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Dietary supplement

Super Strength Probiotic Max Ingredients & Drug Interactions

by Simply Supplements

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Strength Probiotic Max is a dietary supplement by Simply Supplements with 1 active ingredient. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LactoSpore. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Strength Probiotic Max by Simply Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “LactoSpore” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product has 1 active ingredient: Fructo-Oligosaccharides (FOS), a type of carbohydrate that acts as a prebiotic — basically food for the good bacteria in your gut. The product also contains LactoSpore, which is listed as a blend of component ingredients we don't have detailed information on here.

The inactive ingredients are bulking agents and anti-caking agents that help hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Fructo-oligosaccharides (fos)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestive and gut health support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Diarrhea, Dyspepsia, Flatulence — and 4 related terms.
  • The closest evidence on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation (Natural Medicines).
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Travelers' diarrhea.

The evidence for FOS isn't established yet in the data we hold. It's been studied for osteoporosis, constipation, diabetes, travelers' diarrhea, and high cholesterol, but we don't have reliable evidence to rate how well it works for any of those uses.

That doesn't mean it doesn't work — it means the research so far hasn't been strong enough to draw firm conclusions. Talk with us if you want to know whether this might fit what you're trying to do.

The evidence, ingredient by ingredient Bacillus Coagulans Fructo-oligosaccharides (fos)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

FOS is generally well tolerated at food amounts, but at higher supplement-level doses it can cause gas, bloating, abdominal pain, flatulence, constipation, and intestinal sounds. Good news: a review of eight small studies showed that doses ranging from 2.5 to 15 grams daily for up to 8 weeks didn't increase these symptoms compared with placebo — so for most people, symptoms tend to be mild or don't show up at typical doses.

Still, supplement-level FOS hasn't been studied extensively, so it's wise to check with your doctor before starting, especially if you have a sensitive stomach. We have no pregnancy or lactation data on file for this product.

Side effects, ingredient by ingredient Bacillus Coagulans Fructo-oligosaccharides (fos)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, bring your medication list in or use the checker below — we want to make sure this product is a good fit for what you're already taking.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This probiotic might be worth trying if you're looking to feed the good bacteria in your gut, but the evidence for specific benefits isn't solid yet. If you get bloating or gas easily, start low and go slow.

Talk with your pharmacist before starting, especially if you're pregnant, nursing, or have any digestive conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Strength Probiotic Max, straight from the product label.

Brand Simply Supplements
Barcode (UPC) 5060370564453
Net contents 0 Not Present
Market status On market
Date entered into DSLD Feb 24, 2017
DSLD ID 70742
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Strength Probiotic Max by Simply Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
UPC/BARCODE
5060370564453
IngredientAmount% DV
Fructo-Oligosaccharides100 mg--
LactoSpore0 NP--

Other ingredients: Fructo-Oligosaccharides, Bulking Agent, LactoSpore, Anti-Caking Agent

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

1 billion ‘friendly’ bacteria

Same day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class!

PriceMatch guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

Seals/Symbols

Quality Assured

V Vegetarian

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Take two tablets daily as a food supplement or as directed by a healthcare professional.

Precautions

Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Do not exceed stated dose.

Keep away from children at all times.

Do not use if seal is broken.

Pregnant or lactating women should consult a Doctor before using this product.

Storage

Store in a cool dry place.

Formulation

Suitable for Vegetarians.

Brand IP Statement(s)

LactoSpore

Formula

Product Information Probiotic Max provides the innovative ingredient LactoSpore; a spore-forming ‘friendly’ bacterium that supports the protective intestinal microflora naturally found in the gut. Each tablet provides 1 billion ‘friendly’ bacteria to promote healthy digestion.

General

E597

See for yourself

Super Strength Probiotic Max by Simply Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Strength Probiotic Max by Simply Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

LactoSpore

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

LactoSpore monograph & interactions

Other (inactive) ingredients: Fructo-Oligosaccharides, Bulking Agent, LactoSpore, Anti-Caking Agent. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Strength Probiotic Max by Simply Supplements Drug Interactions

Want to check YOUR meds against Super Strength Probiotic Max?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Strength Probiotic Max with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

LactoSpore1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Super Strength Probiotic Max, from the product label.

Simply Supplements

See all Simply Supplements products
Name
Simply Supplements
Street Address
PO Box 1330
City
Peterborough
ZipCode
PE2 2PW
Phone Number
0800 988 0292
Pharmacist Counseling Corner

Super Strength Probiotic Max by Simply Supplements: Common Questions

Does Super Strength Probiotic Max by Simply Supplements interact with any medications?
Yes. Based on its ingredients, Super Strength Probiotic Max has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Strength Probiotic Max contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me gas or bloating?
It might, especially at higher doses or when you first start. The most common side effects are gas, bloating, and abdominal discomfort. The good news is that a review of clinical studies found these symptoms were generally mild at typical doses under 10 grams per day, and sometimes didn't show up at all compared with placebo.
What is FOS, and what's it supposed to do?
FOS — fructo-oligosaccharides — is a type of carbohydrate that acts as a prebiotic, meaning it's food for the beneficial bacteria already living in your gut. The idea is that feeding those good bacteria helps keep your digestive system balanced.
Does this actually work for any particular health issue?
The evidence isn't established yet. It's been studied for things like constipation, blood sugar, and cholesterol, but we don't have reliable proof that it works for any of those uses right now.
Is it safe to take while pregnant or breastfeeding?
We don't have safety data on file for pregnancy or lactation. Talk with your doctor or pharmacist — they can help you decide whether it's right for you during this time.
What's LactoSpore, and why is it in here?
LactoSpore is a blend of ingredient components that we don't have full details on here. It's typically included in probiotic products, but if you want to know exactly what's in it, check the label or ask us directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Strength Probiotic Max is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Strength Probiotic Max label
Sources

Sources & How We Checked

Super Strength Probiotic Max's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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