrition interact with any medications?
Yes. Based on its ingredients, Stabilize has a known interaction with 1,467 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stabilize contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Stabilize while pregnant?
No. Berberine should be avoided—it's linked to harm in newborns and may cross the placenta. Ashwagandha is traditionally thought to risk miscarriage and should be avoided. Diindolylmethane should be avoided due to possible hormone effects. There isn't enough data for maca in supplement amounts. Talk with your doctor before considering any of these ingredients.
Can I breastfeed while taking this product?
No. Berberine passes into breast milk and should be avoided. Ashwagandha doesn't have enough safety information, so avoid it. Diindolylmethane has no reliable safety data available while breastfeeding, and maca data isn't on file. Talk with your pharmacist or doctor about what's safe.
What are the most common side effects?
Digestive complaints—nausea, vomiting, diarrhea, gas, and abdominal pain—are the most common. Headache and rash can also occur. Ashwagandha and berberine may cause drowsiness or dizziness. These don't happen to everyone and tend to be mild, but they're worth knowing about.
Does this work for blood sugar or cholesterol?
Berberine shows possibly effective evidence for high cholesterol and diabetes. The other ingredients don't have established evidence in our data for either condition. If you're managing blood sugar or cholesterol, talk with your doctor—especially since berberine interacts with diabetes and blood pressure drugs.
Is this good for anxiety or sleep?
Ashwagandha in this product shows possibly effective evidence for anxiety, insomnia, stress, and generalized anxiety disorder. But if you're already taking a sedative, anxiety medication, or sleeping pill, ashwagandha might increase its effects, so check with your pharmacist first.
What's diindolylmethane, and why is it in here?
Diindolylmethane (DIM) is a compound found in cruciferous vegetables like broccoli. The supplement uses it for hormone-related conditions, but the evidence is insufficient to rate it for anything yet. It theoretically affects estrogen and can interact with water pills and some other medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stabilize label
Go deeper

The Full Monographs Behind Stabilize’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Diindolylmethane

Interacts with 269 drugs

Diindolylmethane (DIM) is a compound made when your body digests cruciferous vegetables, and it is sold as a supplement mainly for hormone balance and cancer prevention. Although early lab s...

Read the full Diindolylmethane monograph → Herb & supplement monograph

Berberine

Interacts with 1,160 drugs

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research varies and it is not a replacement for presc...

Read the full Berberine monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph →
Sources

Sources & How We Checked

Stabilize's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 88 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Diindolylmethane 14 references
  1. Natl Inst Health, Natl Inst Environmental Health Sci. Indole-3-carbinol. Available at: http://ntp-server.niehs.nih.gov.
  2. Balk JL. Indole-3-carbinol for cancer prevention. Altern Med Alert 2000; 3:105-7.
  3. Riby JE, Chang GHF, Firestone GL, Bjeldanes LF. Ligand-independent activation of estrogen receptor function by 3,3'-diindolylmethane in human breast cancer cells. Biochem Pharmacol 2000;60:167-77. PubMed
  4. Lake BG, Tredger JM, Renwick AB, et al. 3'3-diindolylmethane induces CYP1A2 in cultured precision-cut human liver slices. Xenobiotica 1998;28:803-11. PubMed
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Ashwagandha 32 references
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Maca 1 reference
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