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Dietary supplement

Standardized Herbal Extract Boswellia 250 mg Ingredients & Drug Interactions

by Puritan's Pride

Standardized Herbal Extract Boswellia 250 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Standardized Herbal Extract Boswellia 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Standardized Herbal Extract Boswellia 250 mg is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis, inflammation.Based on those ingredients, 952 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boswellia Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride

Ask about any prescription or over-the-counter medication and we check it for interactions with Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Boswellia extract, standardized to 250 mg per capsule. Boswellia (also called Indian frankincense) is a resin from the Boswellia serrata tree, traditionally used in Ayurvedic medicine.

The capsule itself is filled with inactive ingredients—cellulose, gelatin, and vegetable magnesium stearate—that help form and preserve the tablet.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Boswellia Serrata's overall clinical evidence instead.

Moderate

Some clinical evidence supports Boswellia Serrata for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Osteoarthritis — rated "Possibly Effective" (Natural Medicines).

The evidence for Boswellia is limited. It is possibly effective for osteoarthritis—some research suggests it may help ease joint pain and stiffness.

For other uses listed here—hay fever (allergic rhinitis), Alzheimer disease, asthma, and cluster headache—the evidence is not yet strong enough to rate it reliably. If you're considering this for osteoarthritis, talk with your doctor about what the research shows so far and whether it's right for you.

The evidence, ingredient by ingredient Boswellia Serrata

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, Boswellia extract is generally well tolerated in the short term, though quality and dose vary widely between brands. The most common side effects are mild: abdominal pain, diarrhea, headache, heartburn, itching, and nausea.

Dizziness and vertigo have also been reported in some people. A rare but serious concern is bezoar formation (a ball of undigested material in the stomach) if very large amounts are swallowed—this is mainly a risk if you chew and swallow large pieces of raw gum resin over time.

Pregnancy and breastfeeding: The safety data advises against use during pregnancy—not enough is known. Similarly, safety during breastfeeding is unknown, so it's best to avoid it then too.

If you're pregnant or nursing and interested in taking this, talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Boswellia Serrata

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Boswellia Serrata.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 953 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Boswellia, check with your pharmacist or doctor if you take any immunosuppressants (medications that weaken your immune system on purpose). You should also double-check any medications your liver processes, including certain antidepressants and pain relievers (CYP2D6 substrates), acid-reflux or blood-thinning drugs (CYP2C19 substrates), some caffeine-based medications (CYP1A2 substrates), warfarin or diabetes drugs (CYP2C9 substrates), and statins or blood pressure drugs (CYP3A4 substrates).

Use the interaction search tool on this page with your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Boswellia is possibly effective for osteoarthritis, though the evidence isn't strong. Because it may interact with a very large number of medications through liver-enzyme systems and potentially weaken immunosuppressants, you'll need to check your exact prescriptions with your pharmacist or doctor before taking it.

It's generally well tolerated by mouth, but should be avoided in pregnancy and while breastfeeding. Ask your healthcare provider whether this product makes sense for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Standardized Herbal Extract Boswellia 250 mg, straight from the product label.

Brand Puritan's Pride
Barcode (UPC) 0250077132263
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Aug 24, 2012
DSLD ID 12256
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
0250077132263
IngredientAmount% DV
Boswellia Extract250 mg--

Other ingredients: Cellulose, Gelatin, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

STORE IN A DRY PLACE AND AVOID EXCESSIVE HEAT.

Precautions

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

WARNING: Pregnant and lactating women should consult a doctor before using any product. Consult your doctor before use if you have, or have had, ANY HEALTH CONDITION or if you are taking ANY MEDICATIONS OR REMEDIES including OTC medications, or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18.

KEEP OUT OF REACH OF CHILDREN.

Seals/Symbols

GUARANTEED QUALITY LABORATORY TESTED

Brand IP Statement(s)

(C) 2007 Puritan's Pride, Inc.

General

B13227 03C PROD. NO. 13226

FDA Statement of Identity

Dietary Supplement

General Statements

Supports Cartilage Components for Joint Health

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) capsule three to five times daily, preferably with meals. Do not exceed recommended dose. As a reminder, discuss the supplements and medications you take with your health care providers.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Standardized Herbal Extract Boswellia 250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Boswellia Extract

Interacts with
952 drugs
250 mg per serving Form: Boswellic Acid

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoart...

Boswellia Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Gelatin, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride Drug Interactions

Want to check YOUR meds against Standardized Herbal Extract Boswellia 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
952Drugs
952 Moderate

Ingredients driving the most interactions

Boswellia Extract 952

Individual Drug Interactions

The ingredients in Standardized Herbal Extract Boswellia 250 mg interact with 952 drugs. Click any drug to see the details.

1 of the 1 ingredient in Standardized Herbal Extract Boswellia 250 mg interact with drugs. Each result below shows which ingredient is responsible. Boswellia Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Standardized Herbal Extract Boswellia 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Boswellia Extract6 drug types · 952 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP1A2 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C19 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C19 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2C9 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2C9 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Boswellia serrata might increase the levels of CYP2D6 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP2D6 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, Boswellia serrata might increase or decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Boswellia serrata gum resin inhibits CYP3A4 enzymes. Other in vitro research shows that Boswellia serrata extract inhibits CYP3A4 enzymes at most concentrations, although it may modestly induce enzyme activity at low concentrations.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Boswellia serrata might alter the effects of immunosuppressive drugs.
Some in vitro research suggests that Boswellia serrata extracts might inhibit mediators of autoimmune disorders such as leukotrienes and reduce production of antibodies and cell-mediated immunity. However, other in vitro research suggests that, when coupled with calcium ions, boswellic acids containing the keto group have immunostimulant properties within specific cell signaling pathways.

Likelihood Possible Evidence D
Boswellia Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Standardized Herbal Extract Boswellia 250 mg, from the product label.

Puritan's Pride

See all Puritan's Pride products
Name
Puritan's Pride, Inc.
City
Oakdale
State
NY
ZipCode
11769
Pharmacist Counseling Corner

Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride: Common Questions

Does Standardized Herbal Extract Boswellia 250 mg by Puritan's Pride interact with any medications?
Yes. Based on its ingredients, Standardized Herbal Extract Boswellia 250 mg has a known interaction with 952 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Standardized Herbal Extract Boswellia 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Boswellia extract, and what is it used for?
Boswellia extract comes from the resin of the Boswellia serrata tree, used for centuries in traditional Indian (Ayurvedic) medicine. It is possibly effective for osteoarthritis—some research suggests it may help with joint pain—though for other conditions like hay fever or asthma, the evidence isn't strong enough yet to rate it reliably.
Can I take this while I'm pregnant or breastfeeding?
The safety data advises against it during pregnancy—not enough is known. Safety during breastfeeding is also unknown, so it's best to avoid it then. Talk with your doctor or pharmacist about your individual situation.
What side effects might I get from taking Boswellia?
The most common side effects are mild stomach-related symptoms—abdominal pain, diarrhea, nausea, and heartburn—along with headache, heartburn, and itching. Some people also report dizziness and vertigo. A rare but serious risk is bezoar formation (a stomach blockage) if you chew and swallow very large amounts of raw gum resin.
Why do I need to check my medications before taking this?
Boswellia may interact with a large number of medications by affecting how your liver breaks them down, potentially raising drug levels in your blood and increasing side effects. It may also weaken certain immune-suppressing drugs. Use the interaction tool on this page to search your exact prescriptions, and talk with your pharmacist or doctor before starting.
How many active ingredients does this product have?
This product has one active ingredient: Boswellia extract at 250 mg. The rest of the capsule is made up of inactive ingredients (cellulose, gelatin, and vegetable magnesium stearate) that help form and preserve the tablet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Standardized Herbal Extract Boswellia 250 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Standardized Herbal Extract Boswellia 250 mg label
Go deeper

The Full Monographs Behind Standardized Herbal Extract Boswellia 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Boswellia Serrata

Interacts with 952 drugs

Boswellia serrata is a tree resin used in traditional medicine, mainly for joint pain and inflammation. Some studies suggest it may help with osteoarthritis symptoms, but the overall evidenc...

Read the full Boswellia Serrata monograph →
Sources

Sources & How We Checked

Standardized Herbal Extract Boswellia 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Boswellia Serrata 16 references
  1. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma: results of a double-blind, placebo-controlled, 6-week clinical study. Eur J Med Res 1998;3:511-4.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kimmatkar N, Thawani V, Hingorani L, et al. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine 2003;10:3-7. PubMed
  4. Liu JJ, Nilsson A, Oredsson S, et al. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93. PubMed
  5. Wildfeuer A, Neu IS, Safayhi H, et al. Effects of boswellic acids extracted from a herbal medicine on the biosynthesis of leukotrienes and the course of experimental autoimmune encephalomyelitis. Arzneimittelforschung 1998;48:668-74.
  6. Gupta I, Parihar A, Malhotra P, et al. Effects of gum resin of Boswellia serrata in patients with chronic colitis. Planta Med 2001;67:391-5. PubMed
  7. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. Arthritis Res Ther 2008;10:R85.
  8. Sengupta K, Krishnaraju AV, Vishal AA, et al. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 2010;7:366-77.
  9. Ernst E. Frankincense: systematic review. BMJ 2008;337:a2813. PubMed
  10. Kirste S, Treier M, Wehrle SJ, et al. Boswellia serratea extract acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial. Cancer 2011;117:3788-95.
  11. Frank A, Unger M. Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction. J Chromatogr A 2006;111 PubMed
  12. Altmann A, Poeckel D, Fischer L, et al. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. Br J Pharmacol 2004;141:223-32.
  13. El Fortia, M., Badi, H., Elalem, Kh, Kadiki, O., and Topov, Y. Olibanum bezoar: complication of a traditional popular medicine. East Mediterr.Health J 2006;12(6):927-929.
  14. Meshkat S, Mahmoodi Baram S, Rajaei S, et al. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury. Brain Inj 2022;36(4):553-559. PubMed
  15. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  16. Valente IVB, Garcia D, Abbott A, et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat 2024;204(3):521-530. PubMed

See these in context on the Boswellia Serrata monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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